Primary malignant melanoma of the esophagus: report of four cases.

abstract：OBJECTIVE:Long-term survival and late toxicities of a randomized Phase II study of chemoradiotherapy for esophageal cancer were analyzed. METHODS:Eligible patients were <75 years old and performance status 0-2, and had Stages II-IVA esophageal cancer. For arm A (short-term infusion), cisplatin 70 mg/m(2) Days 1 and 29...

journal_title：Japanese journal of clinical oncology

authors： Nishimura Y,Hiraoka M,Koike R,Nakamatsu K,Itasaka S,Kawamura M,Negoro Y,Araki N,Ishikawa H,Fujii T,Mitsuhashi N

更新日期：2012-09-01 00:00:00

abstract：:The use of lymphokine activated killer (LAK) cells for adoptive transfer therapy has been reported from number of clinical trials. To our knowledge, however, there has been no report concerning the cell cycle progression of LAK cells. Thus, for the present study we have attempted to examine the LAK cell cycle either b...

journal_title：Japanese journal of clinical oncology

authors： Watanabe R,Tanaka N,Naomoto Y,Moreira LF,Orita K

更新日期：1994-04-01 00:00:00

abstract：:Low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT-type lymphoma) is a rare thymic tumor, with only seven previous cases described worldwide to date. We describe the only case to have presented with pulmonary amyloid nodules. A 63-year-old Japanese female was found to have an anterior mediastinal tum...

journal_title：Japanese journal of clinical oncology

authors： Moriyama E,Yokose T,Kodama T,Matsuno Y,Hojo F,Takahashi K,Nagai K,Nishiwaki Y,Ochiai A

更新日期：2000-08-01 00:00:00

abstract：:Cancer originating in the biliary tract can be classified as bile duct cancer (cholangiocarcinoma), gallbladder cancer, or ampullary cancer. Bile duct cancer is further divided to intrahepatic, perihilar and distal bile duct subtypes according to the anatomical location of the tumor. The biological characteristics of ...

journal_title：Japanese journal of clinical oncology

authors： Nara S,Esaki M,Ban D,Takamoto T,Shimada K,Ioka T,Okusaka T,Ishii H,Furuse J

更新日期：2020-12-16 00:00:00

abstract：BACKGROUND:Inconsistency in the prevalence of infection by human papillomavirus (HPV) in lung cancer patients was found between different countries with racial and geographic variations. Our previous reports have indicated that a high-risk HPV 16/18 DNA was frequently detected in Chinese lung cancer patients living in ...

journal_title：Japanese journal of clinical oncology

authors： Fei Y,Yang J,Hsieh WC,Wu JY,Wu TC,Goan YG,Lee H,Cheng YW

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:We evaluated whether color Doppler ultrasound (US) had diagnostic accuracy equal to dynamic computed tomography (CT) and whether performing dynamic CT and Doppler US together would be more informative in preoperative diagnosis of renal solid tumors. METHODS:A total of 110 renal solid tumors smaller than 7 c...

journal_title：Japanese journal of clinical oncology

authors： Kitamura H,Fujimoto H,Tobisu K,Mizuguchi Y,Maeda T,Matsuoka N,Komiyama M,Nakagawa T,Kakizoe T

更新日期：2004-02-01 00:00:00

abstract：:This is a review regarding the current therapeutic strategies in the management of multiple myeloma. Due to the introduction of several new effective therapeutic agents, multiple myeloma is one of the most active and changing fields in clinical oncology. Multiple myeloma is caused by the expansion of monoclonal plasma...

journal_title：Japanese journal of clinical oncology

authors： Suzuki K

更新日期：2013-02-01 00:00:00

abstract：Background:Many patients with colorectal cancer are elderly with competing comorbidities. When constructing nomogram for assessing survival, we should consider the influence of competing risk. A competing-risks nomogram was developed to estimate the probability of death due to colorectal cancer for patients after curat...

journal_title：Japanese journal of clinical oncology

authors： Li J,Li X,Gu J,Ma X,Xue F

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Tumor marker-producing germ cell tumors of the central nervous system are malignant and require radiation and/or chemotherapy. Although serum beta-human chorionic gonadotropin (hCG) has been used to monitor the course of treatment, the levels of beta-hCG in the cerebrospinal fluid (CSF) have not been measure...

journal_title：Japanese journal of clinical oncology

authors： Fujimaki T,Mishima K,Asai A,Tabuchi K,Kobayashi M,Suzuki I,Kirino T

更新日期：2000-07-01 00:00:00

abstract：:Previous studies have demonstrated the monoclonal antibody, TFS-4, to recognize a cell surface antigen, 124,000 Daltons, of molecular weight expressed selectively on small cell lung cancer but not on non-small cell lung cancer, and to cross-react with the human brain, cardiac muscle and some smooth muscle cells. The c...

journal_title：Japanese journal of clinical oncology

authors： Umezawa Y,Kuge S,Kikyo N,Shirai T,Watanabe J,Fugisawa M,Okabe T

更新日期：1991-08-01 00:00:00

abstract：:Human lymphoblastoid interferon-alpha was administered intramuscularly at a dose of 5 x 10(6) units/day to 20 metastatic renal cell carcinoma patients. For potentiating the antitumor effect of interferon, cimetidine was also given to them orally at a dose of 800 mg/day. The combination therapy obtained a complete resp...

journal_title：Japanese journal of clinical oncology

authors： Kotake T,Kinouchi T,Saiki S,Kuroda M,Miki T,Kiyohara H,Usami M

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:We evaluated the efficacy of our quality assurance (QA) program of radiation therapy (RT) in a prospective phase II study. This is the first description of the experience of the Japan Radiation Oncology Group (JAROG) with this program. METHODS:Clinical records, all diagnostic radiological films or color pho...

journal_title：Japanese journal of clinical oncology

authors： Isobe K,Kagami Y,Higuchi K,Kodaira T,Hasegawa M,Shikama N,Nakazawa M,Fukuda I,Nihei K,Ito K,Teshima T,Oguchi M,Japan Radiation Oncology Group (JAROG).

更新日期：2007-02-01 00:00:00

abstract：:Myoepithelioma is a rare neoplasm usually occurring in the salivary glands or the mammary glands but also, more rarely, in the thoracic cavity. The diagnosis of myoepithelioma is based on the presence of histological and immunohistochemical characteristics of myoepithelioma, but in unusual locations, the diagnosis is ...

journal_title：Japanese journal of clinical oncology

authors： Habu T,Soh J,Toji T,Shien K,Niman E,Namba K,Sato H,Yamamoto H,Sugimoto S,Yamane M,Toyooka S

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Second primary head and neck cancers after endoscopic resection of esophageal squamous cell carcinoma adversely affect patients' outcomes and the quality of life; however, an adequate surveillance schedule remains unclear. METHODS:We analyzed 330 patients with early esophageal squamous cell carcinoma who un...

journal_title：Japanese journal of clinical oncology

authors： Shinozaki T,Katada C,Shiga K,Asakage T,Yokoyama T,Yano T,Oda I,Shimizu Y,Takemura K,Ishikawa H,Yokoyama A,Muto M

更新日期：2020-09-28 00:00:00

abstract：Background:Advanced gastric cancer (AGC) and systemic chemotherapy are some of the risk factors for venous thromboembolism (VTE). However, the cumulative incidence, risk factors and prognostic impact of VTE have not been evaluated in Japanese patients with AGC. Methods:This retrospective study included patients who re...

journal_title：Japanese journal of clinical oncology

authors： Arai H,Hironaka S,Minashi K,Denda T,Shimokawa M,Yamaguchi T

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:Since there is now growing interest in the incorporation of patient-reported outcome measures in cancer clinical trials, a patient-based questionnaire, the Patient Neurotoxicity Questionnaire (PNQ) was developed to quantify the symptoms and severity of chemotherapy-induced peripheral neuropathy (CIPN). The ai...

journal_title：Japanese journal of clinical oncology

authors： Kuroi K,Shimozuma K,Ohashi Y,Takeuchi A,Aranishi T,Morita S,Ohsumi S,Watanabe T,Bain S,Hausheer FH

更新日期：2008-11-01 00:00:00

abstract：:Recently, there has been increased interest in the application of preoperative endocrine therapy prior to radical prostatectomy for locally advanced cancer in order to enhance surgical curability and increase survival. Between 1986 and 1993, 40 patients with prostate cancer were given endocrine therapy before radical ...

journal_title：Japanese journal of clinical oncology

authors： Maeda O,Meguro N,Saiki S,Kinouchi T,Kuroda M,Usami M,Kotake T

更新日期：1995-08-01 00:00:00

abstract：:We describe a case of 63-year-old woman with pulmonary artery sarcoma successfully treated with chemotherapy. She developed acute shortness of breath, and left chest and shoulder pain. Although a diagnosis of acute pulmonary embolism was made at a local hospital and she received anticoagulation and thrombolysis therap...

journal_title：Japanese journal of clinical oncology

authors： Uchida A,Tabata M,Kiura K,Tanimoto Y,Kanehiro A,Aoe M,Ohohara N,Ueoka H,Tanimoto M

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:The serum erythropoietin level increases markedly during chemotherapy for leukemia. A number of hypotheses have been built for the mechanism, none of them satisfactory. Difficulty in evaluating bone marrow activity hampers the elucidation. Therefore, we focused on patients who had non-hematological cancer an...

journal_title：Japanese journal of clinical oncology

authors： Sawabe Y,Takiguchi Y,Kikuno K,Iseki T,Ito J,Iida S,Kuriyama T,Yonemitsu H

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to examine the appropriateness of chemotherapy and care in Korean cancer patients near the end-of-life. METHODS:We designed a retrospective cohort composed of patients diagnosed as having metastatic cancer and who received palliative chemotherapy at Seoul National University Hospita...

journal_title：Japanese journal of clinical oncology

authors： Keam B,Oh DY,Lee SH,Kim DW,Kim MR,Im SA,Kim TY,Bang YJ,Heo DS

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVES:Immune checkpoint inhibitors offer longer survival than chemotherapy in several clinical trials for advanced non-small cell lung cancer. In subset analyses of clinical trials, immune checkpoint inhibitors extended survival in patients aged ≥65 years, but the effects in patients aged ≥75 years are controversi...

journal_title：Japanese journal of clinical oncology

authors： Kubo T,Watanabe H,Ninomiya K,Kudo K,Minami D,Murakami E,Ochi N,Ninomiya T,Harada D,Yasugi M,Ichihara E,Ohashi K,Rai K,Fujiwara K,Hotta K,Tabata M,Maeda Y,Kiura K

更新日期：2020-12-16 00:00:00

abstract：:The patient was a 9-year-old premenarcheal pediatric female, whose chief complaint was a well-circumscribed palpable right breast mass without nipple discharge. Although the patient had noticed the lump 2 years prior to hospital admission, its size (1.5 × 1.3 cm) had been stable. There was no family history or previou...

journal_title：Japanese journal of clinical oncology

authors： Yorozuya K,Takahashi E,Kousaka J,Mouri Y,Yoshida M,Fujii K,Akizuki M,Nakano S,Fukutomi T,Umemoto Y,Yokoi T,Imai H

更新日期：2012-03-01 00:00:00

abstract：:A simple and effective method for concentrating sputum in the preparation of smears for cytodiagnosis of lung cancer was developed. The procedure, which utilizes a fixative consisting of 2,3-dihydroxy-1,4-dithiol-butane, 3,5-ditert-butyl-4-hydroxy-toluene, polyoxyethylene-cetyl-ether, polyethylene glycol 1540, and eth...

journal_title：Japanese journal of clinical oncology

authors： Yamagishi K,Koketsu H,Tajima M,Suemasu K

更新日期：1985-06-01 00:00:00

abstract：:In order to determine the significance of androgen receptor (AR) gene mutations for Japanese prostate cancers, we examined the entire coding region, from exon A to H, in 36 primary lesions. Five in stage A, 12 in stage B, six in stage C and 13 in stage D were subjected to PCR-SSCP analysis for genomic DNA and nucleoti...

journal_title：Japanese journal of clinical oncology

authors： Watanabe M,Ushijima T,Shiraishi T,Yatani R,Shimazaki J,Kotake T,Sugimura T,Nagao M

更新日期：1997-12-01 00:00:00

abstract：:Exciting recent advancements in deep-sequencing technology have enabled a rapid and cost-effective molecular characterization of patient-derived tumor samples. Incorporating these innovative diagnostic technologies into early clinical trials could significantly propel implementation of precision medicine by identifyin...

journal_title：Japanese journal of clinical oncology

authors： Bando H,Takebe N

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to specifically investigate the clinicopathological role of expression of vascular endothelial growth factor-C (VEGF-C) as well as the correlation with clinical outcomes in esophageal squamous cell carcinomas (ESCCs). METHODS:Seventy-three patients with ESCC resected in our inst...

journal_title：Japanese journal of clinical oncology

authors： Liu P,Chen W,Zhu H,Liu B,Song S,Shen W,Wang F,Tucker S,Zhong B,Wang D

更新日期：2009-10-01 00:00:00

abstract：:The proband was a 32-year-old man with sparse type of familial adenomatous polyposis with fundic gland and duodenal polyps and congenital hypertrophy of the retinal pigment epithelium without osteoma, dental abnormalities and desmoid tumors. Direct DNA sequencing did not detect germline mutations in any APC exon. Howe...

journal_title：Japanese journal of clinical oncology

authors： Yamaguchi T,Koizumi K,Arai M,Tamura K,Iijima T,Horiguchi S,Miyaki M

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Vascular endothelial growth factor C (VEGF-C) and D (VEGF-D) are considered to be potentially lymphangiogenic and can selectively induce hyperplasia of the lymphatic vasculature. In this study, we aimed to clarify the relation between expression of VEGF-C and -D and lymphatic metastasis in early gastric canc...

journal_title：Japanese journal of clinical oncology

authors： Ishikawa M,Kitayama J,Kazama S,Nagawa H

更新日期：2003-01-01 00:00:00

abstract：:Carcinoid tumors located in the minor duodenal papilla are extremely rare, with only a few cases reported in the literature. Herein, we report the case of a 71-year-old man with a 12-mm carcinoid tumor at the minor duodenal papilla with lymph node metastases. Multidetector-row computed tomography with contrast enhance...

journal_title：Japanese journal of clinical oncology

authors： Fukami Y,Kurumiya Y,Mizuno K,Sekoguchi E,Kobayashi S,Ito A,Tomida A,Onishi S,Shirotsuki R,Okubo K,Narita M

更新日期：2013-01-01 00:00:00

abstract：:During the period 1962-1986, 43 lung cancer patients, 2.3% of the 1,832 patients who underwent pulmonary resections at the National Cancer Center Hospital, Tokyo, had tumors greater than 10 cm in diameter. These 43 cancers were classified postsurgically according to the 1987 guidelines for TNM classification of malign...

journal_title：Japanese journal of clinical oncology

authors： Sano T,Naruke T,Kondo H,Goya T,Tsuchiya R,Suemasu K

更新日期：1990-12-01 00:00:00