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Antibacterial activity of the alkaloid-enriched extract from Prosopis juliflora pods and its influence on in vitro ruminal digestion.

Abstract：

:The purpose of this study was to assess the in vitro antimicrobial activity of alkaloid-enriched extracts from Prosopis juliflora (Fabaceae) pods in order to evaluate them as feed additives for ruminants. As only the basic chloroformic extract (BCE), whose main constituents were juliprosopine (juliflorine), prosoflorine and juliprosine, showed Gram-positive antibacterial activity against Micrococcus luteus (MIC = 25 μg/mL), Staphylococcus aureus (MIC = 50 μg/mL) and Streptococcus mutans (MIC = 50 μg/mL), its influence on ruminal digestion was evaluated using a semi-automated in vitro gas production technique, with monensin as the positive control. Results showed that BCE has decreased gas production as efficiently as monensin after 36 h of fermentation, revealing its positive influence on gas production during ruminal digestion. Since P. juliflora is a very affordable plant, this study points out this alkaloid enriched extract from the pods of Prosopis juliflora as a potential feed additive to decrease gas production during ruminal digestion.

journal_name

Int J Mol Sci

journal_title

International journal of molecular sciences

authors

Dos Santos ET,Pereira ML,da Silva CF,Souza-Neta LC,Geris R,Martins D,Santana AE,Barbosa LC,Silva HG,Freitas GC,Figueiredo MP,de Oliveira FF,Batista R

doi

10.3390/ijms14048496

subject

Has Abstract

pub_date

2013-04-17 00:00:00

pages

8496-516

issue

4

issn

1422-0067

pii

ijms14048496

journal_volume

14

pub_type

杂志文章

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