Goserelin acetate with or without antiandrogen or estrogen in the treatment of patients with advanced prostate cancer: a multicenter, randomized, controlled trial in Japan. Zoladex Study Group.

abstract：:Interleukin-12 (IL-12), known to be a strong inducer of interferon-gamma (IFN-gamma), plays a vital role in activating the immune surveillance system against intracellular pathogens and malignant tumors. The authors have found that cancer patients showing marked IFN-gamma induction after inoculation with BCG-CWS (the ...

journal_title：Japanese journal of clinical oncology

authors： Hayashi A,Noda A

更新日期：1996-06-01 00:00:00

abstract：:Adult extrarenal nephroblastomas (Wilms' tumor) are extremely rare tumors. They show a higher incidence of non-seminomatous elements and these so-called 'teratoid' Wilms' tumors are suggested to be of germ cell origin. To date, however, the number of reported cases with gonadal teratoma containing nephroblastoma is ve...

journal_title：Japanese journal of clinical oncology

authors： Keskin S,Ekenel M,Başaran M,Aksu C,Kiliçaslan I,Tunç M,Bavbek S

更新日期：2011-08-01 00:00:00

abstract：:The occurrence of multiple primary malignant neoplasms in 9,191 consecutive cases of primary gastrointestinal (GI) tract cancer from 1962 to 1981 at the National Cancer Center was analyzed. The person-years of the cases totaled 28,399.4: 185 second cancers were diagnosed clinically and 85 were first diagnosed at autop...

journal_title：Japanese journal of clinical oncology

authors： Watanabe S,Kodama T,Shimosato Y,Arimoto H,Suemasu K

更新日期：1985-04-01 00:00:00

abstract：:Cancer causes profound suffering for patients, and previous reports have demonstrated that psychological distress, particularly depression, is frequently observed in advanced and/or terminally ill cancer patients. Such depression can lead to serious and far-reaching negative consequences in patients with advanced canc...

journal_title：Japanese journal of clinical oncology

authors： Akechi T

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Recent studies reported that hospital procedure volume (i.e. volume of patients per hospital receiving a particular treatment)was directly proportional to cancer survival; however the degree of association might be different according to the primary tumor site, extent of disease and year of diagnosis. We per...

journal_title：Japanese journal of clinical oncology

authors： Ioka A,Tsukuma H,Ajiki W,Oshima A

更新日期：2007-07-01 00:00:00

abstract：:Technological progress in the field of cancer treatment can be expected to accelerate in the future, giving hope to such patients. At the same time, there is concern that cancer care will become more expensive. It is indispensable to minimize the economic burden of patients to deliver technological advances in treatme...

journal_title：Japanese journal of clinical oncology

authors： Koinuma N

更新日期：2013-04-01 00:00:00

abstract：:Human lymphoblastoid interferon-alpha was administered intramuscularly at a dose of 5 x 10(6) units/day to 20 metastatic renal cell carcinoma patients. For potentiating the antitumor effect of interferon, cimetidine was also given to them orally at a dose of 800 mg/day. The combination therapy obtained a complete resp...

journal_title：Japanese journal of clinical oncology

authors： Kotake T,Kinouchi T,Saiki S,Kuroda M,Miki T,Kiyohara H,Usami M

更新日期：1991-02-01 00:00:00

abstract：:A 50-year-old man underwent a left nephrectomy for renal cell carcinoma of the clear cell type in February, 1978. He was examined using computed tomography in September, 1993, and was found to have a small coin lesion in his right lung. A fine needle aspiration biopsy failed to disclose any tumor cells. He underwent a...

journal_title：Japanese journal of clinical oncology

authors： Yoshida J,Nagai K,Hasebe T,Takahashi K,Nishimura M,Otsuka S,Nishiwaki Y,Kodama T

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:A self-administered quantitative food frequency questionnaire (Qx) was developed for a population-based cohort study on cancer in Takayama, Japan. METHODS:The Qx was tested among 58 male and 59 female volunteers. Average daily nutrient intakes for the previous year calculated from the Qx were compared with ...

journal_title：Japanese journal of clinical oncology

authors： Shimizu H,Ohwaki A,Kurisu Y,Takatsuka N,Ido M,Kawakami N,Nagata C,Inaba S

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:We carried out the present study to investigate the feasibility and effectiveness of concurrent chemoradiotherapy (CT-RT) for postoperative recurrent esophageal cancer, which are, at present, unclear. METHODS:Between 1998 and 2002, 16 patients with postoperative loco-regional recurrence of esophageal cancer...

journal_title：Japanese journal of clinical oncology

authors： Nishimura Y,Koike R,Nakamatsu K,Kanamori S,Suzuki M,Shigeoka H,Shiozaki H

更新日期：2003-07-01 00:00:00

abstract：:Although recent progress in multi-drug chemotherapy has increased the median survival of patients with extensive Small cell lung cancer (SCLC) to 7 months, 2-year survivors are still exceptional. We describe a 40-year-old man with extensive SCLC involving the lungs and systemic nodes who was initially treated with 6 c...

journal_title：Japanese journal of clinical oncology

authors： Shimizu E,Takaue Y,Yamamoto A,Ogura T,Sone S

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Cytokeratins (CKs) 19 and 20 have been used as targets for detecting cancer cells. We attempted to detect circulating cancer cells in patients with gastric cancer using a high-sensitivity reverse transcriptase-polymerase chain reaction (RT-PCR) assay for CK transcripts. METHODS:RT-PCR for CK 19 and CK 20 wa...

journal_title：Japanese journal of clinical oncology

authors： Majima T,Ichikura T,Takayama E,Chochi K,Mochizuki H

更新日期：2000-11-01 00:00:00

abstract：PURPOSE:It is difficult to reproduce a brachytherapy measurement because of changes in the rectal shape during inter-fraction. We constructed a multi-purpose brachytherapy phantom (MPBP) and reproduced the same conditions found in actual therapy. We further attempted to apply the measured optimal dose to reduce rectal ...

journal_title：Japanese journal of clinical oncology

authors： Huh H,Kim W,Loh JJ,Lee S,Kim CY,Lee S,Shin D,Shin D,Cho S,Jang J,Lim S,Cho KH,Kwon S,Kim S

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:To confirm the safety and efficacy of everolimus in patients with unresectable or metastatic RCC. METHODS:Patients with unresectable or metastatic RCC were included and were followed for up to 1 year from the start of everolimus. The study was conducted at 618 investigational sites in Japan from March 2010 t...

journal_title：Japanese journal of clinical oncology

authors： Akaza H,Kurihara R,Katsura A,Harumiya M,Ushida N

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Uracil-tegafur (UFT) has been reported to have broad antitumor activity in a variety of malignancies. However, its activity in biliary tract carcinoma has not been fully evaluated. The aim of this study was to evaluate the antitumor activity and toxicity of UFT in chemotherapy-naive patients with advanced bi...

journal_title：Japanese journal of clinical oncology

authors： Ikeda M,Okusaka T,Ueno H,Morizane C,Furuse J,Ishii H

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Stage III colorectal cancer is an indication for adjuvant chemotherapy; however, there is no definite view on the selection of regimen. If the recurrence can be predicted, it can serve as the indicator of regimen selection. The present study aimed to predict the recurrence of stage III colorectal cancer by c...

journal_title：Japanese journal of clinical oncology

authors： Ishikawa S,Sawayama H,Matsuo A,Uchino R,Honda S,Hirota M,Baba H

更新日期：2019-03-01 00:00:00

abstract：Background:Malignant pleural effusion is a commonly seen complication of malignancies such as lung and breast cancers. In Western countries, talc is frequently used as a standard therapeutic agent (pleurodesis agent) with the aim of alleviating symptoms including dyspnea and chest pain. Talc is not recognized as a pleu...

journal_title：Japanese journal of clinical oncology

authors： Saka H,Oki M,Kitagawa C,Kogure Y,Kojima Y,Saito AM,Ishida A,Miyazawa T,Takeda K,Nakagawa K,Sasada S,Negoro S

更新日期：2018-04-01 00:00:00

abstract：BACKGROUNDS:Mutations in the isocitrate dehydrogenase (IDH)1 gene are favourable prognostic factors in newly diagnosed diffuse gliomas, whereas it remains controversial in the recurrent glioblastoma setting. METHODS:A total of 171 patients with newly diagnosed glioblastoma, either 'primary' glioblastoma or 'secondary'...

journal_title：Japanese journal of clinical oncology

authors： Tabei Y,Kobayashi K,Saito K,Shimizu S,Suzuki K,Sasaki N,Shiokawa Y,Nagane M

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:Osteosarcoma is the most common primary malignant bone tumor. The long-term outcome is poor for patients with metastatic disease. METHODS:From June 1989 to January 2008, 202 patients (128 males and 74 females) with high-grade osteosarcoma of the extremities were treated at our institution. Patients were divi...

journal_title：Japanese journal of clinical oncology

authors： Wu PK,Chen WM,Chen CF,Lee OK,Haung CK,Chen TH

更新日期：2009-08-01 00:00:00

abstract：:There has been no previous report of oxaliplatin administration in patients undergoing hemodialysis. A 65-year-old female with end-stage renal disease who was undergoing hemodialysis presented with anemia in August 2005. She was diagnosed with colon cancer with multiple liver metastases. After colectomy, hepatic arter...

journal_title：Japanese journal of clinical oncology

authors： Shitara K,Munakata M,Muto O,Okada R,Mitobe S,Mino M,Ikami I,Sakata Y

更新日期：2007-07-01 00:00:00

abstract：:Previous studies have demonstrated the monoclonal antibody, TFS-4, to recognize a cell surface antigen, 124,000 Daltons, of molecular weight expressed selectively on small cell lung cancer but not on non-small cell lung cancer, and to cross-react with the human brain, cardiac muscle and some smooth muscle cells. The c...

journal_title：Japanese journal of clinical oncology

authors： Umezawa Y,Kuge S,Kikyo N,Shirai T,Watanabe J,Fugisawa M,Okabe T

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:The Patterns of Care Study (USPCS) by the American College of Radiology (ACR) has made significant contributions to improvements in the procedures of care for patients with breast cancer in the USA. The purpose of this study was to identify problems associated with the process of care for patients undergoing...

journal_title：Japanese journal of clinical oncology

authors： Shikama N,Nishikawa A,Mitsumori M,Hiraoka M,Yamamoto T,Teshima T,Inoue T,Wilson F,Owen J

更新日期：2003-10-01 00:00:00

abstract：:Although malignant lymphoma of the breast is a rare disease, we recently experienced a high incidence of central nervous system (CNS) involvement. Thus, we retrospectively reviewed clinical records of 921 patients with breast tumors, treated from 1990 to 2002, to examine CNS involvement. Eight patients were found to h...

journal_title：Japanese journal of clinical oncology

authors： Yamazaki H,Hanada M,Kitada M,Kuyama J,Sato T,Nishikubo M,Ishida T,Inoue T,Inoue T

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVES:ATPase family AAA domain-containing 2 plays an important role in tumor progression including cell cycle, proliferation, apoptosis and chemoresistance. However, the expression of ATPase family AAA domain-containing 2 in colorectal cancer and its significance are still unclear. The aim of this study was to exa...

journal_title：Japanese journal of clinical oncology

authors： Hou M,Huang R,Song Y,Feng D,Jiang Y,Liu M

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:In Japan, there had been no prospective clinical studies conducted in terms of modified FOLFOX6 + bevacizumab therapy. We performed a post-marketing Phase II multicenter clinical study to examine the efficacy and safety of this regimen as first-line therapy for Japanese patients with advanced/recurrent colore...

journal_title：Japanese journal of clinical oncology

authors： Nishina T,Takano Y,Denda T,Yasui H,Takeda K,Ura T,Esaki T,Okuyama Y,Kondo K,Takahashi Y,Sugiyama Y,Muro K

更新日期：2013-11-01 00:00:00

abstract：:Cases of hyperfractionated radiotherapy and adjuvant chemotherapy for nasopharyngeal cancer are reported. Seven patients received hyperfractionated radiotherapy (76.8-81.6 Gy/64-68 fractions to primary tumor) and two cycles of cisplatin (80 mg/m2 i.v. on day 1) plus 5-FU (800 mg/m2 continuous infusion on days 2-6). Mu...

journal_title：Japanese journal of clinical oncology

authors： Toita T,Ogawa K,Kamata M,Kojya S,Itokazu T,Kakinohana Y,Iraha S,Yoshinaga M,Zukeran Y,Sawada S

更新日期：1999-03-01 00:00:00

abstract：:Comprehensive genomic profiling using next-generation sequencing technologies provides insights into understanding the genomic architecture of human cancer. This new understanding of the cancer genome allows us to identify many more genomic alterations occurring within tumors than before, some of which could be potent...

journal_title：Japanese journal of clinical oncology

authors： Kou T,Kanai M,Matsumoto S,Okuno Y,Muto M

更新日期：2016-05-01 00:00:00

abstract：:A clinical review with analysis of prognostic factors, including the impact of the initial management modality, was conducted on 137 patients with superior vena cava syndrome (SVCS) seen at the Veterans General Hospital-Taipei between 1989 and 1993. Malignant diseases account for most of the SVCS in our Chinese patien...

journal_title：Japanese journal of clinical oncology

authors： Chen YM,Yang S,Perng RP,Tsai CM

更新日期：1995-04-01 00:00:00

abstract：INTRODUCTION:Thymic epithelial tumors are a rare type of neoplasm. Accordingly, it is difficult to perform phase III trials in patients with thymic epithelial tumors, and thus, no standard treatment has been established for these tumors. In this study, we aimed to investigate the current status of thymic epithelial tum...

journal_title：Japanese journal of clinical oncology

authors： Kanemura H,Tamura T,Nishimura N,Kobayashi D,Higashi T

更新日期：2020-03-09 00:00:00

abstract：OBJECTIVE:Breast cancer is a heterogeneous disease. The aim of this prospective study, in which fluorescence in situ hybridization was used to determine human epidermal growth factor receptor 2 status in primary breast cancers and in the lymph node metastases, was to verify the stability of human epidermal growth facto...

journal_title：Japanese journal of clinical oncology

authors： Aoyama K,Kamio T,Nishikawa T,Kameoka S

更新日期：2010-07-01 00:00:00