The JPHC study: design and some findings on the typical Japanese diet.

abstract：:Human lymphoblastoid interferon-alpha was administered intramuscularly at a dose of 5 x 10(6) units/day to 20 metastatic renal cell carcinoma patients. For potentiating the antitumor effect of interferon, cimetidine was also given to them orally at a dose of 800 mg/day. The combination therapy obtained a complete resp...

journal_title：Japanese journal of clinical oncology

authors： Kotake T,Kinouchi T,Saiki S,Kuroda M,Miki T,Kiyohara H,Usami M

更新日期：1991-02-01 00:00:00

abstract：:The patient was a 9-year-old premenarcheal pediatric female, whose chief complaint was a well-circumscribed palpable right breast mass without nipple discharge. Although the patient had noticed the lump 2 years prior to hospital admission, its size (1.5 × 1.3 cm) had been stable. There was no family history or previou...

journal_title：Japanese journal of clinical oncology

authors： Yorozuya K,Takahashi E,Kousaka J,Mouri Y,Yoshida M,Fujii K,Akizuki M,Nakano S,Fukutomi T,Umemoto Y,Yokoi T,Imai H

更新日期：2012-03-01 00:00:00

abstract：:We present a case of pancreatic leiomyosarcoma with liver metastasis diagnosed by liver tumor biopsy. A 66-year-old man had a pancreatic tumor and hepatic tumors, which were hypoechoic and mixed echoic on ultrasonography, respectively. They were stained in enhanced computed tomography and angiography. A fine needle as...

journal_title：Japanese journal of clinical oncology

authors： Ishii H,Okada S,Okazaki N,Nose H,Yoshimori M,Aoki K,Tsuda H,Hirohashi S

更新日期：1994-02-01 00:00:00

abstract：OBJECTIVE:The treatment modality for desmoid-type fibromatosis has shifted from surgery to conservative treatment. This systematic review aims to evaluate the efficacy of low-dose chemotherapy with methotrexate and vinblastine for patients with extra-abdominal desmoid-type fibromatosis. METHODS:We searched the pertine...

journal_title：Japanese journal of clinical oncology

authors： Shimizu K,Hamada S,Sakai T,Koike H,Yoshida M,Nishida Y

更新日期：2020-04-07 00:00:00

abstract：:Recent time trends (1979-1987) and geographical distributions in mortalities from subsites of cancers of the hepato-biliary-pancreatic system have been investigated on the basis of the vital statistics of Japan. The corrected age-adjusted mortality rates (CAAMRs) were calculated to eliminate the influence of the propo...

journal_title：Japanese journal of clinical oncology

authors： Kato I,Kuroishi T,Tominaga S

更新日期：1990-09-01 00:00:00

abstract：:Head and neck cancer is a major cause of morbidity and mortality in Hong Kong. HNC is well-known for its heterogeneity in epidemiology, clinical behavior, clinic-pathological features and patient characteristics. Treatment strategies for this heterogeneous disease vary greatly in different parts of the world, dependin...

journal_title：Japanese journal of clinical oncology

authors： Ng WT,Wong ECY,Lee VHF,Chan JYW,Lee AWM

更新日期：2018-01-01 00:00:00

abstract：:Age-adjusted incidence rates for malignant lymphomas in eastern Asian countries except for the Kyushu district of Japan are lower than those in northern European, North and South American and Oceanian countries. Particularly, the incidence rates for Hodgkin's disease and follicular lymphoma are remarkably low in easte...

journal_title：Japanese journal of clinical oncology

authors： Tajima K,Tominaga S,Suchi T

更新日期：1983-09-01 00:00:00

abstract：:Thirteen postmortem examinations on neuroblastoma patients were reviewed clinicopathologically. Commonly found metastatic sites were bone, liver and lung. The introduction of massive doses of cyclophosphamide and cisplatinum into chemotherapy protocol markedly reduced the tumor burden: no tumor focus in liver or lung,...

journal_title：Japanese journal of clinical oncology

authors： Naito H,Sasaki M,Takeda T,Nakadate H,Fujita M

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND:Colorectal cancer is one of the most common carcinomas observed in humans. Recently we have reported that increased oxidative stress is associated with human colorectal cancer. There are few and controversial studies on the clinical relevance of the expression of heat shock protein 70 (HSP 70), a member of t...

journal_title：Japanese journal of clinical oncology

authors： Ozdemirler Erata G,Kanbağli O,Durlanik O,Bulut T,Toker G,Uysal M

更新日期：2005-02-01 00:00:00

abstract：:AMG 337, a selective small-molecule MET inhibitor, was evaluated in Asian patients with advanced solid tumors. Eligible patients orally self-administered AMG 337; the initial dose of 150 mg once daily (QD) was escalated to 300 mg QD (modified 3+3+3 design). Treatment continued until disease progression, intolerability...

journal_title：Japanese journal of clinical oncology

authors： Yasui H,Go N,Yang H,Amore BM,Jung AS,Doi T

更新日期：2017-08-01 00:00:00

abstract：:A prospective multicenter trial has been started in Korea to investigate the treatment efficacy of a levonorgestrel-releasing intrauterine system plus medroxyprogesterone acetate in young women with early-stage endometrial cancer. A number of studies have reported the effectiveness of hormonal therapy using systemic p...

journal_title：Japanese journal of clinical oncology

authors： Kim MK,Seong SJ,Lee TS,Kim JW,Nam BH,Hong SR,Suh KS

更新日期：2012-12-01 00:00:00

abstract：:Squamous cell carcinoma of the head and neck is characterized by an immunosuppressive environment and evades immune responses through multiple resistance mechanisms. A breakthrough in cancer immunotherapy employing immune checkpoint inhibitors has evolved into a number of clinical trials with antibodies against progra...

journal_title：Japanese journal of clinical oncology

authors： Yokota T,Homma A,Kiyota N,Tahara M,Hanai N,Asakage T,Matsuura K,Ogawa T,Saito Y,Sano D,Kodaira T,Motegi A,Yasuda K,Takahashi S,Tanaka K,Onoe T,Okano S,Imamura Y,Ariizumi Y,Hayashi R,Japan Clinical Oncology Group (

更新日期：2020-09-28 00:00:00

abstract：:The continuous intravenous administration of 1-(2-tetrahydrofuryl)-5-fluorouracil (FT) to colorectal cancer patients was studied in regard to the stability of FT in intravenous hyperalimentation (IVH) solutions and tumor levels of 5-fluorouracil (5-FU). FT was very compatible with IVH solutions, because the decomposit...

journal_title：Japanese journal of clinical oncology

authors： Moriya Y,Koyama Y,Hojo K,Tsunematsu R

更新日期：1983-03-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to detect the presence of cancer stem-like cells with bronchioalveolar stem cells (BASCs) properties and investigate the clinicopathological role of expression of OCT4 as well as the correlation with clinical outcomes in adenocarcinoma of the lung. METHODS:Specimens of 112 cases...

journal_title：Japanese journal of clinical oncology

authors： Zhang X,Han B,Huang J,Zheng B,Geng Q,Aziz F,Dong Q

更新日期：2010-10-01 00:00:00

abstract：:Alendronate, a bisphosphonate compound, lowers serum calcium in patients with cancer-associated hypercalcemia through its inhibitory effect on bone resorption and as a result symptoms associated with hypercalcemia improve. This study was carried out to investigate the effects of alendronate in patients with hypercalce...

journal_title：Japanese journal of clinical oncology

authors： Ohnishi T,Takeda E,Yogita S,Miyake H,Kinoshita T,Terashima Y,Matsumoto T,Tashiro S

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:A self-administered quantitative food frequency questionnaire (Qx) was developed for a population-based cohort study on cancer in Takayama, Japan. METHODS:The Qx was tested among 58 male and 59 female volunteers. Average daily nutrient intakes for the previous year calculated from the Qx were compared with ...

journal_title：Japanese journal of clinical oncology

authors： Shimizu H,Ohwaki A,Kurisu Y,Takatsuka N,Ido M,Kawakami N,Nagata C,Inaba S

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:To determine the maximum tolerated dose and recommended dose of cisplatin and docetaxel administered by three consecutive weekly infusions in both non-elderly (< or =74 years) and elderly (> or =75 years) patients, we conducted two independent phase I studies for nonelderly and elderly patients with non-smal...

journal_title：Japanese journal of clinical oncology

authors： Ohe Y,Niho S,Kakinuma R,Kubota K,Matsumoto T,Ohmatsu H,Goto K,Kunitoh H,Saijo N,Nishiwaki Y

更新日期：2001-03-01 00:00:00

abstract：:MVP-CAB chemotherapy (methotrexate, vincristine, cisplatin, cyclophosphamide, adriamycin and bleomycin) was administered to 28 patients with high grade, locally-invasive or regional lymph node-involved urothelial cancer as an adjuvant therapy after radical surgery. The median follow-up period of all the evaluated pati...

journal_title：Japanese journal of clinical oncology

authors： Gohji K,Higuchi A,Maruyama S,Minayoshi K,Fujii A,Itoh N,Hasunuma Y,Tanaka H,Izumi T

更新日期：1993-10-01 00:00:00

abstract：OBJECTIVE:To investigate practical patterns for stereotactic body radiotherapy to hepatocellular carcinoma in Korea. METHODS:In June 2013, the Korean Stereotactic Radiosurgery Group of the Korean Society for Radiation Oncology conducted a national patterns-of-care survey about stereotactic body radiotherapy to the liv...

journal_title：Japanese journal of clinical oncology

authors： Bae SH,Kim MS,Jang WI,Kay CS,Kim W,Kim ES,Kim JH,Kim JH,Yang KM,Lee KC,Chang AR,Jo S

更新日期：2016-04-01 00:00:00

abstract：:Mucin-producing carcinoma of the thyroid is rare and its histogenesis has been debated. The first case was reported by Diaz-Perez et al. (1976). We herein report the sixth case of mucin-producing carcinoma of the thyroid which was discovered in a 72-year-old Japanese woman. This patient was admitted with a 10-year his...

journal_title：Japanese journal of clinical oncology

authors： Harada T,Shimaoka K,Hiratsuka M,Hirokawa M,Tsukayama C

更新日期：1984-09-01 00:00:00

abstract：PURPOSE:Breast cancers in the early phase frequently undergo distant metastasis and survival of patients is greatly dependent on distant metastasis. The occurrence of micrometastasis has been suggested to relate with prognostic features of breast cancer, such as lymph node metastasis and the presence of vascular invasi...

journal_title：Japanese journal of clinical oncology

authors： Jung YS,Lee KJ,Kim HJ,Yim HE,Park JS,Soh EY,Kim MW,Park HB

更新日期：2003-04-01 00:00:00

abstract：Background:Few studies have simultaneously collected quantitative data regarding the positive and negative effects of participating in post-bereavement surveys. Methods:We conducted a cross-sectional postal questionnaire survey in October 2013. Potential participants were caregivers for family members who had died in ...

journal_title：Japanese journal of clinical oncology

authors： Miyashita M,Aoyama M,Yoshida S,Yamada Y,Abe M,Yanagihara K,Shirado A,Shutoh M,Okamoto Y,Hamano J,Miyamoto A,Nakahata M

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:The optimal management of elderly patients with limited-disease small cell lung cancer (LD-SCLC) has not been established. METHODS:The records of elderly (>or=70 years of age) patients with LD-SCLC who had been treated with etoposide and cisplatin chemotherapy with early concurrent twice-daily thoracic radio...

journal_title：Japanese journal of clinical oncology

authors： Okamoto K,Okamoto I,Takezawa K,Tachibana I,Fukuoka M,Nishimura Y,Nakagawa K

更新日期：2010-01-01 00:00:00

abstract：:A Phase II study was started in Japan to evaluate the efficacy and safety of concurrent chemoradiotherapy with S-1 plus cisplatin in patients with unresectable locally advanced squamous cell carcinoma of the head and neck. This study began in July 2008, and a total of 45 patients will be accrued from 13 institutions w...

journal_title：Japanese journal of clinical oncology

authors： Nakamura K,Tahara M,Kiyota N,Hayashi R,Akimoto T,Fukuda H,Fujii M,Boku N

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Combination of bleomycin, etoposide and cisplatin (BEP) remains the standard chemotherapy for testicular cancer. Since the development of BEP in the 1980s, there has been a considerable advance in supportive therapies, such as granulocyte colony-stimulating-factor and 5-HT3 antagonists. Therefore, we re-eval...

journal_title：Japanese journal of clinical oncology

authors： Kawai K,Ando S,Hinotsu S,Oikawa T,Sekido N,Miyanaga N,Shimazui T,Akaza H

更新日期：2006-07-01 00:00:00

abstract：:The relations between alcohol consumption and cancers of the breast, corpus uteri and ovary were investigated in a case-control study involving 1,740 cases of breast cancer, 239 cases of cancer of the corpus uteri, 417 cases of ovarian cancer and 8,920 controls with other cancer sites identified from the Aichi Cancer ...

journal_title：Japanese journal of clinical oncology

authors： Kato I,Tominaga S,Terao C

更新日期：1989-09-01 00:00:00

abstract：:Some cancer patients suddenly develop severe, excruciating pain that requires rapid management using opioid medication. This study aimed to evaluate the effectiveness of rapid titration using oxycodone injection. Study subjects were advanced cancer patients who experienced severe pain (numeric rating scale ≥7) and nee...

journal_title：Japanese journal of clinical oncology

authors： Nakajima N

更新日期：2019-12-18 00:00:00

abstract：BACKGROUND:In Japan, concurrent chemoradiotherapy is the standard treatment for unresectable esophageal cancer. The optimal combination of chemotherapeutic agents and radiotherapy dose remains controversial. The present study consists of a phase II trial of a cisplatin (CDDP)/5-fluorouracil (5-FU) infusion with concurr...

journal_title：Japanese journal of clinical oncology

authors： Ishida K,Ando N,Yamamoto S,Ide H,Shinoda M

更新日期：2004-10-01 00:00:00

abstract：:A 50-year-old man underwent a left nephrectomy for renal cell carcinoma of the clear cell type in February, 1978. He was examined using computed tomography in September, 1993, and was found to have a small coin lesion in his right lung. A fine needle aspiration biopsy failed to disclose any tumor cells. He underwent a...

journal_title：Japanese journal of clinical oncology

authors： Yoshida J,Nagai K,Hasebe T,Takahashi K,Nishimura M,Otsuka S,Nishiwaki Y,Kodama T

更新日期：1995-02-01 00:00:00

abstract：:A 56-year-old man, tentatively diagnosed as having cardiomegaly, was found to have a large cyst in the left anterior mediastinum. At thoracotomy a multilocular cystic mass containing a colorless serous fluid was found and resected. Histologically, the cyst was lined with flattened epithelial cells, and thymic tissue w...

journal_title：Japanese journal of clinical oncology

authors： Sano T,Kuramochi S,Takahashi M,Asanuma F,Yamada Y,Uesato K,Toyoda H,Miyagawa T,Kurokawa T,Kawamura E

更新日期：1991-10-01 00:00:00