Modulation of brain insulin signaling in Alzheimer's disease: New insight on the protective role of green coffee bean extract.

abstract：OBJECTIVES:Alzheimer's disease (AD) is one of the most common forms of neurodegenerative diseases. Despite vast ongoing researches focusing on the area, little is known about novel treatments. In this study, we aimed to survey the effects of Capparis spinosa (C. spinosa) extract on amyloid-beta peptide (Aβ)-injected ra...

journal_title：Nutritional neuroscience

authors： Mohebali N,Shahzadeh Fazeli SA,Ghafoori H,Farahmand Z,MohammadKhani E,Vakhshiteh F,Ghamarian A,Farhangniya M,Sanati MH

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVES:The study examined the feasibility of utilizing functional magnetic resonance imaging (fMRI) with a group of adolescent boys and girls to assess modifications in cognitive function, dependent upon the nutritional state of the participants. METHODS:Twenty children aged 12-14 years completed two cognitive tri...

journal_title：Nutritional neuroscience

authors： Fulford J,Varley-Campbell JL,Williams CA

更新日期：2016-01-01 00:00:00

abstract：:A high-fat diet (HFD) during pregnancy influences the neurodevelopment of progeny, particularly in the hippocampus, a brain region involved in cognitive processes. The hippocampus has high levels of leptin receptors (Ob-R) that participate in synaptic plasticity. This study examined the effect of maternal HFD during g...

journal_title：Nutritional neuroscience

authors： Cortés-Álvarez NY,Vuelvas-Olmos CR,Pinto-González MF,Guzmán-Muñiz J,Gonzalez-Perez O,Moy-López NA

更新日期：2020-02-19 00:00:00

abstract：:The effects of perinatal undernutrition on the number of neurons and apoptotic cells of the locus coeruleus (LC) of female and male rats at postpartum days 7, 12, 20, 30 and 60 were studied. Undernutrition reduces the number of neurons in both sexes without affecting cell death, as indicated by the ratio of apoptotic ...

journal_title：Nutritional neuroscience

authors： Pinos H,Collado P,Salas M,Pérez-Torrero E

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Differences in the composition of control diets may confound outcomes in studies investigating dietary effects. OBJECTIVE:We compared the effects of two control diets commonly used in mice studies, chow (SD) and a purified low-fat diet (LFD), in relation to a chronic high-fat diet (HFD). We hypothesized tha...

journal_title：Nutritional neuroscience

authors： Almeida-Suhett CP,Scott JM,Graham A,Chen Y,Deuster PA

更新日期：2019-01-01 00:00:00

abstract：:Most previous research has focused on the effects of single neurotransmitters and neuropeptides on ingestive behavior. An important next step in the advancement of the science of ingestive behavior is to gain an understanding of how these different systems interact with one another. The present article is designed as ...

journal_title：Nutritional neuroscience

authors： Roth JD,Rowland NE

更新日期：2000-01-01 00:00:00

abstract：:Objectives: Postpartum depression (PPD) is a major depressive disorder. Vitamin D deficiency may play a role in PPD pathogenesis. This study was designed to determine the effect of vitamin D and calcium supplementation on the severity of symptoms and some related inflammatory biomarkers in women with PPD.Materials and...

journal_title：Nutritional neuroscience

authors： Amini S,Amani R,Jafarirad S,Cheraghian B,Sayyah M,Hemmati AA

更新日期：2020-01-03 00:00:00

abstract：:Objectives: A strong rise of the fructose content in the human diet occurred in the last decade, as corn syrup is widely used as a sweetener for beverages and processed food. Since young people make a widespread consumption of added sugars, we evaluated the effects of a two weeks fructose-rich diet on brain redox home...

journal_title：Nutritional neuroscience

authors： Spagnuolo MS,Bergamo P,Crescenzo R,Iannotta L,Treppiccione L,Iossa S,Cigliano L

更新日期：2020-04-01 00:00:00

abstract：:Introduction: Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized by abnormal development of cognitive, social, and communicative skills. Although ASD aetiology and pathophysiology are still unclear, various nutritional factors have been investigated as potential risk factors for AS...

journal_title：Nutritional neuroscience

authors： Infante M,Sears B,Rizzo AM,Mariani Cerati D,Caprio M,Ricordi C,Fabbri A

更新日期：2020-10-01 00:00:00

abstract：:Newborn rats maintain mother-litter bonds by using olfactory signals. At birth, units in the olfactory glomeruli (OG) are immature and vulnerable to noxious epigenetic factors like undernutrition. Because little is known about the effects of neonatal undernutrition upon the OG morphological organization, different OG ...

journal_title：Nutritional neuroscience

authors： Frias C,Torrero C,Regalado M,Salas M

更新日期：2006-02-01 00:00:00

abstract：:Background: Multiple sclerosis (MS) is associated with changes in quality of life, disability, fatigue and anthropometric measurements. The important relationship of dietary patterns with such clinical manifestations was not completely investigated. Aims: The goal of this study was to define the dietary patterns and t...

journal_title：Nutritional neuroscience

authors： Moravejolahkami AR,Paknahad Z,Chitsaz A

更新日期：2020-12-01 00:00:00

abstract：:The present study explored the effects of malnutrition and nutritional rehabilitation on the response to glucose in hypothalamic nuclei involved in metabolic homeostasis. Male Wistar rats were malnourished during gestation-lactation (MGL) or at weaning to 55 days (MPW). Two groups of rats were rehabilitated with a bal...

journal_title：Nutritional neuroscience

authors： Miñana-Solis Mdel C,Angeles-Castellanos M,Buijs RM,Escobar C

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:The rates of co-morbid depression with elderly diabetes are reportedly high. Although the intake of several nutrients has been suggested to be associated with depressive symptoms, the chronic effects of carbohydrate intake on mood remain unclear. In the current study, the association of the carbohydrate ener...

journal_title：Nutritional neuroscience

authors： Umegaki H,Iimuro S,Araki A,Sakurai T,Iguchi A,Yoshimura Y,Ohashi Y,Ito H

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine effects of probiotic yogurt and multispecies probiotic capsule supplementation on mental health and hypothalamic-pituitary-adrenal axis in petrochemical workers. METHODS:The present randomized double-blind, placebo-controlled trial was conducted on 70 petrochemical work...

journal_title：Nutritional neuroscience

authors： Mohammadi AA,Jazayeri S,Khosravi-Darani K,Solati Z,Mohammadpour N,Asemi Z,Adab Z,Djalali M,Tehrani-Doost M,Hosseini M,Eghtesadi S

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to determine the influence of dietary macronutrient composition on central NPY's orexigenic effect in chicks. METHODS:Day-of-hatch chicks were fed one of three diets (3000 kcal ME/kg) ad libitum from hatch: high carbohydrate (HC), high fat (HF; 30% ME derived from soybean oil)...

journal_title：Nutritional neuroscience

authors： McConn BR,Cline MA,Gilbert ER

更新日期：2018-07-01 00:00:00

abstract：:Endogenous neuropeptide Y (NPY) levels increase during fasting and before dark onset in rats. The feeding that follows these states elicits the release of serotonin in the lateral hypothalamus (LH), as part of the physiological mechanisms controlling satiety. With the hypothesis that exogenous NPY-induced feeding shou...

journal_title：Nutritional neuroscience

authors： Mori RC,Telles MM,Guimarães RB,Novo NF,Juliano Y,Nascimento CM,Ribeiro EB

更新日期：2004-08-01 00:00:00

abstract：:Background and objective: Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder for which no treatments exist. Fragile X syndrome (FXS) is the most common form of inherited mental retardation and the most frequent monogenic cause of ASD. Given the lack of pharmacological treatments for ASD, increasin...

journal_title：Nutritional neuroscience

authors： Schiavi S,Carbone E,Melancia F,Buzzelli V,Manduca A,Campolongo P,Pallottini V,Trezza V

更新日期：2020-09-11 00:00:00

abstract：:The effects of noise-induced arousal on chewing, subjective motivation to eat, the pleasantness of sweet food, and food intake were investigated. Twenty-four healthy normal weight male subjects received cookies differing in sucrose content (2%, 11%, 18% or 27%) before, during, and after 10 min of intermittent white no...

journal_title：Nutritional neuroscience

authors： Macht M

更新日期：1998-01-01 00:00:00

abstract：:The treatment of resistant depression has involved the use of various adjuncts in addition to the antidepressant, such as lithium or liothyronine (T3). This case report describes a woman with a history of chronic depression (dysthymic disorder), unresponsive to a number of traditional antidepressants, who was treated ...

journal_title：Nutritional neuroscience

authors： Vadnal R

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVES:It has been shown that calcitriol and all-trans retinoic acid (ATRA) have modulatory effects on the immune system. The present study investigates the synergistic effects of combination treatment of calcitriol and ATRA in experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (...

journal_title：Nutritional neuroscience

authors： Parastouei K,Mirshafiey A,Eshraghian MR,Shiri-Shahsavar MR,Solaymani-Mohammadi F,Chahardoli R,Alvandi E,Saboor-Yaraghi AA

更新日期：2018-04-01 00:00:00

abstract：:Organophosphorus compounds are widely used in agriculture. Epidemiological studies propose that pesticide exposure is a risk factor for Alzheimer's disease (AD), but the mechanisms are unclear. Here, we investigated the impact of malathion exposure on the cognitive ability and the underlying mechanisms in rats. Moreov...

journal_title：Nutritional neuroscience

authors： Mohammadzadeh L,Abnous K,Razavi BM,Hosseinzadeh H

更新日期：2020-03-01 00:00:00

abstract：:The objective of this study was to determine whether an essential fatty acid (EFA)-deficient diet (saturated fat) fed during development would alter the pattern of dendritic growth in pyramidal neurons of mouse occipital cortex. Pregnant and lactating mice were fed either a saturated fat or control diet throughout pre...

journal_title：Nutritional neuroscience

authors： Wainwright PE,Bulman-Fleming MB,Lévesque S,Mutsaers L,McCutcheon D

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVES:Stress in known to alter hormonal systems. Pharmacological doses of tryptophan, the essential amino acid precursor of serotonin, increase circulating leptin and decrease ghrelin in normal healthy adults. Because systemically injected leptin inhibits stress-induced behavioral deficits and systemically injecte...

journal_title：Nutritional neuroscience

authors： Gul S,Saleem D,Haleem MA,Haleem DJ

更新日期：2019-06-01 00:00:00

abstract：:Apelin, the endogenous peptide ligand of the APJ receptor, is expressed in brain regions implicated in food and water intake. This study reports for the first time, the effect of apelin-12, one of the most potent apelin peptides, on spontaneous (nocturnal) feeding. Randomised intracerebroventricular injection of 1, 3 ...

journal_title：Nutritional neuroscience

authors： O'Shea M,Hansen MJ,Tatemoto K,Morris MJ

更新日期：2003-06-01 00:00:00

abstract：:The kynurenine (KYN) pathway of tryptophan metabolism produces several neuroactive metabolites, including 3-hydroxykynurenine (3HK). The pathway is subject to regulation by a number of effectors including pregnancy and availability of vitamin B-6. Vitamin B-6 depleted humans and animals excrete abnormally high concent...

journal_title：Nutritional neuroscience

authors： van de Kamp JL,Smolen A

更新日期：2000-01-01 00:00:00

abstract：:We examined Dohan's hypothesis that schizophrenia is associated with the absorption of "exorphins" contained in gluten and casein. In addition, because of the work of Reichelt et al. (Reichelt, K.L., Saelid, G., Lindback, J. and Orbeck, H. (1986) Biological Psychiatry 21:1279-1290) and Rodriguez et al. (Rodriguez, Tra...

journal_title：Nutritional neuroscience

authors： Cade R,Privette M,Fregly M,Rowland N,Sun Z,Zele V,Wagemaker H,Edelstein C

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVES:To explore the association between dietary factors including fat, fruit and vegetable intake, dairy and meat consumption, and health-related quality of life (HRQOL), disability and relapse rate in a large international sample of people with multiple sclerosis (MS). METHODS:Participants with MS were recruite...

journal_title：Nutritional neuroscience

authors： Hadgkiss EJ,Jelinek GA,Weiland TJ,Pereira NG,Marck CH,van der Meer DM

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVES:To investigate the effects of Calpis sour milk whey, a Lactobacillus helveticus-fermented milk product, on learning and memory. METHODS:We evaluated improvement in scopolamine-induced memory impairment using the spontaneous alternation behaviour test, a measure of short-term memory. We also evaluated learni...

journal_title：Nutritional neuroscience

authors： Ohsawa K,Uchida N,Ohki K,Nakamura Y,Yokogoshi H

更新日期：2015-07-01 00:00:00

abstract：PURPOSE:The aim of this study was investigating the effect of omega-3 fatty acids (ω-3 FAs) on brain-derived neurotrophic factor (BDNF) gene expression, using in vivo and in vitro models, to unravel the potential mechanisms of polyunsaturated fatty acids use in obesity. MATERIALS AND METHODS:Twenty-nine Sprague-Dawley...

journal_title：Nutritional neuroscience

authors： Abdel-Maksoud SM,Hassanein SI,Gohar NA,Attia SMM,Gad MZ

更新日期：2017-10-01 00:00:00

abstract：:Phosphatidylserine (PS) is a phospholipid widely sold as a nutritional supplement. PS has been claimed to enhance neuronal membrane function and hence cognitive function, especially in the elderly. We report the results of a clinical trial of soybean-derived PS (S-PS) in aging subjects with memory complaints. Subjects...

journal_title：Nutritional neuroscience

authors： Jorissen BL,Brouns F,Van Boxtel MP,Ponds RW,Verhey FR,Jolles J,Riedel WJ

更新日期：2001-01-01 00:00:00