Influence of liposomes on the stability of vitamin a incorporated in polyacrylate hydrogel.

Abstract:

:Lecithin has an antioxidative potential that depends directly on the content of phospholipids. Purified lecithin with a higher phospholipid content exerts better antioxidative properties. Furthermore, due to its specific physico-chemical properties, amphiphility in particular, the phospholipid the largest portion of the lecithin lipids, forms enclosed membrane systems (liposomes) in the presence of water. Liposomes encapsulate hydro and liposoluble, pharmacologically and cosmetically active components. The relatively poor stability of vitamin A considerably limits its use in topical preparations. Protection against an oxidation process is the main reason for vitamin A encapsulation in the liposomes made from the purified phospholipid fraction (90% phosphatidyl choline). It increases the vitamin A-palmitate stability against the oxidation process caused by UV radiation. Lecithin used for preparing the liposomes increases vitamin A stability during UV radiation in pure liposome dispersion or liposomes with vitamin A incorporated in polyacrylate gel as a vehicle.

journal_name

Int J Cosmet Sci

authors

Arsić I,Vuleta G

doi

10.1046/j.1467-2494.1999.181682.x

subject

Has Abstract

pub_date

1999-08-01 00:00:00

pages

219-25

issue

4

eissn

0142-5463

issn

1468-2494

pii

ICS181682

journal_volume

21

pub_type

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