The Limits of Effective Degrees of Freedom in UCA based Orbital Angular Momentum Multiplexed Communications.

abstract：:Etoposide (ETO) is a commonly used chemotherapeutic drug that inhibits topoisomerase II activity, thereby leading to genotoxicity and cytotoxicity. However, ETO has limited application due to its side effects on normal organs, especially the kidney. Here, we report the mechanism of ETO-induced cytotoxicity progression...

journal_title：Scientific reports

authors： Shin HJ,Kwon HK,Lee JH,Anwar MA,Choi S

更新日期：2016-09-26 00:00:00

abstract：:Tetrandrine (Tet) could enhance the antitumor effect of Paclitaxel (Ptx) by increasing intracellular Reactive Oxygen Species (ROS) levels, which leads to the possibility of co-delivery of both drugs for synergistic antitumor effect. In the current study, we reported an efficient, local therapeutic strategy employing e...

journal_title：Scientific reports

authors： Zhang H,Tian Y,Zhu Z,Xu H,Li X,Zheng D,Sun W

更新日期：2016-05-26 00:00:00

abstract：:In actively deforming regions, crustal deformation is accommodated by earthquakes and through a variety of transient aseismic phenomena. Here, we study the 2010-2014 Pollino (Southern Italy) swarm sequence (main shock M W 5.1) located within the Pollino seismic gap, by analysing the surface deformation derived from Gl...

journal_title：Scientific reports

authors： Cheloni D,D'Agostino N,Selvaggi G,Avallone A,Fornaro G,Giuliani R,Reale D,Sansosti E,Tizzani P

更新日期：2017-04-12 00:00:00

abstract：:Craniofacial muscles drive critical functions in the head, including speech, feeding and expression. Compared with their counterparts in trunk and limbs, craniofacial muscles are of distinct embryonic origins, which might consequently lead to different growth patterns and regenerative potential. In this study, rat lev...

journal_title：Scientific reports

authors： Cheng X,Huang H,Luo X,Shi B,Li J

更新日期：2018-07-13 00:00:00

abstract：:Transcriptional coactivator PGC-1α and its splice variant NT-PGC-1α play crucial roles in regulating cold-induced thermogenesis in brown adipose tissue (BAT). PGC-1α and NT-PGC-1α are highly induced by cold in BAT and subsequently bind to and coactivate many transcription factors to regulate expression of genes involv...

journal_title：Scientific reports

authors： Chang JS,Ghosh S,Newman S,Salbaum JM

更新日期：2018-05-18 00:00:00

abstract：:Fire-induced permafrost degradation is well documented in boreal forests, but the role of fires in initiating thermokarst development in Arctic tundra is less well understood. Here we show that Arctic tundra fires may induce widespread thaw subsidence of permafrost terrain in the first seven years following the distur...

journal_title：Scientific reports

authors： Jones BM,Grosse G,Arp CD,Miller E,Liu L,Hayes DJ,Larsen CF

更新日期：2015-10-29 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Kakar KU,Nawaz Z,Cui Z,Cao P,Jin J,Shu Q,Ren X

更新日期：2020-03-10 00:00:00

abstract：:Ergothioneine (ERG), a unique thiol compound, is suggested to function as an antioxidant and cytoprotectant. Despite several recent attempts to produce ERG using various organisms, its yield was still very low and the costs remained high. Since the level of ERG produced depends strictly on the availability of three di...

journal_title：Scientific reports

authors： Tanaka N,Kawano Y,Satoh Y,Dairi T,Ohtsu I

更新日期：2019-02-13 00:00:00

abstract：:Our study focused on quantifying the alterations of streamflow at a weir site due to the construction of a mini-hydropower plant in the Gurugoda Oya (Sri Lanka), and evaluating the spatial responses of benthic macroinvertebrates to altered flow regime. The HEC-HMS 3.5 model was applied to the Gurugoda Oya sub-catchmen...

journal_title：Scientific reports

authors： Munasinghe DSN,Najim MMM,Quadroni S,Musthafa MM

更新日期：2021-01-12 00:00:00

abstract：:Alternative oxidase (AOX) is a mitochondrial inner-membrane oxidase that accepts electrons directly from ubiquinol and reduces oxygen to water without involving cytochrome-linked electron transport chain. It is highly conserved in many non-vertebrate taxa and may protect cells against hypoxia and oxidative stress. We ...

journal_title：Scientific reports

authors： Liu M,Guo X

更新日期：2017-09-07 00:00:00

abstract：:In situ tissue engineering within a stroke cavity is gradually emerging as a novel therapeutic paradigm. Considering the varied lesion topology within each subject, the placement and distribution of cells within the lesion cavity is challenging. The use of multiple cell types to reconstruct damaged tissue illustrates ...

journal_title：Scientific reports

authors： Nicholls FJ,Ling W,Ferrauto G,Aime S,Modo M

更新日期：2015-09-30 00:00:00

abstract：:Here, water flow inside large radii semi-infinite carbon nanotubes is investigated. Permeable wall taking into account the molecular interactions between water and a nanotube, and the slip boundary condition will be considered. Furthermore, interactions among molecules are approximated by the continuum approximation. ...

journal_title：Scientific reports

authors： Chan Y,Lee SL,Chen W,Zheng L,Shi Y,Ren Y

更新日期：2019-08-20 00:00:00

abstract：:The artificial earthquake of mb 6.1 related to the North Korea's sixth nuclear test occured at Mt. Mantap, North Korea on September 3, 2017. It was reported that a large and complex surface deformation was caused by the event. The surface deformation was composed of expansion of explosions, collapse, compaction and la...

journal_title：Scientific reports

authors： Baek WK,Jung HS,Kim TS

更新日期：2020-10-20 00:00:00

abstract：:Platelet microvesicles (pMVs) are submicron-sized heterogeneous vesicles released upon activation and contain several membrane receptors and proteins (CD41, CD61, CD62, CXCR4, PAR-1, etc.). We have revealed their ability to adhere to the triblock copolymer pluronic-F127 (PF127) and form a platelet microvesicular nanoc...

journal_title：Scientific reports

authors： Chander V,Gangenahalli G

更新日期：2020-01-13 00:00:00

abstract：:In order to study the molecular differences between type 2 diabetes mellitus (T2DM) and T2DM with depression (DD), we aimed to screen the differential expression of lncRNA, mRNA, and circRNA in the blood of patients with T2DM and DD. Based on the self-rating depression scale (SDS), patient health questionnaire 9 (PHQ9...

journal_title：Scientific reports

authors： An T,Zhang J,Ma Y,Lian J,Wu YX,Lv BH,Ma MH,Meng JH,Zhou YT,Zhang ZY,Liu Q,Gao SH,Jiang GJ

更新日期：2019-07-24 00:00:00

abstract：:Data on post stroke outcomes in developing countries are scarce due to uncoordinated healthcare delivery systems. In Malaysia, the national stroke clinical practice guideline does not address transfer of care and longer term post stroke care beyond tertiary care. Hence, post stroke care delivery may be delivered at ei...

journal_title：Scientific reports

authors： Abdul Aziz AF,Ali MF,Yusof MF,Che' Man Z,Sulong S,Aljunid SM

更新日期：2018-12-19 00:00:00

abstract：:Positions of leaves along a stem usually adhere to a genetically determined, species-specific pattern known as a leaf phyllotaxis. We investigated whether the arrangement of lateral secondary veins along primary midveins adhered to a species-specific pattern that resembled an alternate or opposite phyllotaxis. We anal...

journal_title：Scientific reports

authors： Koyama K,Masuda T

更新日期：2018-11-06 00:00:00

abstract：:Link prediction in complex networks aims at predicting the missing links from available datasets which are always incomplete and subject to interfering noises. To obtain high prediction accuracy one should try to complete the missing information and at the same time eliminate the interfering noise from the datasets. G...

journal_title：Scientific reports

authors： Xu X,Liu B,Wu J,Jiao L

更新日期：2017-11-07 00:00:00

abstract：:Developing an effective universal influenza vaccine against influenza virus with highly conserved antigenic epitopes could induce a broad-spectrum immune response to prevent infection. The soluble protein M1 that can induce the M1 specific immune response was first confirmed in our previous study. In this study, we ch...

journal_title：Scientific reports

authors： Liu F,Wang X,Zheng M,Xiong F,Liu X,Zhou L,Tan W,Chen Z

更新日期：2020-03-05 00:00:00

abstract：:We discuss subwavelength-scale semiconductor metal-optic resonators placed on the metal substrate with various top metal plate sizes. Albeit with large optical losses, addition of metal layers converts a leaky semiconductor nano-block into a highly-confined optical cavity. Optically pumped lasing action is observed wi...

journal_title：Scientific reports

authors： Kwon K,You JB,Shim J,Jung Y,Yu K

更新日期：2016-08-23 00:00:00

abstract：:15-lipoxygenase is involved in the generation of specialized pro-resolving lipid mediators that play essential roles in resolution and inflammatory responses. Here, we investigated anti-inflammatory role of Alox15 in skin homeostasis. We demonstrated that knockout (KO) of Alox15 led to hair loss and disrupted the stru...

journal_title：Scientific reports

authors： Kim SN,Akindehin S,Kwon HJ,Son YH,Saha A,Jung YS,Seong JK,Lim KM,Sung JH,Maddipati KR,Lee YH

更新日期：2018-06-11 00:00:00

abstract：:Wide-angle optical systems play a vital role in imaging applications and have been researched for many years. In traditional lenses, attaining a wide field of view (FOV) by using a single optical component is difficult because these lenses have crucial aberrations. In this study, we developed a wide-angle metalens wit...

journal_title：Scientific reports

authors： Fan CY,Lin CP,Su GJ

更新日期：2020-09-24 00:00:00

abstract：:Current medications inadequately treat the symptoms of chronic pain experienced by over 50 million people in the United States, and may come with substantial adverse effects signifying the need to find novel treatments. One novel therapeutic target is the Transient Receptor Potential A1 channel (TRPA1), an ion channel...

journal_title：Scientific reports

authors： Ko MJ,Ganzen LC,Coskun E,Mukadam AA,Leung YF,van Rijn RM

更新日期：2019-02-20 00:00:00

abstract：:microRNAs regulate the expression of over 60% of protein coding genes by targeting their mRNAs to AGO2-containing complexes in the cytoplasm and promoting their translational inhibition and/or degradation. There is little evidence so far for microRNA-mediated regulation of other classes of non-coding RNAs. Here we rep...

journal_title：Scientific reports

authors： Leucci E,Patella F,Waage J,Holmstrøm K,Lindow M,Porse B,Kauppinen S,Lund AH

更新日期：2013-01-01 00:00:00

abstract：:Culture expanded mesenchymal stromal cells (MSCs) are being extensively studied for therapeutic applications, including treatment of graft-versus-host disease, osteogenesis imperfecta and for enhancing engraftment of hematopoietic stem cells after transplantation. Thus far, clinical trials have shown that the therapeu...

journal_title：Scientific reports

authors： Dorland YL,Cornelissen AS,Kuijk C,Tol S,Hoogenboezem M,van Buul JD,Nolte MA,Voermans C,Huveneers S

更新日期：2019-10-07 00:00:00

abstract：:Mitofusins are large transmembrane GTPases of the dynamin-related protein family, and are required for the tethering and fusion of mitochondrial outer membranes. Their full-length structures remain unknown, which is a limiting factor in the study of outer membrane fusion. We investigated the structure and dynamics of ...

journal_title：Scientific reports

authors： De Vecchis D,Cavellini L,Baaden M,Hénin J,Cohen MM,Taly A

更新日期：2017-08-31 00:00:00

abstract：:The purpose of this work is to make a case for epidemiological models with fractional exponent in the contribution of sub-populations to the incidence rate. More specifically, we question the standard assumption in the literature on epidemiological models, where the incidence rate dictating propagation of infections i...

journal_title：Scientific reports

authors： Taghvaei A,Georgiou TT,Norton L,Tannenbaum A

更新日期：2020-11-30 00:00:00

abstract：:Osteopontin (OPN) is involved in cell proliferation, migration, inflammation, and tumor progression in various tissues. OPN induces stemness by interacting with CD44, but the functional relevance of OPN-mediated interferon (IFN) signaling and hepatitis C virus (HCV) replication in stem cell populations remains unclear...

journal_title：Scientific reports

authors： Shirasaki T,Honda M,Yamashita T,Nio K,Shimakami T,Shimizu R,Nakasyo S,Murai K,Shirasaki N,Okada H,Sakai Y,Sato T,Suzuki T,Yoshioka K,Kaneko S

更新日期：2018-09-03 00:00:00

abstract：:Aldosterone antagonists slow the progression of chronic kidney disease (CKD), but their use is limited by hyperkalemia, especially when associated with RAS inhibitors. We examined the renoprotective effects of Ly, a novel non-steroidal mineralocorticoid receptor (MR) blocker, through two experimental protocols: In Pro...

journal_title：Scientific reports

authors： Fujihara CK,Kowala MC,Breyer MD,Sena CR,Rodrigues MV,Arias SCA,Fanelli C,Malheiros DM,Jadhav PK,Montrose-Rafizadeh C,Krieger JE,Zatz R

更新日期：2017-08-11 00:00:00

abstract：:Biofilm formation in flea gut is important for flea-borne transmission of Yersinia pestis. There are enhancing factors (HmsHFRS, HmsCDE, and HmsT) and inhibiting one (HmsP) for Yersinia pestis biofilm formation. The RcsAB regulatory complex acts as a repressor of Yesinia biofilm formation, and adaptive pseudogenizatio...

journal_title：Scientific reports

authors： Fang N,Yang H,Fang H,Liu L,Zhang Y,Wang L,Han Y,Zhou D,Yang R

更新日期：2015-04-01 00:00:00