Advanced esophageal cancer with esophago-bronchial fistula successfully treated by chemoradiation therapy with additional endoscopic resection: a case report.

abstract：BACKGROUND:Combination of bleomycin, etoposide and cisplatin (BEP) remains the standard chemotherapy for testicular cancer. Since the development of BEP in the 1980s, there has been a considerable advance in supportive therapies, such as granulocyte colony-stimulating-factor and 5-HT3 antagonists. Therefore, we re-eval...

journal_title：Japanese journal of clinical oncology

authors： Kawai K,Ando S,Hinotsu S,Oikawa T,Sekido N,Miyanaga N,Shimazui T,Akaza H

更新日期：2006-07-01 00:00:00

abstract：:This is a review regarding the current therapeutic strategies in the management of multiple myeloma. Due to the introduction of several new effective therapeutic agents, multiple myeloma is one of the most active and changing fields in clinical oncology. Multiple myeloma is caused by the expansion of monoclonal plasma...

journal_title：Japanese journal of clinical oncology

authors： Suzuki K

更新日期：2013-02-01 00:00:00

abstract：:Over the past 10 years, immunotherapy with immune checkpoint inhibitors has revolutionized the management of various cancers. However, immunotherapy in breast cancer has not been successful. Breast cancer has long been recognized as an immunologically 'cold' tumor, although a higher frequency of tumor-infiltrating lym...

journal_title：Japanese journal of clinical oncology

authors： Noguchi E,Shien T,Iwata H

更新日期：2020-12-15 00:00:00

abstract：OBJECTIVE:Osteosarcoma is the most common primary malignant bone tumor. The long-term outcome is poor for patients with metastatic disease. METHODS:From June 1989 to January 2008, 202 patients (128 males and 74 females) with high-grade osteosarcoma of the extremities were treated at our institution. Patients were divi...

journal_title：Japanese journal of clinical oncology

authors： Wu PK,Chen WM,Chen CF,Lee OK,Haung CK,Chen TH

更新日期：2009-08-01 00:00:00

abstract：:Cases of hyperfractionated radiotherapy and adjuvant chemotherapy for nasopharyngeal cancer are reported. Seven patients received hyperfractionated radiotherapy (76.8-81.6 Gy/64-68 fractions to primary tumor) and two cycles of cisplatin (80 mg/m2 i.v. on day 1) plus 5-FU (800 mg/m2 continuous infusion on days 2-6). Mu...

journal_title：Japanese journal of clinical oncology

authors： Toita T,Ogawa K,Kamata M,Kojya S,Itokazu T,Kakinohana Y,Iraha S,Yoshinaga M,Zukeran Y,Sawada S

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVE:To describe changes in Japanese clinical trial regulations after the implementation of the Clinical Trials Act in April 2018. METHODS:First, how to apply multiple regulations after the enforcement of Clinical Trials Act was described. Second, the changes in the number of clinical trials in the National Cance...

journal_title：Japanese journal of clinical oncology

authors： Nakamura K,Shibata T

更新日期：2020-04-07 00:00:00

abstract：Background:Stathmin has been found to be involved in malignant tumors; the aim of this study was to investigate the relationship between serum stathmin and clinico-pathological features of lung cancer. Methods:In three lung cancer cell lines, stathmin expression and its secretion level in the supernatant were examined...

journal_title：Japanese journal of clinical oncology

authors： Biaoxue R,Hua L,Tian F,Wenlong G

更新日期：2017-04-01 00:00:00

abstract：:Immunoperoxidase staining for human keratin proteins was performed cytologically on samples from 90 patients with malignant tumors, and histologically on samples from 164 patients with malignant tumors. At the cytological level, almost all tumor cells not only in squamous cell carcinoma but also in nonsquamous cell ca...

journal_title：Japanese journal of clinical oncology

authors： Yagi Y,Imamura Y,Saku T,Shimotsu T,Hatae M,Yagi S

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVE:Study aims include determination of nationwide structural characteristics of radiation oncology facilities, types of radiation therapy equipment, availability of human resources and trends and comparisons with previous surveys. METHODS:An annual nationwide survey was conducted to collect the statistics of in...

journal_title：Japanese journal of clinical oncology

authors： Ji YH,Jung H,Yang K,Cho CK,Yoo SY,Yoo HJ,Kim KB,Kim MS

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:Oesophageal squamous cell carcinoma is one of the deadliest malignancies worldwide. Contactin-1, a neural adhesion molecule, is implicated in tumour invasion and metastasis. The purpose of this study was to investigate the expression of CNTN-1 in normal and cancerous oesophageal tissue, and the potential rele...

journal_title：Japanese journal of clinical oncology

authors： Liu P,Chen S,Wu W,Liu B,Shen W,Wang F,He X,Zhang S

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:Human papillomavirus vaccines are being introduced worldwide and are expected to reduce the incidence of cervical cancer. Here we report a cross-sectional study using a validated human papillomavirus genotyping method to reveal the human papillomavirus prevalence and genotype distribution in Japanese women wi...

journal_title：Japanese journal of clinical oncology

authors： Azuma Y,Kusumoto-Matsuo R,Takeuchi F,Uenoyama A,Kondo K,Tsunoda H,Nagasaka K,Kawana K,Morisada T,Iwata T,Aoki D,Kukimoto I

更新日期：2014-10-01 00:00:00

abstract：:Exciting recent advancements in deep-sequencing technology have enabled a rapid and cost-effective molecular characterization of patient-derived tumor samples. Incorporating these innovative diagnostic technologies into early clinical trials could significantly propel implementation of precision medicine by identifyin...

journal_title：Japanese journal of clinical oncology

authors： Bando H,Takebe N

更新日期：2015-11-01 00:00:00

abstract：:Human gastrin-releasing peptide (GRP) mRNA was detected in the tumor tissues of medullary thyroid carcinomas and small cell lung carcinomas using synthetic oligodeoxyribonucleotides as hybridization probes. The amount of GRP mRNA was estimated by radiodensitometric hybridization assay. A good correlation was found bet...

journal_title：Japanese journal of clinical oncology

authors： Suzuki M,Yamaguchi K,Abe K,Adachi N,Nagasaki K,Asanuma F,Adachi I,Kimura S,Terada M,Taya Y

更新日期：1987-06-01 00:00:00

abstract：Background:Leiomyosarcoma (LMS) is one of most aggressive mesenchymal malignancies that differentiate towards smooth muscle. The clinical outcome of LMS patients is poor; as such, there is an urgent need for novel therapeutic approaches. Experimental models such as patient-derived cell lines are invaluable tools for pr...

journal_title：Japanese journal of clinical oncology

authors： Sakumoto M,Takahashi M,Oyama R,Takai Y,Kito F,Shiozawa K,Qiao Z,Yoshida A,Endo M,Kawai A,Kondo T

更新日期：2017-10-01 00:00:00

abstract：:A simple and effective method for concentrating sputum in the preparation of smears for cytodiagnosis of lung cancer was developed. The procedure, which utilizes a fixative consisting of 2,3-dihydroxy-1,4-dithiol-butane, 3,5-ditert-butyl-4-hydroxy-toluene, polyoxyethylene-cetyl-ether, polyethylene glycol 1540, and eth...

journal_title：Japanese journal of clinical oncology

authors： Yamagishi K,Koketsu H,Tajima M,Suemasu K

更新日期：1985-06-01 00:00:00

abstract：:We describe a case of 63-year-old woman with pulmonary artery sarcoma successfully treated with chemotherapy. She developed acute shortness of breath, and left chest and shoulder pain. Although a diagnosis of acute pulmonary embolism was made at a local hospital and she received anticoagulation and thrombolysis therap...

journal_title：Japanese journal of clinical oncology

authors： Uchida A,Tabata M,Kiura K,Tanimoto Y,Kanehiro A,Aoe M,Ohohara N,Ueoka H,Tanimoto M

更新日期：2005-07-01 00:00:00

abstract：:Of the patients with colorectal cancer, there are some with hereditary disorders such as familial polyposis coli, Gardner's syndrome, Turcot's syndrome, and cancer family syndrome in which colorectal adenocarcinoma develops at a significantly high frequency, and these hereditary diseases are very important and interes...

journal_title：Japanese journal of clinical oncology

authors： Ushio K

更新日期：1985-04-01 00:00:00

abstract：BACKGROUND:The outcomes of patients with localized or locally advanced prostate cancer treated with external-beam radiotherapy are not well known in Japan. METHODS:Thirty-four institutions combined data on 679 patients with localized or locally advanced prostate cancer treated with a total dose >/=60 Gy between 1995 a...

journal_title：Japanese journal of clinical oncology

authors： Nakamura K,Mizowaki T,Imada H,Karasawa K,Uno T,Onishi H,Nihei K,Sasaki S,Ogura M,Akimoto T

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:The correlations of serum interleukin-6 and soluble interleukin-6 receptor concentrations with clinicopathological features and survival of patients with colorectal cancer were studied. METHODS:We measured the serum levels of interleukin-6 and soluble interleukin-6 receptor in 99 colorectal cancer patients a...

journal_title：Japanese journal of clinical oncology

authors： Yeh KY,Li YY,Hsieh LL,Lu CH,Chou WC,Liaw CC,Tang RP,Liao SK

更新日期：2010-06-01 00:00:00

abstract：:There have been no reports describing acute exacerbations of idiopathic pulmonary fibrosis after particle radiotherapy for non-small cell lung cancer. The present study describes the case of a 76-year-old Japanese man with squamous cell carcinoma of the lung that relapsed in the left upper lobe 1 year after right uppe...

journal_title：Japanese journal of clinical oncology

authors： Nagano T,Kotani Y,Fujii O,Demizu Y,Niwa Y,Ohno Y,Nishio W,Itoh T,Murakami M,Nishimura Y

更新日期：2012-10-01 00:00:00

abstract：:Projecting cancer mortality is fundamental to the process of planning cancer control. Although the prefecture is one of the main units for the implementation and evaluation of cancer control in Japan, a long-term detailed future projection of cancer mortality has not been conducted by prefecture. The main objective of...

journal_title：Japanese journal of clinical oncology

authors： Fukui K,Ito Y,Nakayama T

更新日期：2019-04-01 00:00:00

abstract：:Adult extrarenal nephroblastomas (Wilms' tumor) are extremely rare tumors. They show a higher incidence of non-seminomatous elements and these so-called 'teratoid' Wilms' tumors are suggested to be of germ cell origin. To date, however, the number of reported cases with gonadal teratoma containing nephroblastoma is ve...

journal_title：Japanese journal of clinical oncology

authors： Keskin S,Ekenel M,Başaran M,Aksu C,Kiliçaslan I,Tunç M,Bavbek S

更新日期：2011-08-01 00:00:00

abstract：:A Phase II trial was initiated in Japan to evaluate the efficacy and safety of preoperative chemotherapy with docetaxel, cisplatin and S-1 for gastric cancer with extensive lymph node metastasis. Patients are eligible to participate in the study if they have para-aortic lymph node metastases (stations no. 16a2/16b1) a...

journal_title：Japanese journal of clinical oncology

authors： Katayama H,Ito S,Sano T,Takahari D,Mizusawa J,Boku N,Tsuburaya A,Terashima M,Sasako M,Stomach Cancer Study Group of the Japan Clinical Oncology Group.

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:A combination of cisplatin and vinorelbine chemotherapy is effective in cases of advanced non-small cell lung cancer, but the optimum administration schedule for both drugs has not yet been defined. The aim of this study was to determine the maximum dose of vinorelbine that can be tolerated while receiving a...

journal_title：Japanese journal of clinical oncology

authors： Hotta K,Sekine I,Tamura T,Sawada M,Watanabe H,Kusaba H,Akiyama Y,Inoue A,Shimoyama T,Nokihara H,Ueda Y,Yamamoto N,Kunitoh H,Ohe Y,Kodama T,Saijo N

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:Stage III colorectal cancer is an indication for adjuvant chemotherapy; however, there is no definite view on the selection of regimen. If the recurrence can be predicted, it can serve as the indicator of regimen selection. The present study aimed to predict the recurrence of stage III colorectal cancer by c...

journal_title：Japanese journal of clinical oncology

authors： Ishikawa S,Sawayama H,Matsuo A,Uchino R,Honda S,Hirota M,Baba H

更新日期：2019-03-01 00:00:00

abstract：:We report on an inflammatory pseudotumor of the spleen. A 72-year-old woman visited our hospital complaining of nausea. Physical examination and laboratory investigations were unremarkable. Ultrasonography, computed tomography, magnetic resonance imaging and angiography showed a hypovascular splenic mass measuring abo...

journal_title：Japanese journal of clinical oncology

authors： Noguchi H,Kondo H,Kondo M,Shiraiwa M,Monobe Y

更新日期：2000-04-01 00:00:00

abstract：:A double blind study to compare the efficacy of oral UFT (400 mg Tegafur (FT) plus 896 mg uracil/day) with that of oral FT (800 mg/day) on advanced breast cancer was performed between November, 1986, and November, 1989. Sixty patients were registered for the trial and fifty-six cases were evaluated (28 for UFT and 28 ...

journal_title：Japanese journal of clinical oncology

authors： Tashiro H,Nomura Y,Ohsaki A

更新日期：1994-08-01 00:00:00

abstract：:Head and neck cancer is a major cause of morbidity and mortality in Hong Kong. HNC is well-known for its heterogeneity in epidemiology, clinical behavior, clinic-pathological features and patient characteristics. Treatment strategies for this heterogeneous disease vary greatly in different parts of the world, dependin...

journal_title：Japanese journal of clinical oncology

authors： Ng WT,Wong ECY,Lee VHF,Chan JYW,Lee AWM

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Giant cell tumor (GCT) of bone is a rare and unpredictable lesion. Its standard treatment has ranged from surgical curettage to wide resection and varying oncological and functional results have been reported. METHODS:A retrospective review of 47 patients (17 males and 30 females) with GCT of bone was perfo...

journal_title：Japanese journal of clinical oncology

authors： Oda Y,Miura H,Tsuneyoshi M,Iwamoto Y

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVE:The study objective was to evaluate the efficacy and toxicity of chemoradiotherapy with 5-fluorouracil (5-FU) plus cisplatin in patients with Stage I esophageal squamous cell carcinoma (ESCC). The primary endpoint was proportion of complete response (%CR). METHODS:Patients with Stage I (T1N0M0) ESCC, aged 20...

journal_title：Japanese journal of clinical oncology

authors： Kato H,Sato A,Fukuda H,Kagami Y,Udagawa H,Togo A,Ando N,Tanaka O,Shinoda M,Yamana H,Ishikura S

更新日期：2009-10-01 00:00:00