Abstract:
OBJECTIVE:The aim of the study was to develop formulations to deliver physiological lipids into skin in an attempt to repair defective barrier function. METHODS:Physiological cholesterol and linoleic acid were incorporated into basic cream and non-ionic cream to prepare skin repair formulations. Homogeneity and storage stability of the developed creams were examined by polarized light microscopy. Ex vivo evaluation was conducted using lipid-deficient skin samples and confocal Raman microspectroscopy. A 7-day in vivo study was performed on volunteers to study the repairing efficacy. RESULTS:Homogeneous texture was seen in the prepared skin repair formulations. The application of the creams led to substantially increased lipid levels compared to the reference in the lipid-deficient skin in ex vivo study. Twice-a-day application of the skin repair creams provided a reinforcement of the skin barrier as transepidermal water loss (TEWL) was significantly decreased. CONCLUSION:The skin repair creams showed excellent efficacy in skin recovery. They have great potentials for treating impaired skin barrier associated with depletion of lipids in stratum corneum.
journal_name
Int J Cosmet Scijournal_title
International journal of cosmetic scienceauthors
Zhang Z,Lukic M,Savic S,Lunter DJdoi
10.1111/ics.12491subject
Has Abstractpub_date
2018-10-01 00:00:00pages
494-501issue
5eissn
0142-5463issn
1468-2494journal_volume
40pub_type
杂志文章abstract:OBJECTIVE:To understand the drivers of body skin discomfort and to validate a new index to assess its severity. This index should be sensitive enough to capture changes in response to treatment. METHODS:Previous consumer studies suggested seven potential main dimensions behind skin discomfort. Four of them refer to se...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12490
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVES:Ageing leads to characteristic changes in the appearance of facial skin. Among these changes, we can distinguish the skin topographic cues (skin sagging and wrinkles), the dark spots and the dark circles around the eyes. Although skin changes are similar in Caucasian and Chinese faces, the age of occurrence ...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12128
更新日期:2014-08-01 00:00:00
abstract::Sun exposure during leisure activity evokes fatigue. We employed the Advanced Trail Making Test (ATMT), a recently developed objective method of evaluating brain function performance used to measure mental fatigue, for objective determination of fatigue development caused by solar exposure to the human body. First, a ...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.0142-5463.2004.00200.x
更新日期:2004-02-01 00:00:00
abstract::Essential oils and certain perfumery raw materials exhibit a wide range of beneficial biological activities. Besides the antimicrobial and antioxidant activity, the anti-inflammatory and anti-irritant effects are most often cited. One specific mode of action is the reduction of the formation of the key mediator prosta...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1468-2494.2007.00392.x
更新日期:2007-10-01 00:00:00
abstract::The hydroglycolic (HG) extract from 70% propylene glycol (PG) extraction of myrobalan fruits showed the most appreciable antioxidant efficiency towards 1,1-diphenyl-2-picrylhydrazyl (DPPH) in comparison to the extracts from 30, 50, 70 and 100% ethyl alcohol (EA), and 30, 50 and 100% PG . Its total polyphenols were als...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1468-2494.2011.00642.x
更新日期:2011-08-01 00:00:00
abstract::It is well established that the evaporation of sweat from the human body surface is the main mechanism by which heat balance is maintained following a rise in body core temperature. Since the introduction of the first brand name antiperspirant in the United States during the early 1900s, antiperspirant products design...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1046/j.1467-2494.2003.00184.x
更新日期:2003-08-01 00:00:00
abstract::Profilaggrin (proFLG) and its processing products are critical to the health and appearance of skin. The recent identification of loss-of-function filaggrin (FLG) mutations as a predisposing factor in ichthyosis vulgaris and atopic dermatitis has lead to a resurgent interest in this enigmatic protein. Here, we review ...
journal_title:International journal of cosmetic science
pub_type: 杂志文章,评审
doi:10.1111/ics.12049
更新日期:2013-10-01 00:00:00
abstract::Synopsis In the last few years a lot of attention has been paid to the development of the in vitro models which would substitute for animals in cutaneous irritancy studies. These models explore either organ or explant cultures using freshly excised skin or serial cultures of isolated skin cells (epidermal keratinocyte...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1992.tb00058.x
更新日期:1992-12-01 00:00:00
abstract:OBJECTIVE:Lipsticks and lip care products may contain saturated hydrocarbons which either stem from mineral oil saturated hydrocarbons (MOSH) or are synthetic, that is polyolefin oligomeric saturated hydrocarbons (POSH). Some of these hydrocarbons are strongly accumulated and form granulomas in human tissues, which pro...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12276
更新日期:2016-04-01 00:00:00
abstract::Many studies have presented stress-strain relationship of human hair, but most of them have been based on an engineering stress-strain curve, which is not a true representation of stress-strain behaviour. In this study, a more accurate 'true' stress-strain curve of human hair was determined by applying optical techniq...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12031
更新日期:2013-06-01 00:00:00
abstract::Synopsis The aim of this work was to evaluate several plant extracts with regard to ultraviolet absorption spectra in view of a possible application as antisolar agents. Liquid and dry extracts of Hamamelis virginiana, Matricaria recutita, Aesculus hippocastanum, Rhamnus purshiana and Cinnamomum zeylanicum were prepar...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1996.tb00140.x
更新日期:1996-06-01 00:00:00
abstract::Various models of reconstructed epidermis already provide useful tools for safety and efficacy assessment of cosmetic products. However, the majority of these in vitro models are composed of keratinocytes only. Recently, the introduction of melanocytes into epidermal reconstructs has considerably enlarged their field ...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1046/j.1467-2494.1999.183571.x
更新日期:1999-02-01 00:00:00
abstract::Acne vulgaris suppresses an individual's self-confidence by causing distress with regard to physical appearance, which affects a significant number of individuals during puberty and is delineated by adolescence. Several treatments have been introduced to decrease the aesthetic and psychological problems caused by acne...
journal_title:International journal of cosmetic science
pub_type: 杂志文章,评审
doi:10.1111/j.1468-2494.2011.00647.x
更新日期:2011-08-01 00:00:00
abstract::The stratum corneum is the outermost layer of the skin. It constitutes a permeability barrier that keeps micro-organisms and toxic agents from entering the skin, while retaining water and electrolytes. In order to preserve its colour and elasticity, the skin needs lipids and water. Certain occlusive products in contac...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.2007.00357.x
更新日期:2007-04-01 00:00:00
abstract::Long cattle tendons were enzymatically disposed of lipoid and accompanying nitrogenous substances. Collagenous hydrolysate of average molecular mass M(a) = 0.830 +/- 1.206 kDa, suitable for application in skin and hair-care preparations, was obtained through hydrolysis by commercial protease (Bacillus subtilis) under ...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1046/j.1467-2494.2002.00151.x
更新日期:2002-10-01 00:00:00
abstract::Kajal and surma are eye cosmetics extensively used in Indian subcontinent. Kajal is prepared by burning of vegetable oil and butter oil while surma by grinding of the stones. High performance liquid chromatography and gas chromatography-mass spectrometry instruments were used for quantification and confirmation of 16 ...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1468-2494.2009.00497.x
更新日期:2009-06-01 00:00:00
abstract::Lecithin has an antioxidative potential that depends directly on the content of phospholipids. Purified lecithin with a higher phospholipid content exerts better antioxidative properties. Furthermore, due to its specific physico-chemical properties, amphiphility in particular, the phospholipid the largest portion of t...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1046/j.1467-2494.1999.181682.x
更新日期:1999-08-01 00:00:00
abstract::Synopsis Glutathione (GSH) plays an important role in cellular protection during ageing. The hair plucking technique is a non-invasive method for the direct biochemical study of keratinocytes. Hair was taken from the suboccipital area of 63 volunteers (men and women whose ages ranged from 13 to 103 years). The results...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1991.tb00555.x
更新日期:1991-06-01 00:00:00
abstract::The addition of water to lipsticks in the form of a water-in-oil emulsion is an attractive opportunity for cosmetics manufacturers to deliver hydrophilic molecules to the consumers, as well as improving the moisturizing properties. In this work, the effect of the emulsifier type and water content on the structural pro...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1468-2494.2010.00624.x
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVE:Axillary wetness represents an unwanted effect of the physiologically vital sweating mechanism, especially when it becomes excessive. Cosmetic products reducing sweat secretion rely on aluminium salts as the active ingredient acting by physically blocking the sweat gland. Driven by the interest to better unde...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12679
更新日期:2020-12-01 00:00:00
abstract::Synopsis A brief review of new techniques of assessing skin irritancy is presented. Some of the difficulties of assessing minor degrees of irritancy are discussed. ...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1979.tb00229.x
更新日期:1979-12-01 00:00:00
abstract::Synopsis The mechanism of colour change during the pigment dispersion process and during powder application to the skin surface was studied by examining the colour extension properties of Yellow. Red, and Black iron oxides in white powder bases. A new measure for the evaluation of the degree of colour extension was de...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1985.tb00391.x
更新日期:1985-02-01 00:00:00
abstract:OBJECTIVE:To study the effects of addition of a redox metal, copper, antioxidants and metal chelators on the formation of free radicals in natural white Caucasian hair subsequently exposed to UV light. Three different methods, electron paramagnetic resonance (EPR), a fluorescent probe for hydroxyl radical formation (te...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12601
更新日期:2020-04-01 00:00:00
abstract:OBJECTIVES:Facial clinical signs and their integration are the basis of perception than others could have from ourselves, noticeably the age they imagine we are. Facial modifications in motion and their objective measurements before and after application of skin regimen are essential to go further in evaluation capacit...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12198
更新日期:2015-06-01 00:00:00
abstract::It is well known that the shelf-life of products containing dihydroxyacetone (DHA) is quite unsatisfactory, and that in this area the adjustment to an acidic pH is the way usually recommended to improve DHA stability. The adoption of this rule, however, is a challenge for the cosmetic chemist not only because of the r...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.2007.00381.x
更新日期:2007-06-01 00:00:00
abstract::Summary The authors studied the combination of Kathon(R) CG and Germall(R) II (0.1%-0.1%) in hydrophilic creams. Their objective was to find an alternative to the use of parabens. Kathon(R) CG was chosen due to its antimicrobial effectiveness and its broad spectrum of activity. It must be indicated, however, that it h...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1987.tb00463.x
更新日期:1987-04-01 00:00:00
abstract::The objective of the study was to compare measurements of skin hydration and of biomechanical properties performed on different zones of face and volar forearm. Two short-term (1 h) and two long-term (3 weeks) studies were conducted with a moisturizing and a firming product, respectively, on groups of female volunteer...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.2006.00352.x
更新日期:2006-12-01 00:00:00
abstract:OBJECTIVE:To investigate the efficacy of 13 antimicrobial substances (11 substances of natural origin and two conventional preservatives as controls) at two concentrations in an o/w cosmetic emulsion. METHODS:Cosmetic formulations were analysed for total aerobic bacterial count and total combined yeast count according...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12461
更新日期:2018-05-05 00:00:00
abstract::Synopsis The viscosity of cosmetic emulsions is of great practical importance and related to their skin feel. To achieve a desirable and constant viscosity is not an easy task because numerous factors must be considered. Based on theoretical considerations a new surfactant, steareth-5-stearate, has been developed. It ...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1991.tb00546.x
更新日期:1991-02-01 00:00:00
abstract::The color and odor of cosmetics have been shown to be crucial for affective states and able to influence autonomic responses. We report an original procedure to measure the effect on subjects of the color and odor of cosmetic products, and to quantify the correlation between objective (psychophysiological recording) a...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.2003.00196.x
更新日期:2003-12-01 00:00:00