The osteopontin-CD44 axis in hepatic cancer stem cells regulates IFN signaling and HCV replication.

abstract：:We examined whether blood lead levels (BLLs) were associated with reproductive hormone levels in a cross-sectional study using data from the SPECT-China study. We selected 2286 men and 1571 postmenopausal women without hormone replacement therapy. BLLs, blood cadmium, total testosterone (TT), oestradiol (E2), luteiniz...

journal_title：Scientific reports

authors： Chen C,Wang N,Zhai H,Nie X,Sun H,Han B,Li Q,Chen Y,Cheng J,Xia F,Zhao L,Zheng Y,Shen Z,Lu Y

更新日期：2016-11-29 00:00:00

abstract：:Antimicrobial peptides, produced by innate immune system of hosts in response to invading pathogens, are capable of fighting against a spectrum of bacteria, viruses, fungi, parasites and cancer cells. Here, a recombinant silkworm AMP Bmattacin2 from heterologous expression is studied, indicating a broad spectrum of an...

journal_title：Scientific reports

authors： Li Z,Liu X,Li Y,Lan X,Leung PH,Li J,Li G,Xie M,Han Y,Lin X

更新日期：2016-08-09 00:00:00

abstract：:Infection diagnosis and antibiotic susceptibility testing (AST) are time-consuming and often laborious clinical practices. This paper presents a microwave-microfluidic biosensor for rapid, contactless and non-invasive device for testing the concentration and growth of Escherichia Coli (E. Coli) in medium solutions of ...

journal_title：Scientific reports

authors： Narang R,Mohammadi S,Ashani MM,Sadabadi H,Hejazi H,Zarifi MH,Sanati-Nezhad A

更新日期：2018-10-25 00:00:00

abstract：:Although gut microbiota and early life events are likely involved in the development of irritable bowel syndrome (IBS), it remains unclear how these factors interact in the pathophysiology of IBS. In the present study, using rats subjected to maternal separation (MS) as a model of IBS, we investigated interrelationshi...

journal_title：Scientific reports

authors： Fukui H,Oshima T,Tanaka Y,Oikawa Y,Makizaki Y,Ohno H,Tomita T,Watari J,Miwa H

更新日期：2018-08-17 00:00:00

abstract：:State-of-art quantum key distribution (QKD) systems are performed with several GHz pulse rates, meanwhile privacy amplification (PA) with large scale inputs has to be performed to generate the final secure keys with quantified security. In this paper, we propose a fast Fourier transform (FFT) enhanced high-speed and l...

journal_title：Scientific reports

authors： Tang BY,Liu B,Zhai YP,Wu CQ,Yu WR

更新日期：2019-10-31 00:00:00

abstract：:Small bowel capsule endoscopy (SBCE) and balloon-assisted endoscopy (BAE) have revolutionized the diagnosis and treatment of small bowel bleeding (SBB), allowing access to the small bowel and identification of specific bleeding lesions. However, some patients experience rebleeding after small bowel investigation, and ...

journal_title：Scientific reports

authors： Uchida G,Hirooka Y,Nakamura M,Watanabe O,Yamamura T,Matsushita M,Suhara H,Ishikawa T,Furukawa K,Funasaka K,Ohno E,Kawashima H,Miyahara R,Goto H

更新日期：2018-04-23 00:00:00

abstract：:Amyloid formation is associated with various pathophysiological conditions like Alzheimer's and Parkinson's diseases as well as many useful functions. The hallmark of amyloid assemblies is a conformational transition of the constituent proteins into a β - sheet rich filament. Accounting for this conformational transit...

journal_title：Scientific reports

authors： Ranganathan S,Ghosh D,Maji SK,Padinhateeri R

更新日期：2016-02-17 00:00:00

abstract：:Metabolomics studies of diseases associated with chronic alcohol consumption provide compelling evidence of several perturbed metabolic pathways. Moreover, the holistic approach of such studies gives insights into the pathophysiological risk factors associated with chronic alcohol-induced disability, morbidity and mor...

journal_title：Scientific reports

authors： Irwin C,Mienie LJ,Wevers RA,Mason S,Westerhuis JA,van Reenen M,Reinecke CJ

更新日期：2018-04-10 00:00:00

abstract：:Gene loss is a major contributor to the evolution of bacterial gene content. Gene loss may occur as a result of shifts in environment leading to changes in the intensity and/or directionality of selection applied for the maintenance of specific genes. Gene loss may also occur in a more neutral manner, when gene functi...

journal_title：Scientific reports

authors： Bolotin E,Hershberg R

更新日期：2016-10-13 00:00:00

abstract：:Autophagy is a major regulator of pancreatic beta cell homeostasis. Altered autophagic activity has been implicated in the beta cells of patients with type 2 diabetes, and in the beta cells of obese diabetic rodents. Here, we show that autophagy was induced in beta cells by either a high-fat diet or a combined high-fa...

journal_title：Scientific reports

authors： Sheng Q,Xiao X,Prasadan K,Chen C,Ming Y,Fusco J,Gangopadhyay NN,Ricks D,Gittes GK

更新日期：2017-11-27 00:00:00

abstract：:Parathyroid Hormone-Like Hormone (PTHLH) is an autocrine/paracrine ligand that is up-regulated in head and neck squamous cell carcinoma (HNSCC). However, the cellular function and regulatory mechanism in HNSCC remains obscure. We investigated the clinical significance of PTHLH in HNSCC patients, and verified the role ...

journal_title：Scientific reports

authors： Chang WM,Lin YF,Su CY,Peng HY,Chang YC,Hsiao JR,Chen CL,Chang JY,Shieh YS,Hsiao M,Shiah SG

更新日期：2017-01-25 00:00:00

abstract：:Internal solitary waves (ISWs) in the NE South China Sea (SCS) are tidally generated at the Luzon Strait. Their propagation, evolution, and dissipation processes involve numerous issues still poorly understood. Here, a novel method of seismic oceanography capable of capturing oceanic finescale structures is used to st...

journal_title：Scientific reports

authors： Tang Q,Wang C,Wang D,Pawlowicz R

更新日期：2014-06-20 00:00:00

abstract：:Outer membrane vesicles (OMVs) produced by Gram-negative bacteria have roles in cell-to-cell signaling, biofilm formation, and stress responses. Here, the effects of abiotic stressors on OMV contents and composition from biofilm cells of the plant health-promoting bacterium Pseudomonas chlororaphis O6 (PcO6) are exami...

journal_title：Scientific reports

authors： Potter M,Hanson C,Anderson AJ,Vargis E,Britt DW

更新日期：2020-12-04 00:00:00

abstract：:RNA is transcribed from DNA, and therefore, there should be no RNA transcript from the deleted DNA region. Our study attempted to analyse whether any RNA cache that maps the deleted regions is present in human cells. Using data from the 1000 genome project, we selected 41 CEPH (CEU) and 38 Yoruba (YRI) samples that in...

journal_title：Scientific reports

authors： Byeon B,Kovalchuk I

更新日期：2016-11-17 00:00:00

abstract：:Diabetic Retinopathy, the main cause of visual loss and blindness among working population, is a complication of Diabetes mellitus (DM), which has been described as a major public health challenge, so it is important to identify biomarkers to predict and to stratify patient´s possibility for developing DR. MicroRNAs (...

journal_title：Scientific reports

authors： Prado MSG,de Goes TC,de Jesus ML,Mendonça LSO,Nascimento JS,Kaneto CM

更新日期：2019-12-23 00:00:00

abstract：:In this study, a noninvasive quantitative measure was used to identify short and long term post-concussion syndrome (PCS) both from each other and from healthy control populations. We used Electrovestibulography (EVestG) for detecting neurophysiological PCS consequent to a mild traumatic brain injury (mTBI) in both sh...

journal_title：Scientific reports

authors： Suleiman A,Lithgow B,Dastgheib Z,Mansouri B,Moussavi Z

更新日期：2017-11-27 00:00:00

abstract：:A new concept for treatment of infections is induction of our own antimicrobial peptides and the presented novel class of inducer, aroylated phenylenediamines (APDs), gives up to 20 to 30-fold induction of the human antimicrobial peptide LL-37, in vitro. In addition, oral administration of an APD in a rabbit model of ...

journal_title：Scientific reports

authors： Ottosson H,Nylén F,Sarker P,Miraglia E,Bergman P,Gudmundsson GH,Raqib R,Agerberth B,Strömberg R

更新日期：2016-11-09 00:00:00

abstract：:Early detection and treatment of coronary artery disease (CAD) can reduce incidences of acute myocardial infarction. In this study, we determined the proper use of contributing risk factors and coronary artery calcium score (CACS) when screening asymptomatic patients with coronary arterial stenoses using coronary comp...

journal_title：Scientific reports

authors： Tay SY,Chang PY,Lao WT,Lin YC,Chung YH,Chan WP

更新日期：2017-12-15 00:00:00

abstract：:The mitogen-activated protein kinase (MAPK)-mediated phosphorylation cascade is a vital component of plant cellular signalling. Despite this, MAPK signalling cascade is less characterized in crop legumes. To fill this void, we present here a comprehensive phylogeny of MAPK kinases (MKKs) and MAPKs identified from 16 l...

journal_title：Scientific reports

authors： Purayannur S,Kumar K,Kaladhar VC,Verma PK

更新日期：2017-07-10 00:00:00

abstract：:Dickeya zeae is the causal agent of rice foot rot disease, which has recently become a great threat to rice planting countries and regions. The pathogen produces a family of phytotoxins named zeamines that is critical for bacterial virulence, but little is known about the signaling pathways and regulatory mechanisms t...

journal_title：Scientific reports

authors： Lv M,Chen Y,Liao L,Liang Z,Shi Z,Tang Y,Ye S,Zhou J,Zhang L

更新日期：2018-01-10 00:00:00

abstract：:Fertilisation datasets collected from field experiments (n = 21) in tea-producing areas from 2016 to 2018 were used to build a quantitative evaluation of the fertility of tropical soils (QUEFTS) model to estimate nutrient uptake of tea plants, and to investigate relationships between tea yield and nutrient accumulatio...

journal_title：Scientific reports

authors： Tang S,Liu Y,Zheng N,Li Y,Ma Q,Xiao H,Zhou X,Xu X,Jiang T,He P,Wu L

更新日期：2020-02-04 00:00:00

abstract：:With the development and application of nanotechnology, large amounts of nanoparticles will be potentially released to the environment and possibly cause many severe health problems. Although the toxicity of nanoparticles has been investigated, prevention and treatment of damages caused by nanoparticles have been rare...

journal_title：Scientific reports

authors： Qi W,Tian L,An W,Wu Q,Liu J,Jiang C,Yang J,Tang B,Zhang Y,Xie K,Wang X,Li Z,Wu W

更新日期：2017-06-06 00:00:00

abstract：:Monosodium Glutamate (MSG) is used as flavour enhancer, with potential beneficial effects due to its nutritional value. Given the decline in kidney functions during aging, we investigated the impact of MSG voluntary intake on the kidney of male mice, aged 6 or 18 months. For 2 months, they freely consumed water (contr...

journal_title：Scientific reports

authors： Celestino M,Balmaceda Valdez V,Brun P,Castagliuolo I,Mucignat-Caretta C

更新日期：2021-01-12 00:00:00

abstract：:Arctic river watersheds are important components of the global climate system and show an amplified response to climate change. Here, we characterize origins and transformations of dissolved organic matter (DOM) in five major Arctic rivers (Kolyma, Lena, Yenisei, Ob, Mackenzie) over 3 years with seasonal sampling peri...

journal_title：Scientific reports

authors： Kaiser K,Canedo-Oropeza M,McMahon R,Amon RMW

更新日期：2017-10-19 00:00:00

abstract：:The total spatial coverage of Marine Protected Areas (MPAs) within the Brazilian Economic Exclusive Zone (EEZ) has recently achieved the quantitative requirement of the Aichii Biodiversity Target 11. However, the distribution of MPAs in the Brazilian EEZ is still unbalanced regarding the proportion of protected ecosys...

journal_title：Scientific reports

authors： Endo CAK,Gherardi DFM,Pezzi LP,Lima LN

更新日期：2019-06-14 00:00:00

abstract：:The traditional approach for measuring myelin-associated water with quantitative magnetic resonance imaging (MRI) uses multi-echo T2 relaxation data to calculate the myelin water fraction (MWF). A fundamentally different approach, abbreviated "mcDESPOT", uses a more efficient steady-state acquisition to generate an eq...

journal_title：Scientific reports

authors： Dvorak AV,Ljungberg E,Vavasour IM,Lee LE,Abel S,Li DKB,Traboulsee A,MacKay AL,Kolind SH

更新日期：2021-01-14 00:00:00

abstract：:Transparent heaters have attracted increasing attention for their usefulness in vehicle windows, outdoor displays, and periscopes. We present high performance transparent heaters based on Ag nanowires with electron beam irradiation. We obtained an Ag-nanowire thin film with 48 ohm/sq of sheet resistance and 88.8% (sub...

journal_title：Scientific reports

authors： Hong CH,Oh SK,Kim TK,Cha YJ,Kwak JS,Shin JH,Ju BK,Cheong WS

更新日期：2015-12-07 00:00:00

abstract：:Medulloblastoma is a malignant pediatric tumor that arises from neural progenitors in the cerebellum. Despite a five-year survival rate of ~70%, nearly all patients incur adverse side effects from current treatment strategies that drastically impact quality of life. Roughly one-third of medulloblastoma are driven by a...

journal_title：Scientific reports

authors： Robinson MH,Maximov V,Lallani S,Farooq H,Taylor MD,Read RD,Kenney AM

更新日期：2019-09-20 00:00:00

abstract：:The next-generation logic and memory devices using magnetic skyrmions as spintronic information carriers are frequently studied, thanks to their remarkable magnetic stability, extremely compact size and very-low-cost driving forces within nanotracks. In order to realize skyrmion-based spintronic devices, understanding...

journal_title：Scientific reports

authors： Deger C,Yavuz I,Yildiz F

更新日期：2019-03-05 00:00:00

abstract：:High mortality and dependent living after hip fracture pose a significant public health concern. Retrospective study was conducted with 481 hip fracture patients (≥65 years of age) undergoing surgery from March 2009 to May 2014. The Hip-MFS was calculated by Comprehensive Geriatric Assessment (CGA). The primary outcom...

journal_title：Scientific reports

authors： Choi JY,Cho KJ,Kim SW,Yoon SJ,Kang MG,Kim KI,Lee YK,Koo KH,Kim CH

更新日期：2017-02-24 00:00:00