Real-time elastography for the diagnosis of prostate cancer: evaluation of elastographic moving images.

abstract：OBJECTIVE:To clarify the association between pre-treatment total bilirubin (PTB) level and severe toxicity in patients receiving cisplatin and irinotecan. METHODS:We analyzed retrospectively the relationships of grade 4 neutropenia or grade 3-4 diarrhea and clinical variables including PTB and pre-treatment neutrophil...

journal_title：Japanese journal of clinical oncology

authors： Fujiwara Y,Sekine I,Ohe Y,Kunitoh H,Yamamoto N,Nokihara H,Simmyo Y,Fukui T,Yamada K,Tamura T

更新日期：2007-05-01 00:00:00

abstract：:In Japan, lateral lymph node dissection (LLND) is generally performed for the treatment of T3-4 lower rectal carcinoma, and not for T1 lower rectal carcinoma, because of a low positive rate in patients with T1 lesion. We experienced a rare case of lateral pelvic lymph node recurrence after total mesorectal resection f...

journal_title：Japanese journal of clinical oncology

authors： Hara J,Yamamoto S,Fujita S,Akasu T,Moriya Y

更新日期：2008-04-01 00:00:00

abstract：:The relations between alcohol consumption and cancers of the breast, corpus uteri and ovary were investigated in a case-control study involving 1,740 cases of breast cancer, 239 cases of cancer of the corpus uteri, 417 cases of ovarian cancer and 8,920 controls with other cancer sites identified from the Aichi Cancer ...

journal_title：Japanese journal of clinical oncology

authors： Kato I,Tominaga S,Terao C

更新日期：1989-09-01 00:00:00

abstract：:Interleukin-12 (IL-12), known to be a strong inducer of interferon-gamma (IFN-gamma), plays a vital role in activating the immune surveillance system against intracellular pathogens and malignant tumors. The authors have found that cancer patients showing marked IFN-gamma induction after inoculation with BCG-CWS (the ...

journal_title：Japanese journal of clinical oncology

authors： Hayashi A,Noda A

更新日期：1996-06-01 00:00:00

abstract：:Immunoperoxidase staining for human keratin proteins was performed cytologically on samples from 90 patients with malignant tumors, and histologically on samples from 164 patients with malignant tumors. At the cytological level, almost all tumor cells not only in squamous cell carcinoma but also in nonsquamous cell ca...

journal_title：Japanese journal of clinical oncology

authors： Yagi Y,Imamura Y,Saku T,Shimotsu T,Hatae M,Yagi S

更新日期：1986-03-01 00:00:00

abstract：:AMG 337, a selective small-molecule MET inhibitor, was evaluated in Asian patients with advanced solid tumors. Eligible patients orally self-administered AMG 337; the initial dose of 150 mg once daily (QD) was escalated to 300 mg QD (modified 3+3+3 design). Treatment continued until disease progression, intolerability...

journal_title：Japanese journal of clinical oncology

authors： Yasui H,Go N,Yang H,Amore BM,Jung AS,Doi T

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:Second primary malignancies have become the leading cause of death in retinoblastoma survivors. Although osteosarcoma is the most common second malignancy, little is known about its clinical and therapeutic features. METHODS:We retrospectively reviewed a database of patients with retinoblastoma and osteosarc...

journal_title：Japanese journal of clinical oncology

authors： Fujiwara T,Fujiwara M,Numoto K,Ogura K,Yoshida A,Yonemoto T,Suzuki S,Kawai A

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:The CpG island methylator phenotype is strongly associated with poor survival in neuroblastomas. Neuroblastomas with the CpG island methylator phenotype include almost all neuroblastomas with MYCN amplification, and, even among neuroblastomas without MYCN amplification, have worse prognosis. At the same time,...

journal_title：Japanese journal of clinical oncology

authors： Asada K,Watanabe N,Nakamura Y,Ohira M,Westermann F,Schwab M,Nakagawara A,Ushijima T

更新日期：2013-06-01 00:00:00

abstract：BACKGROUNDS:Mutations in the isocitrate dehydrogenase (IDH)1 gene are favourable prognostic factors in newly diagnosed diffuse gliomas, whereas it remains controversial in the recurrent glioblastoma setting. METHODS:A total of 171 patients with newly diagnosed glioblastoma, either 'primary' glioblastoma or 'secondary'...

journal_title：Japanese journal of clinical oncology

authors： Tabei Y,Kobayashi K,Saito K,Shimizu S,Suzuki K,Sasaki N,Shiokawa Y,Nagane M

更新日期：2021-01-01 00:00:00

abstract：:Case 1: A 14-year-old boy with nasopharyngeal cancer (T4N0M0) was treated with stereotactic radiosurgery (SRS) as a boost therapy after conventional radiotherapy. Persistent residual tumor visible with MR remained after conventional radiotherapy comprising 59.6 Gy in total. We therefore performed SRS to add a further ...

journal_title：Japanese journal of clinical oncology

authors： Yokouchi J,Satani K,Kanesaka N,Abe K,Hasegawa T

更新日期：2004-11-01 00:00:00

abstract：:We report the development of a unique enzyme-linked immunosorbent assay (ELISA) which makes possible the detection of leukemia-associated P24 antigen, utilizing its ability to bind the Ricinus communis agglutinin (RCA1) and a monoclonal antibody, SJ-9A4 simultaneously. Using the RCA1/SJ-9A4-ELISA, P24 antigen, as few ...

journal_title：Japanese journal of clinical oncology

authors： Komada Y,Ochiai H,Shimizu K,Azuma E,Kamiya H,Sakurai M

更新日期：1987-12-01 00:00:00

abstract：:A clinical review with analysis of prognostic factors, including the impact of the initial management modality, was conducted on 137 patients with superior vena cava syndrome (SVCS) seen at the Veterans General Hospital-Taipei between 1989 and 1993. Malignant diseases account for most of the SVCS in our Chinese patien...

journal_title：Japanese journal of clinical oncology

authors： Chen YM,Yang S,Perng RP,Tsai CM

更新日期：1995-04-01 00:00:00

abstract：:A case of primary malignant lymphoma of the skull base is reported. A 62-year-old man was admitted with headache and diplopia. Computed tomography and magnetic resonance imaging showed an abnormal mass in the right parasellar region. The final diagnosis after surgery was primary malignant lymphoma of the skull base. P...

journal_title：Japanese journal of clinical oncology

authors： Oyama H,Nagane M,Shibui S,Nomura K,Mukai K

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:To report the results of radiotherapy for patients with failure, adverse reactions or relative contraindications to the use of steroids or immunosuppressants, by using newly developed quantitative indexes. METHODS:Fourteen female and six male patients with Graves' ophthalmopathy were treated with radiothera...

journal_title：Japanese journal of clinical oncology

authors： Sakata K,Hareyama M,Oouchi A,Shidou M,Nagakura H,Morita K,Osanai H,Ohtsuka K,Hinoda Y

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVE:To retrospectively examine the outcomes of hypofractionated stereotactic radiation therapy in three to five fractions for vestibular schwannomas. METHODS:Twenty-five patients with 26 vestibular schwannomas were treated with hypofractionated stereotactic radiation therapy using a CyberKnife. The vestibular sc...

journal_title：Japanese journal of clinical oncology

authors： Morimoto M,Yoshioka Y,Kotsuma T,Adachi K,Shiomi H,Suzuki O,Seo Y,Koizumi M,Kagawa N,Kinoshita M,Hashimoto N,Ogawa K

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:We evaluated the feasibility of combination chemotherapy with paclitaxel, doxorubicin and cisplatin without prophylactic granulocyte colony-stimulating factor injection for intermediate-to-high-risk or recurrent endometrial cancer. METHODS:Women with histologically confirmed FIGO Stages I-II with >1/2 myomet...

journal_title：Japanese journal of clinical oncology

authors： Nagao S,Nishikawa T,Hanaoka T,Kurosaki A,Iwasa N,Hasegawa K,Fujiwara K

更新日期：2014-11-01 00:00:00

abstract：:Bortezomib is a proteasome inhibitor and is active against multiple myeloma. Most toxicities associated with bortezomib are mild to moderate and manageable; however, bortezomib-induced pneumonitis has been reported in some multiple myeloma cases. Bortezomib-induced pneumonitis was reported to occur relatively soon aft...

journal_title：Japanese journal of clinical oncology

authors： Yamaguchi T,Sasaki M,Itoh K

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Tumor marker-producing germ cell tumors of the central nervous system are malignant and require radiation and/or chemotherapy. Although serum beta-human chorionic gonadotropin (hCG) has been used to monitor the course of treatment, the levels of beta-hCG in the cerebrospinal fluid (CSF) have not been measure...

journal_title：Japanese journal of clinical oncology

authors： Fujimaki T,Mishima K,Asai A,Tabuchi K,Kobayashi M,Suzuki I,Kirino T

更新日期：2000-07-01 00:00:00

abstract：:The localization of acidic fibroblast growth factor (aFGF) and basic fibroblast growth factor (bFGF) was investigated immunohistochemically in human benign and malignant thyroid lesions. Immunostaining for aFGF and bFGF displayed diffuse or granular deposits of the reaction products in the cytoplasm of neoplastic cell...

journal_title：Japanese journal of clinical oncology

authors： Kodama M,Daa T,Kashima K,Yokoyama S,Nakayama I,Noguchi S

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:One of the most studied pro-angiogenic factors involved in the development of colorectal cancer is the vascular endothelial growth factor (VEGF). The small molecule tyrosine kinase inhibitor semaxanib (SU5416) is one of the several agents targeting the VEGF signaling pathway, and its development centered mos...

journal_title：Japanese journal of clinical oncology

authors： Hoff PM,Wolff RA,Bogaard K,Waldrum S,Abbruzzese JL

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:To estimate the effect of tumor volume on local-regional control of pharyngolaryngeal cancer by radiotherapy (RT). METHODS:Definitive RT for 48 patients with squamous cell carcinoma of the lateral wall of the oropharynx, pyriform sinus and supraglottic larynx was reviewed. Tumor volume was estimated from co...

journal_title：Japanese journal of clinical oncology

authors： Kawashima M,Ogino T,Fujii H,Ishikura S,Ito Y,Ikeda H

更新日期：1999-10-01 00:00:00

abstract：:One hundred and one cases of lung cancer were immunohistochemically studied for stainability with Leu-7 (anti-myelin fiber associated glycoprotein) and OKT-9 (anti-transferrin receptor) monoclonal antibodies. All small cell carcinomas and carcinoid tumors were positively stained by Leu-7, and 22 of 41 differentiated a...

journal_title：Japanese journal of clinical oncology

authors： Sato Y,Watanabe S,Kodama T,Goto M,Shimosato Y

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to detect the presence of cancer stem-like cells with bronchioalveolar stem cells (BASCs) properties and investigate the clinicopathological role of expression of OCT4 as well as the correlation with clinical outcomes in adenocarcinoma of the lung. METHODS:Specimens of 112 cases...

journal_title：Japanese journal of clinical oncology

authors： Zhang X,Han B,Huang J,Zheng B,Geng Q,Aziz F,Dong Q

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Usually, total and filtered platinum concentrations in plasma are monitored after cisplatin administration. However, these concentrations represent a mixture of unchanged cisplatin and metabolites. In this work, we studied population pharmacokinetic analysis based on these platinum concentrations. METHODS:T...

journal_title：Japanese journal of clinical oncology

authors： Hanada K,Nishijima K,Ogata H,Atagi S,Kawahara M

更新日期：2001-05-01 00:00:00

abstract：:A 56-year-old Japanese man in whom a descending colon carcinoma had been resected underwent a high orchitectomy for metastatic epididymis from the colon. Metastatic carcinoma from the digestive organs to the spermatic cord (SC) and/or the intrascrotal contents (ISC) is rare. Fifty-four Japanese patients with metastasi...

journal_title：Japanese journal of clinical oncology

authors： Kanno K,Ohwada S,Nakamura S,Ohya T,Iino Y,Morishita Y,Hayashi M,Yamanaka H,Fukusato T,Koyama T

更新日期：1994-12-01 00:00:00

abstract：OBJECTIVE:We reviewed the relationship between extent of resection and survival of patients with high-grade gliomas with special consideration of an oligodendroglial component. METHODS:A retrospective review was performed on 160 adult patients with histological diagnosis of high-grade gliomas since 2000. All histologi...

journal_title：Japanese journal of clinical oncology

authors： Yamaguchi S,Kobayashi H,Terasaka S,Ishii N,Ikeda J,Kanno H,Nishihara H,Tanaka S,Houkin K

更新日期：2012-04-01 00:00:00

abstract：Background:The poor clinical prognosis of Stage IIIB colon cancer patients is due in part to the current lack of an effective diagnostic method being available and highlights a need for the identification of novel biomarkers like microRNA (miRNA). Patients and methods:We used microarray analysis to compare the miRNA e...

journal_title：Japanese journal of clinical oncology

authors： Li P,Ou Q,Braciak TA,Chen G,Oduncu FS

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVES:Immune checkpoint inhibitors offer longer survival than chemotherapy in several clinical trials for advanced non-small cell lung cancer. In subset analyses of clinical trials, immune checkpoint inhibitors extended survival in patients aged ≥65 years, but the effects in patients aged ≥75 years are controversi...

journal_title：Japanese journal of clinical oncology

authors： Kubo T,Watanabe H,Ninomiya K,Kudo K,Minami D,Murakami E,Ochi N,Ninomiya T,Harada D,Yasugi M,Ichihara E,Ohashi K,Rai K,Fujiwara K,Hotta K,Tabata M,Maeda Y,Kiura K

更新日期：2020-12-16 00:00:00

abstract：OBJECTIVE:Osteosarcoma is the most common primary malignant bone tumor. The long-term outcome is poor for patients with metastatic disease. METHODS:From June 1989 to January 2008, 202 patients (128 males and 74 females) with high-grade osteosarcoma of the extremities were treated at our institution. Patients were divi...

journal_title：Japanese journal of clinical oncology

authors： Wu PK,Chen WM,Chen CF,Lee OK,Haung CK,Chen TH

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:The value of postmastectomy radiation therapy for breast cancer patients with T1-2 tumor and one to three positive nodes remains controversial. The purpose of this retrospective study was to compare the clinical outcomes of breast cancer patients with T1-2 and one to three positive nodes with and without post...

journal_title：Japanese journal of clinical oncology

authors： Huang CJ,Hou MF,Chuang HY,Lian SL,Huang MY,Chen FM,Fu OY,Lin SF

更新日期：2012-08-01 00:00:00