Expression and Regulation of Deubiquitinase-Resistant, Unanchored Ubiquitin Chains in Drosophila.

abstract：:Mitochondria-generated reactive oxygen species (mROS) are frequently associated with DNA damage and cell cycle arrest, but physiological increases in mROS serve to regulate specific cell functions. T3 is a major regulator of mROS, including hydrogen peroxide (H2O2). Here we show that exogenous thyroid hormone (T3) adm...

journal_title：Scientific reports

authors： Tan L,Bogush N,Naib H,Perry J,Calvert JW,Martin DIK,Graham RM,Naqvi N,Husain A

更新日期：2019-11-27 00:00:00

abstract：:Recently, a concept of digital metamaterials has been proposed to manipulate field distribution through proper spatial mixtures of digital metamaterial bits. Here, we present a design of 2-bit digitally-controlled coding metasurface that can effectively modulate the scattered electromagnetic wave and realize different...

journal_title：Scientific reports

authors： Huang C,Sun B,Pan W,Cui J,Wu X,Luo X

更新日期：2017-02-08 00:00:00

abstract：:Varroa destructor mites express strong avoidance of the Apis cerana worker brood in the field. The molecular mechanism for this phenomenon remains unknown. We identified a Varroa toxic protein (VTP), which exhibited toxic activity toward A. cerana worker larvae, in the saliva of these mites, and expressed VTP in an Es...

journal_title：Scientific reports

authors： Zhang Y,Han R

更新日期：2018-02-21 00:00:00

abstract：:T helper 17 (Th17) cells not only play critical roles in protecting against bacterial and fungal infections but are also involved in the pathogenesis of autoimmune diseases. The retinoic acid-related orphan receptor (RORγt) is a key transcription factor involved in Th17 cell differentiation through direct transcriptio...

journal_title：Scientific reports

authors： Wu Q,Nie J,Gao Y,Xu P,Sun Q,Yang J,Han L,Chen Z,Wang X,Lv L,Tsun A,Shen J,Li B

更新日期：2015-11-09 00:00:00

abstract：:It is frequently assumed that in the limit of vanishing cooling rate, the glass transition phenomenon becomes a thermodynamic transition at a temperature TK. However, with any finite cooling rate, the system falls out of equilibrium at temperatures near Tg(>TK), implying that the very existence of the putative thermod...

journal_title：Scientific reports

authors： Chakrabarty S,Karmakar S,Dasgupta C

更新日期：2015-07-24 00:00:00

abstract：:Enterobacter aerogenes LU2 was isolated from cow rumen and recognized as a potential succinic acid producer in our previous study. Here, we present the first complete genome sequence of this new, wild strain and report its basic genetic features from a biotechnological perspective. The MinION single-molecule nanopore ...

journal_title：Scientific reports

authors： Szczerba H,Komoń-Janczara E,Krawczyk M,Dudziak K,Nowak A,Kuzdraliński A,Waśko A,Targoński Z

更新日期：2020-02-06 00:00:00

abstract：:Perpendicular magnetization and precise control over the magnetic easy axis in magnetic thin film is necessary for a variety of applications, particularly in magnetic recording media. A strong (111) orientation is successfully achieved in the CoFe2O4 (CFO) thin film at relatively low substrate temperature of 100 °C, w...

journal_title：Scientific reports

authors： Shirsath SE,Liu X,Yasukawa Y,Li S,Morisako A

更新日期：2016-07-20 00:00:00

abstract：:Climate can modulate human health at large spatial scales, but the influence of global, regional, and local environments remains poorly understood, especially for neglected diseases, such as mycoses. In this work, we present the correlation between climatic variables and hospitalizations for mycoses in Brazilian state...

journal_title：Scientific reports

authors： Silva FB,Santos JRN,da Silva LC,Gomes WC,Villis PCM,Gomes EDS,Pinheiro EAD,Azevedo CMPES,Dias RDS,Monteiro CA,Santos JRA

更新日期：2019-05-06 00:00:00

abstract：:The prognostic value and staging category of parotid lymph node (PLN) metastasis in nasopharyngeal carcinoma (NPC) remain unknown. We retrospectively reviewed MRI scans and medical records for 1811 NPC patients who received intensity-modulated radiotherapy. The diagnosis of PLN metastasis was mainly based on MRI follo...

journal_title：Scientific reports

authors： Zhang Y,Li WF,Chen L,Mao YP,Guo R,Zhang F,Peng H,Liu LZ,Li L,Liu Q,Ma J

更新日期：2015-09-08 00:00:00

abstract：:Orbital angular momentum (OAM) multiplexing technique has recently emerged and generated widespread interests since the OAM was discovered as a property of electromagnetic wave and acoustic wave. It was widely acknowledged that OAM multiplexing can achieve very high effective degrees of freedom (EDOF) and improve the ...

journal_title：Scientific reports

authors： Li Z,Qu F,Wei Y,Yang G,Xu W,Xu J

更新日期：2020-03-23 00:00:00

abstract：:The transfer entropy is a well-established measure of information flow, which quantifies directed influence between two stochastic time series and has been shown to be useful in a variety fields of science. Here we introduce the transfer entropy of the backward time series called the backward transfer entropy, and sho...

journal_title：Scientific reports

authors： Ito S

更新日期：2016-11-11 00:00:00

abstract：:Over the last decades, great strides were made in the development of novel implants for the treatment of bone defects. The increasing versatility and complexity of these implant designs request for concurrent advances in means to assess in vivo the course of induced bone formation in preclinical models. Since its disc...

journal_title：Scientific reports

authors： Lienemann PS,Metzger S,Kiveliö AS,Blanc A,Papageorgiou P,Astolfo A,Pinzer BR,Cinelli P,Weber FE,Schibli R,Béhé M,Ehrbar M

更新日期：2015-05-19 00:00:00

abstract：:Non-small cell lung cancer (NSCLC) is the most frequent cause of cancer-related death worldwide. Although many molecular-targeted drugs for NSCLC have been developed in recent years, the 5-year survival rate of patients with NSCLC remains low. Therefore, an improved understanding of the molecular mechanisms underlying...

journal_title：Scientific reports

authors： Hirono T,Jingushi K,Nagata T,Sato M,Minami K,Aoki M,Takeda AH,Umehara T,Egawa H,Nakatsuji Y,Kitae K,Ueda Y,Hase H,Yamamoto M,Shinsato Y,Kawahara K,Furukawa T,Tsujikawa K

更新日期：2019-05-06 00:00:00

abstract：:Follicular bronchiolitis (FB) is a rare interstitial lung disease (ILD) and has been reported in diverse clinical contexts. Six FB patients demonstrated by surgical lung biopsy (SLB) were reviewed between 2009 and 2017 from Nanjing Drum Tower Hospital in China. The average age of subjects was 42 years old (range: 31-5...

journal_title：Scientific reports

authors： Lu J,Ma M,Zhao Q,Meng F,Wang D,Cai H,Cao M

更新日期：2018-05-08 00:00:00

abstract：:Increasing attention is given to personalized tumour therapy, where α-emitters can potentially play an important role. Alpha particles are ideal for localized cell killing because of their high linear energy transfer and short ranges. However, upon the emission of an α particle the daughter nuclide experiences a recoi...

journal_title：Scientific reports

authors： Kruijff RM,Raavé R,Kip A,Molkenboer-Kuenen J,Morgenstern A,Bruchertseifer F,Heskamp S,Denkova AG

更新日期：2019-08-12 00:00:00

abstract：:Reporter gene imaging allows for non-invasive monitoring of molecular processes in living cells, providing insights on the mechanisms underlying pathology and therapy. A lysine-rich protein (LRP) chemical exchange saturation transfer (CEST) MRI reporter gene has previously been developed and used to image tumor cells,...

journal_title：Scientific reports

authors： Perlman O,Ito H,Gilad AA,McMahon MT,Chiocca EA,Nakashima H,Farrar CT

更新日期：2020-11-26 00:00:00

abstract：:Supplementation of cattle diets with n-3-polyunsaturated fatty acids (PUFA) can improve reproductive efficiency. Conversely, short-term fluctuations in feed supply can impact pregnancy establishment. The objectives of this study were to examine the effects of (1) dietary supplementation with n-3-PUFA and (2) post-inse...

journal_title：Scientific reports

authors： Surlis C,Cormican P,Waters SM,Lonergan P,Keogh K,Doyle DN,Kenny DA

更新日期：2020-11-27 00:00:00

abstract：:On an SiO2-patterned c-plane sapphire substrate, GaN domains were grown with their polarity controlled in accordance with the pattern. While N-polar GaN was grown on hexagonally arranged circular openings, Ga-polar GaN was laterally overgrown on mask regions due to polarity inversion occurring at the boundary of the c...

journal_title：Scientific reports

authors： Jang D,Jue M,Kim D,Kim HS,Lee H,Kim C

更新日期：2018-03-07 00:00:00

abstract：:The effect on post-operative outcomes after coronary artery bypass graft (CABG) surgery is not clear. Among 17,812 patients who underwent CABG during October 1,2006-September 28,2012 in any Department of US Veterans Affairs (VA) hospital, we identified 5,968 with available preoperative urine albumin-creatinine ratio (...

journal_title：Scientific reports

authors： George LK,Molnar MZ,Lu JL,Kalantar-Zadeh K,Koshy SK,Kovesdy CP

更新日期：2015-11-09 00:00:00

abstract：:As a fundamental property of pressure-induced amorphization (PIA) in ice and ice-like materials (notably α-quartz), the occurrence of mechanical instability can be related to violation of Born criteria for elasticity. The most outstanding elastic feature of α-quartz before PIA has been experimentally reported to be th...

journal_title：Scientific reports

authors： Dong J,Zhu H,Chen D

更新日期：2015-06-23 00:00:00

abstract：:Fatty infiltration in muscle is often observed in patients with sizable rotator cuff tear (RCT) and is thought to be an irreversible event that significantly compromises muscle plasticity and contraction strength. These changes in the mechanical properties of the affected muscle render surgical repair of RCT highly fo...

journal_title：Scientific reports

authors： Shirasawa H,Matsumura N,Shimoda M,Oki S,Yoda M,Tohmonda T,Kanai Y,Matsumoto M,Nakamura M,Horiuchi K

更新日期：2017-01-31 00:00:00

abstract：:Hormonal changes due to menopause can cause various health problems including weight gain and depressive symptoms. Multiple lines of evidence indicate that oestrogen receptors (ERs) play a major role in postmenopausal obesity and depression. However, little is known regarding the ER subtype-specific effects on obesity...

journal_title：Scientific reports

authors： Sasayama D,Sugiyama N,Yonekubo S,Pawlak A,Murasawa H,Nakamura M,Hayashi M,Ogawa T,Moro M,Washizuka S,Amano N,Hongo K,Ohnota H

更新日期：2017-07-05 00:00:00

abstract：:The structure and function of cellular membranes were sustained by redox-enzymes. We studied the interaction between the oxidative stress caused by excessive accumulation of ZnO-nanoparticles (ZnO-NPs) in plants and the role of redox-enzymes that can alleviate this stress. The crude callus extract from pomegranate, wh...

journal_title：Scientific reports

authors： Farghaly FA,Radi AA,Al-Kahtany FA,Hamada AM

更新日期：2020-11-12 00:00:00

abstract：:Stream microbes that occur in the Mediterranean Basin have been shown to possess heightened sensitivity to intensified water stress attributed to climate change. Here, we investigate the effects of long-term drought (150 days), storms and rewetting (7 days) on the diversity and composition of archaea, bacteria and fun...

journal_title：Scientific reports

authors： Gionchetta G,Romaní AM,Oliva F,Artigas J

更新日期：2019-09-18 00:00:00

abstract：:Despite the quintessential role that music plays in human societies by enabling us to release and share emotions with others, traces of its evolutionary origins in other species remain scarce. Drumming like humans whilst producing music is practically unheard of in our most closely related species, the great apes. Alt...

journal_title：Scientific reports

authors： Dufour V,Poulin N,Charlotte Curé,Sterck EH

更新日期：2015-06-17 00:00:00

abstract：:Myocardial infarction (MI) can result in sympathetic nerve loss in the infarct region. However, the contribution of hypo-innervation to electrophysiological remodeling, independent from MI-induced ischemia and fibrosis, has not been comprehensively investigated. We present a novel mouse model of regional cardiac sympa...

journal_title：Scientific reports

authors： Tapa S,Wang L,Francis Stuart SD,Wang Z,Jiang Y,Habecker BA,Ripplinger CM

更新日期：2020-11-02 00:00:00

abstract：:Cathelicidins are short cationic host defense peptides and play a central role in host innate immune system. Here we identified two novel cathelicidins, Cl-CATH2 and 3, from Columba livia. Evolutionary analysis of avian cathelicidins via phylogenetic tree and Ka/Ks calculations supported the positive selection that pr...

journal_title：Scientific reports

authors： Yu H,Lu Y,Qiao X,Wei L,Fu T,Cai S,Wang C,Liu X,Zhong S,Wang Y

更新日期：2015-07-21 00:00:00

abstract：:Accurate detection of accelerometer non-wear time is crucial for calculating physical activity summary statistics. In this study, we evaluated three epoch-based non-wear algorithms (Hecht, Troiano, and Choi) and one raw-based algorithm (Hees). In addition, we performed a sensitivity analysis to provide insight into th...

journal_title：Scientific reports

authors： Syed S,Morseth B,Hopstock LA,Horsch A

更新日期：2020-04-03 00:00:00

abstract：:In external radiotherapy (RT), the use of flattening filter-free (FFF) radiation beams obtained by removing the flattening filter (FF) in standard linear accelerators is rapidly increasing, and the benefits of clinical use are the issue of research. Advanced treatment techniques have increased the interest in the oper...

journal_title：Scientific reports

authors： Arslan A,Sengul B

更新日期：2020-06-02 00:00:00

abstract：:Although geological and modelling evidence indicate that the last glacial inception in North America was in NE Canada, little is known about the glacial response of the nearby western Greenland Ice Sheet (GIS) during the glacial advance of marine oxygen isotope stage 4 (MIS4). Our multi-proxy study of a marine sedimen...

journal_title：Scientific reports

authors： Seidenkrantz MS,Kuijpers A,Olsen J,Pearce C,Lindblom S,Ploug J,Przybyło P,Snowball I

更新日期：2019-10-30 00:00:00