Triple carcinomas in Cronkhite-Canada syndrome.

abstract：BACKGROUND:Combination of bleomycin, etoposide and cisplatin (BEP) remains the standard chemotherapy for testicular cancer. Since the development of BEP in the 1980s, there has been a considerable advance in supportive therapies, such as granulocyte colony-stimulating-factor and 5-HT3 antagonists. Therefore, we re-eval...

journal_title：Japanese journal of clinical oncology

authors： Kawai K,Ando S,Hinotsu S,Oikawa T,Sekido N,Miyanaga N,Shimazui T,Akaza H

更新日期：2006-07-01 00:00:00

abstract：:A randomized Phase II/III trial commenced in Japan in December 2013. Carboplatin plus etoposide is the current standard treatment for elderly extensive-disease small-cell lung cancer. The purpose of this study is to confirm the superiority of carboplatin plus irinotecan in terms of overall survival over carboplatin pl...

journal_title：Japanese journal of clinical oncology

authors： Eba J,Shimokawa T,Nakamura K,Shibata T,Misumi Y,Okamoto H,Yamamoto N,Ohe Y,Lung Cancer Study Group of the Japan Clinical Oncology Group.

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Elastography is a technique for detecting the stiffness of tissues. We applied elastography for the diagnosis of prostate cancer and evaluated the usefulness of elastography for prostate biopsy. METHODS:The subjects of this study were 311 patients who underwent elastography during prostate needle biopsy at H...

journal_title：Japanese journal of clinical oncology

authors： Miyagawa T,Tsutsumi M,Matsumura T,Kawazoe N,Ishikawa S,Shimokama T,Miyanaga N,Akaza H

更新日期：2009-06-01 00:00:00

abstract：:Recent studies have suggested that glutathione S-transferase pi (GST-pi) may play a role in determining tumor sensitivities to cytotoxic drugs. In order to better understand the role of this enzyme in chemo- and/or radioresistance of lung cancer cells, we examined whether introduction of GST-pi cDNA into a chemo- and ...

journal_title：Japanese journal of clinical oncology

authors： Miyara H,Hida T,Nishida K,Takahashi T,Sugiura T,Ariyoshi Y,Morishita M,Takahashi T,Ueda R

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to detect the presence of cancer stem-like cells with bronchioalveolar stem cells (BASCs) properties and investigate the clinicopathological role of expression of OCT4 as well as the correlation with clinical outcomes in adenocarcinoma of the lung. METHODS:Specimens of 112 cases...

journal_title：Japanese journal of clinical oncology

authors： Zhang X,Han B,Huang J,Zheng B,Geng Q,Aziz F,Dong Q

更新日期：2010-10-01 00:00:00

abstract：:We found deletions of both alleles of the retinoblastoma gene (Rb) and the candidate Wilms' tumor gene (WT33) in a surgically resected human insulinoma by blot hybridization. Rearrangement of Krev-1, a transformation suppressor gene, was also detected in this case. The clinical and histological findings suggested that...

journal_title：Japanese journal of clinical oncology

authors： Iwamura Y,Futagawa T,Kaneko M,Nakagawa K,Kawai K,Yamashita K,Nakamura T,Hayashi H

更新日期：1992-02-01 00:00:00

abstract：Purpose:To investigate the usefulness of screening for patient symptoms as the fifth vital sign using an electronic medical recording system. Patients and methods:In the electronic medical recording system, all admitted patients received routine nurse-based assessment of discomfort (defined as any physical symptom) at...

journal_title：Japanese journal of clinical oncology

authors： Naito AS,Sakuma Y,Kinoshita H,Ito T,Mimatsu S,Tarumi A,Kiyohara E,Morita T

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:To investigate the prognostic value of interleukin-11 receptor α chain in patients with early-stage clear-cell renal cell carcinoma. Interleukin-11 receptor α chain, a member of the gp130-dependent receptors, exerts pleiotropic oncogenic activities by promoting proliferation, angiogenesis and metastasis in ma...

journal_title：Japanese journal of clinical oncology

authors： Pan D,Xu L,Liu H,Zhang W,Zhu Y,Xu J,Gu J

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:We evaluated whether color Doppler ultrasound (US) had diagnostic accuracy equal to dynamic computed tomography (CT) and whether performing dynamic CT and Doppler US together would be more informative in preoperative diagnosis of renal solid tumors. METHODS:A total of 110 renal solid tumors smaller than 7 c...

journal_title：Japanese journal of clinical oncology

authors： Kitamura H,Fujimoto H,Tobisu K,Mizuguchi Y,Maeda T,Matsuoka N,Komiyama M,Nakagawa T,Kakizoe T

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Although radiotherapy in combination with endocrinal manipulation has been identified as an effective treatment for patients with high-risk prostate cancer, the optimal dose for locoregional control of prostate cancer in combination with hormonal therapy has not yet been determined. METHODS:The efficacy of ...

journal_title：Japanese journal of clinical oncology

authors： Sasaki T,Nakamura K,Shioyama Y,Ohga S,Urashima Y,Terashima H,Koga H,Naito S,Noma H,Komatsu K,Yamaguchi A,Honda H

更新日期：2004-07-01 00:00:00

abstract：:Trousseau's syndrome (cancer-associated thrombosis) is the second leading cause of death in cancer patients, after death from cancer itself. The risk of a venous thromboembolism is 4- to 7-fold higher in patients with cancer than in those without cancer. The causes of this impaired coagulation are associated with gene...

journal_title：Japanese journal of clinical oncology

authors： Ikushima S,Ono R,Fukuda K,Sakayori M,Awano N,Kondo K

更新日期：2016-03-01 00:00:00

abstract：:Interleukin-12 (IL-12), known to be a strong inducer of interferon-gamma (IFN-gamma), plays a vital role in activating the immune surveillance system against intracellular pathogens and malignant tumors. The authors have found that cancer patients showing marked IFN-gamma induction after inoculation with BCG-CWS (the ...

journal_title：Japanese journal of clinical oncology

authors： Hayashi A,Noda A

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:CD10 is a cell surface metalloproteinase expressed by a variety of normal cell types, including lymphoid precursor cells, germinal center B lymphocytes and some epithelial cells. Although accumulating data indicate that CD10 expression by stromal cells is involved in colorectal carcinogenesis and it is a nov...

journal_title：Japanese journal of clinical oncology

authors： Huang WB,Zhou XJ,Chen JY,Zhang LH,Meng K,Ma HH,Lu ZF

更新日期：2005-05-01 00:00:00

abstract：:A 77-year-old man presented with painful swelling of his Port-A-Cath insertion site soon after flushing with normal saline. No discomfort or abnormality was found during the saline flush. A chest roentgenogram showed that the disconnected catheter had separated from the disc and was absent from its original location. ...

journal_title：Japanese journal of clinical oncology

authors： Lam AW,Chen YM,Yang KY,Tsai CM,Perng RP

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:It is common that patients with head and neck cancers have secondary malignant neoplasm of esophageal cancer. METHODS:To know the genetic background of the development of these secondary cancers, we performed microsatellite assay at six loci and immunohistochemical analysis on head and neck cancers of eight...

journal_title：Japanese journal of clinical oncology

authors： Kiriu H,Yokozaki H,Yasui W,Ito K,Tahara E

更新日期：1998-12-01 00:00:00

abstract：:This report describes a 78-year-old woman with insulinoma, treated with a combination of diphenylhydantoin and a calcium antagonist. The effectiveness of 200 mg of diphenylhydantoin and 180 mg of diltiazem was evaluated by measuring the levels of plasma glucose, immunoreactive insulin and immunoreactive insulin/plasma...

journal_title：Japanese journal of clinical oncology

authors： Imanaka S,Matsuda S,Ito K,Matsuoka T,Okada Y

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVE:The importance of quality assurance in cancer screening has recently gained increasing attention in Japan. To evaluate and improve quality, checklists and process indicators have been developed. To explore effective methods of enhancing quality in cancer screening, we started a randomized control study of the...

journal_title：Japanese journal of clinical oncology

authors： Machii R,Saika K,Higashi T,Aoki A,Hamashima C,Saito H

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:To report the results of radiotherapy for patients with failure, adverse reactions or relative contraindications to the use of steroids or immunosuppressants, by using newly developed quantitative indexes. METHODS:Fourteen female and six male patients with Graves' ophthalmopathy were treated with radiothera...

journal_title：Japanese journal of clinical oncology

authors： Sakata K,Hareyama M,Oouchi A,Shidou M,Nagakura H,Morita K,Osanai H,Ohtsuka K,Hinoda Y

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:Programmed death-ligand 1 is an immune modulator that promotes immunosuppression by binding to programmed death-1 of T-lymphocytes. Whereas programmed death-ligand 1 expression has been shown to be associated with the clinical response to anti-programmed death-ligand 1 antibody, the association of tumor prog...

journal_title：Japanese journal of clinical oncology

authors： Inamura K,Yokouchi Y,Sakakibara R,Kobayashi M,Subat S,Ninomiya H,Nagano H,Nomura K,Okumura S,Ishikawa Y

更新日期：2016-10-01 00:00:00

abstract：:Irinotecan chloride (CPT-11) is a new semi-synthetic camptothecin analogue which has encouraging antitumor activity against various malignancies. The major and unique toxicity of CPT-11 is diarrhea. Cardiovascular toxicity is rare and has not been found in clinical trials performed in Japan except for a very few cases...

journal_title：Japanese journal of clinical oncology

authors： Miya T,Fujikawa R,Fukushima J,Nogami H,Koshiishi Y,Goya T

更新日期：1998-11-01 00:00:00

abstract：:Five cases of recurrent cervical carcinoma with sites of recurrence restricted to the pelvis were treated by intra-arterial infusion of oncostatics via the bilateral internal iliac arteries. One tip of the catheter was positioned in the internal iliac artery, proximal and close to the superior glutea artery, through t...

journal_title：Japanese journal of clinical oncology

authors： Kawagoe K,Iijima S,Sasaki J

更新日期：1983-12-01 00:00:00

abstract：BACKGROUND:Adrenocortical carcinoma (ACC) is a rare tumor usually diagnosed at an advanced stage on invasion of or adherence to adjacent organs. We report surgical outcome of stage III and IV ACCs. METHODS:ACCs from seven patients at clinical stage II (n = 1), III (n = 4), or IV (n = 2) were resected. Combined resecti...

journal_title：Japanese journal of clinical oncology

authors： Ohwada S,Izumi M,Kawate S,Hamada K,Toya H,Togo N,Horiguchi J,Koibuchi Y,Takahashi T,Yamada M

更新日期：2007-02-01 00:00:00

abstract：:The occurrence of multiple primary cancers in the aerodigestive tract is a well known phenomenon that has been explained by the concept of 'field carcinogenesis'. Metachronous or synchronous esophageal cancer has usually been identified in patients with head and neck cancer, gastric cancer or colon cancer. The inciden...

journal_title：Japanese journal of clinical oncology

authors： Naomoto Y,Haisa M,Yamatsuji T,Shirakawa Y,Muramatsu T,Isozaki H,Kamikawa Y,Tanaka N

更新日期：1999-07-01 00:00:00

abstract：:The PRECIOUS study (UMIN000018202) is being conducted as a multicenter, randomized, open-label Phase III study to determine if retreatment with pertuzumab is more effective than conventional treatment in HER2-positive locally advanced (LA)/metastatic breast cancer (MBC) patients previously treated with pertuzumab, tra...

journal_title：Japanese journal of clinical oncology

authors： Yamamoto Y,Iwata H,Ueno T,Taira N,Kashiwaba M,Takahashi M,Tada H,Tsugawa K,Toyama T,Niikura N,Hara F,Fujisawa T,Yoshinami T,Saji S,Takano T,Masuda N,Morita S,Toi M,Ohno S

更新日期：2018-09-01 00:00:00

abstract：:The concepts of lifetime and age-conditional probabilities of developing and dying of cancer are introduced as indexes to understand the risk of cancer. In this paper, we estimated the lifetime and age-conditional probabilities of developing and dying of cancer in 2001 and 2005, respectively, in Japan. It is estimated...

journal_title：Japanese journal of clinical oncology

authors： Kamo K,Katanoda K,Matsuda T,Marugame T,Ajiki W,Sobue T

更新日期：2008-08-01 00:00:00

abstract：:There has been no previous report of oxaliplatin administration in patients undergoing hemodialysis. A 65-year-old female with end-stage renal disease who was undergoing hemodialysis presented with anemia in August 2005. She was diagnosed with colon cancer with multiple liver metastases. After colectomy, hepatic arter...

journal_title：Japanese journal of clinical oncology

authors： Shitara K,Munakata M,Muto O,Okada R,Mitobe S,Mino M,Ikami I,Sakata Y

更新日期：2007-07-01 00:00:00

abstract：:A case of multiple thymoma is reported. The patient was a 28-year-old woman who came to us with myasthenia gravis. There were two separate thymoma in the anterior mediastinum: one measured 70 x 30 x 30 mm, while the other was 1.5 mm in diameter and situated in the surrounding thymic tissue. A histological study reveal...

journal_title：Japanese journal of clinical oncology

authors： Nomori H,Kobayashi K,Ishihara T,Suito T,Torikata C

更新日期：1990-06-01 00:00:00

abstract：:Human lymphoblastoid interferon-alpha was administered intramuscularly at a dose of 5 x 10(6) units/day to 20 metastatic renal cell carcinoma patients. For potentiating the antitumor effect of interferon, cimetidine was also given to them orally at a dose of 800 mg/day. The combination therapy obtained a complete resp...

journal_title：Japanese journal of clinical oncology

authors： Kotake T,Kinouchi T,Saiki S,Kuroda M,Miki T,Kiyohara H,Usami M

更新日期：1991-02-01 00:00:00

abstract：:We report four cases of malignant melanoma of the esophagus treated at the National Cancer Center Hospital in Tokyo over a period of 28 years. There were three men and one woman. One patient had been diagnosed as having Werner's syndrome. The three male patients smoked and were alcohol drinkers. The chief complaint wa...

journal_title：Japanese journal of clinical oncology

authors： Kato H,Watanabe H,Tachimori Y,Watanabe H,Iizuka T,Yamaguchi H,Ishikawa T,Itabashi M

更新日期：1991-08-01 00:00:00

abstract：OBJECTIVE:To clarify the association between pre-treatment total bilirubin (PTB) level and severe toxicity in patients receiving cisplatin and irinotecan. METHODS:We analyzed retrospectively the relationships of grade 4 neutropenia or grade 3-4 diarrhea and clinical variables including PTB and pre-treatment neutrophil...

journal_title：Japanese journal of clinical oncology

authors： Fujiwara Y,Sekine I,Ohe Y,Kunitoh H,Yamamoto N,Nokihara H,Simmyo Y,Fukui T,Yamada K,Tamura T

更新日期：2007-05-01 00:00:00