Nanosystems for skin hydration: a comparative study.

Abstract:

:The present investigation describes a comparative study for the design of innovative topical formulation for skin hydration. In particular, different colloidal forms based on lipidic components have been produced and characterized. Morphology and dimensional distribution have been investigated by means of electron microscopy and photon correlation spectroscopy. Nanoparticulate systems characterized by different morphology and dimensions depending on production procedures have been obtained, namely cubosomes, nanovesicles, solid lipid nanoparticles and liposomes. Hydration power has been studied by means of a corneometer, measuring the skin electrical capacitance before and after the application of opportunely viscosized nanoparticulate systems. It has been demonstrated that nanovesicle gel displayed a pronounced hydration power with respect to the other nanostructured forms, its hydration effect on skin was 3.5-fold higher, with respect to the untreated area, after 5 min from the application and 1.5-fold higher after 2 h.

journal_name

Int J Cosmet Sci

authors

Esposito E,Drechsler M,Mariani P,Sivieri E,Bozzini R,Montesi L,Menegatti E,Cortesi R

doi

10.1111/j.1467-2494.2007.00362.x

subject

Has Abstract

pub_date

2007-02-01 00:00:00

pages

39-47

issue

1

eissn

0142-5463

issn

1468-2494

pii

ICS362

journal_volume

29

pub_type

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