Immunohistochemical localization of acidic and basic fibroblast growth factors in human benign and malignant thyroid lesions.

abstract：:The occurrence of multiple primary malignant neoplasms in 9,191 consecutive cases of primary gastrointestinal (GI) tract cancer from 1962 to 1981 at the National Cancer Center was analyzed. The person-years of the cases totaled 28,399.4: 185 second cancers were diagnosed clinically and 85 were first diagnosed at autop...

journal_title：Japanese journal of clinical oncology

authors： Watanabe S,Kodama T,Shimosato Y,Arimoto H,Suemasu K

更新日期：1985-04-01 00:00:00

abstract：:Germline deletion of the 3' portion of the Epithelial Cell Adhesion Molecule (EPCAM) gene located 5' upstream of MutS Homolog 2 (MSH2) is a novel mechanism for its inactivation in Lynch syndrome. However, its contribution in Japanese Lynch syndrome patients is poorly understood. Moreover, somatic events inactivating t...

journal_title：Japanese journal of clinical oncology

authors： Eguchi H,Kumamoto K,Suzuki O,Kohda M,Tada Y,Okazaki Y,Ishida H

更新日期：2016-02-01 00:00:00

abstract：:A randomized Phase II/III trial commenced in Japan in December 2013. Carboplatin plus etoposide is the current standard treatment for elderly extensive-disease small-cell lung cancer. The purpose of this study is to confirm the superiority of carboplatin plus irinotecan in terms of overall survival over carboplatin pl...

journal_title：Japanese journal of clinical oncology

authors： Eba J,Shimokawa T,Nakamura K,Shibata T,Misumi Y,Okamoto H,Yamamoto N,Ohe Y,Lung Cancer Study Group of the Japan Clinical Oncology Group.

更新日期：2015-01-01 00:00:00

abstract：:A Phase II study was started in Japan to evaluate the efficacy and safety of concurrent chemoradiotherapy with S-1 plus cisplatin in patients with unresectable locally advanced squamous cell carcinoma of the head and neck. This study began in July 2008, and a total of 45 patients will be accrued from 13 institutions w...

journal_title：Japanese journal of clinical oncology

authors： Nakamura K,Tahara M,Kiyota N,Hayashi R,Akimoto T,Fukuda H,Fujii M,Boku N

更新日期：2009-07-01 00:00:00

abstract：Objective:The prognostic value of metabolic parameters using 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) has not been established for early non-small cell lung cancer (NSCLC). Accordingly, the authors investigated the prognostic value of metabolic parameters in terms of failure ...

journal_title：Japanese journal of clinical oncology

authors： Lee J,Lee M,Koom WS,Kim HJ,Kim WC

更新日期：2018-10-01 00:00:00

abstract：:Interleukin-12 (IL-12), known to be a strong inducer of interferon-gamma (IFN-gamma), plays a vital role in activating the immune surveillance system against intracellular pathogens and malignant tumors. The authors have found that cancer patients showing marked IFN-gamma induction after inoculation with BCG-CWS (the ...

journal_title：Japanese journal of clinical oncology

authors： Hayashi A,Noda A

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:The detection of prostate-specific antigen (PSA) molecular forms such as free PSA and PSA-ACT and the use of PSA molecular ratios, especially the percentage of free to total PSA, have been reported to improve the diagnostic accuracy of prostate cancer in the patients with slightly elevated serum PSA values. ...

journal_title：Japanese journal of clinical oncology

authors： Kuriyama M,Uno H,Ueno K,Hamamoto Y,Vihn PQ,Ban Y

更新日期：1999-06-01 00:00:00

abstract：:Mucin-producing carcinoma of the thyroid is rare and its histogenesis has been debated. The first case was reported by Diaz-Perez et al. (1976). We herein report the sixth case of mucin-producing carcinoma of the thyroid which was discovered in a 72-year-old Japanese woman. This patient was admitted with a 10-year his...

journal_title：Japanese journal of clinical oncology

authors： Harada T,Shimaoka K,Hiratsuka M,Hirokawa M,Tsukayama C

更新日期：1984-09-01 00:00:00

abstract：BACKGROUND:Stage III colorectal cancer is an indication for adjuvant chemotherapy; however, there is no definite view on the selection of regimen. If the recurrence can be predicted, it can serve as the indicator of regimen selection. The present study aimed to predict the recurrence of stage III colorectal cancer by c...

journal_title：Japanese journal of clinical oncology

authors： Ishikawa S,Sawayama H,Matsuo A,Uchino R,Honda S,Hirota M,Baba H

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to detect the presence of cancer stem-like cells with bronchioalveolar stem cells (BASCs) properties and investigate the clinicopathological role of expression of OCT4 as well as the correlation with clinical outcomes in adenocarcinoma of the lung. METHODS:Specimens of 112 cases...

journal_title：Japanese journal of clinical oncology

authors： Zhang X,Han B,Huang J,Zheng B,Geng Q,Aziz F,Dong Q

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:The value of postmastectomy radiation therapy for breast cancer patients with T1-2 tumor and one to three positive nodes remains controversial. The purpose of this retrospective study was to compare the clinical outcomes of breast cancer patients with T1-2 and one to three positive nodes with and without post...

journal_title：Japanese journal of clinical oncology

authors： Huang CJ,Hou MF,Chuang HY,Lian SL,Huang MY,Chen FM,Fu OY,Lin SF

更新日期：2012-08-01 00:00:00

abstract：:Cancer-associated retinopathy is a rare paraneoplastic syndrome that is often associated with small-cell lung cancer. It is caused by an autoantibody to the 23 kDa photoreceptor protein, recoverin. A small number of reports have described effective treatment for the disease. We report two cases of cancer-associated re...

journal_title：Japanese journal of clinical oncology

authors： Sakamori Y,Kim YH,Okuda C,Togashi Y,Kinose D,Masago K,Mio T,Uji A,Mishima M

更新日期：2011-05-01 00:00:00

abstract：:The present report describes a 69-year-old man displaying the clinical features of the Cronkhite-Canada syndrome. After taking medicine for the common cold, he suffered hypogeusia and watery diarrhea, eruptions on the lower extremities and an 8 kg loss in body weight. All his finger and toenails began to fall out. He ...

journal_title：Japanese journal of clinical oncology

authors： Kaneko Y,Kato H,Tachimori Y,Watanabe H,Ushio K,Yamaguchi H,Itabashi M,Noguchi M

更新日期：1991-06-01 00:00:00

abstract：OBJECTIVE:Hepatocellular cancer (HCC) is one of the important health problems in Turkey. We aimed to determine the clinical and demographic features of HCC in the Turkish population and to evaluate the prognostic and survival features. METHOD:Two hundred and twenty-one patients with HCC from five hospitals in Turkey a...

journal_title：Japanese journal of clinical oncology

authors： Alacacioglu A,Somali I,Simsek I,Astarcioglu I,Ozkan M,Camci C,Alkis N,Karaoglu A,Tarhan O,Unek T,Yilmaz U

更新日期：2008-10-01 00:00:00

abstract：:A rare case of adult T-cell leukemia/lymphoma with a giant exophytic gastric tumor invading the anterior abdominal wall is presented. The patient was a 52-year-old woman, who had a history of strongyloidiasis. Although the patient was serologically positive for HTLV-I antibody, there were no lymphoma cells in the peri...

journal_title：Japanese journal of clinical oncology

authors： Hiroyasu S,Shiraishi M,Shimabukuro M,Kusano T,Muto Y

更新日期：1996-10-01 00:00:00

abstract：:One hundred and one cases of lung cancer were immunohistochemically studied for stainability with Leu-7 (anti-myelin fiber associated glycoprotein) and OKT-9 (anti-transferrin receptor) monoclonal antibodies. All small cell carcinomas and carcinoid tumors were positively stained by Leu-7, and 22 of 41 differentiated a...

journal_title：Japanese journal of clinical oncology

authors： Sato Y,Watanabe S,Kodama T,Goto M,Shimosato Y

更新日期：1985-09-01 00:00:00

abstract：:Pure red cell aplasia (PRCA) rarely occurs in non-thymic lymphoproliferative disorders. The present article describes a patient with non-Hodgkin's lymphoma (follicular, mixed type), who concurrently developed PRCA and warm type autoimmune hemolytic anemia during the clinical course. The PRCA and hemolytic anemia were ...

journal_title：Japanese journal of clinical oncology

authors： Suzuki A,Takahashi T,Taniguchi A,Kotake C,Seo T,Toda T,Kobayashi K,Tsukamoto N,Fukumoto M

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:It is critical to obtain informed consent from eligible patients to complete clinical trials. We investigated the factors that affect the participation rates of eligible patients. PATIENTS AND METHODS:Patients with metastatic breast cancer who were eligible for SELECT BC or SELECT BC-CONFIRM trials, randomi...

journal_title：Japanese journal of clinical oncology

authors： Ohsumi S,Mukai H,Takahashi M,Hozumi Y,Akabane H,Park Y,Tokunaga E,Takashima T,Watanabe T,Sagara Y,Kaneko T,Ohashi Y

更新日期：2020-08-04 00:00:00

abstract：OBJECTIVE:The estimated glomerular filtration rate is significantly decreased after nephroureterectomy. Deteriorating renal function likely affects the eligibility for cisplatin-based chemotherapy in patients with upper tract urothelial carcinoma. The present study was undertaken to identify preoperative factors for th...

journal_title：Japanese journal of clinical oncology

authors： Hashimoto T,Ohno Y,Nakashima J,Gondo T,Nakagami Y,Namiki K,Horiguchi Y,Yoshioka K,Ohori M,Tachibana M

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:This retrospective study analyzed the oncological and treatment outcomes of the patients with T1-T2N0 glottic cancer, who were treated with radiotherapy as initial treatment and salvaged by conservative surgery for radiation failure. METHODS:Between May 1999 and December 2010, 115 patients with glottic laryn...

journal_title：Japanese journal of clinical oncology

authors： Harada A,Sasaki R,Miyawaki D,Yoshida K,Nishimura H,Ejima Y,Kitajima K,Saito M,Otsuki N,Nibu K

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:For several decades, radiotherapy has been widely used to treat metastatic vertebral tumors. This study was designed to assess the feasibility and early clinical outcomes of high-dose radiotherapy to treat such tumors, using helical tomotherapy. METHODS:Between June 2009 and December 2011, 51 sites in 36 pat...

journal_title：Japanese journal of clinical oncology

authors： Lee DS,Kwak YK,Jeong SM,Song JH,Kang YN,Lee SN,Jang HS,Kim YS,Yoon SC,Choi BO

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:The prognosis of breast cancer-derived brain metastasis is poor, but new drugs and recent therapeutic strategies have helped extend survival in patients. Prediction of therapeutic responses and outcomes is not yet possible, however. In a retrospective study, we examined prognostic factors in patients with bre...

journal_title：Japanese journal of clinical oncology

authors： Honda Y,Aruga T,Yamashita T,Miyamoto H,Horiguchi K,Kitagawa D,Idera N,Goto R,Kuroi K

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:We carried out the present study to investigate the feasibility and effectiveness of concurrent chemoradiotherapy (CT-RT) for postoperative recurrent esophageal cancer, which are, at present, unclear. METHODS:Between 1998 and 2002, 16 patients with postoperative loco-regional recurrence of esophageal cancer...

journal_title：Japanese journal of clinical oncology

authors： Nishimura Y,Koike R,Nakamatsu K,Kanamori S,Suzuki M,Shigeoka H,Shiozaki H

更新日期：2003-07-01 00:00:00

abstract：:Peripheral plasma prostaglandins (PGs) were assayed in 10 cases of gynecologic malignancies. In addition, fluctuations of PG levels during chemotherapeutically-induced gastrointestinal toxicity as well as those caused by a bolus infusion of steroid hormone were investigated. As a result, the level of PGE2 in most case...

journal_title：Japanese journal of clinical oncology

authors： Suzuki M,Ohwada M,Tamada T

更新日期：1987-09-01 00:00:00

abstract：Background:Few studies have simultaneously collected quantitative data regarding the positive and negative effects of participating in post-bereavement surveys. Methods:We conducted a cross-sectional postal questionnaire survey in October 2013. Potential participants were caregivers for family members who had died in ...

journal_title：Japanese journal of clinical oncology

authors： Miyashita M,Aoyama M,Yoshida S,Yamada Y,Abe M,Yanagihara K,Shirado A,Shutoh M,Okamoto Y,Hamano J,Miyamoto A,Nakahata M

更新日期：2018-02-01 00:00:00

abstract：:In the present nationwide survey, 1,040 new cases of lymphoid malignancy, in most of which expression of cell surface markers had been determined, and 243 controls for a case-control study on adult T-cell leukemia/lymphoma (ATL) and other types of lymphoid malignancies were enrolled during the two years (1982-84) from...

journal_title：Japanese journal of clinical oncology

authors：

更新日期：1985-09-01 00:00:00

abstract：:Primary mesenteric liposarcoma is a rare entity that has been reported only 14 times in English literature. The treatment strategy for mesenteric liposarcoma is, if no distant metastases are detected, surgical resection with a wide surgical margin, often followed by radiation and/or adjuvant chemotherapy for high-risk...

journal_title：Japanese journal of clinical oncology

authors： Ishiguro S,Yamamoto S,Chuman H,Moriya Y

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:To clarify the association between pre-treatment total bilirubin (PTB) level and severe toxicity in patients receiving cisplatin and irinotecan. METHODS:We analyzed retrospectively the relationships of grade 4 neutropenia or grade 3-4 diarrhea and clinical variables including PTB and pre-treatment neutrophil...

journal_title：Japanese journal of clinical oncology

authors： Fujiwara Y,Sekine I,Ohe Y,Kunitoh H,Yamamoto N,Nokihara H,Simmyo Y,Fukui T,Yamada K,Tamura T

更新日期：2007-05-01 00:00:00

abstract：:Myoepithelioma is a rare neoplasm usually occurring in the salivary glands or the mammary glands but also, more rarely, in the thoracic cavity. The diagnosis of myoepithelioma is based on the presence of histological and immunohistochemical characteristics of myoepithelioma, but in unusual locations, the diagnosis is ...

journal_title：Japanese journal of clinical oncology

authors： Habu T,Soh J,Toji T,Shien K,Niman E,Namba K,Sato H,Yamamoto H,Sugimoto S,Yamane M,Toyooka S

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Patients suffering from hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT) generally have a poor prognosis. We therefore conducted a prospective pilot trial of combined transcatheter arterial chemoembolization (TACE) and local radiotherapy (RT) for PVTT in unresectable HCC. The aim of the ...

journal_title：Japanese journal of clinical oncology

authors： Yamada K,Soejima T,Sugimoto K,Mayahara H,Izaki K,Sasaki R,Maruta T,Matsumoto S,Hirota S,Sugimura K

更新日期：2001-04-01 00:00:00