The diagnostic value of histology and cytology samples during endobronchial ultrasound with a guide sheath.

abstract：OBJECTIVE:This phase I/II study determined the recommended dose of FOLFIRI (irinotecan, infusional 5-fluorouracil and leucovorin) for Japanese patients with advanced colorectal cancer, and evaluated safety at the recommended dose in patients without the UDP-glucuronosyltransferase 1A1*28 allele which caused reduced enz...

journal_title：Japanese journal of clinical oncology

authors： Yamashita K,Nagashima F,Fujita K,Yamamoto W,Endo H,Miya T,Narabayashi M,Kawara K,Akiyama Y,Ando Y,Ando M,Sasaki Y

更新日期：2011-02-01 00:00:00

abstract：:A case of ovarian cystadenocarcinoma associated with pregnancy is reported. The semicystic left ovarian tumor was found in a 28-year-old woman, gravida 2, para 1 at 33 weeks' gestation. A primary Cesarean section, total abdominal hysterectomy and bilateral salpingo-oophorectomy followed by chemotherapy were performed....

journal_title：Japanese journal of clinical oncology

authors： Sawada M,Yamasaki M,Urabe T,Katayama S,Yamane T

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:The purpose of the present study is to verify the treatment effects of boron neutron capture therapy (BNCT) in ectopic tumors implanted in the thoracic cavity mimicking malignant pleural mesothelioma (MPM). METHODS:The tumor model was created by implanting murine squamous cell carcinoma cells into the thora...

journal_title：Japanese journal of clinical oncology

authors： Suzuki M,Sakurai Y,Masunaga S,Kinashi Y,Nagata K,Maruhashi A,Ono K

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Vital dye-guided sentinel node biopsy is affordable in most hospitals, but may be of limited accuracy in identifying all sentinel nodes. Leaving sentinel nodes in the axilla may result in a false nodal staging of breast carcinomas. METHODS:From a series of 112 successful sentinel lymph node biopsies with Pa...

journal_title：Japanese journal of clinical oncology

authors： Cserni G,Rajtár M,Boross G

更新日期：2000-06-01 00:00:00

abstract：:Human gastrin-releasing peptide (GRP) mRNA was detected in the tumor tissues of medullary thyroid carcinomas and small cell lung carcinomas using synthetic oligodeoxyribonucleotides as hybridization probes. The amount of GRP mRNA was estimated by radiodensitometric hybridization assay. A good correlation was found bet...

journal_title：Japanese journal of clinical oncology

authors： Suzuki M,Yamaguchi K,Abe K,Adachi N,Nagasaki K,Asanuma F,Adachi I,Kimura S,Terada M,Taya Y

更新日期：1987-06-01 00:00:00

abstract：:Peripheral plasma prostaglandins (PGs) were assayed in 10 cases of gynecologic malignancies. In addition, fluctuations of PG levels during chemotherapeutically-induced gastrointestinal toxicity as well as those caused by a bolus infusion of steroid hormone were investigated. As a result, the level of PGE2 in most case...

journal_title：Japanese journal of clinical oncology

authors： Suzuki M,Ohwada M,Tamada T

更新日期：1987-09-01 00:00:00

abstract：Background:Stathmin has been found to be involved in malignant tumors; the aim of this study was to investigate the relationship between serum stathmin and clinico-pathological features of lung cancer. Methods:In three lung cancer cell lines, stathmin expression and its secretion level in the supernatant were examined...

journal_title：Japanese journal of clinical oncology

authors： Biaoxue R,Hua L,Tian F,Wenlong G

更新日期：2017-04-01 00:00:00

abstract：:Comprehensive genomic profiling using next-generation sequencing technologies provides insights into understanding the genomic architecture of human cancer. This new understanding of the cancer genome allows us to identify many more genomic alterations occurring within tumors than before, some of which could be potent...

journal_title：Japanese journal of clinical oncology

authors： Kou T,Kanai M,Matsumoto S,Okuno Y,Muto M

更新日期：2016-05-01 00:00:00

abstract：:Primary mesenteric liposarcoma is a rare entity that has been reported only 14 times in English literature. The treatment strategy for mesenteric liposarcoma is, if no distant metastases are detected, surgical resection with a wide surgical margin, often followed by radiation and/or adjuvant chemotherapy for high-risk...

journal_title：Japanese journal of clinical oncology

authors： Ishiguro S,Yamamoto S,Chuman H,Moriya Y

更新日期：2006-11-01 00:00:00

abstract：:A case of primary malignant lymphoma of the skull base is reported. A 62-year-old man was admitted with headache and diplopia. Computed tomography and magnetic resonance imaging showed an abnormal mass in the right parasellar region. The final diagnosis after surgery was primary malignant lymphoma of the skull base. P...

journal_title：Japanese journal of clinical oncology

authors： Oyama H,Nagane M,Shibui S,Nomura K,Mukai K

更新日期：1992-04-01 00:00:00

abstract：:A prospective multicenter trial has been started in Korea to investigate the treatment efficacy of a levonorgestrel-releasing intrauterine system plus medroxyprogesterone acetate in young women with early-stage endometrial cancer. A number of studies have reported the effectiveness of hormonal therapy using systemic p...

journal_title：Japanese journal of clinical oncology

authors： Kim MK,Seong SJ,Lee TS,Kim JW,Nam BH,Hong SR,Suh KS

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:To investigate practical patterns for stereotactic body radiotherapy to hepatocellular carcinoma in Korea. METHODS:In June 2013, the Korean Stereotactic Radiosurgery Group of the Korean Society for Radiation Oncology conducted a national patterns-of-care survey about stereotactic body radiotherapy to the liv...

journal_title：Japanese journal of clinical oncology

authors： Bae SH,Kim MS,Jang WI,Kay CS,Kim W,Kim ES,Kim JH,Kim JH,Yang KM,Lee KC,Chang AR,Jo S

更新日期：2016-04-01 00:00:00

abstract：:Adjuvant chemotherapy with S-1 is a standard treatment for patients with stage II/III gastric cancer after D2 gastrectomy; however, this is not uniformly applicable in older patients. The Stomach Cancer Study Group of the Japan Clinical Oncology Group conducted a questionnaire survey on older patients aged ≥80 years a...

journal_title：Japanese journal of clinical oncology

authors： Mizutani T,Yamaguchi K,Mizusawa J,Ito S,Nishida Y,Yabusaki H,Boku N,Sano T,Yoshida K,Sasako M,Yoshikawa T,Terashima M,Stomach Cancer Study Group\/Japan Clinical Oncology Group.

更新日期：2018-12-01 00:00:00

abstract：:The Lugano classification was published in 2014 to form the basis for revising the recommendations regarding anatomic staging and evaluation of disease before and after therapy. This staging system was adopted by the eighth edition of the Cancer Staging Manual of the American Joint Committee on Cancer. In this review,...

journal_title：Japanese journal of clinical oncology

authors： Munakata W,Terauchi T,Maruyama D,Nagai H

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:Long-term survival and late toxicities of a randomized Phase II study of chemoradiotherapy for esophageal cancer were analyzed. METHODS:Eligible patients were <75 years old and performance status 0-2, and had Stages II-IVA esophageal cancer. For arm A (short-term infusion), cisplatin 70 mg/m(2) Days 1 and 29...

journal_title：Japanese journal of clinical oncology

authors： Nishimura Y,Hiraoka M,Koike R,Nakamatsu K,Itasaka S,Kawamura M,Negoro Y,Araki N,Ishikawa H,Fujii T,Mitsuhashi N

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:The serum erythropoietin level increases markedly during chemotherapy for leukemia. A number of hypotheses have been built for the mechanism, none of them satisfactory. Difficulty in evaluating bone marrow activity hampers the elucidation. Therefore, we focused on patients who had non-hematological cancer an...

journal_title：Japanese journal of clinical oncology

authors： Sawabe Y,Takiguchi Y,Kikuno K,Iseki T,Ito J,Iida S,Kuriyama T,Yonemitsu H

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE:We performed a retrospective review of clinical T1a renal cell carcinoma patients treated in our institution. The clinicopathological findings and patients' prognoses were analyzed according to tumor size, and risk factors for tumor recurrence were elucidated. METHODS:A total of 140 cases of sporadic renal c...

journal_title：Japanese journal of clinical oncology

authors： Kitagawa Y,Nakashima K,Shima T,Izumi K,Narimoto K,Miwa S,Miyagi T,Maeda Y,Kadono Y,Konaka H,Mizokami A,Namiki M

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:There have been few reports of sarcoid reaction in the regional lymph nodes associated with lung cancer. The purpose of this study was to analyze the surgical results of lung cancer with sarcoid reaction. METHODS:Of 1733 lung cancer patients undergoing surgical treatment in our institute from 1990 to 2004, ...

journal_title：Japanese journal of clinical oncology

authors： Tomimaru Y,Higashiyama M,Okami J,Oda K,Takami K,Kodama K,Tsukamoto Y

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVE:Cholangiocarcinoma (CCA) is a primary malignancy, which is often diagnosed as advanced and inoperable due to the lack of effective biomarkers and poor sensitivity of clinical diagnosis. Here, we aimed to identify the genomic profile of CCA and provided molecular evidence for further biomarker development. ME...

journal_title：Japanese journal of clinical oncology

authors： Jiang G,Zhang W,Wang T,Ding S,Shi X,Zhang S,Shi W,Liu A,Zheng S

更新日期：2020-09-28 00:00:00

abstract：:Sarcoma of the hypopharynx has been reported very rarely in the literature, only six cases having been found among all head and neck malignancies reported to SEER (Surveillance, Epidemiology, and End Results) during 1973-1987. We report a 14-year-old boy with a huge malignant soft tissue sarcoma arising from the hypop...

journal_title：Japanese journal of clinical oncology

authors： Lin JC,Hsu CY,Kwan PC,Shen WC,Jan JS,Ho WL

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:CD10 is a cell surface metalloproteinase expressed by a variety of normal cell types, including lymphoid precursor cells, germinal center B lymphocytes and some epithelial cells. Although accumulating data indicate that CD10 expression by stromal cells is involved in colorectal carcinogenesis and it is a nov...

journal_title：Japanese journal of clinical oncology

authors： Huang WB,Zhou XJ,Chen JY,Zhang LH,Meng K,Ma HH,Lu ZF

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to assess clinically the adequacy of vessel-contouring-based pelvic radiotherapy with regard to nodal coverage for uterine cervical cancer. METHODS:Fifty patients with Stages I-III cervical cancer, treated with vessel-contouring-based three-dimensional radiotherapy since August 2002...

journal_title：Japanese journal of clinical oncology

authors： Uno T,Isobe K,Ueno N,Kobayashi H,Sanayama Y,Mitsuhashi A,Shozu M,Ito H

更新日期：2009-06-01 00:00:00

abstract：:A 72-year-old man was found to have a 12 mm solid lesion in the pancreatic tail and an 8 mm cystic lesion in the body of the pancreas by computed tomography carried out during a routine follow-up study of his adult-onset diabetes mellitus. A distal pancreatectomy was performed revealing the pancreas to have an adenoca...

journal_title：Japanese journal of clinical oncology

authors： Yoshida J,Ozaki H,Yamamoto J,Kosuge T,Takayasu K,Muramatsu Y,Mukai K

更新日期：1991-12-01 00:00:00

abstract：OBJECTIVE:To assess the resectability rate of patients with initially unresectable liver-only metastases from colorectal cancer (CRC) after treatment with irinotecan/capecitabine. METHODS:Patients received irinotecan (240 mg/m(2)) as a 30 min intravenous infusion on day 1 and capecitabine (1000 mg/m(2)) orally bid for...

journal_title：Japanese journal of clinical oncology

authors： Zhao R,Zhu J,Ji X,Cai J,Wan F,Li Q,Zhong B,Tucker S,Wang D

更新日期：2010-01-01 00:00:00

abstract：:The occurrence of multiple primary cancers in the aerodigestive tract is a well known phenomenon that has been explained by the concept of 'field carcinogenesis'. Metachronous or synchronous esophageal cancer has usually been identified in patients with head and neck cancer, gastric cancer or colon cancer. The inciden...

journal_title：Japanese journal of clinical oncology

authors： Naomoto Y,Haisa M,Yamatsuji T,Shirakawa Y,Muramatsu T,Isozaki H,Kamikawa Y,Tanaka N

更新日期：1999-07-01 00:00:00

abstract：OBJECTIVE:To describe changes in Japanese clinical trial regulations after the implementation of the Clinical Trials Act in April 2018. METHODS:First, how to apply multiple regulations after the enforcement of Clinical Trials Act was described. Second, the changes in the number of clinical trials in the National Cance...

journal_title：Japanese journal of clinical oncology

authors： Nakamura K,Shibata T

更新日期：2020-04-07 00:00:00

abstract：:Due to the rapid aging of Japan's population, clinical research focusing on older patients with cancer is urgently needed. The Japan Clinical Oncology Group (JCOG) has conducted several such clinical trials, but there has been no formal policy for geriatric research. We have therefore established a JCOG policy for ger...

journal_title：Japanese journal of clinical oncology

authors： Mizutani T,Nakamura K,Fukuda H,Ogawa A,Hamaguchi T,Nagashima F,Geriatric Study Committee\/Japan Clinical Oncology Group.

更新日期：2019-10-01 00:00:00

abstract：:Endometrial stromal sarcoma is known to be a hormone-dependent tumor. Efficacy of hormonal therapy including high-dose progestins, aromatase inhibitors or gonadotropin-releasing hormone analogs has been reported. We report a case of recurrent endometrial stromal sarcoma, the tumor cells of which were strongly positive...

journal_title：Japanese journal of clinical oncology

authors： Akashi D,Todo Y,Shimada C,Okamoto K,Minobe S,Kato H

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Although there have been extensive studies to determine risk factors affecting survival after resection for hepatocellular carcinoma (HCC), we still do not know which patients can survive disease free after curative resection. This study was undertaken to determine independent risk factors affecting the leng...

journal_title：Japanese journal of clinical oncology

authors： Takata M,Yamanaka N,Tanaka T,Yamanaka J,Maeda S,Okamoto E,Yasojima H,Uematsu K,Watanabe H,Uragari Y

更新日期：2000-02-01 00:00:00

abstract：OBJECTIVE:This multicenter, open-label, single-arm, Phase II study assessed the efficacy of a neoadjuvant chemotherapy with docetaxel (75 mg/m(2) q3w) followed by 5-fluorouracil 500 mg/m(2), epirubicin 100 mg/m(2) and cyclophosphamide 500 mg/m(2) q3w in patients with early-stage breast cancer. METHODS:Women with resec...

journal_title：Japanese journal of clinical oncology

authors： Iwata H,Sato N,Masuda N,Nakamura S,Yamamoto N,Kuroi K,Kurosumi M,Tsuda H,Akiyama F,Ohashi Y,Toi M

更新日期：2011-07-01 00:00:00