High-dose radiotherapy using helical tomotherapy for vertebral metastasis: early clinical outcomes and cord dose specification.

abstract：:The joint international symposium of the 22nd Hiroshima Cancer Seminar and the 4th Japanese Association for RNA Interference focused on a pivotal role of microRNAs in carcinogenesis, progression and therapy of human cancer. Mammalian immune regulator MCPIP1 (Zc3h12a) RNase acts as a novel suppressor of microRNA activi...

journal_title：Japanese journal of clinical oncology

authors： Tahara H,Kay MA,Yasui W,Tahara E

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:We sought to investigate general health status and late effects among adolescent and young adult survivors of childhood cancer. METHODS:We conducted a cross-sectional survey, using self-rated questionnaires on current and past health problems. Questionnaires were provided to childhood cancer survivors, a com...

journal_title：Japanese journal of clinical oncology

authors： Ozono S,Ishida Y,Honda M,Okamura J,Asami K,Maeda N,Sakamoto N,Inada H,Iwai T,Kamibeppu K,Kakee N,Horibe K

更新日期：2014-10-01 00:00:00

abstract：Background:Gene associated with retinoid-interferon induced mortality-19 (GRIM-19) plays crucial roles in carcinogenesis. Objective:To explore the antitumor activity of internalizing NGR (iNGR) gene associated with GRIM-19 in colorectal cancer. Methods:Cells were incubated with fluorescein isothiocyanate-labeled fusi...

journal_title：Japanese journal of clinical oncology

authors： Pang L,Xia Y,Wang D,Meng X

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:It has been reported that prognosis is less favorable in poorly (G3) differentiated endometrioid adenocarcinoma than in well (G1) or moderately (G2) differentiated endometrioid adenocarcinoma. The goal of this study is therefore to analyze the prognosis of G3 endometrioid adenocarcinoma and various factors t...

journal_title：Japanese journal of clinical oncology

authors： Kuwabara Y,Susumu N,Banno K,Hirao T,Kawaguchi M,Yamagami W,Suzuki N,Aoki D,Nozawa S

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:Studies have suggested that bevacizumab has shown activity against various pediatric solid tumors. We, therefore, conducted a Phase I study of bevacizumab plus irinotecan in Japanese children with recurrent, progressive or refractory solid tumors. METHODS:The starting dose was bevacizumab 10 mg/kg over 60-90...

journal_title：Japanese journal of clinical oncology

authors： Okada K,Yamasaki K,Tanaka C,Fujisaki H,Osugi Y,Hara J

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:The importance of quality assurance in cancer screening has recently gained increasing attention in Japan. To evaluate and improve quality, checklists and process indicators have been developed. To explore effective methods of enhancing quality in cancer screening, we started a randomized control study of the...

journal_title：Japanese journal of clinical oncology

authors： Machii R,Saika K,Higashi T,Aoki A,Hamashima C,Saito H

更新日期：2012-02-01 00:00:00

abstract：:Pure red cell aplasia (PRCA) rarely occurs in non-thymic lymphoproliferative disorders. The present article describes a patient with non-Hodgkin's lymphoma (follicular, mixed type), who concurrently developed PRCA and warm type autoimmune hemolytic anemia during the clinical course. The PRCA and hemolytic anemia were ...

journal_title：Japanese journal of clinical oncology

authors： Suzuki A,Takahashi T,Taniguchi A,Kotake C,Seo T,Toda T,Kobayashi K,Tsukamoto N,Fukumoto M

更新日期：1991-10-01 00:00:00

abstract：:Previous studies have demonstrated the monoclonal antibody, TFS-4, to recognize a cell surface antigen, 124,000 Daltons, of molecular weight expressed selectively on small cell lung cancer but not on non-small cell lung cancer, and to cross-react with the human brain, cardiac muscle and some smooth muscle cells. The c...

journal_title：Japanese journal of clinical oncology

authors： Umezawa Y,Kuge S,Kikyo N,Shirai T,Watanabe J,Fugisawa M,Okabe T

更新日期：1991-08-01 00:00:00

abstract：:Although malignant lymphoma of the breast is a rare disease, we recently experienced a high incidence of central nervous system (CNS) involvement. Thus, we retrospectively reviewed clinical records of 921 patients with breast tumors, treated from 1990 to 2002, to examine CNS involvement. Eight patients were found to h...

journal_title：Japanese journal of clinical oncology

authors： Yamazaki H,Hanada M,Kitada M,Kuyama J,Sato T,Nishikubo M,Ishida T,Inoue T,Inoue T

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVE:There have been no previous studies about consultation of the bereaved who have lost a loved one to cancer and ask for medical help. The aim of this study was to investigate their basic characteristics and their psychiatric disorders. METHODS:A retrospective study using clinical and background data obtained ...

journal_title：Japanese journal of clinical oncology

authors： Ishida M,Onishi H,Wada M,Tada Y,Ito H,Narabayashi M,Sasaki Y,Nomura S,Uchitomi Y

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:The treatment modality for desmoid-type fibromatosis has shifted from surgery to conservative treatment. This systematic review aims to evaluate the efficacy of low-dose chemotherapy with methotrexate and vinblastine for patients with extra-abdominal desmoid-type fibromatosis. METHODS:We searched the pertine...

journal_title：Japanese journal of clinical oncology

authors： Shimizu K,Hamada S,Sakai T,Koike H,Yoshida M,Nishida Y

更新日期：2020-04-07 00:00:00

abstract：OBJECTIVE:To investigate the prognostic value of interleukin-11 receptor α chain in patients with early-stage clear-cell renal cell carcinoma. Interleukin-11 receptor α chain, a member of the gp130-dependent receptors, exerts pleiotropic oncogenic activities by promoting proliferation, angiogenesis and metastasis in ma...

journal_title：Japanese journal of clinical oncology

authors： Pan D,Xu L,Liu H,Zhang W,Zhu Y,Xu J,Gu J

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:The optimal treatment for elderly patients with limited-disease small cell lung cancer has not been defined. We therefore performed a Phase I study for split-dose cisplatin plus etoposide combined with early concurrent accelerated hyperfractionated thoracic radiotherapy in elderly (70 years of age or older) p...

journal_title：Japanese journal of clinical oncology

authors： Okamoto K,Okamoto I,Takeda M,Kobayashi S,Takeda K,Nakamatsu K,Nishimura Y,Nakagawa K

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Vital dye-guided sentinel node biopsy is affordable in most hospitals, but may be of limited accuracy in identifying all sentinel nodes. Leaving sentinel nodes in the axilla may result in a false nodal staging of breast carcinomas. METHODS:From a series of 112 successful sentinel lymph node biopsies with Pa...

journal_title：Japanese journal of clinical oncology

authors： Cserni G,Rajtár M,Boross G

更新日期：2000-06-01 00:00:00

abstract：OBJECTIVE:The prognosis of breast cancer-derived brain metastasis is poor, but new drugs and recent therapeutic strategies have helped extend survival in patients. Prediction of therapeutic responses and outcomes is not yet possible, however. In a retrospective study, we examined prognostic factors in patients with bre...

journal_title：Japanese journal of clinical oncology

authors： Honda Y,Aruga T,Yamashita T,Miyamoto H,Horiguchi K,Kitagawa D,Idera N,Goto R,Kuroi K

更新日期：2015-08-01 00:00:00

abstract：:In conclusion, a review of the epidemiology and pathology of latent prostatic cancer suggests this tumor to be the probable initial phase of a biological continuum that ends with metastatic cancer. Histological grade and tumor volume are highly correlated, as are histological grade and mitotic index. It has also been ...

journal_title：Japanese journal of clinical oncology

authors： Yatani R,Kusano I,Shiraishi T,Hayashi T,Stemmermann GN

更新日期：1989-12-01 00:00:00

abstract：:Head and neck cancer is a major cause of morbidity and mortality in Hong Kong. HNC is well-known for its heterogeneity in epidemiology, clinical behavior, clinic-pathological features and patient characteristics. Treatment strategies for this heterogeneous disease vary greatly in different parts of the world, dependin...

journal_title：Japanese journal of clinical oncology

authors： Ng WT,Wong ECY,Lee VHF,Chan JYW,Lee AWM

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:The cell cycle profile test is suggested to be an independent prognostic indicator for breast cancer patients. To further clarify the prognostic value, we applied this to breast cancer patients treated with postoperative 5-fluorouracil-based chemotherapy. METHODS:A total of 153 breast cancer patients, who we...

journal_title：Japanese journal of clinical oncology

authors： Kurebayashi J,Kanomata N,Kozuka Y,Moriya T,Kikukawa N,Kawasaki Y,Harada S,Tamura S,Nakayama S,Ishihara H,Noguchi S,Sonoo H

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:A combination of cisplatin and vinorelbine chemotherapy is effective in cases of advanced non-small cell lung cancer, but the optimum administration schedule for both drugs has not yet been defined. The aim of this study was to determine the maximum dose of vinorelbine that can be tolerated while receiving a...

journal_title：Japanese journal of clinical oncology

authors： Hotta K,Sekine I,Tamura T,Sawada M,Watanabe H,Kusaba H,Akiyama Y,Inoue A,Shimoyama T,Nokihara H,Ueda Y,Yamamoto N,Kunitoh H,Ohe Y,Kodama T,Saijo N

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVE:To identify predictors of biochemical recurrence (BCR) after radical prostatectomy with or without standard pelvic lymphadenectomy in Korean men with high-risk prostate cancer. METHODS:The clinical and pathologic data of 199 patients with high-risk features were reviewed retrospectively. High-risk features w...

journal_title：Japanese journal of clinical oncology

authors： Ku JH,Jeong CW,Park YH,Cho MC,Kwak C,Kim HH

更新日期：2011-05-01 00:00:00

abstract：:Although it has been reported that the risk of second malignancies increases in long-term survivors of small cell lung cancer (SCLC) and late recurrence of SCLC is sometimes experienced, it seems uncommon. We recently experienced a case of redevelopment of SCLC after a long disease-free period. The case was considered...

journal_title：Japanese journal of clinical oncology

authors： Kitamoto Y,Hayakawa K,Mitsuhashi N,Tsuchiya S,Saito R

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Inconsistency in the prevalence of infection by human papillomavirus (HPV) in lung cancer patients was found between different countries with racial and geographic variations. Our previous reports have indicated that a high-risk HPV 16/18 DNA was frequently detected in Chinese lung cancer patients living in ...

journal_title：Japanese journal of clinical oncology

authors： Fei Y,Yang J,Hsieh WC,Wu JY,Wu TC,Goan YG,Lee H,Cheng YW

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:In a tumor, increased deubiquitination of cyclins by a protein gene product gene, PGP9.5, could contribute to the uncontrolled growth of somatic cells that is a hallmark of cancer. We hypothesized that PGP9.5 may be expressed in tumors of patients with non-small cell lung cancer (NSCLC). METHODS:Expression ...

journal_title：Japanese journal of clinical oncology

authors： Sasaki H,Yukiue H,Moriyama S,Kobayashi Y,Nakashima Y,Kaji M,Fukai I,Kiriyama M,Yamakawa Y,Fujii Y

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Cytokeratins (CKs) 19 and 20 have been used as targets for detecting cancer cells. We attempted to detect circulating cancer cells in patients with gastric cancer using a high-sensitivity reverse transcriptase-polymerase chain reaction (RT-PCR) assay for CK transcripts. METHODS:RT-PCR for CK 19 and CK 20 wa...

journal_title：Japanese journal of clinical oncology

authors： Majima T,Ichikura T,Takayama E,Chochi K,Mochizuki H

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:One of the most studied pro-angiogenic factors involved in the development of colorectal cancer is the vascular endothelial growth factor (VEGF). The small molecule tyrosine kinase inhibitor semaxanib (SU5416) is one of the several agents targeting the VEGF signaling pathway, and its development centered mos...

journal_title：Japanese journal of clinical oncology

authors： Hoff PM,Wolff RA,Bogaard K,Waldrum S,Abbruzzese JL

更新日期：2006-02-01 00:00:00

abstract：:MVP-CAB chemotherapy (methotrexate, vincristine, cisplatin, cyclophosphamide, adriamycin and bleomycin) was administered to 28 patients with high grade, locally-invasive or regional lymph node-involved urothelial cancer as an adjuvant therapy after radical surgery. The median follow-up period of all the evaluated pati...

journal_title：Japanese journal of clinical oncology

authors： Gohji K,Higuchi A,Maruyama S,Minayoshi K,Fujii A,Itoh N,Hasunuma Y,Tanaka H,Izumi T

更新日期：1993-10-01 00:00:00

abstract：Background:Gliomas are highly malignant brain tumors. Aberrant activation of NF-κB plays a crucial role in tumor progression. Method:ELISA assay was used to detect NF-κB activity in glimoas cells with different treatments. PPP3CC expression was evaluated by qRT-PCR and western blot assay. Kaplan-Meier analysis estimat...

journal_title：Japanese journal of clinical oncology

authors： Wang H,Zhao S,Chen B,Fu C,Dang Y,Fang P,Wang J,Wang N,Liu L

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Intensity-modulated radiotherapy (IMRT) using the simultaneous integrated boost (SIB) method was designed for treating malignant gliomas. The purpose of this study was to investigate feasibility of this treatment. METHODS:Between December 2000 and November 2002, six patients with malignant gliomas were enro...

journal_title：Japanese journal of clinical oncology

authors： Suzuki M,Nakamatsu K,Kanamori S,Okumra M,Uchiyama T,Akai F,Nishimura Y

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:In Japan, concurrent chemoradiotherapy is the standard treatment for unresectable esophageal cancer. The optimal combination of chemotherapeutic agents and radiotherapy dose remains controversial. The present study consists of a phase II trial of a cisplatin (CDDP)/5-fluorouracil (5-FU) infusion with concurr...

journal_title：Japanese journal of clinical oncology

authors： Ishida K,Ando N,Yamamoto S,Ide H,Shinoda M

更新日期：2004-10-01 00:00:00

abstract：:The Japan Public Health Center-based prospective Study conducted a baseline survey for 140 000 registered residents aged 40-69 years within 11 public health center areas nationwide in 1990-94. Five- and 10-year follow-up surveys were conducted to update information on lifestyle habits and health conditions. In total, ...

journal_title：Japanese journal of clinical oncology

authors： Tsugane S,Sawada N

更新日期：2014-09-01 00:00:00