Myoepithelioma occurring in the posterior mediastinum harboring EWSR1 rearrangement: a case report.

abstract：OBJECTIVE:To determine the antitumor activity and toxicity of weekly hepatic arterial infusion (HAI) of 5-fluorouracil (5-FU) for liver metastases from colorectal cancer. In addition, the present study also evaluated the efficacy of second-line chemotherapy after termination of HAI. METHODS:A retrospective study was d...

journal_title：Japanese journal of clinical oncology

authors： Hosokawa A,Yamada Y,Shimada Y,Muro K,Matsumura Y,Fujita S,Akasu T,Moriya Y,Shirao K

更新日期：2003-03-01 00:00:00

abstract：:Germline deletion of the 3' portion of the Epithelial Cell Adhesion Molecule (EPCAM) gene located 5' upstream of MutS Homolog 2 (MSH2) is a novel mechanism for its inactivation in Lynch syndrome. However, its contribution in Japanese Lynch syndrome patients is poorly understood. Moreover, somatic events inactivating t...

journal_title：Japanese journal of clinical oncology

authors： Eguchi H,Kumamoto K,Suzuki O,Kohda M,Tada Y,Okazaki Y,Ishida H

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Stage III colorectal cancer is an indication for adjuvant chemotherapy; however, there is no definite view on the selection of regimen. If the recurrence can be predicted, it can serve as the indicator of regimen selection. The present study aimed to predict the recurrence of stage III colorectal cancer by c...

journal_title：Japanese journal of clinical oncology

authors： Ishikawa S,Sawayama H,Matsuo A,Uchino R,Honda S,Hirota M,Baba H

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:A combination of cisplatin and vinorelbine chemotherapy is effective in cases of advanced non-small cell lung cancer, but the optimum administration schedule for both drugs has not yet been defined. The aim of this study was to determine the maximum dose of vinorelbine that can be tolerated while receiving a...

journal_title：Japanese journal of clinical oncology

authors： Hotta K,Sekine I,Tamura T,Sawada M,Watanabe H,Kusaba H,Akiyama Y,Inoue A,Shimoyama T,Nokihara H,Ueda Y,Yamamoto N,Kunitoh H,Ohe Y,Kodama T,Saijo N

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVE:The cell cycle profile test is suggested to be an independent prognostic indicator for breast cancer patients. To further clarify the prognostic value, we applied this to breast cancer patients treated with postoperative 5-fluorouracil-based chemotherapy. METHODS:A total of 153 breast cancer patients, who we...

journal_title：Japanese journal of clinical oncology

authors： Kurebayashi J,Kanomata N,Kozuka Y,Moriya T,Kikukawa N,Kawasaki Y,Harada S,Tamura S,Nakayama S,Ishihara H,Noguchi S,Sonoo H

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:We evaluated the efficacy of our quality assurance (QA) program of radiation therapy (RT) in a prospective phase II study. This is the first description of the experience of the Japan Radiation Oncology Group (JAROG) with this program. METHODS:Clinical records, all diagnostic radiological films or color pho...

journal_title：Japanese journal of clinical oncology

authors： Isobe K,Kagami Y,Higuchi K,Kodaira T,Hasegawa M,Shikama N,Nakazawa M,Fukuda I,Nihei K,Ito K,Teshima T,Oguchi M,Japan Radiation Oncology Group (JAROG).

更新日期：2007-02-01 00:00:00

abstract：:The prognosis of pancreatic adenocarcinoma is dismal. Hence, advances in multidisciplinary treatment strategies, including surgery, are urgently needed. Early recurrence of distant organ metastases suggests that there are occult metastases even in cases with resectable disease. Several randomized controlled trials on ...

journal_title：Japanese journal of clinical oncology

authors： Motoi F,Unno M

更新日期：2020-05-05 00:00:00

abstract：BACKGROUND:CD10 is a cell surface metalloproteinase expressed by a variety of normal cell types, including lymphoid precursor cells, germinal center B lymphocytes and some epithelial cells. Although accumulating data indicate that CD10 expression by stromal cells is involved in colorectal carcinogenesis and it is a nov...

journal_title：Japanese journal of clinical oncology

authors： Huang WB,Zhou XJ,Chen JY,Zhang LH,Meng K,Ma HH,Lu ZF

更新日期：2005-05-01 00:00:00

abstract：:Bone marrow transplantation (BMT) was started in Hokkaido in 1985. In the present report we have reviewed the clinical outcome of patients treated with BMT for hematological diseases in Hokkaido. Fifty-eight allogeneic and 19 autologous transplants were registered by December 1991. The underlying diseases consisted of...

journal_title：Japanese journal of clinical oncology

authors： Hashino S,Imamura M,Kasai M,Higa T,Naohara T,Sakamaki S,Matsunaga T,Kohgo Y,Kohda K,Nakazawa O

更新日期：1993-06-01 00:00:00

abstract：:Cancer-associated retinopathy is a rare paraneoplastic syndrome that is often associated with small-cell lung cancer. It is caused by an autoantibody to the 23 kDa photoreceptor protein, recoverin. A small number of reports have described effective treatment for the disease. We report two cases of cancer-associated re...

journal_title：Japanese journal of clinical oncology

authors： Sakamori Y,Kim YH,Okuda C,Togashi Y,Kinose D,Masago K,Mio T,Uji A,Mishima M

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:The optimal management of elderly patients with limited-disease small cell lung cancer (LD-SCLC) has not been established. METHODS:The records of elderly (>or=70 years of age) patients with LD-SCLC who had been treated with etoposide and cisplatin chemotherapy with early concurrent twice-daily thoracic radio...

journal_title：Japanese journal of clinical oncology

authors： Okamoto K,Okamoto I,Takezawa K,Tachibana I,Fukuoka M,Nishimura Y,Nakagawa K

更新日期：2010-01-01 00:00:00

abstract：:An analysis is presented of the histopathologic, clinical and prognostic features of malignant lymphomas (MLs) treated at the University of the Philippines-Philippine General Hospital Medical Center, Manila, between 1975 and 1981. There were 434 malignant lymphomas, constituting 3.86% of all cancers studied at this in...

journal_title：Japanese journal of clinical oncology

authors： Calderon B,Villalon A,Augustin B,Javier B,Zamuco J,Mori S

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVE:Laminin-332, a marker of epithelial-mesenchymal transition, is composed of a heterotrimer of α3, β3 and γ2 chains that regulates cell adhesion and migration. This study aimed to disclose the respective clinical significance of laminin β3 immunoexpression in colorectal cancer as a prognostic factor and a predi...

journal_title：Japanese journal of clinical oncology

authors： Fukazawa S,Shinto E,Tsuda H,Ueno H,Shikina A,Kajiwara Y,Yamamoto J,Hase K

更新日期：2015-06-01 00:00:00

abstract：:An in vitro monolayer model for cancer invasion was developed, comprising cultured layers of human pleura-derived mesothelial cells (PM cells). The cells were isolated from normal human pleura at autopsy and cultured in RPMI-1640 supplemented with 10% fetal calf serum; they were polygonal in shape, forming a pavement-...

journal_title：Japanese journal of clinical oncology

authors： Horai T,Imamura F,Nakae T,Nakamura S,Mukai M,Shinkai K,Higashino K,Akedo H

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVE:Trop-1/Ep-CAM modulates growth and survival of transformed cells, and it is highly expressed in most carcinomas including breast cancer. Only membranous staining is typically considered in evaluating Trop-1/epithelial cell adhesion molecule (Ep-CAM) expression in tumor cells. However, there is evidence of ret...

journal_title：Japanese journal of clinical oncology

authors： Alberti S,Ambrogi F,Boracchi P,Fornili M,Querzoli P,Pedriali M,La Sorda R,Lattanzio R,Tripaldi R,Piantelli M,Biganzoli E,Coradini D

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:Oral fluoropyrimidine plus cisplatin is a standard treatment for advanced gastric cancer, but patients with severe peritoneal metastasis often cannot tolerate this regimen. The aim of this study was to assess the feasibility of fluorouracil, l-leucovorin and paclitaxel therapy in such patients. METHODS:In th...

journal_title：Japanese journal of clinical oncology

authors： Iwasa S,Goto M,Yasui H,Nishina T,Takahari D,Nakayama N,Taira K,Kusaba H,Fuse N,Hironaka S,Shimada Y,Nakajima TE

更新日期：2012-09-01 00:00:00

abstract：:The PRECIOUS study (UMIN000018202) is being conducted as a multicenter, randomized, open-label Phase III study to determine if retreatment with pertuzumab is more effective than conventional treatment in HER2-positive locally advanced (LA)/metastatic breast cancer (MBC) patients previously treated with pertuzumab, tra...

journal_title：Japanese journal of clinical oncology

authors： Yamamoto Y,Iwata H,Ueno T,Taira N,Kashiwaba M,Takahashi M,Tada H,Tsugawa K,Toyama T,Niikura N,Hara F,Fujisawa T,Yoshinami T,Saji S,Takano T,Masuda N,Morita S,Toi M,Ohno S

更新日期：2018-09-01 00:00:00

abstract：:Pure red cell aplasia (PRCA) rarely occurs in non-thymic lymphoproliferative disorders. The present article describes a patient with non-Hodgkin's lymphoma (follicular, mixed type), who concurrently developed PRCA and warm type autoimmune hemolytic anemia during the clinical course. The PRCA and hemolytic anemia were ...

journal_title：Japanese journal of clinical oncology

authors： Suzuki A,Takahashi T,Taniguchi A,Kotake C,Seo T,Toda T,Kobayashi K,Tsukamoto N,Fukumoto M

更新日期：1991-10-01 00:00:00

abstract：:Immunoperoxidase staining for human keratin proteins was performed cytologically on samples from 90 patients with malignant tumors, and histologically on samples from 164 patients with malignant tumors. At the cytological level, almost all tumor cells not only in squamous cell carcinoma but also in nonsquamous cell ca...

journal_title：Japanese journal of clinical oncology

authors： Yagi Y,Imamura Y,Saku T,Shimotsu T,Hatae M,Yagi S

更新日期：1986-03-01 00:00:00

abstract：:Cancer is the leading cause of mortality in Singapore. The age-standardized incidence rates continue to increase as the population grows and ages, and the influence of environmental and lifestyle choices bear their consequences. The increase is most marked in colorectal, breast and prostate cancers, mirroring the most...

journal_title：Japanese journal of clinical oncology

authors： Teo MC,Soo KC

更新日期：2013-03-01 00:00:00

abstract：:Twenty-six patients with advanced bronchogenic adenocarcinoma or large cell carcinoma were treated by combination chemotherapy consisting of Ftorafur, adriamycin and mitomycin C (FAM II). The patients had not received prior chemotherapy and were not eligible for radiotherapy and surgery. The overall response rate was ...

journal_title：Japanese journal of clinical oncology

authors： Salvati F,Cruciani AR,De Marinis A,Nunziati F,Portalone L

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND:In women, osteoporosis is a common chronic disease that induces spinal compression and femoral neck fractures, resulting in life-threatening complications. It is very important to identify risk factors in order to prevent this disorder. Bone destruction is a well-recognized complication in a variety of neopl...

journal_title：Japanese journal of clinical oncology

authors： Hung YC,Yeh LS,Chang WC,Lin CC,Kao CH

更新日期：2002-10-01 00:00:00

abstract：:This report describes a 78-year-old woman with insulinoma, treated with a combination of diphenylhydantoin and a calcium antagonist. The effectiveness of 200 mg of diphenylhydantoin and 180 mg of diltiazem was evaluated by measuring the levels of plasma glucose, immunoreactive insulin and immunoreactive insulin/plasma...

journal_title：Japanese journal of clinical oncology

authors： Imanaka S,Matsuda S,Ito K,Matsuoka T,Okada Y

更新日期：1986-03-01 00:00:00

abstract：:We reviewed 1074 surgically treated patients with biliary tract cancer (gallbladder 564, bile duct 510) in Niigata prefecture in the five-year period from 1982 to 1986. Analyses of regional distributions revealed the incidence of gallbladder cancer to be highest in the Ka-etsu district (northern part of prefecture) an...

journal_title：Japanese journal of clinical oncology

authors： Kato K,Akai S

更新日期：1990-03-01 00:00:00

abstract：OBJECTIVE:Apocrine carcinoma, a subtype of invasive ductal carcinoma of the breast, expresses androgen receptor (AR), but often lacks estrogen receptor (ER) and progesterone receptor (PgR). In the present study, the author immunohistochemically defined apocrine-type carcinoma as ER-/PgR-/AR+ invasive ductal carcinoma a...

journal_title：Japanese journal of clinical oncology

authors： Tsutsumi Y

更新日期：2012-05-01 00:00:00

abstract：:Morphometrical analysis was performed on cells of bladder carcinomas taken from patients who had undergone surgery at the National Cancer Center Hospital. Ten cases each of the following groups were compared as to the nuclear area, standard deviation of nuclear areas, cytoplasmic area, and nuclear/cytoplasmic ratio: n...

journal_title：Japanese journal of clinical oncology

authors： Hanai S,Kishi K,Watanabe S,Shimosato Y

更新日期：1985-12-01 00:00:00

abstract：BACKGROUND:In an interim analysis of a Phase II trial in Japanese patients with pancreatic neuroendocrine tumors (panNETs), sunitinib demonstrated antitumor activity with an objective response rate (ORR) of 50% (95% confidence interval [CI], 21-79) and a median progression-free survival (PFS) of 16.8 months (95% CI, 9....

journal_title：Japanese journal of clinical oncology

authors： Ito T,Tori M,Hashigaki S,Kimura N,Sato K,Ohki E,Sawaki A,Okusaka T

更新日期：2019-04-01 00:00:00

abstract：:Cancer originating in the biliary tract can be classified as bile duct cancer (cholangiocarcinoma), gallbladder cancer, or ampullary cancer. Bile duct cancer is further divided to intrahepatic, perihilar and distal bile duct subtypes according to the anatomical location of the tumor. The biological characteristics of ...

journal_title：Japanese journal of clinical oncology

authors： Nara S,Esaki M,Ban D,Takamoto T,Shimada K,Ioka T,Okusaka T,Ishii H,Furuse J

更新日期：2020-12-16 00:00:00

abstract：OBJECTIVES:To examine the association between local recurrence and distant metastasis or disease-specific survival and identify independent factor predictors for local recurrence. METHODS:We identified a study population of 146 consecutive patients treated surgically for invasive bladder cancer at our institution betw...

journal_title：Japanese journal of clinical oncology

authors： Ide H,Kikuchi E,Miyajima A,Nakagawa K,Ohigashi T,Nakashima J,Oya M

更新日期：2008-05-01 00:00:00

abstract：:We present a case of pancreatic leiomyosarcoma with liver metastasis diagnosed by liver tumor biopsy. A 66-year-old man had a pancreatic tumor and hepatic tumors, which were hypoechoic and mixed echoic on ultrasonography, respectively. They were stained in enhanced computed tomography and angiography. A fine needle as...

journal_title：Japanese journal of clinical oncology

authors： Ishii H,Okada S,Okazaki N,Nose H,Yoshimori M,Aoki K,Tsuda H,Hirohashi S

更新日期：1994-02-01 00:00:00