Prognostic value of surgical margin status for biochemical recurrence following radical prostatectomy.

abstract：BACKGROUND:Combination of bleomycin, etoposide and cisplatin (BEP) remains the standard chemotherapy for testicular cancer. Since the development of BEP in the 1980s, there has been a considerable advance in supportive therapies, such as granulocyte colony-stimulating-factor and 5-HT3 antagonists. Therefore, we re-eval...

journal_title：Japanese journal of clinical oncology

authors： Kawai K,Ando S,Hinotsu S,Oikawa T,Sekido N,Miyanaga N,Shimazui T,Akaza H

更新日期：2006-07-01 00:00:00

abstract：Background:The prevalence and molecular characteristics of defective mismatch repair epithelial ovarian cancers in the Japanese population have scarcely been investigated. Methods:Immunohistochemistry for mismatch repair proteins (MLH1, MSH2, MSH6 and PMS2) was performed in formalin-fixed paraffin-embedded sections pr...

journal_title：Japanese journal of clinical oncology

authors： Tajima Y,Eguchi H,Chika N,Nagai T,Dechamethakun S,Kumamoto K,Tachikawa T,Akagi K,Tamaru JI,Seki H,Okazaki Y,Ishida H

更新日期：2018-08-01 00:00:00

abstract：:Interstitial pneumonia, especially that due to cytomegalovirus (CMV), is a frequent and serious complication of allogeneic bone marrow transplantation (BMT). The influence of allogeneic BMT on the development of CMV pneumonia was investigated in comparison with that of autologous BMT. Data on 37 patients (23 allotrans...

journal_title：Japanese journal of clinical oncology

authors： Funada H,Harada M,Yoshida T,Hattori K

更新日期：1984-12-01 00:00:00

abstract：:Sarcoma of the hypopharynx has been reported very rarely in the literature, only six cases having been found among all head and neck malignancies reported to SEER (Surveillance, Epidemiology, and End Results) during 1973-1987. We report a 14-year-old boy with a huge malignant soft tissue sarcoma arising from the hypop...

journal_title：Japanese journal of clinical oncology

authors： Lin JC,Hsu CY,Kwan PC,Shen WC,Jan JS,Ho WL

更新日期：1996-06-01 00:00:00

abstract：OBJECTIVE:Communicating the discontinuation of anticancer treatment to patients is a difficult task. The primary aim of this study was to clarify the level of oncologist-reported burden when communicating about discontinuation of an anticancer treatment. The secondary aims were (i) to identify the sources of burden con...

journal_title：Japanese journal of clinical oncology

authors： Otani H,Morita T,Esaki T,Ariyama H,Tsukasa K,Oshima A,Shiraisi K

更新日期：2011-08-01 00:00:00

abstract：Background:Stathmin has been found to be involved in malignant tumors; the aim of this study was to investigate the relationship between serum stathmin and clinico-pathological features of lung cancer. Methods:In three lung cancer cell lines, stathmin expression and its secretion level in the supernatant were examined...

journal_title：Japanese journal of clinical oncology

authors： Biaoxue R,Hua L,Tian F,Wenlong G

更新日期：2017-04-01 00:00:00

abstract：:Chemoradiation is potentially curative for esophageal cancer in various stages, but local failure is a major problem. The present case was a 49-year-old male diagnosed with advanced esophageal cancer with an esophago-bronchial fistula and lymph node metastasis. Histological diagnosis by biopsy was adenosquamous cell c...

journal_title：Japanese journal of clinical oncology

authors： Morihiro M,Boku N,Ohtsu A,Miyamoto S,Ishikura S

更新日期：2002-02-01 00:00:00

abstract：:The patient was a 9-year-old premenarcheal pediatric female, whose chief complaint was a well-circumscribed palpable right breast mass without nipple discharge. Although the patient had noticed the lump 2 years prior to hospital admission, its size (1.5 × 1.3 cm) had been stable. There was no family history or previou...

journal_title：Japanese journal of clinical oncology

authors： Yorozuya K,Takahashi E,Kousaka J,Mouri Y,Yoshida M,Fujii K,Akizuki M,Nakano S,Fukutomi T,Umemoto Y,Yokoi T,Imai H

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Tumor marker-producing germ cell tumors of the central nervous system are malignant and require radiation and/or chemotherapy. Although serum beta-human chorionic gonadotropin (hCG) has been used to monitor the course of treatment, the levels of beta-hCG in the cerebrospinal fluid (CSF) have not been measure...

journal_title：Japanese journal of clinical oncology

authors： Fujimaki T,Mishima K,Asai A,Tabuchi K,Kobayashi M,Suzuki I,Kirino T

更新日期：2000-07-01 00:00:00

abstract：:Cytotoxic effects of mannosamine and free fatty acids on human malignant T-lymphoid cell lines derived from patients with T-cell leukemia were investigated. The combination of mannosamine and an unsaturated fatty acid (oleate or linoleate) produced more striking cytotoxic effects on malignant lymphoid cells than on no...

journal_title：Japanese journal of clinical oncology

authors： Onoda T,Morikawa S,Harada T,Morikawa K

更新日期：1985-09-01 00:00:00

abstract：:Recent studies have suggested that glutathione S-transferase pi (GST-pi) may play a role in determining tumor sensitivities to cytotoxic drugs. In order to better understand the role of this enzyme in chemo- and/or radioresistance of lung cancer cells, we examined whether introduction of GST-pi cDNA into a chemo- and ...

journal_title：Japanese journal of clinical oncology

authors： Miyara H,Hida T,Nishida K,Takahashi T,Sugiura T,Ariyoshi Y,Morishita M,Takahashi T,Ueda R

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:To describe computed tomographic (CT) features of highly enhanced hepatic masses as seen on CT during arterial portography (CTAP) and to survey the varieties of hepatic lesions associated with such findings. METHODS:CTAP files for 400 patients were reviewed, on the basis of which six patients with highly en...

journal_title：Japanese journal of clinical oncology

authors： Onaya H,Itai Y,Satake M,Luo T,Saida Y,Haruno M,Hasebe T,Moriyama N

更新日期：2000-10-01 00:00:00

abstract：:An in vitro monolayer model for cancer invasion was developed, comprising cultured layers of human pleura-derived mesothelial cells (PM cells). The cells were isolated from normal human pleura at autopsy and cultured in RPMI-1640 supplemented with 10% fetal calf serum; they were polygonal in shape, forming a pavement-...

journal_title：Japanese journal of clinical oncology

authors： Horai T,Imamura F,Nakae T,Nakamura S,Mukai M,Shinkai K,Higashino K,Akedo H

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVE:Low-dose-rate (LDR) brachytherapy is an effective treatment for tongue cancer. However, little is known about the biological mechanism underlying this therapy, characterized by delivery of continuous exposures of LDR irradiation. It is reported that lower microvessel density (MVD), lower Ki-67 index or higher...

journal_title：Japanese journal of clinical oncology

authors： Sakata K,Someya M,Nagakura H,Nakata K,Oouchi A,Takagi M,Hareyama M

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:To determine the antitumor activity and toxicity of weekly hepatic arterial infusion (HAI) of 5-fluorouracil (5-FU) for liver metastases from colorectal cancer. In addition, the present study also evaluated the efficacy of second-line chemotherapy after termination of HAI. METHODS:A retrospective study was d...

journal_title：Japanese journal of clinical oncology

authors： Hosokawa A,Yamada Y,Shimada Y,Muro K,Matsumura Y,Fujita S,Akasu T,Moriya Y,Shirao K

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:A patient with multiple myeloma developed myelodysplastic syndrome (MDS). Chromosomal analysis performed after the development of MDS revealed monosomy of chromosome 9 in all the meta-phases. We wished to identify the extent of the clone with the chromosomal abnormality originating from MDS clone. METHODS:A...

journal_title：Japanese journal of clinical oncology

authors： Kobayashi Y,Nakayama M,Uemura N,Takeyama K,Tobinai K,Takenaka T,Choi SH,Satoh H,Mori S,Asano S

更新日期：1999-08-01 00:00:00

abstract：:We retrospectively analyzed the efficacy of chemotherapy in patients whose gastric cancer recurred after adjuvant chemotherapy with S-1. A total of 51 patients were evaluated. Twenty-one patients received S-1-containing chemotherapy as first-line treatment after recurrence [cohort A: S-1 plus cisplatin (n = 10), S-1 m...

journal_title：Japanese journal of clinical oncology

authors： Shitara K,Muro K,Ura T,Takahari D,Yokota T,Sawaki A,Kawai H,Ito S,Yamamura Y

更新日期：2008-11-01 00:00:00

abstract：:Adenoid basal carcinoma of the uterine cervix is rare and its cell origin is still obscure. We report a case of adenoid basal carcinoma of the uterine cervix discovered incidentally in a 69-year-old woman who had been hysterectomized due to endometrial adenocarcinoma of the uterine corpus. Histologically, small round-...

journal_title：Japanese journal of clinical oncology

authors： Senzaki H,Osaki T,Uemura Y,Kiyozuka Y,Ogura E,Okamura A,Tsubura A

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:The study objective was to evaluate the efficacy and toxicity of chemoradiotherapy with 5-fluorouracil (5-FU) plus cisplatin in patients with Stage I esophageal squamous cell carcinoma (ESCC). The primary endpoint was proportion of complete response (%CR). METHODS:Patients with Stage I (T1N0M0) ESCC, aged 20...

journal_title：Japanese journal of clinical oncology

authors： Kato H,Sato A,Fukuda H,Kagami Y,Udagawa H,Togo A,Ando N,Tanaka O,Shinoda M,Yamana H,Ishikura S

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to re-evaluate post-remission therapy outcomes after first remission according to years of patient enrollment in patients with core binding factor acute myeloid leukaemia. METHODS:We conducted a retrospective study on 138 patients aged less than 60 years diagnosed with core bind...

journal_title：Japanese journal of clinical oncology

authors： Shin HJ,Kim HJ,Sohn SK,Min YH,Won JH,Kim I,Yoon HJ,Lee JH,Jo DY,Joo YD,Jung CW,Lee KH,Korean Society of Hematology, AML\/MDS Working Party.,Chung JS,Ahn JS,Kim SJ,Lee JH,Choi SJ,Lee JH,Bae SH,Hong DS,Zang DY,K

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Patterns of cancer incidence and radiotherapy use are similar in Korea and Japan, with differences in radiotherapy infrastructure. METHODS:The authors surveyed the megavoltage machines in 91 radiotherapy centers in Korea and published data in Japan. The number of megavoltage machines per center was used as ...

journal_title：Japanese journal of clinical oncology

authors： Huh SJ,Nishimura T,Park W,Nakamura K

更新日期：2019-12-18 00:00:00

abstract：:A 21-year-old man had undergone central bisegmentectomy of the liver due to fibrolamellar carcinoma (FLC). Twice, 24 and 30 months after the first operation, lymph node metastases were removed. We have reported this case previously and this is the second report of the same case. Forty-two months after the second opera...

journal_title：Japanese journal of clinical oncology

authors： Yamamoto H,Watanabe K,Nagata M,Yano Y,Akai T,Honda I,Watanabe S,Soda H,Matsuzaki O

更新日期：1999-09-01 00:00:00

abstract：Background:The impact of age as a prognostic factor for patients with colorectal cancer (CRC) remains controversial, possibly due to heterogeneity between studies in terms of patient numbers, percentage of patients undergoing curative resection, percentage of patients receiving neoadjuvant therapy, or failure to adjust...

journal_title：Japanese journal of clinical oncology

authors： Chou CL,Tseng CJ,Shiue YL

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:The importance of quality assurance in cancer screening has recently gained increasing attention in Japan. To evaluate and improve quality, checklists and process indicators have been developed. To explore effective methods of enhancing quality in cancer screening, we started a randomized control study of the...

journal_title：Japanese journal of clinical oncology

authors： Machii R,Saika K,Higashi T,Aoki A,Hamashima C,Saito H

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:The natural history and posttherapeutic outcome of adenomatous hyperplasia and early hepatocellular carcinoma have rarely been analyzed. METHODS:Fifty-three hepatic tumors diagnosed as adenomatous hyperplasia or early hepatocellular carcinoma and followed up for more than 6 months and 141 patients with sing...

journal_title：Japanese journal of clinical oncology

authors： Sakamoto M,Hirohashi S

更新日期：1998-10-01 00:00:00

abstract：:Rupture of irradiated arteries in patients with head and neck cancer is an uncommon complication. We present the first case of a pseudoaneurysm of the external carotid artery branch that developed after irradiation of nasopharyngeal carcinoma and was successfully treated by microcoil embolization therapy. Clinicians s...

journal_title：Japanese journal of clinical oncology

authors： Li SH,Hsu SW,Wang SL,Chen HC,Huang CH

更新日期：2007-04-01 00:00:00

abstract：:Squamous cell carcinoma of the head and neck is characterized by an immunosuppressive environment and evades immune responses through multiple resistance mechanisms. A breakthrough in cancer immunotherapy employing immune checkpoint inhibitors has evolved into a number of clinical trials with antibodies against progra...

journal_title：Japanese journal of clinical oncology

authors： Yokota T,Homma A,Kiyota N,Tahara M,Hanai N,Asakage T,Matsuura K,Ogawa T,Saito Y,Sano D,Kodaira T,Motegi A,Yasuda K,Takahashi S,Tanaka K,Onoe T,Okano S,Imamura Y,Ariizumi Y,Hayashi R,Japan Clinical Oncology Group (

更新日期：2020-09-28 00:00:00

abstract：OBJECTIVE:The purpose of this study is to clarify the efficacy and toxicity of hyperfractionated radiation therapy (RT) for patients with nasopharyngeal cancer (NPC). METHODS:Twenty-two patients with NPC treated at our hospital between April 1994 and December 2002 were the subjects of this study. They received hyperfr...

journal_title：Japanese journal of clinical oncology

authors： Isobe K,Uno T,Kawakami H,Ueno N,Aruga T,Yasuda S,Hanazawa T,Okamoto Y,Ito H,Shigematsu N

更新日期：2005-03-01 00:00:00

abstract：:A 63-year-old man was admitted to the National Cancer Center Hospital on December 20, 1983 for a close examination of the abnormal shadows found in chest roentgenograms. Chest radiographs showed a massive right pleural effusion, a large tumor in the right hilar region and swelling of the left hilar nodes. Transcutaneo...

journal_title：Japanese journal of clinical oncology

authors： Akiba T,Saijo N,Miyamoto K,Sakurai M,Tamura T,Sasaki Y,Eguchi K,Shinkai T,Uei Y,Fujiwara Y

更新日期：1987-06-01 00:00:00

abstract：OBJECTIVE:Phase I oncology trials have raised concerns that patients' 'unrealistic' optimism could compromise the validity of informed consent, and that patients often participate in trials to conform to physicians' or family members' recommendations. We aimed to determine whether patients or families-given the same in...

journal_title：Japanese journal of clinical oncology

authors： Shin DW,Cho J,Kim SY,Yang HK,Cho B,Shin DB,Chun MS,Min YJ,Kim YW,Park JH

更新日期：2016-12-01 00:00:00