Immunomodulatory drugs in the treatment of multiple myeloma.

abstract：BACKGROUND:Second primary head and neck cancers after endoscopic resection of esophageal squamous cell carcinoma adversely affect patients' outcomes and the quality of life; however, an adequate surveillance schedule remains unclear. METHODS:We analyzed 330 patients with early esophageal squamous cell carcinoma who un...

journal_title：Japanese journal of clinical oncology

authors： Shinozaki T,Katada C,Shiga K,Asakage T,Yokoyama T,Yano T,Oda I,Shimizu Y,Takemura K,Ishikawa H,Yokoyama A,Muto M

更新日期：2020-09-28 00:00:00

abstract：OBJECTIVE:Despite the clinical similarities triple-negative and basal-like breast cancer are not synonymous. Indeed, not all basal-like cancers are negative for estrogen receptor, progesterone receptor and HER2 expression while triple-negative also encompasses other cancer types. P53 protein appears heterogeneously exp...

journal_title：Japanese journal of clinical oncology

authors： Biganzoli E,Coradini D,Ambrogi F,Garibaldi JM,Lisboa P,Soria D,Green AR,Pedriali M,Piantelli M,Querzoli P,Demicheli R,Boracchi P,Nenci I,Ellis IO,Alberti S

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:This multicenter, open-label, single-arm, Phase II study assessed the efficacy of a neoadjuvant chemotherapy with docetaxel (75 mg/m(2) q3w) followed by 5-fluorouracil 500 mg/m(2), epirubicin 100 mg/m(2) and cyclophosphamide 500 mg/m(2) q3w in patients with early-stage breast cancer. METHODS:Women with resec...

journal_title：Japanese journal of clinical oncology

authors： Iwata H,Sato N,Masuda N,Nakamura S,Yamamoto N,Kuroi K,Kurosumi M,Tsuda H,Akiyama F,Ohashi Y,Toi M

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Benefits of chemotherapy have generally been modest in gastric cancer, although those regimens developed more recently have produced higher response rates. Paclitaxel plus cisplatin is one such regimen and divided administration of paclitaxel has been suggested to be associated with lower neurological and he...

journal_title：Japanese journal of clinical oncology

authors： Kim YH,Yamaguchi K,Bang YJ,Takiuchi H,Kang WK,Sato A,Kang YK,Sakamoto J,Abe C,Sakata Y

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:Emotional distress is considered to be higher in patients with head and neck cancer than other types of cancer. The present study aimed to identify predictors of the postoperative levels of depression in patients with head and neck cancer who have undergone surgery. METHODS:Postoperative levels of depression...

journal_title：Japanese journal of clinical oncology

authors： Adachi Y,Kimura H,Sato N,Nagashima W,Nakamura K,Aleksic B,Yoshida K,Fujimoto Y,Nakashima T,Ozaki N

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:To assess the feasibility and outcome of concurrent chemoradiotherapy (CT-RT) with large regional field and high-dose external beam boost irradiation in thoracic esophageal cancer. METHODS:Patients with clinical stage T1 (submucosal)-4N0-1M0 (UICC 1997) squamous cell carcinoma of the thoracic esophagus were ...

journal_title：Japanese journal of clinical oncology

authors： Toita T,Ogawa K,Adachi G,Kakinohana Y,Nishikuramori Y,Iraha S,Utsunomiya T,Murayama S

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVE:We evaluated the results of imatinib dose escalation in patients with advanced gastrointestinal stromal tumors (GISTs) after disease progression on standard-dose imatinib. METHODS:Clinical data from patients with metastatic or unresectable GISTs whose dose of imatinib was increased after disease progression ...

journal_title：Japanese journal of clinical oncology

authors： Park I,Ryu MH,Sym SJ,Lee SS,Jang G,Kim TW,Chang HM,Lee JL,Lee H,Kang YK

更新日期：2009-02-01 00:00:00

abstract：:A phase II study of chemoradiotherapy for advanced squamous cell carcinoma of the thoracic esophagus was carried out cooperatively by nine Japanese institutions. Forty-five patients with thoracic advanced squamous cell carcinoma, who had T4 tumor or distant lymph node metastasis (M1(LYM)), were enrolled in the study f...

journal_title：Japanese journal of clinical oncology

authors： Ishida K,Iizuka T,Ando N,Ide H

更新日期：1996-10-01 00:00:00

abstract：:A prospective multicenter trial has been started in Korea to investigate the treatment efficacy of a levonorgestrel-releasing intrauterine system plus medroxyprogesterone acetate in young women with early-stage endometrial cancer. A number of studies have reported the effectiveness of hormonal therapy using systemic p...

journal_title：Japanese journal of clinical oncology

authors： Kim MK,Seong SJ,Lee TS,Kim JW,Nam BH,Hong SR,Suh KS

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Although there have been extensive studies to determine risk factors affecting survival after resection for hepatocellular carcinoma (HCC), we still do not know which patients can survive disease free after curative resection. This study was undertaken to determine independent risk factors affecting the leng...

journal_title：Japanese journal of clinical oncology

authors： Takata M,Yamanaka N,Tanaka T,Yamanaka J,Maeda S,Okamoto E,Yasojima H,Uematsu K,Watanabe H,Uragari Y

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Although a series of histopathological criteria have been suggested, the prediction of the malignant potential of gastrointestinal stromal tumors (GIST) is still difficult. The older literature called all gastrointestinal stromal tumors smooth muscle tumors or mixed GIST with true smooth muscle tumors. Repor...

journal_title：Japanese journal of clinical oncology

authors： Wang X,Mori I,Tang W,Utsunomiya H,Nakamura M,Nakamura Y,Zhou G,Kennichi K

更新日期：2002-09-01 00:00:00

abstract：:An immunohistochemical study of a rare initial manifestation of non-Hodgkin's lymphoma (NHL) in the ovaries is presented. There have been very few reports to date on immunohistochemical studies of lymphoma involving the ovaries. A 53-year-old woman suffering from lower abdominal pain and abnormal genital bleeding was ...

journal_title：Japanese journal of clinical oncology

authors： Yamane T,Kirimoto K,Fujita M,Naka T,Tsubakio T,Ishikawa K,Nobunaga T,Tanaka F,Yamasaki M

更新日期：1989-06-01 00:00:00

abstract：OBJECTIVE:Anatomical segmentectomy has the potential to replace lobectomy as the standard procedure for early stage non-small cell lung cancer. We investigated the safety and feasibility of robotic anatomical segmentectomy for non-small cell lung cancer. METHODS:Overall 20 patients underwent robotic anatomical segment...

journal_title：Japanese journal of clinical oncology

authors： Kagimoto A,Tsutani Y,Izaki Y,Handa Y,Mimae T,Miyata Y,Okada M

更新日期：2020-04-07 00:00:00

abstract：:The hematogenous metastases of colon cancer have primarily been explained by the cascade hypothesis based on the cadaveric study. However, we experienced several cases with isolated lung metastasis. The metastatic patterns of a total of 982 patients with colon cancer who underwent surgery were reviewed. The incidence ...

journal_title：Japanese journal of clinical oncology

authors： Sadahiro S,Suzuki T,Tanaka A,Okada K,Kamata H

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:To characterize surgical invasiveness and morbidity and to verify therapeutic efficacy, we reviewed perioperative and postoperative courses and therapeutic outcomes of patients who underwent retroperitoneal lymph node dissection (RPLND) for testicular germ cell cancers. METHODS:The study included 31 patients...

journal_title：Japanese journal of clinical oncology

authors： Tanaka T,Kitamura H,Kunishima Y,Takahashi S,Takahashi A,Masumori N,Itoh N,Tsukamoto T

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Patients suffering from hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT) generally have a poor prognosis. We therefore conducted a prospective pilot trial of combined transcatheter arterial chemoembolization (TACE) and local radiotherapy (RT) for PVTT in unresectable HCC. The aim of the ...

journal_title：Japanese journal of clinical oncology

authors： Yamada K,Soejima T,Sugimoto K,Mayahara H,Izaki K,Sasaki R,Maruta T,Matsumoto S,Hirota S,Sugimura K

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:This retrospective study aimed to evaluate the efficacy of a 3.6-mg dose of pegfilgrastim for primary prophylaxis in Japanese breast cancer patients receiving dose-dense chemotherapy. METHODS:Patients treated with adjuvant or neoadjuvant chemotherapy for early-stage breast cancer at the Tokyo-West Tokushuka...

journal_title：Japanese journal of clinical oncology

authors： Mizuno Y,Fuchikami H,Takeda N,Iwai M,Sato K

更新日期：2017-01-01 00:00:00

abstract：:Australia ranks highly internationally for cancer control, in part because cancer registries provide comprehensive national incidence and mortality and other cancer data annually. This has facilitated short- and long-term planning over the last quarter of a century. For example, male death rates from lung cancer in Au...

journal_title：Japanese journal of clinical oncology

authors： Burton RC

更新日期：2002-03-01 00:00:00

abstract：Background:Stathmin has been found to be involved in malignant tumors; the aim of this study was to investigate the relationship between serum stathmin and clinico-pathological features of lung cancer. Methods:In three lung cancer cell lines, stathmin expression and its secretion level in the supernatant were examined...

journal_title：Japanese journal of clinical oncology

authors： Biaoxue R,Hua L,Tian F,Wenlong G

更新日期：2017-04-01 00:00:00

abstract：:Recent time trends (1979-1987) and geographical distributions in mortalities from subsites of cancers of the hepato-biliary-pancreatic system have been investigated on the basis of the vital statistics of Japan. The corrected age-adjusted mortality rates (CAAMRs) were calculated to eliminate the influence of the propo...

journal_title：Japanese journal of clinical oncology

authors： Kato I,Kuroishi T,Tominaga S

更新日期：1990-09-01 00:00:00

abstract：:Cancer is already a well-recognized global phenomenon. The traditional approaches to cancer therapy have been surgery, radiotherapy and chemotherapy. These modalities have shown considerable promise and presently form cornerstones of management of most malignancies. However, these conventional approaches have associat...

journal_title：Japanese journal of clinical oncology

authors： Munshi A,Ni LH,Tiwana MS

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:The purpose of this study is to clarify the efficacy and toxicity of hyperfractionated radiation therapy (RT) for patients with nasopharyngeal cancer (NPC). METHODS:Twenty-two patients with NPC treated at our hospital between April 1994 and December 2002 were the subjects of this study. They received hyperfr...

journal_title：Japanese journal of clinical oncology

authors： Isobe K,Uno T,Kawakami H,Ueno N,Aruga T,Yasuda S,Hanazawa T,Okamoto Y,Ito H,Shigematsu N

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Vital dye-guided sentinel node biopsy is affordable in most hospitals, but may be of limited accuracy in identifying all sentinel nodes. Leaving sentinel nodes in the axilla may result in a false nodal staging of breast carcinomas. METHODS:From a series of 112 successful sentinel lymph node biopsies with Pa...

journal_title：Japanese journal of clinical oncology

authors： Cserni G,Rajtár M,Boross G

更新日期：2000-06-01 00:00:00

abstract：OBJECTIVE:Study aims include determination of nationwide structural characteristics of radiation oncology facilities, types of radiation therapy equipment, availability of human resources and trends and comparisons with previous surveys. METHODS:An annual nationwide survey was conducted to collect the statistics of in...

journal_title：Japanese journal of clinical oncology

authors： Ji YH,Jung H,Yang K,Cho CK,Yoo SY,Yoo HJ,Kim KB,Kim MS

更新日期：2010-05-01 00:00:00

abstract：:Advanced esophageal cancer patients with extensive lymph node metastases show extremely poor prognosis and the long-term outcome is poorer with the involvement of more lymph nodes. We report here a long-surviving case of advanced esophageal cancer with histologically 34 lymph node metastases, in which surgical resecti...

journal_title：Japanese journal of clinical oncology

authors： Shigemitsu K,Naomoto Y,Shirakawa Y,Haisa M,Gunduz M,Tanaka N

更新日期：2002-08-01 00:00:00

abstract：:Adenoid basal carcinoma of the uterine cervix is rare and its cell origin is still obscure. We report a case of adenoid basal carcinoma of the uterine cervix discovered incidentally in a 69-year-old woman who had been hysterectomized due to endometrial adenocarcinoma of the uterine corpus. Histologically, small round-...

journal_title：Japanese journal of clinical oncology

authors： Senzaki H,Osaki T,Uemura Y,Kiyozuka Y,Ogura E,Okamura A,Tsubura A

更新日期：1997-12-01 00:00:00

abstract：:Adult extrarenal nephroblastomas (Wilms' tumor) are extremely rare tumors. They show a higher incidence of non-seminomatous elements and these so-called 'teratoid' Wilms' tumors are suggested to be of germ cell origin. To date, however, the number of reported cases with gonadal teratoma containing nephroblastoma is ve...

journal_title：Japanese journal of clinical oncology

authors： Keskin S,Ekenel M,Başaran M,Aksu C,Kiliçaslan I,Tunç M,Bavbek S

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:Although cigarette smoking is considered as an important risk factor for esophageal cancer, the magnitude of the association might be varied among geographic areas. Therefore, we reviewed epidemiologic studies on the association between cigarette smoking and esophageal cancer among the Japanese population. M...

journal_title：Japanese journal of clinical oncology

authors： Oze I,Matsuo K,Ito H,Wakai K,Nagata C,Mizoue T,Tanaka K,Tsuji I,Tamakoshi A,Sasazuki S,Inoue M,Tsugane S,Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan.

更新日期：2012-01-01 00:00:00

abstract：:We reviewed 1074 surgically treated patients with biliary tract cancer (gallbladder 564, bile duct 510) in Niigata prefecture in the five-year period from 1982 to 1986. Analyses of regional distributions revealed the incidence of gallbladder cancer to be highest in the Ka-etsu district (northern part of prefecture) an...

journal_title：Japanese journal of clinical oncology

authors： Kato K,Akai S

更新日期：1990-03-01 00:00:00

abstract：:K-ras mutation is the most common oncogenic alteration in various human cancers including colorectal carcinomas. Point mutations have the potential to activate the K-ras gene if they occur in the critical coding sequences. Almost all of these mutations have been localized in codons 12, 13 and 61. We report a case of c...

journal_title：Japanese journal of clinical oncology

authors： Miyakura Y,Sugano K,Fukayama N,Konishi F,Nagai H

更新日期：2002-06-01 00:00:00