Feature Tracking for High Speed AFM Imaging of Biopolymers.

Abstract:

:The scanning speed of atomic force microscopes continues to advance with some current commercial microscopes achieving on the order of one frame per second and at least one reaching 10 frames per second. Despite the success of these instruments, even higher frame rates are needed with scan ranges larger than are currently achievable. Moreover, there is a significant installed base of slower instruments that would benefit from algorithmic approaches to increasing their frame rate without requiring significant hardware modifications. In this paper, we present an experimental demonstration of high speed scanning on an existing, non-high speed instrument, through the use of a feedback-based, feature-tracking algorithm that reduces imaging time by focusing on features of interest to reduce the total imaging area. Experiments on both circular and square gratings, as well as silicon steps and DNA strands show a reduction in imaging time by a factor of 3-12 over raster scanning, depending on the parameters chosen.

journal_name

Int J Mol Sci

authors

Hartman B,Andersson SB

doi

10.3390/ijms19041044

subject

Has Abstract

pub_date

2018-03-31 00:00:00

issue

4

issn

1422-0067

pii

ijms19041044

journal_volume

19

pub_type

杂志文章
  • Manifestation of Systemic Toxicity in Rats after a Short-Time Inhalation of Lead Oxide Nanoparticles.

    abstract::Outbred female rats were exposed to inhalation of lead oxide nanoparticle aerosol produced right then and there at a concentration of 1.30 ± 0.10 mg/m3 during 5 days for 4 h a day in a nose-only setup. A control group of rats were sham-exposed in parallel under similar conditions. Even this short-time exposure of a re...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21030690

    authors: Sutunkova MP,Solovyeva SN,Chernyshov IN,Klinova SV,Gurvich VB,Shur VY,Shishkina EV,Zubarev IV,Privalova LI,Katsnelson BA

    更新日期:2020-01-21 00:00:00

  • Exploring miR-9 Involvement in Ciona intestinalis Neural Development Using Peptide Nucleic Acids.

    abstract::The microRNAs are small RNAs that regulate gene expression at the post-transcriptional level and can be involved in the onset of neurodegenerative diseases and cancer. They are emerging as possible targets for antisense-based therapy, even though the in vivo stability of miRNA analogues is still questioned. We tested ...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21062001

    authors: Mercurio S,Cauteruccio S,Manenti R,Candiani S,Scarì G,Licandro E,Pennati R

    更新日期:2020-03-15 00:00:00

  • Hepatic microRNA Expression by PGC-1α and PGC-1β in the Mouse.

    abstract::The fine-tuning of liver metabolism is essential to maintain the whole-body homeostasis and to prevent the onset of diseases. The peroxisome proliferator-activated receptor-γ coactivators (PGC-1s) are transcriptional key players of liver metabolism, able to regulate mitochondrial function, gluconeogenesis and lipid me...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms20225735

    authors: Piccinin E,Arconzo M,Graziano G,Vacca M,Peres C,Bellafante E,Villani G,Moschetta A

    更新日期:2019-11-15 00:00:00

  • Angiotensin II, Hypercholesterolemia, and Vascular Smooth Muscle Cells: A Perfect Trio for Vascular Pathology.

    abstract::Cardiovascular disease is the leading cause of morbidity and mortality in the Western and developing world, and the incidence of cardiovascular disease is increasing with the longer lifespan afforded by our modern lifestyle. Vascular diseases including coronary heart disease, high blood pressure, and stroke comprise t...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms21124525

    authors: St Paul A,Corbett CB,Okune R,Autieri MV

    更新日期:2020-06-25 00:00:00

  • Immune-Specific Expression and Estrogenic Regulation of the Four Estrogen Receptor Isoforms in Female Rainbow Trout (Oncorhynchus mykiss).

    abstract::Genomic actions of estrogens in vertebrates are exerted via two intracellular estrogen receptor (ER) subtypes, ERα and ERβ, which show cell- and tissue-specific expression profiles. Mammalian immune cells express ERs and are responsive to estrogens. More recently, evidence became available that ERs are also present in...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms19040932

    authors: Casanova-Nakayama A,Wernicke von Siebenthal E,Kropf C,Oldenberg E,Segner H

    更新日期:2018-03-21 00:00:00

  • Effect of Sonication on the Properties of Flaxseed Gum Films Incorporated with Carvacrol.

    abstract::Carvacrol is a natural compound known to be a highly effective antibacterial; however, it is a hydrophobic molecule, which is a limitation to its use within food packaging. Flaxseed gum (FG) films containing different contents of carvacrol (C) were produced by a film-casting method with sonication. The effects of sonic...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21051637

    authors: Fang S,Qiu W,Mei J,Xie J

    更新日期:2020-02-28 00:00:00

  • High-Dimensional descriptor selection and computational QSAR modeling for antitumor activity of ARC-111 analogues Based on Support Vector Regression (SVR).

    abstract::To design ARC-111 analogues with improved efficiency, we constructed the QSAR of 22 ARC-111 analogues with RPMI8402 tumor cells. First, the optimized support vector regression (SVR) model based on the literature descriptors and the worst descriptor elimination multi-roundly (WDEM) method had similar generalization as ...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms13011161

    authors: Zhou W,Dai Z,Chen Y,Wang H,Yuan Z

    更新日期:2012-01-01 00:00:00

  • The Role of Chemokines in the Development of Gastric Cancer - Diagnostic and Therapeutic Implications.

    abstract::Gastric cancer (GC) is the fifth most common cancer worldwide and the second leading cause of cancer-related death. GC is usually diagnosed at an advanced stage due to late presentation of symptoms. Therefore, there is a need for establishing more sensitive and specific markers useful in early detection of the disease...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms21228456

    authors: Pawluczuk E,Łukaszewicz-Zając M,Mroczko B

    更新日期:2020-11-10 00:00:00

  • Antibacterial activity of the alkaloid-enriched extract from Prosopis juliflora pods and its influence on in vitro ruminal digestion.

    abstract::The purpose of this study was to assess the in vitro antimicrobial activity of alkaloid-enriched extracts from Prosopis juliflora (Fabaceae) pods in order to evaluate them as feed additives for ruminants. As only the basic chloroformic extract (BCE), whose main constituents were juliprosopine (juliflorine), prosoflori...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms14048496

    authors: Dos Santos ET,Pereira ML,da Silva CF,Souza-Neta LC,Geris R,Martins D,Santana AE,Barbosa LC,Silva HG,Freitas GC,Figueiredo MP,de Oliveira FF,Batista R

    更新日期:2013-04-17 00:00:00

  • The Role of miR-375-3p and miR-200b-3p in Gastrointestinal Stromal Tumors.

    abstract::Deregulated microRNA (miRNA) expression profiles and their contribution to carcinogenesis have been observed in virtually all types of human cancer. However, their role in the pathogenesis of rare mesenchymal gastrointestinal stromal tumors (GISTs) is not well defined, yet. In this study, we aimed to investigate the r...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21145151

    authors: Gyvyte U,Lukosevicius R,Inciuraite R,Streleckiene G,Gudoityte G,Bekampyte J,Valentini S,Salteniene V,Ruzgys P,Satkauskas S,Zviniene K,Kupcinskas J,Skieceviciene J

    更新日期:2020-07-21 00:00:00

  • Receptor Tyrosine Kinases in Development: Insights from Drosophila.

    abstract::Cell-to-cell communication mediates a plethora of cellular decisions and behaviors that are crucial for the correct and robust development of multicellular organisms. Many of these signals are encoded in secreted hormones or growth factors that bind to and activate cell surface receptors, to transmit the cue intracell...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms21010188

    authors: Mele S,Johnson TK

    更新日期:2019-12-26 00:00:00

  • Synergistic Effect of Beauveria bassiana and Trichoderma asperellum to Induce Maize (Zea mays L.) Defense against the Asian Corn Borer, Ostrinia furnacalis (Lepidoptera, Crambidae) and Larval Immune Response.

    abstract::Ostrinia furnacalis, is the major pest of maize causing significant yield losses. So far, many approaches have been used to increase the virulence of entomopathogenic fungal isolates. The current study is an attempt to estimate synergistic effect of Beauveria bassiana and Trichoderma asperellum in order to explore lar...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21218215

    authors: Batool R,Umer MJ,Wang Y,He K,Zhang T,Bai S,Zhi Y,Chen J,Wang Z

    更新日期:2020-11-03 00:00:00

  • Hepatotoxicity by Drugs: The Most Common Implicated Agents.

    abstract::Idiosyncratic drug-induced liver injury (DILI) is an underreported and underestimated adverse drug reaction. Information on the documented hepatotoxicity of drugs has recently been made available by a website that can be accessed in the public domain: LiverTox (http://livertox.nlm.nih.gov). According to critical analy...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms17020224

    authors: Björnsson ES

    更新日期:2016-02-06 00:00:00

  • CSPG4 as Target for CAR-T-Cell Therapy of Various Tumor Entities-Merits and Challenges.

    abstract::Targeting cancer cells using chimeric-antigen-receptor (CAR-)T cells has propelled adoptive T-cell therapy (ATT) to the next level. A plentitude of durable complete responses using CD19-specific CAR-T cells in patients suffering from various lymphoid malignancies resulted in the approval by the food and drug administr...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms20235942

    authors: Harrer DC,Dörrie J,Schaft N

    更新日期:2019-11-26 00:00:00

  • An algorithm for emulsion stability simulations: account of flocculation, coalescence, surfactant adsorption and the process of Ostwald ripening.

    abstract::The first algorithm for Emulsion Stability Simulations (ESS) was presented at the V Conferencia Iberoamericana sobre Equilibrio de Fases y Diseño de Procesos [Luis, J.; García-Sucre, M.; Urbina-Villalba, G. Brownian Dynamics Simulation of Emulsion Stability In: Equifase 99. Libro de Actas, 1(st) Ed., Tojo J., Arce, A....

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms10030761

    authors: Urbina-Villalba G

    更新日期:2009-03-01 00:00:00

  • psbE-psbL and ndhA Intron, the Promising Plastid DNA Barcode of Fagopyrum.

    abstract::Buckwheat is an important functional food material with high nutritional value. However, it is still a difficult task for the taxonomy studies of wild buckwheat that are only based on morphology. In order to demonstrate the most efficient DNA barcode in the phylogenetic research of buckwheat, promote the investigation...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms20143455

    authors: Huang Y,Li Z,Wang C,Zou C,Wen W,Shao J,Zhu X

    更新日期:2019-07-14 00:00:00

  • The voltage-dependent anion channel 1 (AtVDAC1) negatively regulates plant cold responses during germination and seedling development in Arabidopsis and interacts with calcium sensor CBL1.

    abstract::The voltage-dependent anion channel (VDAC), a highly conserved major mitochondrial outer membrane protein, plays crucial roles in energy metabolism and metabolite transport. However, knowledge about the roles of the VDAC family in plants is limited. In this study, we investigated the expression pattern of VDAC1 in Ara...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms14010701

    authors: Li ZY,Xu ZS,He GY,Yang GX,Chen M,Li LC,Ma Y

    更新日期:2013-01-04 00:00:00

  • Pulicaria glutinosa extract: a toolbox to synthesize highly reduced graphene oxide-silver nanocomposites.

    abstract::A green, one-step approach for the preparation of graphene/Ag nanocomposites (PE-HRG-Ag) via simultaneous reduction of both graphene oxide (GRO) and silver ions using Pulicaria glutinosa plant extract (PE) as reducing agent is reported. The plant extract functionalizes the surfaces of highly reduced graphene oxide (HR...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms16011131

    authors: Al-Marri AH,Khan M,Khan M,Adil SF,Al-Warthan A,Alkhathlan HZ,Tremel W,Labis JP,Siddiqui MR,Tahir MN

    更新日期:2015-01-05 00:00:00

  • ER Stress-Mediated Signaling: Action Potential and Ca(2+) as Key Players.

    abstract::The proper functioning of the endoplasmic reticulum (ER) is crucial for multiple cellular activities and survival. Disturbances in the normal ER functions lead to the accumulation and aggregation of unfolded proteins, which initiates an adaptive response, the unfolded protein response (UPR), in order to regain normal ...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms17091558

    authors: Bahar E,Kim H,Yoon H

    更新日期:2016-09-15 00:00:00

  • TmSpz4 Plays an Important Role in Regulating the Production of Antimicrobial Peptides in Response to Escherichia coli and Candida albicans Infections.

    abstract::Spätzle family proteins activate the Toll pathway and induce antimicrobial peptide (AMP) production against microbial infections. However, the functional importance of Tmspätzle4 (TmSpz4) in the immune response of Tenebrio molitor has not been reported. Therefore, here, we have identified and functionally characterize...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21051878

    authors: Edosa TT,Jo YH,Keshavarz M,Bae YM,Kim DH,Lee YS,Han YS

    更新日期:2020-03-09 00:00:00

  • The Zinc Sensing Receptor, ZnR/GPR39, in Health and Disease.

    abstract::A distinct G-protein coupled receptor that senses changes in extracellular Zn2+, ZnR/GPR39, was found in cells from tissues in which Zn2+ plays a physiological role. Most prominently, ZnR/GPR39 activity was described in prostate cancer, skin keratinocytes, and colon epithelial cells, where zinc is essential for cell g...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms19020439

    authors: Hershfinkel M

    更新日期:2018-02-01 00:00:00

  • Obatoclax, a Pan-BCL-2 Inhibitor, Downregulates Survivin to Induce Apoptosis in Human Colorectal Carcinoma Cells Via Suppressing WNT/β-catenin Signaling.

    abstract::Colorectal cancer (CRC) is a highly prevailing cancer and the fourth leading cause of cancer mortality worldwide. Aberrant expression of antiapoptotic BCL-2 family proteins is closely linked to neoplastic progression and chemoresistance. Obatoclax is a clinically developed drug, which binds antiapoptotic BCL-2, BCL-xL...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21051773

    authors: Or CR,Huang CW,Chang CC,Lai YC,Chen YJ,Chang CC

    更新日期:2020-03-05 00:00:00

  • The Role of the RNA-Binding Protein Family MEX-3 in Tumorigenesis.

    abstract::The muscle excess 3 (MEX-3) protein was first identified in Caenorhabditis elegans (C. elegans), and its respective homologues were also observed in vertebrates, including humans. It is a RNA-binding protein (RBP) with an additional ubiquitin E3 ligase function, which further acts as a post-transcriptional repressor t...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms21155209

    authors: Jasinski-Bergner S,Steven A,Seliger B

    更新日期:2020-07-23 00:00:00

  • Canonical, Non-Canonical and Atypical Pathways of Nuclear Factor кb Activation in Preeclampsia.

    abstract::Although higher nuclear factor κB (NFκB) expression and activity is observed in preeclamptic placentas, its mechanism of activation is unknown. This is the first study to investigate whether the canonical, non-canonical, or atypical NFκB activation pathways may be responsible for the higher activation of NFκB observed...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21155574

    authors: Sakowicz A,Bralewska M,Pietrucha T,Habrowska-Górczyńska DE,Piastowska-Ciesielska AW,Gach A,Rybak-Krzyszkowska M,Witas PJ,Huras H,Grzesiak M,Biesiada L

    更新日期:2020-08-04 00:00:00

  • Modeling human liver biology using stem cell-derived hepatocytes.

    abstract::Stem cell-derived hepatocytes represent promising models to study human liver biology and disease. This concise review discusses the recent progresses in the field, with a focus on human liver disease, drug metabolism and virus infection. ...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms141122011

    authors: Sun P,Zhou X,Farnworth SL,Patel AH,Hay DC

    更新日期:2013-11-06 00:00:00

  • Neuroprotection by Neurotropin through Crosstalk of Neurotrophic and Innate Immune Receptors in PC12 Cells.

    abstract::Infected or damaged tissues release multiple "alert" molecules such as alarmins and damage-associated molecular patterns (DAMPs) that are recognized by innate immune receptors, and induce tissue inflammation, regeneration, and repair. Recently, an extract from inflamed rabbit skin inoculated with vaccinia virus (Neuro...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21186456

    authors: Fukuda Y,Nakajima K,Mutoh T

    更新日期:2020-09-04 00:00:00

  • Synthesis and Characterization of Tissue Plasminogen Activator-Functionalized Superparamagnetic Iron Oxide Nanoparticles for Targeted Fibrin Clot Dissolution.

    abstract::Superparamagnetic iron oxide nanoparticles (SPIONs) have attracted great attention in many biomedical fields and are used in preclinical/experimental drug delivery, hyperthermia and medical imaging. In this study, biocompatible magnetite drug carriers, stabilized by a dextran shell, were developed to carry tissue plas...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms18091837

    authors: Heid S,Unterweger H,Tietze R,Friedrich RP,Weigel B,Cicha I,Eberbeck D,Boccaccini AR,Alexiou C,Lyer S

    更新日期:2017-08-24 00:00:00

  • Serum Matrix Metalloproteinases and Left Atrial Remodeling-The Hoorn Study.

    abstract::Extracellular matrix protein turnover may play an important role in left atrial (LA) remodelling. The aim is to investigate the associations between matrix metalloproteinase (MMPs), tissue inhibitor of metalloproteinase (TIMP-1) and LA volume index (LAVI) and if these associations are independent of TIMP-1 levels. Par...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21144944

    authors: Linssen PBC,Brunner-La Rocca HP,Schalkwijk CG,Beulens JWJ,Elders PJM,van der Heijden AA,Slieker RC,Stehouwer CDA,Henry RMA

    更新日期:2020-07-13 00:00:00

  • Rack1 Mediates the Interaction of P-Glycoprotein with Anxa2 and Regulates Migration and Invasion of Multidrug-Resistant Breast Cancer Cells.

    abstract::The emergence of multidrug resistance is always associated with more rapid tumor recurrence and metastasis. P-glycoprotein (P-gp), which is a well-known multidrug-efflux transporter, confers enhanced invasion ability in drug-resistant cells. Previous studies have shown that P-gp probably exerts its tumor-promoting fun...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms17101718

    authors: Yang Y,Wu N,Wang Z,Zhang F,Tian R,Ji W,Ren X,Niu R

    更新日期:2016-10-13 00:00:00

  • Fusion of Mitochondria to 3-D Networks, Autophagy and Increased Organelle Contacts are Important Subcellular Hallmarks during Cold Stress in Plants.

    abstract::Low temperature stress has a severe impact on the distribution, physiology, and survival of plants in their natural habitats. While numerous studies have focused on the physiological and molecular adjustments to low temperatures, this study provides evidence that cold induced physiological responses coincide with dist...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21228753

    authors: Steiner P,Buchner O,Andosch A,Wanner G,Neuner G,Lütz-Meindl U

    更新日期:2020-11-19 00:00:00