Revised staging system for malignant lymphoma based on the Lugano classification.

Abstract:

:The Lugano classification was published in 2014 to form the basis for revising the recommendations regarding anatomic staging and evaluation of disease before and after therapy. This staging system was adopted by the eighth edition of the Cancer Staging Manual of the American Joint Committee on Cancer. In this review, we aimed to discuss this updated staging system for malignant lymphomas. The most important change was that fluorodeoxyglucose positron emission tomography/computed tomography became the new standard imaging technique for staging of all fluorodeoxyglucose-avid histologies. Due to the introduction of fluorodeoxyglucose positron emission tomography/computed tomography for staging, the evaluation of not only lymph node involvement but also organ involvement, including liver or spleen, has become simplified. Furthermore, it is possible to eliminate bone marrow biopsies in patients with Hodgkin lymphoma and diffuse large B-cell lymphoma. Although patients were grouped according to the absence (A) or presence (B) of disease-related symptoms based on the previous classification, only the patients with Hodgkin lymphoma need to be assigned the designations A or B in this revision. Hopefully, these revised recommendations will improve patient management and the conduct of clinical trials.

journal_name

Jpn J Clin Oncol

authors

Munakata W,Terauchi T,Maruyama D,Nagai H

doi

10.1093/jjco/hyz111

subject

Has Abstract

pub_date

2019-10-01 00:00:00

pages

895-900

issue

10

eissn

0368-2811

issn

1465-3621

pii

5555767

journal_volume

49

pub_type

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