Prognostic factors and prognostic staging system for small cell lung cancer.

abstract：OBJECTIVE:Breast cancer is a heterogeneous disease. The aim of this prospective study, in which fluorescence in situ hybridization was used to determine human epidermal growth factor receptor 2 status in primary breast cancers and in the lymph node metastases, was to verify the stability of human epidermal growth facto...

journal_title：Japanese journal of clinical oncology

authors： Aoyama K,Kamio T,Nishikawa T,Kameoka S

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVE:Despite an increase in the number of Japanese patients with pancreatic neuroendocrine neoplasms, long-term outcomes and prognostic factors, especially for those with advanced disease, remain unclear. METHODS:We retrospectively reviewed the medical records of 78 patients with unresectable pancreatic neuroendo...

journal_title：Japanese journal of clinical oncology

authors： Lee L,Igarashi H,Fujimori N,Hijioka M,Kawabe K,Oda Y,Jensen RT,Ito T

更新日期：2015-12-01 00:00:00

abstract：:Some cancer patients suddenly develop severe, excruciating pain that requires rapid management using opioid medication. This study aimed to evaluate the effectiveness of rapid titration using oxycodone injection. Study subjects were advanced cancer patients who experienced severe pain (numeric rating scale ≥7) and nee...

journal_title：Japanese journal of clinical oncology

authors： Nakajima N

更新日期：2019-12-18 00:00:00

abstract：OBJECTIVE:Overweight and obesity, indicated as increased body mass index, are associated with the risk of some cancers. We carried out a meta-analysis on published cohort and case-control studies to assess the strength of association between body mass index and gastric cancer. METHODS:Relevant studies were identified ...

journal_title：Japanese journal of clinical oncology

authors： Lin XJ,Wang CP,Liu XD,Yan KK,Li S,Bao HH,Zhao LY,Liu X

更新日期：2014-09-01 00:00:00

abstract：Objective:This study aims to reveal the present situation of changes in physical appearance induced by treatment, the effects of these changes on social activities, and support from medical staff in male cancer patients. Methods:A questionnaire survey was administered to 949 male patients (response rate: 90.1%) visiti...

journal_title：Japanese journal of clinical oncology

authors： Nozawa K,Tomita M,Takahashi E,Toma S,Arai Y,Takahashi M

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Giant cell tumor (GCT) of bone is a rare and unpredictable lesion. Its standard treatment has ranged from surgical curettage to wide resection and varying oncological and functional results have been reported. METHODS:A retrospective review of 47 patients (17 males and 30 females) with GCT of bone was perfo...

journal_title：Japanese journal of clinical oncology

authors： Oda Y,Miura H,Tsuneyoshi M,Iwamoto Y

更新日期：1998-05-01 00:00:00

abstract：:This is a review regarding the current therapeutic strategies in the management of multiple myeloma. Due to the introduction of several new effective therapeutic agents, multiple myeloma is one of the most active and changing fields in clinical oncology. Multiple myeloma is caused by the expansion of monoclonal plasma...

journal_title：Japanese journal of clinical oncology

authors： Suzuki K

更新日期：2013-02-01 00:00:00

abstract：:Myxoid liposarcoma can frequently metastasize to extrapulmonary sites. We present two cases of myxoid liposarcoma metastatic to the epidural space. Both patients complained of back pain, but plain radiography revealed no abnormality. MR imaging clearly demonstrated metastatic tumors in the epidural space, but no invol...

journal_title：Japanese journal of clinical oncology

authors： Ogose A,Hotta T,Inoue Y,Sakata S,Takano R,Yamamura S

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVE:Low-dose-rate (LDR) brachytherapy is an effective treatment for tongue cancer. However, little is known about the biological mechanism underlying this therapy, characterized by delivery of continuous exposures of LDR irradiation. It is reported that lower microvessel density (MVD), lower Ki-67 index or higher...

journal_title：Japanese journal of clinical oncology

authors： Sakata K,Someya M,Nagakura H,Nakata K,Oouchi A,Takagi M,Hareyama M

更新日期：2008-06-01 00:00:00

abstract：:The "Criteria for Evaluating the Efficacy of Chemotherapy/Radiation Therapy in the Treatment of Gastric Cancer" are now widely used in Japan. To assess the validity of the criteria, the relation between the antitumor effect evaluated by the criteria and the survival of patients with gastric cancer was analyzed. The su...

journal_title：Japanese journal of clinical oncology

authors： Kiyohashi A,Kurihara M,Yoshida S,Ohkubo T,Suga S

更新日期：1993-02-01 00:00:00

abstract：:An asymptomatic 11-year-old Japanese boy with an endodermal sinus (yolk sac) tumor of the anterior mediastinum was successfully treated with cisplatinum-based combination chemotherapy and subsequent surgical excision. The patient is alive and in good health 60 months from diagnosis. ...

journal_title：Japanese journal of clinical oncology

authors： Seki Y,Ishida I

更新日期：1991-12-01 00:00:00

abstract：:In Japan, lateral lymph node dissection (LLND) is generally performed for the treatment of T3-4 lower rectal carcinoma, and not for T1 lower rectal carcinoma, because of a low positive rate in patients with T1 lesion. We experienced a rare case of lateral pelvic lymph node recurrence after total mesorectal resection f...

journal_title：Japanese journal of clinical oncology

authors： Hara J,Yamamoto S,Fujita S,Akasu T,Moriya Y

更新日期：2008-04-01 00:00:00

abstract：:Seventy metastatic breast adenocarcinoma patients, pretreated with standard hormonotherapy or chemotherapy, received continuous UFT at 10 mg/kg/day, orally, for at least two months. There were one complete response (1.5%), 12 partial responses (17%), one minor response and 37 disease stabilizations. The median duratio...

journal_title：Japanese journal of clinical oncology

authors： Daniels M,Díaz-Rubio E,Guillem V,Montero JM,García-Conde J,Estapé J,Martín M,Herranz C,Ordoñez A,Galán A

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVE:The purpose of the present study was to obtain preliminary findings regarding psychiatric disorders and background characteristics among Japanese family members of cancer patients. METHODS:We investigated the psychiatric diagnosis and background factors of family members of cancer patients by analyzing the c...

journal_title：Japanese journal of clinical oncology

authors： Akechi T,Akizuki N,Okamura M,Shimizu K,Oba A,Ito T,Yoshikawa E,Nakano T,Inagaki M,Uchitomi Y

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVE:After approval of bevacizumab in Japan, post-marketing surveillance studies reported on safety. However, few reports have shown the efficacy of bevacizumab as used in daily practice. We evaluated the efficacy and safety of bevacizumab for metastatic colorectal cancer patients in daily practice. METHODS:All u...

journal_title：Japanese journal of clinical oncology

authors： Sogabe S,Komatsu Y,Yuki S,Kusumi T,Hatanaka K,Nakamura M,Kato T,Miyagishima T,Hosokawa A,Iwanaga I,Sakata Y,Asaka M

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:The majority of patients with localized and some cases of locally advanced prostate cancer undergo radical prostatectomy. However, radical prostatectomy cannot always be selected for those patients. In this situation, primary hormone therapy is an alternative treatment option. We have designed a prospective ...

journal_title：Japanese journal of clinical oncology

authors： Akaza H,Homma Y,Okada K,Yokoyama M,Moriyama N,Usami M,Hirao Y,Tsushima T,Ohashi Y,Aso Y

更新日期：2000-03-01 00:00:00

abstract：Background:Leiomyosarcoma (LMS) is one of most aggressive mesenchymal malignancies that differentiate towards smooth muscle. The clinical outcome of LMS patients is poor; as such, there is an urgent need for novel therapeutic approaches. Experimental models such as patient-derived cell lines are invaluable tools for pr...

journal_title：Japanese journal of clinical oncology

authors： Sakumoto M,Takahashi M,Oyama R,Takai Y,Kito F,Shiozawa K,Qiao Z,Yoshida A,Endo M,Kawai A,Kondo T

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:The detection of prostate-specific antigen (PSA) molecular forms such as free PSA and PSA-ACT and the use of PSA molecular ratios, especially the percentage of free to total PSA, have been reported to improve the diagnostic accuracy of prostate cancer in the patients with slightly elevated serum PSA values. ...

journal_title：Japanese journal of clinical oncology

authors： Kuriyama M,Uno H,Ueno K,Hamamoto Y,Vihn PQ,Ban Y

更新日期：1999-06-01 00:00:00

abstract：:In order to study the characteristics of lung cancer in smokers and nonsmokers, clinico-epidemiological features of 943 lung cancer patients treated in the Aichi Cancer Center Hospital from 1964-77 were analyzed according to their smoking histories. About 70% of both male and female patients who smoked fell in Group I...

journal_title：Japanese journal of clinical oncology

authors： Shimizu H,Tominaga S,Nishimura M,Urata A

更新日期：1984-12-01 00:00:00

abstract：:Morphometrical analysis was performed on cells of bladder carcinomas taken from patients who had undergone surgery at the National Cancer Center Hospital. Ten cases each of the following groups were compared as to the nuclear area, standard deviation of nuclear areas, cytoplasmic area, and nuclear/cytoplasmic ratio: n...

journal_title：Japanese journal of clinical oncology

authors： Hanai S,Kishi K,Watanabe S,Shimosato Y

更新日期：1985-12-01 00:00:00

abstract：:The efficacy of combination therapy with cis-diammine-dichloroplatinum (II) (CDDP) and o-(chloroacetyl-carbamoyl) fumagillol (AGM-1470) was evaluated experimentally using a transplantable rat osteosarcoma line, previously established in our laboratory, with a high potential for metastasis. Tumor-bearing male Fischer 3...

journal_title：Japanese journal of clinical oncology

authors： Morishita T,Mii Y,Miyauchi Y,Miura S,Honoki K,Aoki M,Kido A,Tamai S,Tsutsumi M,Konishi Y

更新日期：1997-08-01 00:00:00

abstract：:Projecting cancer mortality is fundamental to the process of planning cancer control. Although the prefecture is one of the main units for the implementation and evaluation of cancer control in Japan, a long-term detailed future projection of cancer mortality has not been conducted by prefecture. The main objective of...

journal_title：Japanese journal of clinical oncology

authors： Fukui K,Ito Y,Nakayama T

更新日期：2019-04-01 00:00:00

abstract：:The risk of a person developing a second primary cancer was evaluated in 1,215 patients with laryngeal cancer at the National Cancer Center Hospital. Overall, 92 (8.2%) of the male patients and 5 (5.7%) of the female patients developed a second cancer, compared with 83.0 and 3.7, respectively, expected on the basis of...

journal_title：Japanese journal of clinical oncology

authors： Kobayashi Y,Arimoto H,Ono I,Watanabe S

更新日期：1990-06-01 00:00:00

abstract：:Human lymphoblastoid interferon-alpha was administered intramuscularly at a dose of 5 x 10(6) units/day to 20 metastatic renal cell carcinoma patients. For potentiating the antitumor effect of interferon, cimetidine was also given to them orally at a dose of 800 mg/day. The combination therapy obtained a complete resp...

journal_title：Japanese journal of clinical oncology

authors： Kotake T,Kinouchi T,Saiki S,Kuroda M,Miki T,Kiyohara H,Usami M

更新日期：1991-02-01 00:00:00

abstract：:The PRECIOUS study (UMIN000018202) is being conducted as a multicenter, randomized, open-label Phase III study to determine if retreatment with pertuzumab is more effective than conventional treatment in HER2-positive locally advanced (LA)/metastatic breast cancer (MBC) patients previously treated with pertuzumab, tra...

journal_title：Japanese journal of clinical oncology

authors： Yamamoto Y,Iwata H,Ueno T,Taira N,Kashiwaba M,Takahashi M,Tada H,Tsugawa K,Toyama T,Niikura N,Hara F,Fujisawa T,Yoshinami T,Saji S,Takano T,Masuda N,Morita S,Toi M,Ohno S

更新日期：2018-09-01 00:00:00

abstract：:A case of prostatic phyllodes tumor which developed in a 78-yr-old man is reported. Histologically, the tumor comprised myxomatous and cellular portions with a proliferation of atypical stromal cells. Multinucleated giant cells were occasionally present, but mitoses were rare. Fibroblastic differentiation of the tumor...

journal_title：Japanese journal of clinical oncology

authors： Ito H,Ito M,Mitsuhata N,Tahara E

更新日期：1989-09-01 00:00:00

abstract：:Recent time trends (1979-1987) and geographical distributions in mortalities from subsites of cancers of the hepato-biliary-pancreatic system have been investigated on the basis of the vital statistics of Japan. The corrected age-adjusted mortality rates (CAAMRs) were calculated to eliminate the influence of the propo...

journal_title：Japanese journal of clinical oncology

authors： Kato I,Kuroishi T,Tominaga S

更新日期：1990-09-01 00:00:00

abstract：OBJECTIVE:Fibulin-1 is a member of the fibulin gene family, characterized by tandem arrays of epidermal growth factor-like domains and a C-terminal fibulin-type module. Fibulin-1 plays important roles in a range of cellular functions including morphology, growth, adhesion and mobility. It acts as a tumor suppressor gen...

journal_title：Japanese journal of clinical oncology

authors： Cui Y,Liu J,Yin HB,Liu YF,Liu JH

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the risk factors for sentinel lymph node metastasis and validate the value of the Memorial Sloan-Kettering Cancer Center nomogram for the prediction of sentinel lymph node metastasis in breast cancer patients. METHODS:A sentinel lymph node biopsy database containing 1227 consecutive breast cancer...

journal_title：Japanese journal of clinical oncology

authors： Qiu PF,Liu JJ,Wang YS,Yang GR,Liu YB,Sun X,Wang CJ,Zhang ZP

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:T-stage is an imperfect prognostic indicator for patients with nasopharyngeal carcinoma. We evaluated the effect of extent of intracranial involvement on survival after conventional radiotherapy in patients with Stage T4 nasopharyngeal carcinoma. METHODS:We conducted a retrospective analysis of the results o...

journal_title：Japanese journal of clinical oncology

authors： Hu YC,Chang CH,Chen CH,Ger LP,Liu WS,Lin LC,Leung CM,Chang KC

更新日期：2011-01-01 00:00:00