Efficacy of CDDP and AGM-1470 chemotherapy against lung metastasis in rat osteosarcoma depends on the timing of combined administration.

abstract：:Chemoradiation is potentially curative for esophageal cancer in various stages, but local failure is a major problem. The present case was a 49-year-old male diagnosed with advanced esophageal cancer with an esophago-bronchial fistula and lymph node metastasis. Histological diagnosis by biopsy was adenosquamous cell c...

journal_title：Japanese journal of clinical oncology

authors： Morihiro M,Boku N,Ohtsu A,Miyamoto S,Ishikura S

更新日期：2002-02-01 00:00:00

abstract：:Myoepithelioma is a rare neoplasm usually occurring in the salivary glands or the mammary glands but also, more rarely, in the thoracic cavity. The diagnosis of myoepithelioma is based on the presence of histological and immunohistochemical characteristics of myoepithelioma, but in unusual locations, the diagnosis is ...

journal_title：Japanese journal of clinical oncology

authors： Habu T,Soh J,Toji T,Shien K,Niman E,Namba K,Sato H,Yamamoto H,Sugimoto S,Yamane M,Toyooka S

更新日期：2018-09-01 00:00:00

abstract：UNLABELLED:Kidney cancer accounts for approximately 2% of all cancers worldwide, with renal cell carcinoma being the most common form and this report is focused on renal cell carcinoma. Globally, the incidence and mortality rates are increasing by 2-3% per decade. Kidney cancer is less common in Asia compared with the ...

journal_title：Japanese journal of clinical oncology

authors： Naito S,Tomita Y,Rha SY,Uemura H,Oya M,Song HZ,Zhong LH,Wahid MI

更新日期：2010-09-01 00:00:00

abstract：:Alendronate, a bisphosphonate compound, lowers serum calcium in patients with cancer-associated hypercalcemia through its inhibitory effect on bone resorption and as a result symptoms associated with hypercalcemia improve. This study was carried out to investigate the effects of alendronate in patients with hypercalce...

journal_title：Japanese journal of clinical oncology

authors： Ohnishi T,Takeda E,Yogita S,Miyake H,Kinoshita T,Terashima Y,Matsumoto T,Tashiro S

更新日期：2000-09-01 00:00:00

abstract：Background:Many patients with colorectal cancer are elderly with competing comorbidities. When constructing nomogram for assessing survival, we should consider the influence of competing risk. A competing-risks nomogram was developed to estimate the probability of death due to colorectal cancer for patients after curat...

journal_title：Japanese journal of clinical oncology

authors： Li J,Li X,Gu J,Ma X,Xue F

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVES:Perinephric fat invasion (PFI) of renal cell carcinoma (RCC) is known to be associated with adverse pathological features and poor prognosis. We analyzed these associations using a sub-group of the RCC registry of The Cancer Registration Committee of the Japanese Urological Association. METHODS:The study co...

journal_title：Japanese journal of clinical oncology

authors： Kume H,Homma Y,Shinohara N,Obara W,Kondo T,Kimura G,Fujimoto H,Nonomura N,Hongo F,Sugiyama T,Takahashi M,Kanayama HO,Fukumori T,Eto M

更新日期：2019-08-01 00:00:00

abstract：:The rise in the incidence of lung cancer has been associated with shifts in histologic distribution. A study was conducted to investigate changes in the cell type distribution in lung cancer in relation to age, sex, and smoking history, based on a retrospective analysis of 10,910 proven cases of lung cancer at the Vet...

journal_title：Japanese journal of clinical oncology

authors： Perng DW,Perng RP,Kuo BI,Chiang SC

更新日期：1996-08-01 00:00:00

abstract：Background:Shorter duration of infusion of monoclonal antibody treatments may reduce treatment burden and improve healthcare resource utilization. Methods:This phase II study recruited Japanese patients with previously untreated CD20+ B-cell non-Hodgkin lymphoma. Patients received intravenous obinutuzumab 1000 mg by r...

journal_title：Japanese journal of clinical oncology

authors： Ohmachi K,Ando K,Kinoshita T,Kumagai K,Hatake K,Ishikawa T,Teshima T,Kato K,Izutsu K,Ueda E,Nakai K,Kuriki H,Tobinai K

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:In Japan, there had been no prospective clinical studies conducted in terms of modified FOLFOX6 + bevacizumab therapy. We performed a post-marketing Phase II multicenter clinical study to examine the efficacy and safety of this regimen as first-line therapy for Japanese patients with advanced/recurrent colore...

journal_title：Japanese journal of clinical oncology

authors： Nishina T,Takano Y,Denda T,Yasui H,Takeda K,Ura T,Esaki T,Okuyama Y,Kondo K,Takahashi Y,Sugiyama Y,Muro K

更新日期：2013-11-01 00:00:00

abstract：:Brachytherapy is an invasive therapy with placement of radiation source into or near the tumor. The difference between planning target volume and clinical target volume is minimal, and the dose out of the tumor reduces rapidly due to the inverse-square law. High-dose-rate brachytherapy enables three-dimensional image ...

journal_title：Japanese journal of clinical oncology

authors： Itami J

更新日期：2020-05-05 00:00:00

abstract：:Five cases of recurrent cervical carcinoma with sites of recurrence restricted to the pelvis were treated by intra-arterial infusion of oncostatics via the bilateral internal iliac arteries. One tip of the catheter was positioned in the internal iliac artery, proximal and close to the superior glutea artery, through t...

journal_title：Japanese journal of clinical oncology

authors： Kawagoe K,Iijima S,Sasaki J

更新日期：1983-12-01 00:00:00

abstract：OBJECTIVE:Oral fluoropyrimidine plus cisplatin is a standard treatment for advanced gastric cancer, but patients with severe peritoneal metastasis often cannot tolerate this regimen. The aim of this study was to assess the feasibility of fluorouracil, l-leucovorin and paclitaxel therapy in such patients. METHODS:In th...

journal_title：Japanese journal of clinical oncology

authors： Iwasa S,Goto M,Yasui H,Nishina T,Takahari D,Nakayama N,Taira K,Kusaba H,Fuse N,Hironaka S,Shimada Y,Nakajima TE

更新日期：2012-09-01 00:00:00

abstract：:Radical cystectomy with lymphadenectomy is the gold standard for treatment of invasive bladder cancer. However, the treatment alone does not always provide a satisfactory result for the disease extending outside the bladder. In this review we discuss several clinical issues in the diagnosis and treatment of this invas...

journal_title：Japanese journal of clinical oncology

authors： Tsukamoto T,Kitamura H,Takahashi A,Masumori N

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Angiosarcoma is an aggressive and malignant neoplasm. Primary hepatic angiosarcoma is extremely rare and accounts for only approximately 5% of all angiosarcomas. Therefore, many doctors do not know enough about this disease; this lack of knowledge motivated us to perform this study. METHODS:We carried out a...

journal_title：Japanese journal of clinical oncology

authors： Zeng D,Cheng J,Gong Z,Chen J,Long H,Zhu B

更新日期：2020-05-05 00:00:00

abstract：OBJECTIVE:To determine the extent of informed decision-making and treatment preference of Korean patients receiving palliative chemotherapy. METHODS:We assessed 138 patients (median age: 58 years; 73% male) with advanced cancer who had received at least one cycle of chemotherapy. General demographic information, the e...

journal_title：Japanese journal of clinical oncology

authors： Kim MK,Lee JL,Hyun MS,Do YR,Song HS,Kim JG,Bae SH,Ryoo HM,Park KU,Lee KH

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:A patient with multiple myeloma developed myelodysplastic syndrome (MDS). Chromosomal analysis performed after the development of MDS revealed monosomy of chromosome 9 in all the meta-phases. We wished to identify the extent of the clone with the chromosomal abnormality originating from MDS clone. METHODS:A...

journal_title：Japanese journal of clinical oncology

authors： Kobayashi Y,Nakayama M,Uemura N,Takeyama K,Tobinai K,Takenaka T,Choi SH,Satoh H,Mori S,Asano S

更新日期：1999-08-01 00:00:00

abstract：:Hepatectomy for liver metastasis from the colo-rectum and other organs was performed in 77 cases at the National Cancer Center Hospital. The operative procedures included every variety of hepatectomy from extended resection as trisegmentectomy to small resection as partial resection. The operative mortality rate was 3...

journal_title：Japanese journal of clinical oncology

authors： Yamasaki S,Hasegawa H,Makuuchi M,Koyama Y,Hojo K,Moriya N

更新日期：1985-03-01 00:00:00

abstract：:The patient was a 9-year-old premenarcheal pediatric female, whose chief complaint was a well-circumscribed palpable right breast mass without nipple discharge. Although the patient had noticed the lump 2 years prior to hospital admission, its size (1.5 × 1.3 cm) had been stable. There was no family history or previou...

journal_title：Japanese journal of clinical oncology

authors： Yorozuya K,Takahashi E,Kousaka J,Mouri Y,Yoshida M,Fujii K,Akizuki M,Nakano S,Fukutomi T,Umemoto Y,Yokoi T,Imai H

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:Phase I oncology trials have raised concerns that patients' 'unrealistic' optimism could compromise the validity of informed consent, and that patients often participate in trials to conform to physicians' or family members' recommendations. We aimed to determine whether patients or families-given the same in...

journal_title：Japanese journal of clinical oncology

authors： Shin DW,Cho J,Kim SY,Yang HK,Cho B,Shin DB,Chun MS,Min YJ,Kim YW,Park JH

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:In an interim analysis of a Phase II trial in Japanese patients with pancreatic neuroendocrine tumors (panNETs), sunitinib demonstrated antitumor activity with an objective response rate (ORR) of 50% (95% confidence interval [CI], 21-79) and a median progression-free survival (PFS) of 16.8 months (95% CI, 9....

journal_title：Japanese journal of clinical oncology

authors： Ito T,Tori M,Hashigaki S,Kimura N,Sato K,Ohki E,Sawaki A,Okusaka T

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:Low-dose-rate (LDR) brachytherapy is an effective treatment for tongue cancer. However, little is known about the biological mechanism underlying this therapy, characterized by delivery of continuous exposures of LDR irradiation. It is reported that lower microvessel density (MVD), lower Ki-67 index or higher...

journal_title：Japanese journal of clinical oncology

authors： Sakata K,Someya M,Nagakura H,Nakata K,Oouchi A,Takagi M,Hareyama M

更新日期：2008-06-01 00:00:00

abstract：:K-ras mutation is the most common oncogenic alteration in various human cancers including colorectal carcinomas. Point mutations have the potential to activate the K-ras gene if they occur in the critical coding sequences. Almost all of these mutations have been localized in codons 12, 13 and 61. We report a case of c...

journal_title：Japanese journal of clinical oncology

authors： Miyakura Y,Sugano K,Fukayama N,Konishi F,Nagai H

更新日期：2002-06-01 00:00:00

abstract：:Cancer-associated retinopathy is a rare paraneoplastic syndrome that is often associated with small-cell lung cancer. It is caused by an autoantibody to the 23 kDa photoreceptor protein, recoverin. A small number of reports have described effective treatment for the disease. We report two cases of cancer-associated re...

journal_title：Japanese journal of clinical oncology

authors： Sakamori Y,Kim YH,Okuda C,Togashi Y,Kinose D,Masago K,Mio T,Uji A,Mishima M

更新日期：2011-05-01 00:00:00

abstract：:We report a 41-year-old woman with a retroperitoneal schwannoma mimicking hepatic tumor in the caudate lobe. Dynamic computed tomography in the early phase showed an enhanced tumor (2.7 cm in diameter) in the Spiegel lobe of the liver, which compressed the inferior vena cava (IVC). We also performed left hepatic angio...

journal_title：Japanese journal of clinical oncology

authors： Nakamura M,Takayama T,Takayasu K,Shimada K,Yamamoto J,Kosuge T,Sakamoto M,Yamasaki S,Shimizu S,Makuuchi M

更新日期：1997-08-01 00:00:00

abstract：:Uterine inversion caused by uterine sarcoma is a rare condition with 12 reported cases to date according to a MEDLINE search. We report two cases of this rare condition. A 71- and a 72-year-old woman presented with uterine sarcomas rapidly extruded into the vagina. In both cases, magnetic resonance imaging (MRI) scans...

journal_title：Japanese journal of clinical oncology

authors： Takano K,Ichikawa Y,Tsunoda H,Nishida M

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:To determine the maximum tolerated dose and recommended dose of cisplatin and docetaxel administered by three consecutive weekly infusions in both non-elderly (< or =74 years) and elderly (> or =75 years) patients, we conducted two independent phase I studies for nonelderly and elderly patients with non-smal...

journal_title：Japanese journal of clinical oncology

authors： Ohe Y,Niho S,Kakinuma R,Kubota K,Matsumoto T,Ohmatsu H,Goto K,Kunitoh H,Saijo N,Nishiwaki Y

更新日期：2001-03-01 00:00:00

abstract：:We retrospectively analyzed the efficacy of chemotherapy in patients whose gastric cancer recurred after adjuvant chemotherapy with S-1. A total of 51 patients were evaluated. Twenty-one patients received S-1-containing chemotherapy as first-line treatment after recurrence [cohort A: S-1 plus cisplatin (n = 10), S-1 m...

journal_title：Japanese journal of clinical oncology

authors： Shitara K,Muro K,Ura T,Takahari D,Yokota T,Sawaki A,Kawai H,Ito S,Yamamura Y

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:It is common that patients with head and neck cancers have secondary malignant neoplasm of esophageal cancer. METHODS:To know the genetic background of the development of these secondary cancers, we performed microsatellite assay at six loci and immunohistochemical analysis on head and neck cancers of eight...

journal_title：Japanese journal of clinical oncology

authors： Kiriu H,Yokozaki H,Yasui W,Ito K,Tahara E

更新日期：1998-12-01 00:00:00

abstract：:A case of primary malignant lymphoma of the skull base is reported. A 62-year-old man was admitted with headache and diplopia. Computed tomography and magnetic resonance imaging showed an abnormal mass in the right parasellar region. The final diagnosis after surgery was primary malignant lymphoma of the skull base. P...

journal_title：Japanese journal of clinical oncology

authors： Oyama H,Nagane M,Shibui S,Nomura K,Mukai K

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:No risk factor has been confirmed for para-aortic lymph node (PAN) metastasis from gastric cancer. To identify the risk factors and the most frequent route of metastasis to PAN, we analyzed the prospective data from a phase III trial. METHODS:In JCOG9501 comparing D2 and D2 + PAN dissection, 260 patients wi...

journal_title：Japanese journal of clinical oncology

authors： Nomura E,Sasako M,Yamamoto S,Sano T,Tsujinaka T,Kinoshita T,Furukawa H,Shimizu T,Hiratsuka M,Kobayashi O,Kurokawa Y,Tanigawa N,Gastric Cancer Surgical Study Group of the Japan Clinical Oncology Group.

更新日期：2007-06-01 00:00:00