Reduced-intensity hematopoietic stem cell transplantation (RIST) for solid malignancies.

abstract：:A randomized phase III trial was initiated in Japan in August 2019 to confirm the superiority of preoperative chemoradiotherapy followed by surgery plus adjuvant chemotherapy compared to the standard treatment, i.e. surgery plus adjuvant chemotherapy, for locally recurrent rectal cancer in local relapse-free survival....

journal_title：Japanese journal of clinical oncology

authors： Kadota T,Tsukada Y,Ito M,Katayama H,Mizusawa J,Nakamura N,Ito Y,Bando H,Ando M,Onaya H,Fukuda H,Kanemitsu Y

更新日期：2020-08-04 00:00:00

abstract：OBJECTIVE:Trop-1/Ep-CAM modulates growth and survival of transformed cells, and it is highly expressed in most carcinomas including breast cancer. Only membranous staining is typically considered in evaluating Trop-1/epithelial cell adhesion molecule (Ep-CAM) expression in tumor cells. However, there is evidence of ret...

journal_title：Japanese journal of clinical oncology

authors： Alberti S,Ambrogi F,Boracchi P,Fornili M,Querzoli P,Pedriali M,La Sorda R,Lattanzio R,Tripaldi R,Piantelli M,Biganzoli E,Coradini D

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Oral carmofur, either as a single or in combination with other chemotherapeutic agents, has been used as adjuvant chemotherapy for curatively resected colon cancer patients. Past trials and meta-analyses indicate that it is somewhat effective in extending survival of patients with this cancer. The objective ...

journal_title：Japanese journal of clinical oncology

authors： Sakamoto J,Hamada C,Rahman M,Kodaira S,Ito K,Nakazato H,Ohashi Y,Yasutomi M

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Giant cell tumor (GCT) of bone is a rare and unpredictable lesion. Its standard treatment has ranged from surgical curettage to wide resection and varying oncological and functional results have been reported. METHODS:A retrospective review of 47 patients (17 males and 30 females) with GCT of bone was perfo...

journal_title：Japanese journal of clinical oncology

authors： Oda Y,Miura H,Tsuneyoshi M,Iwamoto Y

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:Vital dye-guided sentinel node biopsy is affordable in most hospitals, but may be of limited accuracy in identifying all sentinel nodes. Leaving sentinel nodes in the axilla may result in a false nodal staging of breast carcinomas. METHODS:From a series of 112 successful sentinel lymph node biopsies with Pa...

journal_title：Japanese journal of clinical oncology

authors： Cserni G,Rajtár M,Boross G

更新日期：2000-06-01 00:00:00

abstract：OBJECTIVE:The prognosis of breast cancer-derived brain metastasis is poor, but new drugs and recent therapeutic strategies have helped extend survival in patients. Prediction of therapeutic responses and outcomes is not yet possible, however. In a retrospective study, we examined prognostic factors in patients with bre...

journal_title：Japanese journal of clinical oncology

authors： Honda Y,Aruga T,Yamashita T,Miyamoto H,Horiguchi K,Kitagawa D,Idera N,Goto R,Kuroi K

更新日期：2015-08-01 00:00:00

abstract：:A thyroid ultrasound examination programme has been conducted in Fukushima Prefecture, Japan, after the nuclear disaster in 2011. Although remarkably high prevalence of thyroid cancer was observed, no relevant quantitative evaluation was conducted. We calculated the observed/expected (O/E) ratio of thyroid cancer prev...

journal_title：Japanese journal of clinical oncology

authors： Katanoda K,Kamo K,Tsugane S

更新日期：2016-03-01 00:00:00

abstract：:One hundred and one cases of lung cancer were immunohistochemically studied for stainability with Leu-7 (anti-myelin fiber associated glycoprotein) and OKT-9 (anti-transferrin receptor) monoclonal antibodies. All small cell carcinomas and carcinoid tumors were positively stained by Leu-7, and 22 of 41 differentiated a...

journal_title：Japanese journal of clinical oncology

authors： Sato Y,Watanabe S,Kodama T,Goto M,Shimosato Y

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND:Usually, total and filtered platinum concentrations in plasma are monitored after cisplatin administration. However, these concentrations represent a mixture of unchanged cisplatin and metabolites. In this work, we studied population pharmacokinetic analysis based on these platinum concentrations. METHODS:T...

journal_title：Japanese journal of clinical oncology

authors： Hanada K,Nishijima K,Ogata H,Atagi S,Kawahara M

更新日期：2001-05-01 00:00:00

abstract：:The localization of acidic fibroblast growth factor (aFGF) and basic fibroblast growth factor (bFGF) was investigated immunohistochemically in human benign and malignant thyroid lesions. Immunostaining for aFGF and bFGF displayed diffuse or granular deposits of the reaction products in the cytoplasm of neoplastic cell...

journal_title：Japanese journal of clinical oncology

authors： Kodama M,Daa T,Kashima K,Yokoyama S,Nakayama I,Noguchi S

更新日期：1994-04-01 00:00:00

abstract：:The frequency of expression and localization of cripto-1 (CR-1), amphiregulin (AR), transforming growth factor alpha (TGF alpha), epidermal growth factor receptor (EGFR) and erbB-2 were examined by immunohistochemistry in 45 carcinomas and adjacent non-involved normal colon mucosa. Thirty (66.7%), 24 (53.3%), 23 (51.1...

journal_title：Japanese journal of clinical oncology

authors： Saeki T,Salomon DS,Johnson GR,Gullick WJ,Mandai K,Yamagami K,Moriwaki S,Tanada M,Takashima S,Tahara E

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Angiosarcoma is an aggressive and malignant neoplasm. Primary hepatic angiosarcoma is extremely rare and accounts for only approximately 5% of all angiosarcomas. Therefore, many doctors do not know enough about this disease; this lack of knowledge motivated us to perform this study. METHODS:We carried out a...

journal_title：Japanese journal of clinical oncology

authors： Zeng D,Cheng J,Gong Z,Chen J,Long H,Zhu B

更新日期：2020-05-05 00:00:00

abstract：:Eight cultured cell lines were established from human small cell lung cancers. Every cell line showed the morphological and biochemical characteristics of small cell cancer. Changes in cell characteristics were observed in many of these cell lines when culture conditions were changed: "oat cell type" changed to "inter...

journal_title：Japanese journal of clinical oncology

authors： Terasaki T,Shimosato Y,Nakajima T,Tsumuraya M,Morinaga S,Hirohashi S,Yamaguchi K,Kato K,Ichinose H,Nagatsu T

更新日期：1986-09-01 00:00:00

abstract：:Chemoradiation is potentially curative for esophageal cancer in various stages, but local failure is a major problem. The present case was a 49-year-old male diagnosed with advanced esophageal cancer with an esophago-bronchial fistula and lymph node metastasis. Histological diagnosis by biopsy was adenosquamous cell c...

journal_title：Japanese journal of clinical oncology

authors： Morihiro M,Boku N,Ohtsu A,Miyamoto S,Ishikura S

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:This study was performed to review retrospectively the clinical course of chronic rectal bleeding as a complication of external beam radiation therapy for localized prostate cancer and to analyze the relationship between technical parameters of radiation therapy and the complications. METHODS:Seventy-one pa...

journal_title：Japanese journal of clinical oncology

authors： Kitamura K,Shirato H,Suzuki K,Shinohara N,Demura T,Harabayashi T,Nishioka T,Kagei K,Takayama N,Shinno Y,Kawakura K,Koyanagi T,Miyasaka K

更新日期：2000-05-01 00:00:00

abstract：:Over the past 10 years, immunotherapy with immune checkpoint inhibitors has revolutionized the management of various cancers. However, immunotherapy in breast cancer has not been successful. Breast cancer has long been recognized as an immunologically 'cold' tumor, although a higher frequency of tumor-infiltrating lym...

journal_title：Japanese journal of clinical oncology

authors： Noguchi E,Shien T,Iwata H

更新日期：2020-12-15 00:00:00

abstract：:In order to determine whether the epidemiological characteristics of lung cancer have changed within a certain period of time in Taiwan and to propose some causative factors for its rapid rate of increase we performed chronological and epidemiological studies based on the analysis of: (1) available vital statistics an...

journal_title：Japanese journal of clinical oncology

authors： Yang SP,Luh KT,Kuo SH,Lin CC

更新日期：1984-03-01 00:00:00

abstract：Background:Gliomas are highly malignant brain tumors. Aberrant activation of NF-κB plays a crucial role in tumor progression. Method:ELISA assay was used to detect NF-κB activity in glimoas cells with different treatments. PPP3CC expression was evaluated by qRT-PCR and western blot assay. Kaplan-Meier analysis estimat...

journal_title：Japanese journal of clinical oncology

authors： Wang H,Zhao S,Chen B,Fu C,Dang Y,Fang P,Wang J,Wang N,Liu L

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Angiogenesis is required for growth and metastasis of colorectal cancer (CRC), and several positive regulators of tumor angiogenesis have been identified. Cyclooxygenase-2 (COX-2), known to be elevated in several human cancers, regulates angiogenesis by inducing angiogenic factors. The aim of this study was ...

journal_title：Japanese journal of clinical oncology

authors： Nakamoto RH,Uetake H,Iida S,Kolev YV,Soumaoro LT,Takagi Y,Yasuno M,Sugihara K

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:This study was conducted to evaluate the efficacy and safety of pegylated liposomal doxorubicin (PLD) in Japanese patients with Müllerian carcinoma having a therapeutic history of platinum-based chemotherapy. METHODS:Patients who were diagnosed with Müllerian carcinoma (epithelial ovarian carcinoma, primary ...

journal_title：Japanese journal of clinical oncology

authors： Katsumata N,Fujiwara Y,Kamura T,Nakanishi T,Hatae M,Aoki D,Tanaka K,Tsuda H,Kamiura S,Takehara K,Sugiyama T,Kigawa J,Fujiwara K,Ochiai K,Ishida R,Inagaki M,Noda K

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:Human papillomavirus vaccines are being introduced worldwide and are expected to reduce the incidence of cervical cancer. Here we report a cross-sectional study using a validated human papillomavirus genotyping method to reveal the human papillomavirus prevalence and genotype distribution in Japanese women wi...

journal_title：Japanese journal of clinical oncology

authors： Azuma Y,Kusumoto-Matsuo R,Takeuchi F,Uenoyama A,Kondo K,Tsunoda H,Nagasaka K,Kawana K,Morisada T,Iwata T,Aoki D,Kukimoto I

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:To retrospectively examine the outcomes of hypofractionated stereotactic radiation therapy in three to five fractions for vestibular schwannomas. METHODS:Twenty-five patients with 26 vestibular schwannomas were treated with hypofractionated stereotactic radiation therapy using a CyberKnife. The vestibular sc...

journal_title：Japanese journal of clinical oncology

authors： Morimoto M,Yoshioka Y,Kotsuma T,Adachi K,Shiomi H,Suzuki O,Seo Y,Koizumi M,Kagawa N,Kinoshita M,Hashimoto N,Ogawa K

更新日期：2013-08-01 00:00:00

abstract：:We report on an inflammatory pseudotumor of the spleen. A 72-year-old woman visited our hospital complaining of nausea. Physical examination and laboratory investigations were unremarkable. Ultrasonography, computed tomography, magnetic resonance imaging and angiography showed a hypovascular splenic mass measuring abo...

journal_title：Japanese journal of clinical oncology

authors： Noguchi H,Kondo H,Kondo M,Shiraiwa M,Monobe Y

更新日期：2000-04-01 00:00:00

abstract：:Projecting cancer mortality is fundamental to the process of planning cancer control. Although the prefecture is one of the main units for the implementation and evaluation of cancer control in Japan, a long-term detailed future projection of cancer mortality has not been conducted by prefecture. The main objective of...

journal_title：Japanese journal of clinical oncology

authors： Fukui K,Ito Y,Nakayama T

更新日期：2019-04-01 00:00:00

abstract：:The clinical, hematological and pathological features of the adult T-cell leukemia (ATL)-related diseases and their cell membrane phenotypes in the Nagasaki district, one of the ATL-endemic areas, were delineated to compare them with those of adult T-cell leukemia-lymphoma (ATLL). In addition, the participation of ATL...

journal_title：Japanese journal of clinical oncology

authors： Kinoshita K,Amagasaki T,Yamada Y,Ikeda S,Momita S,Toriya K,Kamihira S,Ichimaru M

更新日期：1983-01-01 00:00:00

abstract：:Although malignant lymphoma of the breast is a rare disease, we recently experienced a high incidence of central nervous system (CNS) involvement. Thus, we retrospectively reviewed clinical records of 921 patients with breast tumors, treated from 1990 to 2002, to examine CNS involvement. Eight patients were found to h...

journal_title：Japanese journal of clinical oncology

authors： Yamazaki H,Hanada M,Kitada M,Kuyama J,Sato T,Nishikubo M,Ishida T,Inoue T,Inoue T

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVE:The correlations of serum interleukin-6 and soluble interleukin-6 receptor concentrations with clinicopathological features and survival of patients with colorectal cancer were studied. METHODS:We measured the serum levels of interleukin-6 and soluble interleukin-6 receptor in 99 colorectal cancer patients a...

journal_title：Japanese journal of clinical oncology

authors： Yeh KY,Li YY,Hsieh LL,Lu CH,Chou WC,Liaw CC,Tang RP,Liao SK

更新日期：2010-06-01 00:00:00

abstract：:Uterine inversion caused by uterine sarcoma is a rare condition with 12 reported cases to date according to a MEDLINE search. We report two cases of this rare condition. A 71- and a 72-year-old woman presented with uterine sarcomas rapidly extruded into the vagina. In both cases, magnetic resonance imaging (MRI) scans...

journal_title：Japanese journal of clinical oncology

authors： Takano K,Ichikawa Y,Tsunoda H,Nishida M

更新日期：2001-01-01 00:00:00

abstract：:Adenoid cystic carcinoma of the esophagus with multiple liver metastases was found in a 77-year-old Japanese female in October, 1991. Combination chemotherapy, including etoposide (VP-16) and tegafur (FT) allowed the patient to survive for approximately a year after the onset of the initial symptoms. During her course...

journal_title：Japanese journal of clinical oncology

authors： Matsumoto M,Nomiyama T,Nakae J,Nishikawa H

更新日期：1993-08-01 00:00:00

abstract：:There has been no previous report of oxaliplatin administration in patients undergoing hemodialysis. A 65-year-old female with end-stage renal disease who was undergoing hemodialysis presented with anemia in August 2005. She was diagnosed with colon cancer with multiple liver metastases. After colectomy, hepatic arter...

journal_title：Japanese journal of clinical oncology

authors： Shitara K,Munakata M,Muto O,Okada R,Mitobe S,Mino M,Ikami I,Sakata Y

更新日期：2007-07-01 00:00:00