Abstract:
:Developmental plasticity describes the influence of environmental factors on phenotypic variation. An important mediator of developmental plasticity in many animals is parental care. Here, we examine the consequences of maternal care on offspring after the initial mass provisioning of brood in the small carpenter bee, Ceratina calcarata. Removal of the mother during larval development leads to increased aggression and avoidance in adulthood. This corresponds with changes in expression of over one thousand genes, alternative splicing of hundreds of genes, and significant changes to DNA methylation. We identify genes related to metabolic and neuronal functions that may influence developmental plasticity and aggression. We observe no genome-wide association between differential DNA methylation and differential gene expression or splicing, though indirect relationships may exist between these factors. Our results provide insight into the gene regulatory context of DNA methylation in insects and the molecular avenues through which variation in maternal care influences developmental plasticity.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Arsenault SV,Hunt BG,Rehan SMdoi
10.1038/s41467-018-05903-0subject
Has Abstractpub_date
2018-08-27 00:00:00pages
3468issue
1issn
2041-1723pii
10.1038/s41467-018-05903-0journal_volume
9pub_type
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