Concurrent chemoradiotherapy for squamous cell carcinoma of thoracic esophagus: feasibility and outcome of large regional field and high-dose external beam boost irradiation.

abstract：:The Lugano classification was published in 2014 to form the basis for revising the recommendations regarding anatomic staging and evaluation of disease before and after therapy. This staging system was adopted by the eighth edition of the Cancer Staging Manual of the American Joint Committee on Cancer. In this review,...

journal_title：Japanese journal of clinical oncology

authors： Munakata W,Terauchi T,Maruyama D,Nagai H

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Chromosomal numerical abnormality (CNA) is a characteristic of breast cancer as with other common solid cancers. Multiple mammary carcinomas are also sometimes encountered in the ipsilateral breast. Deciding whether they are multicentric (arising independently) or multifocal (of the same origin) has been a c...

journal_title：Japanese journal of clinical oncology

authors： Nakamura R,Song JP,Isogaki J,Kitayama Y,Sugimura H

更新日期：2003-09-01 00:00:00

abstract：:The occurrence of multiple primary cancers in the aerodigestive tract is a well known phenomenon that has been explained by the concept of 'field carcinogenesis'. Metachronous or synchronous esophageal cancer has usually been identified in patients with head and neck cancer, gastric cancer or colon cancer. The inciden...

journal_title：Japanese journal of clinical oncology

authors： Naomoto Y,Haisa M,Yamatsuji T,Shirakawa Y,Muramatsu T,Isozaki H,Kamikawa Y,Tanaka N

更新日期：1999-07-01 00:00:00

abstract：:The characteristics of early gastric cancer detected by gastric mass survey were examined. The progress of the screening test using the indirect X-ray examination and the tendency toward reduction in mortality from stomach cancer were evaluated. In 1981 the number of examinees in the gastric mass surveys amounted to o...

journal_title：Japanese journal of clinical oncology

authors： Hisamichi S,Sugawara N

更新日期：1984-06-01 00:00:00

abstract：:Eight cultured cell lines were established from human small cell lung cancers. Every cell line showed the morphological and biochemical characteristics of small cell cancer. Changes in cell characteristics were observed in many of these cell lines when culture conditions were changed: "oat cell type" changed to "inter...

journal_title：Japanese journal of clinical oncology

authors： Terasaki T,Shimosato Y,Nakajima T,Tsumuraya M,Morinaga S,Hirohashi S,Yamaguchi K,Kato K,Ichinose H,Nagatsu T

更新日期：1986-09-01 00:00:00

abstract：:Radical cystectomy with lymphadenectomy is the gold standard for treatment of invasive bladder cancer. However, the treatment alone does not always provide a satisfactory result for the disease extending outside the bladder. In this review we discuss several clinical issues in the diagnosis and treatment of this invas...

journal_title：Japanese journal of clinical oncology

authors： Tsukamoto T,Kitamura H,Takahashi A,Masumori N

更新日期：2004-06-01 00:00:00

abstract：:Of the patients with colorectal cancer, there are some with hereditary disorders such as familial polyposis coli, Gardner's syndrome, Turcot's syndrome, and cancer family syndrome in which colorectal adenocarcinoma develops at a significantly high frequency, and these hereditary diseases are very important and interes...

journal_title：Japanese journal of clinical oncology

authors： Ushio K

更新日期：1985-04-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to evaluate patient-related parameters that determine ovarian cyst formation in women using tamoxifen for breast cancer. METHODS:A retrospective review of tamoxifen-treated women with breast cancer who were followed up in the outpatient clinic at Ankara Oncology Hospital between...

journal_title：Japanese journal of clinical oncology

authors： Metindir J,Aslan S,Bilir G

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVES:To examine the association between local recurrence and distant metastasis or disease-specific survival and identify independent factor predictors for local recurrence. METHODS:We identified a study population of 146 consecutive patients treated surgically for invasive bladder cancer at our institution betw...

journal_title：Japanese journal of clinical oncology

authors： Ide H,Kikuchi E,Miyajima A,Nakagawa K,Ohigashi T,Nakashima J,Oya M

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the risk factors for sentinel lymph node metastasis and validate the value of the Memorial Sloan-Kettering Cancer Center nomogram for the prediction of sentinel lymph node metastasis in breast cancer patients. METHODS:A sentinel lymph node biopsy database containing 1227 consecutive breast cancer...

journal_title：Japanese journal of clinical oncology

authors： Qiu PF,Liu JJ,Wang YS,Yang GR,Liu YB,Sun X,Wang CJ,Zhang ZP

更新日期：2012-11-01 00:00:00

abstract：:The risk of a person developing a second primary cancer was evaluated in 1,215 patients with laryngeal cancer at the National Cancer Center Hospital. Overall, 92 (8.2%) of the male patients and 5 (5.7%) of the female patients developed a second cancer, compared with 83.0 and 3.7, respectively, expected on the basis of...

journal_title：Japanese journal of clinical oncology

authors： Kobayashi Y,Arimoto H,Ono I,Watanabe S

更新日期：1990-06-01 00:00:00

abstract：:Irinotecan chloride (CPT-11) is a new semi-synthetic camptothecin analogue which has encouraging antitumor activity against various malignancies. The major and unique toxicity of CPT-11 is diarrhea. Cardiovascular toxicity is rare and has not been found in clinical trials performed in Japan except for a very few cases...

journal_title：Japanese journal of clinical oncology

authors： Miya T,Fujikawa R,Fukushima J,Nogami H,Koshiishi Y,Goya T

更新日期：1998-11-01 00:00:00

abstract：:A double blind study to compare the efficacy of oral UFT (400 mg Tegafur (FT) plus 896 mg uracil/day) with that of oral FT (800 mg/day) on advanced breast cancer was performed between November, 1986, and November, 1989. Sixty patients were registered for the trial and fifty-six cases were evaluated (28 for UFT and 28 ...

journal_title：Japanese journal of clinical oncology

authors： Tashiro H,Nomura Y,Ohsaki A

更新日期：1994-08-01 00:00:00

abstract：Background:Few studies have simultaneously collected quantitative data regarding the positive and negative effects of participating in post-bereavement surveys. Methods:We conducted a cross-sectional postal questionnaire survey in October 2013. Potential participants were caregivers for family members who had died in ...

journal_title：Japanese journal of clinical oncology

authors： Miyashita M,Aoyama M,Yoshida S,Yamada Y,Abe M,Yanagihara K,Shirado A,Shutoh M,Okamoto Y,Hamano J,Miyamoto A,Nakahata M

更新日期：2018-02-01 00:00:00

abstract：:There have been no reports describing acute exacerbations of idiopathic pulmonary fibrosis after particle radiotherapy for non-small cell lung cancer. The present study describes the case of a 76-year-old Japanese man with squamous cell carcinoma of the lung that relapsed in the left upper lobe 1 year after right uppe...

journal_title：Japanese journal of clinical oncology

authors： Nagano T,Kotani Y,Fujii O,Demizu Y,Niwa Y,Ohno Y,Nishio W,Itoh T,Murakami M,Nishimura Y

更新日期：2012-10-01 00:00:00

abstract：:Twenty-six patients with advanced bronchogenic adenocarcinoma or large cell carcinoma were treated by combination chemotherapy consisting of Ftorafur, adriamycin and mitomycin C (FAM II). The patients had not received prior chemotherapy and were not eligible for radiotherapy and surgery. The overall response rate was ...

journal_title：Japanese journal of clinical oncology

authors： Salvati F,Cruciani AR,De Marinis A,Nunziati F,Portalone L

更新日期：1984-03-01 00:00:00

abstract：:Chemoradiation is potentially curative for esophageal cancer in various stages, but local failure is a major problem. The present case was a 49-year-old male diagnosed with advanced esophageal cancer with an esophago-bronchial fistula and lymph node metastasis. Histological diagnosis by biopsy was adenosquamous cell c...

journal_title：Japanese journal of clinical oncology

authors： Morihiro M,Boku N,Ohtsu A,Miyamoto S,Ishikura S

更新日期：2002-02-01 00:00:00

abstract：:A 63-year-old man was admitted to the National Cancer Center Hospital on December 20, 1983 for a close examination of the abnormal shadows found in chest roentgenograms. Chest radiographs showed a massive right pleural effusion, a large tumor in the right hilar region and swelling of the left hilar nodes. Transcutaneo...

journal_title：Japanese journal of clinical oncology

authors： Akiba T,Saijo N,Miyamoto K,Sakurai M,Tamura T,Sasaki Y,Eguchi K,Shinkai T,Uei Y,Fujiwara Y

更新日期：1987-06-01 00:00:00

abstract：Introduction:Since June 2005, the University Hospital Medical Information Network-Clinical Trial Registry (UMIN-CTR) has been an International Committee of Medical Journal Editors (ICMJE)-approved clinical trial registry in Japan. The number of clinical trials registered in the UMIN-CTR has increased annually. To date,...

journal_title：Japanese journal of clinical oncology

authors： Ochi N,Kawahara T,Nagasaki Y,Nakagawa N,Yamagishi T,Umemura S,Honda Y,Nakanishi H,Yamane H,Takigawa N

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Cytokeratins (CKs) 19 and 20 have been used as targets for detecting cancer cells. We attempted to detect circulating cancer cells in patients with gastric cancer using a high-sensitivity reverse transcriptase-polymerase chain reaction (RT-PCR) assay for CK transcripts. METHODS:RT-PCR for CK 19 and CK 20 wa...

journal_title：Japanese journal of clinical oncology

authors： Majima T,Ichikura T,Takayama E,Chochi K,Mochizuki H

更新日期：2000-11-01 00:00:00

abstract：OBJECTIVE:There have been no previous studies about consultation of the bereaved who have lost a loved one to cancer and ask for medical help. The aim of this study was to investigate their basic characteristics and their psychiatric disorders. METHODS:A retrospective study using clinical and background data obtained ...

journal_title：Japanese journal of clinical oncology

authors： Ishida M,Onishi H,Wada M,Tada Y,Ito H,Narabayashi M,Sasaki Y,Nomura S,Uchitomi Y

更新日期：2011-03-01 00:00:00

abstract：:This study was conducted to assess, by continuous exposure, the inhibitory effects of rH-TNF and rH-IFN-alpha, -beta and -gamma, either alone or in combination, on the colony formations of human lung cancer cell lines. The cell lines tested were PC-7 and PC-9 (adenocarcinoma), PC-10 (squamous cell carcinoma) and PC-13...

journal_title：Japanese journal of clinical oncology

authors： Hong WS,Jett JR,Sasaki Y,Takahashi H,Nakano H,Nakagawa K,Hoshi A,Saijo N

更新日期：1987-03-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to assess the efficacy and toxicity of the combination of paclitaxel and nedaplatin as a first-line chemotherapy for patients with advanced esophageal cancer. METHODS:Patients with advanced esophageal cancer received 175 mg/m(2) of paclitaxel over a 3 h infusion, followed by nedapla...

journal_title：Japanese journal of clinical oncology

authors： Cao W,Xu C,Lou G,Jiang J,Zhao S,Geng M,Xi W,Li H,Jin Y

更新日期：2009-09-01 00:00:00

abstract：:A randomized Phase II/III trial commenced in Japan in December 2013. Carboplatin plus etoposide is the current standard treatment for elderly extensive-disease small-cell lung cancer. The purpose of this study is to confirm the superiority of carboplatin plus irinotecan in terms of overall survival over carboplatin pl...

journal_title：Japanese journal of clinical oncology

authors： Eba J,Shimokawa T,Nakamura K,Shibata T,Misumi Y,Okamoto H,Yamamoto N,Ohe Y,Lung Cancer Study Group of the Japan Clinical Oncology Group.

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Intensity-modulated radiotherapy (IMRT) using the simultaneous integrated boost (SIB) method was designed for treating malignant gliomas. The purpose of this study was to investigate feasibility of this treatment. METHODS:Between December 2000 and November 2002, six patients with malignant gliomas were enro...

journal_title：Japanese journal of clinical oncology

authors： Suzuki M,Nakamatsu K,Kanamori S,Okumra M,Uchiyama T,Akai F,Nishimura Y

更新日期：2003-06-01 00:00:00

abstract：:Advanced esophageal cancer patients with extensive lymph node metastases show extremely poor prognosis and the long-term outcome is poorer with the involvement of more lymph nodes. We report here a long-surviving case of advanced esophageal cancer with histologically 34 lymph node metastases, in which surgical resecti...

journal_title：Japanese journal of clinical oncology

authors： Shigemitsu K,Naomoto Y,Shirakawa Y,Haisa M,Gunduz M,Tanaka N

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Although radiotherapy in combination with endocrinal manipulation has been identified as an effective treatment for patients with high-risk prostate cancer, the optimal dose for locoregional control of prostate cancer in combination with hormonal therapy has not yet been determined. METHODS:The efficacy of ...

journal_title：Japanese journal of clinical oncology

authors： Sasaki T,Nakamura K,Shioyama Y,Ohga S,Urashima Y,Terashima H,Koga H,Naito S,Noma H,Komatsu K,Yamaguchi A,Honda H

更新日期：2004-07-01 00:00:00

abstract：Background:The impact of age as a prognostic factor for patients with colorectal cancer (CRC) remains controversial, possibly due to heterogeneity between studies in terms of patient numbers, percentage of patients undergoing curative resection, percentage of patients receiving neoadjuvant therapy, or failure to adjust...

journal_title：Japanese journal of clinical oncology

authors： Chou CL,Tseng CJ,Shiue YL

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:Second primary malignancies have become the leading cause of death in retinoblastoma survivors. Although osteosarcoma is the most common second malignancy, little is known about its clinical and therapeutic features. METHODS:We retrospectively reviewed a database of patients with retinoblastoma and osteosarc...

journal_title：Japanese journal of clinical oncology

authors： Fujiwara T,Fujiwara M,Numoto K,Ogura K,Yoshida A,Yonemoto T,Suzuki S,Kawai A

更新日期：2015-12-01 00:00:00

abstract：:The prognosis of multiple myeloma was quite poor in the last century, but it has significantly improved with the incorporation of novel agents, immunomodulatory drugs (IMiDs) and proteasome inhibitors. Thalidomide was first developed as a sedative in 1950s, but it was withdrawn from the market because of teratogenicit...

journal_title：Japanese journal of clinical oncology

authors： Abe Y,Ishida T

更新日期：2019-08-01 00:00:00