Psychological distress experienced by families of cancer patients: preliminary findings from psychiatric consultation of a Cancer Center Hospital.

abstract：OBJECTIVE:In Japan, population-based cancer incidence data are reported several years behind the latest year of cancer mortality data. To bridge this gap, we aimed to determine a short-term projection method for cancer incidence. METHODS:Data between 1985 and 2007 were obtained from the population-based cancer registr...

journal_title：Japanese journal of clinical oncology

authors： Katanoda K,Kamo K,Saika K,Matsuda T,Shibata A,Matsuda A,Nishino Y,Hattori M,Soda M,Ioka A,Sobue T,Nishimoto H

更新日期：2014-01-01 00:00:00

abstract：:The frequency of expression and localization of cripto-1 (CR-1), amphiregulin (AR), transforming growth factor alpha (TGF alpha), epidermal growth factor receptor (EGFR) and erbB-2 were examined by immunohistochemistry in 45 carcinomas and adjacent non-involved normal colon mucosa. Thirty (66.7%), 24 (53.3%), 23 (51.1...

journal_title：Japanese journal of clinical oncology

authors： Saeki T,Salomon DS,Johnson GR,Gullick WJ,Mandai K,Yamagami K,Moriwaki S,Tanada M,Takashima S,Tahara E

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVE:Limited by sample size, angiosarcoma was rarely studied. We aimed to investigate the characteristics and prognosis of angiosarcoma in the National Cancer Institute's Surveillance, Epidemiology and End Results database. METHODS:Patients who were diagnosed with primary angiosarcoma from 1973 to 2014 were extra...

journal_title：Japanese journal of clinical oncology

authors： Zhang C,Xu G,Liu Z,Xu Y,Lin F,Baklaushev VP,Chekhonin VP,Peltzer K,Mao M,Wang X,Wang G,Zhang C

更新日期：2019-12-27 00:00:00

abstract：:Bone marrow transplantation (BMT) was started in Hokkaido in 1985. In the present report we have reviewed the clinical outcome of patients treated with BMT for hematological diseases in Hokkaido. Fifty-eight allogeneic and 19 autologous transplants were registered by December 1991. The underlying diseases consisted of...

journal_title：Japanese journal of clinical oncology

authors： Hashino S,Imamura M,Kasai M,Higa T,Naohara T,Sakamaki S,Matsunaga T,Kohgo Y,Kohda K,Nakazawa O

更新日期：1993-06-01 00:00:00

abstract：:Eight cultured cell lines were established from human small cell lung cancers. Every cell line showed the morphological and biochemical characteristics of small cell cancer. Changes in cell characteristics were observed in many of these cell lines when culture conditions were changed: "oat cell type" changed to "inter...

journal_title：Japanese journal of clinical oncology

authors： Terasaki T,Shimosato Y,Nakajima T,Tsumuraya M,Morinaga S,Hirohashi S,Yamaguchi K,Kato K,Ichinose H,Nagatsu T

更新日期：1986-09-01 00:00:00

abstract：:A randomized Phase II/III trial commenced in Japan in December 2013. Carboplatin plus etoposide is the current standard treatment for elderly extensive-disease small-cell lung cancer. The purpose of this study is to confirm the superiority of carboplatin plus irinotecan in terms of overall survival over carboplatin pl...

journal_title：Japanese journal of clinical oncology

authors： Eba J,Shimokawa T,Nakamura K,Shibata T,Misumi Y,Okamoto H,Yamamoto N,Ohe Y,Lung Cancer Study Group of the Japan Clinical Oncology Group.

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Second opinion is a common phenomenon in many health systems, especially in the care of patients with cancer. However, it is not clear whether second opinion seeking should be promoted or discouraged and how second opinion services and policies can be better formalized to maximize the benefits and minimize th...

journal_title：Japanese journal of clinical oncology

authors： Shin DW,Cho J,Yang HK,Kim SY,Mok HK,Lee H,Park SM,Huh JS,Ryu J,Park JH

更新日期：2016-05-01 00:00:00

abstract：:During the period 1962-1986, 43 lung cancer patients, 2.3% of the 1,832 patients who underwent pulmonary resections at the National Cancer Center Hospital, Tokyo, had tumors greater than 10 cm in diameter. These 43 cancers were classified postsurgically according to the 1987 guidelines for TNM classification of malign...

journal_title：Japanese journal of clinical oncology

authors： Sano T,Naruke T,Kondo H,Goya T,Tsuchiya R,Suemasu K

更新日期：1990-12-01 00:00:00

abstract：OBJECTIVE:The aim of the present study is to compare the accuracy in using laboratory data or clinical factors, or both, in predicting probability of dying within 7 days of hospice admission in terminal cancer patients. METHODS:We conducted a prospective cohort study of 727 patients with terminal cancer. Three models ...

journal_title：Japanese journal of clinical oncology

authors： Chiang JK,Cheng YH,Koo M,Kao YH,Chen CY

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Angiogenesis is required for growth and metastasis of colorectal cancer (CRC), and several positive regulators of tumor angiogenesis have been identified. Cyclooxygenase-2 (COX-2), known to be elevated in several human cancers, regulates angiogenesis by inducing angiogenic factors. The aim of this study was ...

journal_title：Japanese journal of clinical oncology

authors： Nakamoto RH,Uetake H,Iida S,Kolev YV,Soumaoro LT,Takagi Y,Yasuno M,Sugihara K

更新日期：2007-09-01 00:00:00

abstract：Background:Leiomyosarcoma (LMS) is one of most aggressive mesenchymal malignancies that differentiate towards smooth muscle. The clinical outcome of LMS patients is poor; as such, there is an urgent need for novel therapeutic approaches. Experimental models such as patient-derived cell lines are invaluable tools for pr...

journal_title：Japanese journal of clinical oncology

authors： Sakumoto M,Takahashi M,Oyama R,Takai Y,Kito F,Shiozawa K,Qiao Z,Yoshida A,Endo M,Kawai A,Kondo T

更新日期：2017-10-01 00:00:00

abstract：UNLABELLED:Kidney cancer accounts for approximately 2% of all cancers worldwide, with renal cell carcinoma being the most common form and this report is focused on renal cell carcinoma. Globally, the incidence and mortality rates are increasing by 2-3% per decade. Kidney cancer is less common in Asia compared with the ...

journal_title：Japanese journal of clinical oncology

authors： Naito S,Tomita Y,Rha SY,Uemura H,Oya M,Song HZ,Zhong LH,Wahid MI

更新日期：2010-09-01 00:00:00

abstract：:We present a case of pancreatic leiomyosarcoma with liver metastasis diagnosed by liver tumor biopsy. A 66-year-old man had a pancreatic tumor and hepatic tumors, which were hypoechoic and mixed echoic on ultrasonography, respectively. They were stained in enhanced computed tomography and angiography. A fine needle as...

journal_title：Japanese journal of clinical oncology

authors： Ishii H,Okada S,Okazaki N,Nose H,Yoshimori M,Aoki K,Tsuda H,Hirohashi S

更新日期：1994-02-01 00:00:00

abstract：OBJECTIVE:The optimal management of elderly patients with limited-disease small cell lung cancer (LD-SCLC) has not been established. METHODS:The records of elderly (>or=70 years of age) patients with LD-SCLC who had been treated with etoposide and cisplatin chemotherapy with early concurrent twice-daily thoracic radio...

journal_title：Japanese journal of clinical oncology

authors： Okamoto K,Okamoto I,Takezawa K,Tachibana I,Fukuoka M,Nishimura Y,Nakagawa K

更新日期：2010-01-01 00:00:00

abstract：:We report a 41-year-old woman with a retroperitoneal schwannoma mimicking hepatic tumor in the caudate lobe. Dynamic computed tomography in the early phase showed an enhanced tumor (2.7 cm in diameter) in the Spiegel lobe of the liver, which compressed the inferior vena cava (IVC). We also performed left hepatic angio...

journal_title：Japanese journal of clinical oncology

authors： Nakamura M,Takayama T,Takayasu K,Shimada K,Yamamoto J,Kosuge T,Sakamoto M,Yamasaki S,Shimizu S,Makuuchi M

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Stage III colorectal cancer is an indication for adjuvant chemotherapy; however, there is no definite view on the selection of regimen. If the recurrence can be predicted, it can serve as the indicator of regimen selection. The present study aimed to predict the recurrence of stage III colorectal cancer by c...

journal_title：Japanese journal of clinical oncology

authors： Ishikawa S,Sawayama H,Matsuo A,Uchino R,Honda S,Hirota M,Baba H

更新日期：2019-03-01 00:00:00

abstract：:We retrospectively analyzed the efficacy of chemotherapy in patients whose gastric cancer recurred after adjuvant chemotherapy with S-1. A total of 51 patients were evaluated. Twenty-one patients received S-1-containing chemotherapy as first-line treatment after recurrence [cohort A: S-1 plus cisplatin (n = 10), S-1 m...

journal_title：Japanese journal of clinical oncology

authors： Shitara K,Muro K,Ura T,Takahari D,Yokota T,Sawaki A,Kawai H,Ito S,Yamamura Y

更新日期：2008-11-01 00:00:00

abstract：Background:Gliomas are highly malignant brain tumors. Aberrant activation of NF-κB plays a crucial role in tumor progression. Method:ELISA assay was used to detect NF-κB activity in glimoas cells with different treatments. PPP3CC expression was evaluated by qRT-PCR and western blot assay. Kaplan-Meier analysis estimat...

journal_title：Japanese journal of clinical oncology

authors： Wang H,Zhao S,Chen B,Fu C,Dang Y,Fang P,Wang J,Wang N,Liu L

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:In Japan, concurrent chemoradiotherapy is the standard treatment for unresectable esophageal cancer. The optimal combination of chemotherapeutic agents and radiotherapy dose remains controversial. The present study consists of a phase II trial of a cisplatin (CDDP)/5-fluorouracil (5-FU) infusion with concurr...

journal_title：Japanese journal of clinical oncology

authors： Ishida K,Ando N,Yamamoto S,Ide H,Shinoda M

更新日期：2004-10-01 00:00:00

abstract：OBJECTIVE:To describe changes in Japanese clinical trial regulations after the implementation of the Clinical Trials Act in April 2018. METHODS:First, how to apply multiple regulations after the enforcement of Clinical Trials Act was described. Second, the changes in the number of clinical trials in the National Cance...

journal_title：Japanese journal of clinical oncology

authors： Nakamura K,Shibata T

更新日期：2020-04-07 00:00:00

abstract：:Recurrence or metastasis of cancer has been considered to occur in the last stage of the patient's life. However, the new notions of oligometastases and oligo-recurrence have been proposed and the paradigm shift in the conceptualization of cancer metastasis or cancer recurrence. Oligometastases is the state in which t...

journal_title：Japanese journal of clinical oncology

authors： Niibe Y,Hayakawa K

更新日期：2010-02-01 00:00:00

abstract：:Age-adjusted incidence rates for malignant lymphomas in eastern Asian countries except for the Kyushu district of Japan are lower than those in northern European, North and South American and Oceanian countries. Particularly, the incidence rates for Hodgkin's disease and follicular lymphoma are remarkably low in easte...

journal_title：Japanese journal of clinical oncology

authors： Tajima K,Tominaga S,Suchi T

更新日期：1983-09-01 00:00:00

abstract：:Many psychosocial factors have been reported to influence the duration of survival of breast cancer patients. We have studied how family members, hobbies and habits of the patients may alter their psychosocial status. Female patients with surgically treated breast cancer diagnosed between 1986 and 1995 at the Tochigi ...

journal_title：Japanese journal of clinical oncology

authors： Tominaga K,Andow J,Koyama Y,Numao S,Kurokawa E,Ojima M,Nagai M

更新日期：1998-01-01 00:00:00

abstract：:Nude mice bearing the human oral cavity carcinoma cell line OCC-1, and the lung cancer cell line LC-1, developed a triple paraneoplastic syndrome consisting of hypercalcemia, cachexia and leukocytosis. All of these abnormalities disappeared rapidly after surgical resection of the tumors, suggesting their ectopic humor...

journal_title：Japanese journal of clinical oncology

authors： Tanaka R,Okada M,Kajimura N,Otsubo K,Gyotoku M,Nagasaki K,Ekimoto H,Yamaguchi K

更新日期：1996-04-01 00:00:00

abstract：:Interleukin-12 (IL-12), known to be a strong inducer of interferon-gamma (IFN-gamma), plays a vital role in activating the immune surveillance system against intracellular pathogens and malignant tumors. The authors have found that cancer patients showing marked IFN-gamma induction after inoculation with BCG-CWS (the ...

journal_title：Japanese journal of clinical oncology

authors： Hayashi A,Noda A

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:No risk factor has been confirmed for para-aortic lymph node (PAN) metastasis from gastric cancer. To identify the risk factors and the most frequent route of metastasis to PAN, we analyzed the prospective data from a phase III trial. METHODS:In JCOG9501 comparing D2 and D2 + PAN dissection, 260 patients wi...

journal_title：Japanese journal of clinical oncology

authors： Nomura E,Sasako M,Yamamoto S,Sano T,Tsujinaka T,Kinoshita T,Furukawa H,Shimizu T,Hiratsuka M,Kobayashi O,Kurokawa Y,Tanigawa N,Gastric Cancer Surgical Study Group of the Japan Clinical Oncology Group.

更新日期：2007-06-01 00:00:00

abstract：:In order to determine the significance of androgen receptor (AR) gene mutations for Japanese prostate cancers, we examined the entire coding region, from exon A to H, in 36 primary lesions. Five in stage A, 12 in stage B, six in stage C and 13 in stage D were subjected to PCR-SSCP analysis for genomic DNA and nucleoti...

journal_title：Japanese journal of clinical oncology

authors： Watanabe M,Ushijima T,Shiraishi T,Yatani R,Shimazaki J,Kotake T,Sugimura T,Nagao M

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:Second primary malignancies have become the leading cause of death in retinoblastoma survivors. Although osteosarcoma is the most common second malignancy, little is known about its clinical and therapeutic features. METHODS:We retrospectively reviewed a database of patients with retinoblastoma and osteosarc...

journal_title：Japanese journal of clinical oncology

authors： Fujiwara T,Fujiwara M,Numoto K,Ogura K,Yoshida A,Yonemoto T,Suzuki S,Kawai A

更新日期：2015-12-01 00:00:00

abstract：:This study was conducted to assess, by continuous exposure, the inhibitory effects of rH-TNF and rH-IFN-alpha, -beta and -gamma, either alone or in combination, on the colony formations of human lung cancer cell lines. The cell lines tested were PC-7 and PC-9 (adenocarcinoma), PC-10 (squamous cell carcinoma) and PC-13...

journal_title：Japanese journal of clinical oncology

authors： Hong WS,Jett JR,Sasaki Y,Takahashi H,Nakano H,Nakagawa K,Hoshi A,Saijo N

更新日期：1987-03-01 00:00:00

abstract：:Cancer-associated retinopathy is a rare paraneoplastic syndrome that is often associated with small-cell lung cancer. It is caused by an autoantibody to the 23 kDa photoreceptor protein, recoverin. A small number of reports have described effective treatment for the disease. We report two cases of cancer-associated re...

journal_title：Japanese journal of clinical oncology

authors： Sakamori Y,Kim YH,Okuda C,Togashi Y,Kinose D,Masago K,Mio T,Uji A,Mishima M

更新日期：2011-05-01 00:00:00