Detection of gastrin-releasing peptide mRNA in small cell lung carcinomas and medullary thyroid carcinomas using synthetic oligodeoxyribonucleotide probes.

abstract：OBJECTIVE:The purpose of this study is to clarify the efficacy and toxicity of hyperfractionated radiation therapy (RT) for patients with nasopharyngeal cancer (NPC). METHODS:Twenty-two patients with NPC treated at our hospital between April 1994 and December 2002 were the subjects of this study. They received hyperfr...

journal_title：Japanese journal of clinical oncology

authors： Isobe K,Uno T,Kawakami H,Ueno N,Aruga T,Yasuda S,Hanazawa T,Okamoto Y,Ito H,Shigematsu N

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:The study objective was to evaluate the efficacy and toxicity of chemoradiotherapy with 5-fluorouracil (5-FU) plus cisplatin in patients with Stage I esophageal squamous cell carcinoma (ESCC). The primary endpoint was proportion of complete response (%CR). METHODS:Patients with Stage I (T1N0M0) ESCC, aged 20...

journal_title：Japanese journal of clinical oncology

authors： Kato H,Sato A,Fukuda H,Kagami Y,Udagawa H,Togo A,Ando N,Tanaka O,Shinoda M,Yamana H,Ishikura S

更新日期：2009-10-01 00:00:00

abstract：:The risk of a person developing a second primary cancer was evaluated in 1,215 patients with laryngeal cancer at the National Cancer Center Hospital. Overall, 92 (8.2%) of the male patients and 5 (5.7%) of the female patients developed a second cancer, compared with 83.0 and 3.7, respectively, expected on the basis of...

journal_title：Japanese journal of clinical oncology

authors： Kobayashi Y,Arimoto H,Ono I,Watanabe S

更新日期：1990-06-01 00:00:00

abstract：:K-ras mutation is the most common oncogenic alteration in various human cancers including colorectal carcinomas. Point mutations have the potential to activate the K-ras gene if they occur in the critical coding sequences. Almost all of these mutations have been localized in codons 12, 13 and 61. We report a case of c...

journal_title：Japanese journal of clinical oncology

authors： Miyakura Y,Sugano K,Fukayama N,Konishi F,Nagai H

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:The CpG island methylator phenotype is strongly associated with poor survival in neuroblastomas. Neuroblastomas with the CpG island methylator phenotype include almost all neuroblastomas with MYCN amplification, and, even among neuroblastomas without MYCN amplification, have worse prognosis. At the same time,...

journal_title：Japanese journal of clinical oncology

authors： Asada K,Watanabe N,Nakamura Y,Ohira M,Westermann F,Schwab M,Nakagawara A,Ushijima T

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:For several decades, radiotherapy has been widely used to treat metastatic vertebral tumors. This study was designed to assess the feasibility and early clinical outcomes of high-dose radiotherapy to treat such tumors, using helical tomotherapy. METHODS:Between June 2009 and December 2011, 51 sites in 36 pat...

journal_title：Japanese journal of clinical oncology

authors： Lee DS,Kwak YK,Jeong SM,Song JH,Kang YN,Lee SN,Jang HS,Kim YS,Yoon SC,Choi BO

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:Osteosarcoma is the most common primary malignant bone tumor. The long-term outcome is poor for patients with metastatic disease. METHODS:From June 1989 to January 2008, 202 patients (128 males and 74 females) with high-grade osteosarcoma of the extremities were treated at our institution. Patients were divi...

journal_title：Japanese journal of clinical oncology

authors： Wu PK,Chen WM,Chen CF,Lee OK,Haung CK,Chen TH

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:The aims of this randomized, controlled study were to investigate the efficacy and safety of long-term monotherapy with the luteinizing hormone-releasing hormone agonist goserelin acetate compared with both short- and long-term combined androgen blockade. METHODS:Patients with advanced prostate cancer (n = 3...

journal_title：Japanese journal of clinical oncology

authors： Kotake T,Usami M,Akaza H,Koiso K,Homma Y,Kawabe K,Aso Y,Orikasa S,Shimazaki J,Isaka S,Yoshida O,Hirao Y,Okajima E,Naito S,Kumazawa J,Kanetake H,Saito Y,Ohi Y,Ohashi Y

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to re-evaluate post-remission therapy outcomes after first remission according to years of patient enrollment in patients with core binding factor acute myeloid leukaemia. METHODS:We conducted a retrospective study on 138 patients aged less than 60 years diagnosed with core bind...

journal_title：Japanese journal of clinical oncology

authors： Shin HJ,Kim HJ,Sohn SK,Min YH,Won JH,Kim I,Yoon HJ,Lee JH,Jo DY,Joo YD,Jung CW,Lee KH,Korean Society of Hematology, AML\/MDS Working Party.,Chung JS,Ahn JS,Kim SJ,Lee JH,Choi SJ,Lee JH,Bae SH,Hong DS,Zang DY,K

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVES:To evaluate computed tomography findings and assess the clinical course of patients with pulmonary epithelioid hemangioendothelioma. METHODS:Patients diagnosed with pulmonary epithelioid hemangioendothelioma at our institution between 2000 and 2019 were retrospectively analyzed. Patients with pleural involv...

journal_title：Japanese journal of clinical oncology

authors： Onishi Y,Kusumoto M,Goto Y,Kaku S,Motoi N

更新日期：2020-09-28 00:00:00

abstract：OBJECTIVE:Apocrine carcinoma, a subtype of invasive ductal carcinoma of the breast, expresses androgen receptor (AR), but often lacks estrogen receptor (ER) and progesterone receptor (PgR). In the present study, the author immunohistochemically defined apocrine-type carcinoma as ER-/PgR-/AR+ invasive ductal carcinoma a...

journal_title：Japanese journal of clinical oncology

authors： Tsutsumi Y

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Oral carmofur, either as a single or in combination with other chemotherapeutic agents, has been used as adjuvant chemotherapy for curatively resected colon cancer patients. Past trials and meta-analyses indicate that it is somewhat effective in extending survival of patients with this cancer. The objective ...

journal_title：Japanese journal of clinical oncology

authors： Sakamoto J,Hamada C,Rahman M,Kodaira S,Ito K,Nakazato H,Ohashi Y,Yasutomi M

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:We investigated the expression of PyNPase both in cancer cells and in stroma cells to clarify the correlation between PyNPase expression and the prognosis of patients with colorectal cancer. METHODS:Using immunohistochemical staining with an anti-PyNPase antibody, the PyNPase expression in tissues from 114 ...

journal_title：Japanese journal of clinical oncology

authors： Osanai T,Ichikawa W,Takagi Y,Uetake H,Nihei Z,Sugihara K

更新日期：2001-10-01 00:00:00

abstract：:Pelvic lymphadenectomy is generally performed to treat early-stage cervical cancer, and pelvic ± para-aortic lymphadenectomy is performed in patients with endometrial cancer confined to the uterus. However, systematic lymphadenectomy is frequently associated with sequelae including lymphocele, lymphedema and celluliti...

journal_title：Japanese journal of clinical oncology

authors： Niikura H,Tsuji K,Tokunaga H,Shimada M,Ishikawa M,Yaegashi N

更新日期：2019-06-01 00:00:00

abstract：:Acute monocytic leukemia developed in a 77-year-old woman about 18 months after a diagnosis of paroxysmal nocturnal hemoglobinuria (PNH) had been made. The classical features of PNH disappeared with the onset of the leukemia. Chemotherapy with N4-palmitoyl-1-beta-D-arabinosylcytosine and vincristine resulted in the di...

journal_title：Japanese journal of clinical oncology

authors： Kawano F,Chosa M,Matsuoka M,Oyamada N,Takatsuki K

更新日期：1987-06-01 00:00:00

abstract：BACKGROUND:The purpose of the present study is to verify the treatment effects of boron neutron capture therapy (BNCT) in ectopic tumors implanted in the thoracic cavity mimicking malignant pleural mesothelioma (MPM). METHODS:The tumor model was created by implanting murine squamous cell carcinoma cells into the thora...

journal_title：Japanese journal of clinical oncology

authors： Suzuki M,Sakurai Y,Masunaga S,Kinashi Y,Nagata K,Maruhashi A,Ono K

更新日期：2007-04-01 00:00:00

abstract：:The use of lymphokine activated killer (LAK) cells for adoptive transfer therapy has been reported from number of clinical trials. To our knowledge, however, there has been no report concerning the cell cycle progression of LAK cells. Thus, for the present study we have attempted to examine the LAK cell cycle either b...

journal_title：Japanese journal of clinical oncology

authors： Watanabe R,Tanaka N,Naomoto Y,Moreira LF,Orita K

更新日期：1994-04-01 00:00:00

abstract：:Exciting recent advancements in deep-sequencing technology have enabled a rapid and cost-effective molecular characterization of patient-derived tumor samples. Incorporating these innovative diagnostic technologies into early clinical trials could significantly propel implementation of precision medicine by identifyin...

journal_title：Japanese journal of clinical oncology

authors： Bando H,Takebe N

更新日期：2015-11-01 00:00:00

abstract：:The proband was a 32-year-old man with sparse type of familial adenomatous polyposis with fundic gland and duodenal polyps and congenital hypertrophy of the retinal pigment epithelium without osteoma, dental abnormalities and desmoid tumors. Direct DNA sequencing did not detect germline mutations in any APC exon. Howe...

journal_title：Japanese journal of clinical oncology

authors： Yamaguchi T,Koizumi K,Arai M,Tamura K,Iijima T,Horiguchi S,Miyaki M

更新日期：2014-12-01 00:00:00

abstract：:The relations between alcohol consumption and cancers of the breast, corpus uteri and ovary were investigated in a case-control study involving 1,740 cases of breast cancer, 239 cases of cancer of the corpus uteri, 417 cases of ovarian cancer and 8,920 controls with other cancer sites identified from the Aichi Cancer ...

journal_title：Japanese journal of clinical oncology

authors： Kato I,Tominaga S,Terao C

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND:To report the results of radiotherapy for patients with failure, adverse reactions or relative contraindications to the use of steroids or immunosuppressants, by using newly developed quantitative indexes. METHODS:Fourteen female and six male patients with Graves' ophthalmopathy were treated with radiothera...

journal_title：Japanese journal of clinical oncology

authors： Sakata K,Hareyama M,Oouchi A,Shidou M,Nagakura H,Morita K,Osanai H,Ohtsuka K,Hinoda Y

更新日期：1998-06-01 00:00:00

abstract：:Multiple endocrine neoplasia (MEN) 2A is an inherited disease characterized by the development of medullary thyroid carcinoma, pheochromocytoma and hyperparathyroidism. It has recently been shown to be associated with germ-line mutations in the RET proto-oncogene. We describe a 21-year-old man from a MEN 2A family who...

journal_title：Japanese journal of clinical oncology

authors： Yamashita T,Lihara M,Okamoto J,Kanbe M,Ito Y,Kawakami M,Egawa S,Yamaguchi K,Obara T

更新日期：1997-02-01 00:00:00

abstract：OBJECTIVE:We aimed to clarify the suitable surgical management around the paratracheal area of patients who undergo total pharyngolaryngectomy based on the pathological results of hypopharyngeal cancer. METHODS:The study was conducted under a multicenter, retrospective observational design in Japan. We analyzed histop...

journal_title：Japanese journal of clinical oncology

authors： Tomioka T,Beppu T,Fujii T,Ozawa T,Asakage T,Onitsuka T,Fujimoto Y,Matsuura K,Kawabata K,Hayashi R

更新日期：2019-05-01 00:00:00

abstract：:We report a rare case of Bellini duct carcinoma, which is an unusual variant of renal cell carcinoma. The patient, a 56-year-old man, was admitted to our hospital for detailed examination of a renal mass on the left side. He had no clinical symptoms such as gross hematuria or flank pain. Abdominal ultrasonography, com...

journal_title：Japanese journal of clinical oncology

authors： Natsume O,Ozono S,Futami T,Ohta M

更新日期：1997-04-01 00:00:00

abstract：:Nude mice bearing the human oral cavity carcinoma cell line OCC-1, and the lung cancer cell line LC-1, developed a triple paraneoplastic syndrome consisting of hypercalcemia, cachexia and leukocytosis. All of these abnormalities disappeared rapidly after surgical resection of the tumors, suggesting their ectopic humor...

journal_title：Japanese journal of clinical oncology

authors： Tanaka R,Okada M,Kajimura N,Otsubo K,Gyotoku M,Nagasaki K,Ekimoto H,Yamaguchi K

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:No risk factor has been confirmed for para-aortic lymph node (PAN) metastasis from gastric cancer. To identify the risk factors and the most frequent route of metastasis to PAN, we analyzed the prospective data from a phase III trial. METHODS:In JCOG9501 comparing D2 and D2 + PAN dissection, 260 patients wi...

journal_title：Japanese journal of clinical oncology

authors： Nomura E,Sasako M,Yamamoto S,Sano T,Tsujinaka T,Kinoshita T,Furukawa H,Shimizu T,Hiratsuka M,Kobayashi O,Kurokawa Y,Tanigawa N,Gastric Cancer Surgical Study Group of the Japan Clinical Oncology Group.

更新日期：2007-06-01 00:00:00

abstract：:Recently total body irradiation has been used as a method of preparation for the bone marrow transplantation. However, it has become apparent that total body irradiation is one of the causes of interstitial pneumonia. There are several factors in total body irradiation that may induce interstitial pneumonia. 1) Total ...

journal_title：Japanese journal of clinical oncology

authors： Mori T,Ohizumi Y,Maezawa H,Murayama C,Tsuda M,Ando F

更新日期：1984-12-01 00:00:00

abstract：BACKGROUND:Recent studies reported that hospital procedure volume (i.e. volume of patients per hospital receiving a particular treatment)was directly proportional to cancer survival; however the degree of association might be different according to the primary tumor site, extent of disease and year of diagnosis. We per...

journal_title：Japanese journal of clinical oncology

authors： Ioka A,Tsukuma H,Ajiki W,Oshima A

更新日期：2007-07-01 00:00:00

abstract：:Hepatectomy for liver metastasis from the colo-rectum and other organs was performed in 77 cases at the National Cancer Center Hospital. The operative procedures included every variety of hepatectomy from extended resection as trisegmentectomy to small resection as partial resection. The operative mortality rate was 3...

journal_title：Japanese journal of clinical oncology

authors： Yamasaki S,Hasegawa H,Makuuchi M,Koyama Y,Hojo K,Moriya N

更新日期：1985-03-01 00:00:00

abstract：:The incidence of follicular lymphoma in Japan is far lower than that in western countries, and no large-scale clinicopathologic studies on this neoplasm have been conducted in Japan. We reviewed histopathological specimens from 118 of 135 patients who had been diagnosed as having follicular lymphoma between 1968 and 1...

journal_title：Japanese journal of clinical oncology

authors： Katsumata N,Matsuno Y,Nakayama H,Takenaka T,Kobayashi Y,Takeyama K,Narabayashi M,Fukushima T,Yokozawa T,Nakata M,Tajima K,Ikeda H,Tobinai K

更新日期：1996-12-01 00:00:00