Successful unrelated cord blood transplantation in Philadelphia chromosome positive acute lymphoblastic leukemia during pulmonary aspergillosis treated by anti-fungal therapy, granulocyte colony-stimulating factor-mobilized granulocytes and surgical resec

abstract：:A review of the present status of adjuvant chemotherapy for gastric cancer in Japan has been made. The single use of mitomycin C (MMC) after curative gastrectomy, a multidrug combination of MMC, 5-fluorouracil (5FU) and cytosine arabinoside (CA) (MFC therapy), and a combination of inductive MFC followed by maintenance...

journal_title：Japanese journal of clinical oncology

authors： Nakajima T

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Giant cell tumor (GCT) of bone is a rare and unpredictable lesion. Its standard treatment has ranged from surgical curettage to wide resection and varying oncological and functional results have been reported. METHODS:A retrospective review of 47 patients (17 males and 30 females) with GCT of bone was perfo...

journal_title：Japanese journal of clinical oncology

authors： Oda Y,Miura H,Tsuneyoshi M,Iwamoto Y

更新日期：1998-05-01 00:00:00

abstract：:Rupture of irradiated arteries in patients with head and neck cancer is an uncommon complication. We present the first case of a pseudoaneurysm of the external carotid artery branch that developed after irradiation of nasopharyngeal carcinoma and was successfully treated by microcoil embolization therapy. Clinicians s...

journal_title：Japanese journal of clinical oncology

authors： Li SH,Hsu SW,Wang SL,Chen HC,Huang CH

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVE:We examined the feasibility of regimen selection for first-line irinotecan, 5-fluorouracil and leucovorin or oxaliplatin, 5-fluorouracil and leucovorin in Japanese patients with advanced colorectal cancer based on UDP-glucuronosyltransferase 1A1 genotype as well as physical status of patients related to diarr...

journal_title：Japanese journal of clinical oncology

authors： Ishida H,Fujita K,Akiyama Y,Sunakawa Y,Yamashita K,Mizuno K,Miwa K,Kawara K,Ichikawa W,Ando Y,Saji S,Sasaki Y

更新日期：2011-05-01 00:00:00

abstract：:A post hoc analysis of interim results from PREVAIL, a Phase III, double-blind, placebo-controlled trial of men with metastatic castration-resistant prostate cancer, demonstrated that the treatment effects, safety and pharmacokinetics of enzalutamide in Japanese patients were generally consistent with those of the ove...

journal_title：Japanese journal of clinical oncology

authors： Kimura G,Ueda T

更新日期：2017-03-01 00:00:00

abstract：:A Phase II study was started in Japan to evaluate the efficacy and safety of concurrent chemoradiotherapy with S-1 plus cisplatin in patients with unresectable locally advanced squamous cell carcinoma of the head and neck. This study began in July 2008, and a total of 45 patients will be accrued from 13 institutions w...

journal_title：Japanese journal of clinical oncology

authors： Nakamura K,Tahara M,Kiyota N,Hayashi R,Akimoto T,Fukuda H,Fujii M,Boku N

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:To determine the antitumor activity and toxicity of weekly hepatic arterial infusion (HAI) of 5-fluorouracil (5-FU) for liver metastases from colorectal cancer. In addition, the present study also evaluated the efficacy of second-line chemotherapy after termination of HAI. METHODS:A retrospective study was d...

journal_title：Japanese journal of clinical oncology

authors： Hosokawa A,Yamada Y,Shimada Y,Muro K,Matsumura Y,Fujita S,Akasu T,Moriya Y,Shirao K

更新日期：2003-03-01 00:00:00

abstract：Background:The prevalence and molecular characteristics of defective mismatch repair epithelial ovarian cancers in the Japanese population have scarcely been investigated. Methods:Immunohistochemistry for mismatch repair proteins (MLH1, MSH2, MSH6 and PMS2) was performed in formalin-fixed paraffin-embedded sections pr...

journal_title：Japanese journal of clinical oncology

authors： Tajima Y,Eguchi H,Chika N,Nagai T,Dechamethakun S,Kumamoto K,Tachikawa T,Akagi K,Tamaru JI,Seki H,Okazaki Y,Ishida H

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:In an interim analysis of a Phase II trial in Japanese patients with pancreatic neuroendocrine tumors (panNETs), sunitinib demonstrated antitumor activity with an objective response rate (ORR) of 50% (95% confidence interval [CI], 21-79) and a median progression-free survival (PFS) of 16.8 months (95% CI, 9....

journal_title：Japanese journal of clinical oncology

authors： Ito T,Tori M,Hashigaki S,Kimura N,Sato K,Ohki E,Sawaki A,Okusaka T

更新日期：2019-04-01 00:00:00

abstract：:K-ras mutation is the most common oncogenic alteration in various human cancers including colorectal carcinomas. Point mutations have the potential to activate the K-ras gene if they occur in the critical coding sequences. Almost all of these mutations have been localized in codons 12, 13 and 61. We report a case of c...

journal_title：Japanese journal of clinical oncology

authors： Miyakura Y,Sugano K,Fukayama N,Konishi F,Nagai H

更新日期：2002-06-01 00:00:00

abstract：:Most terminally ill cancer patients in our hospice ward are referred from hospitals for anticancer treatment. For identical terminally ill cancer patients referred from other hospitals, differences in the accuracy and characteristics of the prognostic prediction of survival by oncologists and palliative care physician...

journal_title：Japanese journal of clinical oncology

authors： Urahama N,Sono J,Yoshinaga K

更新日期：2018-07-01 00:00:00

abstract：:Sixty-six patients with carcinoma of the hypopharynx or cervical esophagus received esophageal extraction and primary reconstruction. The methods of reconstruction were free forearm skin tube grafting, free jejunal transplantation and immediate pharyngo-gastrostomy after pull-through esophagectomy. Considering the pos...

journal_title：Japanese journal of clinical oncology

authors： Kato H,Watanabe H,Iizuka T,Ebihara S,Ono I,Terui S,Harii K

更新日期：1987-09-01 00:00:00

abstract：:Among 492 patients with esophageal carcinoma who received resective surgery, 102 survived over 5 years. These 5-year survivors were analyzed according to many factors. Females had a better prognosis than males, and patients without lymph-node metastasis had a better 5-year survival rate than those with it. Ten patient...

journal_title：Japanese journal of clinical oncology

authors： Iizuka T,Kato H,Watanabe H

更新日期：1985-06-01 00:00:00

abstract：:MVP-CAB chemotherapy (methotrexate, vincristine, cisplatin, cyclophosphamide, adriamycin and bleomycin) was administered to 28 patients with high grade, locally-invasive or regional lymph node-involved urothelial cancer as an adjuvant therapy after radical surgery. The median follow-up period of all the evaluated pati...

journal_title：Japanese journal of clinical oncology

authors： Gohji K,Higuchi A,Maruyama S,Minayoshi K,Fujii A,Itoh N,Hasunuma Y,Tanaka H,Izumi T

更新日期：1993-10-01 00:00:00

abstract：:In Japan, lateral lymph node dissection (LLND) is generally performed for the treatment of T3-4 lower rectal carcinoma, and not for T1 lower rectal carcinoma, because of a low positive rate in patients with T1 lesion. We experienced a rare case of lateral pelvic lymph node recurrence after total mesorectal resection f...

journal_title：Japanese journal of clinical oncology

authors： Hara J,Yamamoto S,Fujita S,Akasu T,Moriya Y

更新日期：2008-04-01 00:00:00

abstract：:Due to the rapid aging of Japan's population, clinical research focusing on older patients with cancer is urgently needed. The Japan Clinical Oncology Group (JCOG) has conducted several such clinical trials, but there has been no formal policy for geriatric research. We have therefore established a JCOG policy for ger...

journal_title：Japanese journal of clinical oncology

authors： Mizutani T,Nakamura K,Fukuda H,Ogawa A,Hamaguchi T,Nagashima F,Geriatric Study Committee\/Japan Clinical Oncology Group.

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:Abiraterone acetate has been approved in >70 countries for chemotherapy-naïve metastatic castration-resistant prostate cancer patients. Efficacy and safety of abiraterone acetate (1000 mg/once daily) with prednisolone (5 mg/twice daily) in chemotherapy-naïve Japanese patients with metastatic castration-resist...

journal_title：Japanese journal of clinical oncology

authors： Matsubara N,Uemura H,Satoh T,Suzuki H,Nishiyama T,Uemura H,Hashine K,Imanaka K,Ozono S,Akaza H

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:To clarify the clinical outcomes of stereotactic body radiotherapy for colorectal cancer-derived bone metastases and identify factors predicting treatment failure. METHODS:Patients treated with stereotactic body radiotherapy for bone metastases from colorectal cancer between September 2013 and June 2019 were...

journal_title：Japanese journal of clinical oncology

authors： Ito K,Yamaguchi T,Ogawa H,Nakajima Y,Karasawa K

更新日期：2020-12-16 00:00:00

abstract：OBJECTIVE:Alpha-fetoprotein (AFP) is an important tumor marker for non-seminomatous germ cell tumors (NSGCTs) that greatly affects diagnosis and the evaluations of therapy and therapeutic policy. However, it is sometimes very difficult to make the distinction between tumors and falsely elevated AFP levels due to benign...

journal_title：Japanese journal of clinical oncology

authors： Kamoto T,Satomura S,Yoshiki T,Okada Y,Henmi F,Nishiyama H,Kobayashi T,Terai A,Habuchi T,Ogawa O

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:In a tumor, increased deubiquitination of cyclins by a protein gene product gene, PGP9.5, could contribute to the uncontrolled growth of somatic cells that is a hallmark of cancer. We hypothesized that PGP9.5 may be expressed in tumors of patients with non-small cell lung cancer (NSCLC). METHODS:Expression ...

journal_title：Japanese journal of clinical oncology

authors： Sasaki H,Yukiue H,Moriyama S,Kobayashi Y,Nakashima Y,Kaji M,Fukai I,Kiriyama M,Yamakawa Y,Fujii Y

更新日期：2001-11-01 00:00:00

abstract：:The Lugano classification was published in 2014 to form the basis for revising the recommendations regarding anatomic staging and evaluation of disease before and after therapy. This staging system was adopted by the eighth edition of the Cancer Staging Manual of the American Joint Committee on Cancer. In this review,...

journal_title：Japanese journal of clinical oncology

authors： Munakata W,Terauchi T,Maruyama D,Nagai H

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Second primary head and neck cancers after endoscopic resection of esophageal squamous cell carcinoma adversely affect patients' outcomes and the quality of life; however, an adequate surveillance schedule remains unclear. METHODS:We analyzed 330 patients with early esophageal squamous cell carcinoma who un...

journal_title：Japanese journal of clinical oncology

authors： Shinozaki T,Katada C,Shiga K,Asakage T,Yokoyama T,Yano T,Oda I,Shimizu Y,Takemura K,Ishikawa H,Yokoyama A,Muto M

更新日期：2020-09-28 00:00:00

abstract：BACKGROUND:There have been few reports of sarcoid reaction in the regional lymph nodes associated with lung cancer. The purpose of this study was to analyze the surgical results of lung cancer with sarcoid reaction. METHODS:Of 1733 lung cancer patients undergoing surgical treatment in our institute from 1990 to 2004, ...

journal_title：Japanese journal of clinical oncology

authors： Tomimaru Y,Higashiyama M,Okami J,Oda K,Takami K,Kodama K,Tsukamoto Y

更新日期：2007-02-01 00:00:00

abstract：:Carcinoid tumors located in the minor duodenal papilla are extremely rare, with only a few cases reported in the literature. Herein, we report the case of a 71-year-old man with a 12-mm carcinoid tumor at the minor duodenal papilla with lymph node metastases. Multidetector-row computed tomography with contrast enhance...

journal_title：Japanese journal of clinical oncology

authors： Fukami Y,Kurumiya Y,Mizuno K,Sekoguchi E,Kobayashi S,Ito A,Tomida A,Onishi S,Shirotsuki R,Okubo K,Narita M

更新日期：2013-01-01 00:00:00

abstract：:Some cancer patients suddenly develop severe, excruciating pain that requires rapid management using opioid medication. This study aimed to evaluate the effectiveness of rapid titration using oxycodone injection. Study subjects were advanced cancer patients who experienced severe pain (numeric rating scale ≥7) and nee...

journal_title：Japanese journal of clinical oncology

authors： Nakajima N

更新日期：2019-12-18 00:00:00

abstract：:Immunoperoxidase staining for human keratin proteins was performed cytologically on samples from 90 patients with malignant tumors, and histologically on samples from 164 patients with malignant tumors. At the cytological level, almost all tumor cells not only in squamous cell carcinoma but also in nonsquamous cell ca...

journal_title：Japanese journal of clinical oncology

authors： Yagi Y,Imamura Y,Saku T,Shimotsu T,Hatae M,Yagi S

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVE:Second opinion is a common phenomenon in many health systems, especially in the care of patients with cancer. However, it is not clear whether second opinion seeking should be promoted or discouraged and how second opinion services and policies can be better formalized to maximize the benefits and minimize th...

journal_title：Japanese journal of clinical oncology

authors： Shin DW,Cho J,Yang HK,Kim SY,Mok HK,Lee H,Park SM,Huh JS,Ryu J,Park JH

更新日期：2016-05-01 00:00:00

abstract：:Five cases of recurrent cervical carcinoma with sites of recurrence restricted to the pelvis were treated by intra-arterial infusion of oncostatics via the bilateral internal iliac arteries. One tip of the catheter was positioned in the internal iliac artery, proximal and close to the superior glutea artery, through t...

journal_title：Japanese journal of clinical oncology

authors： Kawagoe K,Iijima S,Sasaki J

更新日期：1983-12-01 00:00:00

abstract：:New drug delivery systems for cis-diamminedichloroplatinum (CDDP) incorporated into vehicles, such as polymethylmethacrylate (PMMA), fibrin glue (F.G.), alpha-tricalciumphosphate (TCP) and ethylenevinyleacetate copolymer (Polymer) were examined using a rat osteosarcoma model. The materials containing CDDP were directl...

journal_title：Japanese journal of clinical oncology

authors： Miura S,Mii Y,Miyauchi Y,Ohgushi H,Morishita T,Hohnoki K,Aoki M,Tamai S,Konishi Y

更新日期：1995-06-01 00:00:00

abstract：OBJECTIVE:Laminin-332, a marker of epithelial-mesenchymal transition, is composed of a heterotrimer of α3, β3 and γ2 chains that regulates cell adhesion and migration. This study aimed to disclose the respective clinical significance of laminin β3 immunoexpression in colorectal cancer as a prognostic factor and a predi...

journal_title：Japanese journal of clinical oncology

authors： Fukazawa S,Shinto E,Tsuda H,Ueno H,Shikina A,Kajiwara Y,Yamamoto J,Hase K

更新日期：2015-06-01 00:00:00