Post hoc analysis of Japanese patients from the placebo-controlled PREVAIL trial of enzalutamide in patients with chemotherapy-naive, metastatic castration-resistant prostate cancer-updated results.

abstract：BACKGROUND:Intensity-modulated radiotherapy (IMRT) using the simultaneous integrated boost (SIB) method was designed for treating malignant gliomas. The purpose of this study was to investigate feasibility of this treatment. METHODS:Between December 2000 and November 2002, six patients with malignant gliomas were enro...

journal_title：Japanese journal of clinical oncology

authors： Suzuki M,Nakamatsu K,Kanamori S,Okumra M,Uchiyama T,Akai F,Nishimura Y

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Angiosarcoma is an aggressive and malignant neoplasm. Primary hepatic angiosarcoma is extremely rare and accounts for only approximately 5% of all angiosarcomas. Therefore, many doctors do not know enough about this disease; this lack of knowledge motivated us to perform this study. METHODS:We carried out a...

journal_title：Japanese journal of clinical oncology

authors： Zeng D,Cheng J,Gong Z,Chen J,Long H,Zhu B

更新日期：2020-05-05 00:00:00

abstract：BACKGROUND:Patients suffering from hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT) generally have a poor prognosis. We therefore conducted a prospective pilot trial of combined transcatheter arterial chemoembolization (TACE) and local radiotherapy (RT) for PVTT in unresectable HCC. The aim of the ...

journal_title：Japanese journal of clinical oncology

authors： Yamada K,Soejima T,Sugimoto K,Mayahara H,Izaki K,Sasaki R,Maruta T,Matsumoto S,Hirota S,Sugimura K

更新日期：2001-04-01 00:00:00

abstract：:Germline deletion of the 3' portion of the Epithelial Cell Adhesion Molecule (EPCAM) gene located 5' upstream of MutS Homolog 2 (MSH2) is a novel mechanism for its inactivation in Lynch syndrome. However, its contribution in Japanese Lynch syndrome patients is poorly understood. Moreover, somatic events inactivating t...

journal_title：Japanese journal of clinical oncology

authors： Eguchi H,Kumamoto K,Suzuki O,Kohda M,Tada Y,Okazaki Y,Ishida H

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:In Japan, population-based cancer incidence data are reported several years behind the latest year of cancer mortality data. To bridge this gap, we aimed to determine a short-term projection method for cancer incidence. METHODS:Data between 1985 and 2007 were obtained from the population-based cancer registr...

journal_title：Japanese journal of clinical oncology

authors： Katanoda K,Kamo K,Saika K,Matsuda T,Shibata A,Matsuda A,Nishino Y,Hattori M,Soda M,Ioka A,Sobue T,Nishimoto H

更新日期：2014-01-01 00:00:00

abstract：:Immunoperoxidase staining for human keratin proteins was performed cytologically on samples from 90 patients with malignant tumors, and histologically on samples from 164 patients with malignant tumors. At the cytological level, almost all tumor cells not only in squamous cell carcinoma but also in nonsquamous cell ca...

journal_title：Japanese journal of clinical oncology

authors： Yagi Y,Imamura Y,Saku T,Shimotsu T,Hatae M,Yagi S

更新日期：1986-03-01 00:00:00

abstract：:The frequency of expression and localization of cripto-1 (CR-1), amphiregulin (AR), transforming growth factor alpha (TGF alpha), epidermal growth factor receptor (EGFR) and erbB-2 were examined by immunohistochemistry in 45 carcinomas and adjacent non-involved normal colon mucosa. Thirty (66.7%), 24 (53.3%), 23 (51.1...

journal_title：Japanese journal of clinical oncology

authors： Saeki T,Salomon DS,Johnson GR,Gullick WJ,Mandai K,Yamagami K,Moriwaki S,Tanada M,Takashima S,Tahara E

更新日期：1995-12-01 00:00:00

abstract：:Interleukin-12 (IL-12), known to be a strong inducer of interferon-gamma (IFN-gamma), plays a vital role in activating the immune surveillance system against intracellular pathogens and malignant tumors. The authors have found that cancer patients showing marked IFN-gamma induction after inoculation with BCG-CWS (the ...

journal_title：Japanese journal of clinical oncology

authors： Hayashi A,Noda A

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:A retrospective analysis was made to clarify the relationship between prognosis, radiation dose and survival of brain stem gliomas. METHODS:From 1983 to 1995, 22 children with brain stem tumors were treated by radiotherapy in the Veterans General Hospital-Taipei. Twelve patients had pathology proof and the ...

journal_title：Japanese journal of clinical oncology

authors： Liu YM,Shiau CY,Wong TT,Wang LW,Wu LJ,Chi KH,Chen KY,Yen SH

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:Studies have suggested that bevacizumab has shown activity against various pediatric solid tumors. We, therefore, conducted a Phase I study of bevacizumab plus irinotecan in Japanese children with recurrent, progressive or refractory solid tumors. METHODS:The starting dose was bevacizumab 10 mg/kg over 60-90...

journal_title：Japanese journal of clinical oncology

authors： Okada K,Yamasaki K,Tanaka C,Fujisaki H,Osugi Y,Hara J

更新日期：2013-11-01 00:00:00

abstract：:A phase II study of chemoradiotherapy for advanced squamous cell carcinoma of the thoracic esophagus was carried out cooperatively by nine Japanese institutions. Forty-five patients with thoracic advanced squamous cell carcinoma, who had T4 tumor or distant lymph node metastasis (M1(LYM)), were enrolled in the study f...

journal_title：Japanese journal of clinical oncology

authors： Ishida K,Iizuka T,Ando N,Ide H

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:We carried out the present study to investigate the feasibility and effectiveness of concurrent chemoradiotherapy (CT-RT) for postoperative recurrent esophageal cancer, which are, at present, unclear. METHODS:Between 1998 and 2002, 16 patients with postoperative loco-regional recurrence of esophageal cancer...

journal_title：Japanese journal of clinical oncology

authors： Nishimura Y,Koike R,Nakamatsu K,Kanamori S,Suzuki M,Shigeoka H,Shiozaki H

更新日期：2003-07-01 00:00:00

abstract：:Immunohistochemical studies using antisera to keratin and secretory component (SC) and monoclonal antibody against leukocyte common antigen (LCA) were performed on 92 biopsy and autopsy specimens taken from 65 patients with nasopharyngeal carcinoma. Five biopsy specimens from malignant lymphoma of the nasopharynx and ...

journal_title：Japanese journal of clinical oncology

authors： Nomori H,Kameya T,Shimosato Y,Saito H,Ebihara S,Ono I

更新日期：1985-03-01 00:00:00

abstract：:The techniques of aseptic procedures in the laminar airflow room (LAF) were evaluated in 110 adult patients undergoing antileukemic chemotherapy for remission induction. The patients were divided into three groups according to the regimens: Group A, consisting of 20 patients who stayed in the LAF and received the gown...

journal_title：Japanese journal of clinical oncology

authors： Takeo H,Sakurai T,Amaki I

更新日期：1983-01-01 00:00:00

abstract：OBJECTIVE:To investigate the regulative effect of microRNA-338-3p on colorectal carcinoma cell invasion and migration. METHODS:The microRNA-338-3p expression pattern of colorectal carcinoma tissues and cell lines was detected by real-time reverse transcriptase polymerase chain reaction. The protein level of smoothened...

journal_title：Japanese journal of clinical oncology

authors： Xue Q,Sun K,Deng HJ,Lei ST,Dong JQ,Li GX

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:A Phase I/II study of S-1 combined radiation therapy was conducted in patients with Stage II (T2N0) glottic cancer. The purpose of the Phase I study was to identify the maximum tolerated dose, the recommended dose and the dose limiting toxicity. The objectives in the phase II study were to estimate the local ...

journal_title：Japanese journal of clinical oncology

authors： Nakayama M,Hayakawa K,Okamoto M,Niibe Y,Ishiyama H,Kotani S

更新日期：2010-10-01 00:00:00

abstract：:A case of primary malignant lymphoma of the skull base is reported. A 62-year-old man was admitted with headache and diplopia. Computed tomography and magnetic resonance imaging showed an abnormal mass in the right parasellar region. The final diagnosis after surgery was primary malignant lymphoma of the skull base. P...

journal_title：Japanese journal of clinical oncology

authors： Oyama H,Nagane M,Shibui S,Nomura K,Mukai K

更新日期：1992-04-01 00:00:00

abstract：Objective:The prognostic value of metabolic parameters using 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) has not been established for early non-small cell lung cancer (NSCLC). Accordingly, the authors investigated the prognostic value of metabolic parameters in terms of failure ...

journal_title：Japanese journal of clinical oncology

authors： Lee J,Lee M,Koom WS,Kim HJ,Kim WC

更新日期：2018-10-01 00:00:00

abstract：:The positive correlation between smoking and cancer risk is well estimated in sporadic colorectal cancer, whereas little is known with regard to Lynch syndrome-associated colorectal cancer. A total of 118 familial colorectal cancer patients from the Hereditary Nonpolyposis Colorectal Cancer Registry and Genetic Testin...

journal_title：Japanese journal of clinical oncology

authors： Tanakaya K,Furukawa Y,Nakamura Y,Hirata K,Tomita N,Tamura K,Sugano K,Ishioka C,Yoshida T,Ishida H,Watanabe T,Sugihara K,HNPCC registry and genetic testing project of the Japanese Society for Cancer of the Colon and Rectum.,Yama

更新日期：2015-03-01 00:00:00

abstract：PURPOSE:It is difficult to reproduce a brachytherapy measurement because of changes in the rectal shape during inter-fraction. We constructed a multi-purpose brachytherapy phantom (MPBP) and reproduced the same conditions found in actual therapy. We further attempted to apply the measured optimal dose to reduce rectal ...

journal_title：Japanese journal of clinical oncology

authors： Huh H,Kim W,Loh JJ,Lee S,Kim CY,Lee S,Shin D,Shin D,Cho S,Jang J,Lim S,Cho KH,Kwon S,Kim S

更新日期：2007-05-01 00:00:00

abstract：:Bone marrow transplantation (BMT) was started in Hokkaido in 1985. In the present report we have reviewed the clinical outcome of patients treated with BMT for hematological diseases in Hokkaido. Fifty-eight allogeneic and 19 autologous transplants were registered by December 1991. The underlying diseases consisted of...

journal_title：Japanese journal of clinical oncology

authors： Hashino S,Imamura M,Kasai M,Higa T,Naohara T,Sakamaki S,Matsunaga T,Kohgo Y,Kohda K,Nakazawa O

更新日期：1993-06-01 00:00:00

abstract：OBJECTIVE:We conducted a questionnaire survey of oncology specialists to investigate the frequency of administration of different drugs for the management of chemotherapy-induced peripheral neuropathy in Japan in 2015. Our group published Clinical Guidelines for the Management of Chemotherapy-Induced Peripheral Neuropa...

journal_title：Japanese journal of clinical oncology

authors： Hirayama Y,Yoshida Y,Mori M,Tamura K

更新日期：2020-08-04 00:00:00

abstract：BACKGROUND:Programmed death-ligand 1 is an immune modulator that promotes immunosuppression by binding to programmed death-1 of T-lymphocytes. Whereas programmed death-ligand 1 expression has been shown to be associated with the clinical response to anti-programmed death-ligand 1 antibody, the association of tumor prog...

journal_title：Japanese journal of clinical oncology

authors： Inamura K,Yokouchi Y,Sakakibara R,Kobayashi M,Subat S,Ninomiya H,Nagano H,Nomura K,Okumura S,Ishikawa Y

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:This phase I/II study determined the recommended dose of FOLFIRI (irinotecan, infusional 5-fluorouracil and leucovorin) for Japanese patients with advanced colorectal cancer, and evaluated safety at the recommended dose in patients without the UDP-glucuronosyltransferase 1A1*28 allele which caused reduced enz...

journal_title：Japanese journal of clinical oncology

authors： Yamashita K,Nagashima F,Fujita K,Yamamoto W,Endo H,Miya T,Narabayashi M,Kawara K,Akiyama Y,Ando Y,Ando M,Sasaki Y

更新日期：2011-02-01 00:00:00

abstract：:This study is conducted to evaluate the efficacy and safety of preoperative exercise in patients with T1N0/T1N1/T2N0 gastric cancer and metabolic syndrome, which has emerged as a global health care issue. The primary endpoint is an incidence of perioperative complications and the secondary endpoints are weight change,...

journal_title：Japanese journal of clinical oncology

authors： Cho H,Tsuburaya A,Sakamoto J,Morita S,Oba K,Yoshikawa T,Miyajima N,Adjuvant Exercise for General Elective Surgery (AEGES) Study Group.

更新日期：2008-01-01 00:00:00

abstract：:Recent studies have suggested that glutathione S-transferase pi (GST-pi) may play a role in determining tumor sensitivities to cytotoxic drugs. In order to better understand the role of this enzyme in chemo- and/or radioresistance of lung cancer cells, we examined whether introduction of GST-pi cDNA into a chemo- and ...

journal_title：Japanese journal of clinical oncology

authors： Miyara H,Hida T,Nishida K,Takahashi T,Sugiura T,Ariyoshi Y,Morishita M,Takahashi T,Ueda R

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVE:Transcatheter arterial embolization (TAE) with gelatin sponge particles and iodized oil often yields poor results when used to treat unresectable multifocal hepatocellular carcinoma (HCC). The present study retrospectively investigated the utility of a novel combination chemotherapy regimen for treating multi...

journal_title：Japanese journal of clinical oncology

authors： Ishida K,Hirooka M,Hiraoka A,Kumagi T,Uehara T,Hiasa Y,Horiike N,Onji M

更新日期：2008-09-01 00:00:00

abstract：:Primary mesenteric liposarcoma is a rare entity that has been reported only 14 times in English literature. The treatment strategy for mesenteric liposarcoma is, if no distant metastases are detected, surgical resection with a wide surgical margin, often followed by radiation and/or adjuvant chemotherapy for high-risk...

journal_title：Japanese journal of clinical oncology

authors： Ishiguro S,Yamamoto S,Chuman H,Moriya Y

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Regular endoscopic surveillance for Lynch syndrome is reported to reduce colorectal cancer (CRC)-related mortality. However, the appropriate surveillance intervals are still unclear. We evaluated the adequacy of annual colonoscopy and investigated the differences in tumor occurrence rates between individual ...

journal_title：Japanese journal of clinical oncology

authors： Taniguchi F,Tanakaya K,Sugano K,Akagi K,Ishida H,Nagahisa S,Nishimura S,Une Y,Kimura Y,Watanabe M,Utsumi M,Aoki H

更新日期：2020-06-10 00:00:00

abstract：OBJECTIVE:The correlations of serum interleukin-6 and soluble interleukin-6 receptor concentrations with clinicopathological features and survival of patients with colorectal cancer were studied. METHODS:We measured the serum levels of interleukin-6 and soluble interleukin-6 receptor in 99 colorectal cancer patients a...

journal_title：Japanese journal of clinical oncology

authors： Yeh KY,Li YY,Hsieh LL,Lu CH,Chou WC,Liaw CC,Tang RP,Liao SK

更新日期：2010-06-01 00:00:00