Prolonged survival after diagnosis of brain metastasis from breast cancer: contributing factors and treatment implications.

abstract：:Myoepithelioma is a rare neoplasm usually occurring in the salivary glands or the mammary glands but also, more rarely, in the thoracic cavity. The diagnosis of myoepithelioma is based on the presence of histological and immunohistochemical characteristics of myoepithelioma, but in unusual locations, the diagnosis is ...

journal_title：Japanese journal of clinical oncology

authors： Habu T,Soh J,Toji T,Shien K,Niman E,Namba K,Sato H,Yamamoto H,Sugimoto S,Yamane M,Toyooka S

更新日期：2018-09-01 00:00:00

abstract：:The prognosis of pancreatic adenocarcinoma is dismal. Hence, advances in multidisciplinary treatment strategies, including surgery, are urgently needed. Early recurrence of distant organ metastases suggests that there are occult metastases even in cases with resectable disease. Several randomized controlled trials on ...

journal_title：Japanese journal of clinical oncology

authors： Motoi F,Unno M

更新日期：2020-05-05 00:00:00

abstract：BACKGROUND:In recent times, the possibility of detecting lung cancer using microsatellite alterations (microsatellite instability and loss of heterozygosity) in DNA of bronchial washings has been explored. However, no data regarding the presence of microsatellite alterations in lung cancer are available from India, a c...

journal_title：Japanese journal of clinical oncology

authors： Malhotra P,Behera D,Srinivasan R,Majumdar S,Wali A,Mir S,Kaur R

更新日期：2004-08-01 00:00:00

abstract：Objective:The prognostic value of metabolic parameters using 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) has not been established for early non-small cell lung cancer (NSCLC). Accordingly, the authors investigated the prognostic value of metabolic parameters in terms of failure ...

journal_title：Japanese journal of clinical oncology

authors： Lee J,Lee M,Koom WS,Kim HJ,Kim WC

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:This multicenter, open-label, single-arm, Phase II study assessed the efficacy of a neoadjuvant chemotherapy with docetaxel (75 mg/m(2) q3w) followed by 5-fluorouracil 500 mg/m(2), epirubicin 100 mg/m(2) and cyclophosphamide 500 mg/m(2) q3w in patients with early-stage breast cancer. METHODS:Women with resec...

journal_title：Japanese journal of clinical oncology

authors： Iwata H,Sato N,Masuda N,Nakamura S,Yamamoto N,Kuroi K,Kurosumi M,Tsuda H,Akiyama F,Ohashi Y,Toi M

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:The optimal treatment for elderly patients with limited-disease small cell lung cancer has not been defined. We therefore performed a Phase I study for split-dose cisplatin plus etoposide combined with early concurrent accelerated hyperfractionated thoracic radiotherapy in elderly (70 years of age or older) p...

journal_title：Japanese journal of clinical oncology

authors： Okamoto K,Okamoto I,Takeda M,Kobayashi S,Takeda K,Nakamatsu K,Nishimura Y,Nakagawa K

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVES:Tepotinib (MSC2156119J) is an oral, potent and highly selective small molecule mesenchymal-epithelial transition factor (MET) inhibitor for which the recommended Phase II dose of 500 mg once daily has been defined, based on the first-in-man trial conducted in the USA and Europe. We carried out a multicenter ...

journal_title：Japanese journal of clinical oncology

authors： Shitara K,Yamazaki K,Tsushima T,Naito T,Matsubara N,Watanabe M,Sarholz B,Johne A,Doi T

更新日期：2020-08-04 00:00:00

abstract：:Among 492 patients with esophageal carcinoma who received resective surgery, 102 survived over 5 years. These 5-year survivors were analyzed according to many factors. Females had a better prognosis than males, and patients without lymph-node metastasis had a better 5-year survival rate than those with it. Ten patient...

journal_title：Japanese journal of clinical oncology

authors： Iizuka T,Kato H,Watanabe H

更新日期：1985-06-01 00:00:00

abstract：OBJECTIVE:To characterize surgical invasiveness and morbidity and to verify therapeutic efficacy, we reviewed perioperative and postoperative courses and therapeutic outcomes of patients who underwent retroperitoneal lymph node dissection (RPLND) for testicular germ cell cancers. METHODS:The study included 31 patients...

journal_title：Japanese journal of clinical oncology

authors： Tanaka T,Kitamura H,Kunishima Y,Takahashi S,Takahashi A,Masumori N,Itoh N,Tsukamoto T

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVE:To investigate the regulative effect of microRNA-338-3p on colorectal carcinoma cell invasion and migration. METHODS:The microRNA-338-3p expression pattern of colorectal carcinoma tissues and cell lines was detected by real-time reverse transcriptase polymerase chain reaction. The protein level of smoothened...

journal_title：Japanese journal of clinical oncology

authors： Xue Q,Sun K,Deng HJ,Lei ST,Dong JQ,Li GX

更新日期：2014-01-01 00:00:00

abstract：:The techniques of aseptic procedures in the laminar airflow room (LAF) were evaluated in 110 adult patients undergoing antileukemic chemotherapy for remission induction. The patients were divided into three groups according to the regimens: Group A, consisting of 20 patients who stayed in the LAF and received the gown...

journal_title：Japanese journal of clinical oncology

authors： Takeo H,Sakurai T,Amaki I

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Chromosomal numerical abnormality (CNA) is a characteristic of breast cancer as with other common solid cancers. Multiple mammary carcinomas are also sometimes encountered in the ipsilateral breast. Deciding whether they are multicentric (arising independently) or multifocal (of the same origin) has been a c...

journal_title：Japanese journal of clinical oncology

authors： Nakamura R,Song JP,Isogaki J,Kitayama Y,Sugimura H

更新日期：2003-09-01 00:00:00

abstract：:Of the patients with colorectal cancer, there are some with hereditary disorders such as familial polyposis coli, Gardner's syndrome, Turcot's syndrome, and cancer family syndrome in which colorectal adenocarcinoma develops at a significantly high frequency, and these hereditary diseases are very important and interes...

journal_title：Japanese journal of clinical oncology

authors： Ushio K

更新日期：1985-04-01 00:00:00

abstract：:A 72-year-old man was found to have a 12 mm solid lesion in the pancreatic tail and an 8 mm cystic lesion in the body of the pancreas by computed tomography carried out during a routine follow-up study of his adult-onset diabetes mellitus. A distal pancreatectomy was performed revealing the pancreas to have an adenoca...

journal_title：Japanese journal of clinical oncology

authors： Yoshida J,Ozaki H,Yamamoto J,Kosuge T,Takayasu K,Muramatsu Y,Mukai K

更新日期：1991-12-01 00:00:00

abstract：:A rare case of adult T-cell leukemia/lymphoma with a giant exophytic gastric tumor invading the anterior abdominal wall is presented. The patient was a 52-year-old woman, who had a history of strongyloidiasis. Although the patient was serologically positive for HTLV-I antibody, there were no lymphoma cells in the peri...

journal_title：Japanese journal of clinical oncology

authors： Hiroyasu S,Shiraishi M,Shimabukuro M,Kusano T,Muto Y

更新日期：1996-10-01 00:00:00

abstract：:The development of PD-1 pathway inhibitors has dramatically altered the treatment of advanced/recurrent non-small-cell lung cancer patients. However, the prognostic significance of their ongoing usage is controversial, especially for patients who have not progressed for a period of time. If discontinuation has no nega...

journal_title：Japanese journal of clinical oncology

authors： Nomura S,Goto Y,Mizutani T,Kataoka T,Kawai S,Okuma Y,Murakami H,Tanaka K,Ohe Y

更新日期：2020-07-09 00:00:00

abstract：BACKGROUND:Duodenal carcinoma is very rare and its culture cell lines have rarely been established. METHODS:Tumor cells separated from a surgically resected primary tumor of duodenal carcinoma were put into culture. The patient was an 81-year-old female and had metastatic lymph nodes. We investigated the biological ch...

journal_title：Japanese journal of clinical oncology

authors： Tani M,Tanimura H,Terasawa H,Yamade N,Shono Y,Yamaue H

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:In an interim analysis of a Phase II trial in Japanese patients with pancreatic neuroendocrine tumors (panNETs), sunitinib demonstrated antitumor activity with an objective response rate (ORR) of 50% (95% confidence interval [CI], 21-79) and a median progression-free survival (PFS) of 16.8 months (95% CI, 9....

journal_title：Japanese journal of clinical oncology

authors： Ito T,Tori M,Hashigaki S,Kimura N,Sato K,Ohki E,Sawaki A,Okusaka T

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:Despite the clinical similarities triple-negative and basal-like breast cancer are not synonymous. Indeed, not all basal-like cancers are negative for estrogen receptor, progesterone receptor and HER2 expression while triple-negative also encompasses other cancer types. P53 protein appears heterogeneously exp...

journal_title：Japanese journal of clinical oncology

authors： Biganzoli E,Coradini D,Ambrogi F,Garibaldi JM,Lisboa P,Soria D,Green AR,Pedriali M,Piantelli M,Querzoli P,Demicheli R,Boracchi P,Nenci I,Ellis IO,Alberti S

更新日期：2011-02-01 00:00:00

abstract：:Hepatobiliary and pancreatic cancers have poor outcomes. Clinical staging is useful for predicting survival and selecting treatment options. The 8th edition of tumor-node metastasis (TNM) was published in 2016 and came into effect from 2018. Regarding liver cancer (hepatocellular carcinoma), tumour size and vascular i...

journal_title：Japanese journal of clinical oncology

authors： Ueno M,Morizane C,Ikeda M,Okusaka T,Ishii H,Furuse J

更新日期：2019-12-27 00:00:00

abstract：Purpose:To investigate the usefulness of screening for patient symptoms as the fifth vital sign using an electronic medical recording system. Patients and methods:In the electronic medical recording system, all admitted patients received routine nurse-based assessment of discomfort (defined as any physical symptom) at...

journal_title：Japanese journal of clinical oncology

authors： Naito AS,Sakuma Y,Kinoshita H,Ito T,Mimatsu S,Tarumi A,Kiyohara E,Morita T

更新日期：2017-05-01 00:00:00

abstract：:New drug delivery systems for cis-diamminedichloroplatinum (CDDP) incorporated into vehicles, such as polymethylmethacrylate (PMMA), fibrin glue (F.G.), alpha-tricalciumphosphate (TCP) and ethylenevinyleacetate copolymer (Polymer) were examined using a rat osteosarcoma model. The materials containing CDDP were directl...

journal_title：Japanese journal of clinical oncology

authors： Miura S,Mii Y,Miyauchi Y,Ohgushi H,Morishita T,Hohnoki K,Aoki M,Tamai S,Konishi Y

更新日期：1995-06-01 00:00:00

abstract：:We encountered a patient with hepatocellular carcinoma (HCC) with peritoneal dissemination and needle tract implantation, both of which were strongly suspected to have been caused by percutaneous needle biopsy. The patient was a 65-year-old man. Partial hepatectomy of subsegment VI had been performed following the dia...

journal_title：Japanese journal of clinical oncology

authors： Takahashi H,Konishi M,Nakagohri T,Inoue K,Takahashi S,Tanizawa Y,Monden M,Kinoshita T

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:Breast cancer is a heterogeneous disease. The aim of this prospective study, in which fluorescence in situ hybridization was used to determine human epidermal growth factor receptor 2 status in primary breast cancers and in the lymph node metastases, was to verify the stability of human epidermal growth facto...

journal_title：Japanese journal of clinical oncology

authors： Aoyama K,Kamio T,Nishikawa T,Kameoka S

更新日期：2010-07-01 00:00:00

abstract：:Mucin-producing carcinoma of the thyroid is rare and its histogenesis has been debated. The first case was reported by Diaz-Perez et al. (1976). We herein report the sixth case of mucin-producing carcinoma of the thyroid which was discovered in a 72-year-old Japanese woman. This patient was admitted with a 10-year his...

journal_title：Japanese journal of clinical oncology

authors： Harada T,Shimaoka K,Hiratsuka M,Hirokawa M,Tsukayama C

更新日期：1984-09-01 00:00:00

abstract：:Advanced esophageal cancer patients with extensive lymph node metastases show extremely poor prognosis and the long-term outcome is poorer with the involvement of more lymph nodes. We report here a long-surviving case of advanced esophageal cancer with histologically 34 lymph node metastases, in which surgical resecti...

journal_title：Japanese journal of clinical oncology

authors： Shigemitsu K,Naomoto Y,Shirakawa Y,Haisa M,Gunduz M,Tanaka N

更新日期：2002-08-01 00:00:00

abstract：:Germline deletion of the 3' portion of the Epithelial Cell Adhesion Molecule (EPCAM) gene located 5' upstream of MutS Homolog 2 (MSH2) is a novel mechanism for its inactivation in Lynch syndrome. However, its contribution in Japanese Lynch syndrome patients is poorly understood. Moreover, somatic events inactivating t...

journal_title：Japanese journal of clinical oncology

authors： Eguchi H,Kumamoto K,Suzuki O,Kohda M,Tada Y,Okazaki Y,Ishida H

更新日期：2016-02-01 00:00:00

abstract：:Human lymphoblastoid interferon-alpha was administered intramuscularly at a dose of 5 x 10(6) units/day to 20 metastatic renal cell carcinoma patients. For potentiating the antitumor effect of interferon, cimetidine was also given to them orally at a dose of 800 mg/day. The combination therapy obtained a complete resp...

journal_title：Japanese journal of clinical oncology

authors： Kotake T,Kinouchi T,Saiki S,Kuroda M,Miki T,Kiyohara H,Usami M

更新日期：1991-02-01 00:00:00

abstract：OBJECTIVE:The CpG island methylator phenotype is strongly associated with poor survival in neuroblastomas. Neuroblastomas with the CpG island methylator phenotype include almost all neuroblastomas with MYCN amplification, and, even among neuroblastomas without MYCN amplification, have worse prognosis. At the same time,...

journal_title：Japanese journal of clinical oncology

authors： Asada K,Watanabe N,Nakamura Y,Ohira M,Westermann F,Schwab M,Nakagawara A,Ushijima T

更新日期：2013-06-01 00:00:00

abstract：:A 56-year-old Japanese man in whom a descending colon carcinoma had been resected underwent a high orchitectomy for metastatic epididymis from the colon. Metastatic carcinoma from the digestive organs to the spermatic cord (SC) and/or the intrascrotal contents (ISC) is rare. Fifty-four Japanese patients with metastasi...

journal_title：Japanese journal of clinical oncology

authors： Kanno K,Ohwada S,Nakamura S,Ohya T,Iino Y,Morishita Y,Hayashi M,Yamanaka H,Fukusato T,Koyama T

更新日期：1994-12-01 00:00:00