当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES期刊下所有文献 > The voltage-dependent anion channel 1 (AtVDAC1) negatively regulates plant cold responses during germination and seedling development in Arabidopsis and interacts with calcium sensor CBL1.

The voltage-dependent anion channel 1 (AtVDAC1) negatively regulates plant cold responses during germination and seedling development in Arabidopsis and interacts with calcium sensor CBL1.

Abstract：

:The voltage-dependent anion channel (VDAC), a highly conserved major mitochondrial outer membrane protein, plays crucial roles in energy metabolism and metabolite transport. However, knowledge about the roles of the VDAC family in plants is limited. In this study, we investigated the expression pattern of VDAC1 in Arabidopsis and found that cold stress promoted the accumulation of VDAC1 transcripts in imbibed seeds and mature plants. Overexpression of VDAC1 reduced tolerance to cold stress in Arabidopsis. Phenotype analysis of VDAC1 T-DNA insertion mutant plants indicated that a vdac1 mutant line had faster germination kinetics under cold treatment and showed enhanced tolerance to freezing. The yeast two-hybrid system revealed that VDAC1 interacts with CBL1, a calcium sensor in plants. Like the vdac1, a cbl1 mutant also exhibited a higher seed germination rate. We conclude that both VDAC1 and CBL1 regulate cold stress responses during seed germination and plant development.

journal_name

Int J Mol Sci

journal_title

International journal of molecular sciences

authors

Li ZY,Xu ZS,He GY,Yang GX,Chen M,Li LC,Ma Y

doi

10.3390/ijms14010701

subject

Has Abstract

pub_date

2013-01-04 00:00:00

pages

701-13

issue

1

issn

1422-0067

pii

ijms14010701

journal_volume

14

pub_type

杂志文章

相关文献

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES文献大全
  • Multiple Layers of CDK5R1 Regulation in Alzheimer's Disease Implicate Long Non-Coding RNAs.

    abstract：:Cyclin-dependent kinase 5 regulatory subunit 1 (CDK5R1) gene encodes for p35, the main activator of Cyclin-dependent kinase 5 (CDK5). The active p35/CDK5 complex is involved in numerous aspects of brain development and function, and its deregulation is closely associated to Alzheimer's disease (AD) onset and progressi...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms19072022

    authors： Spreafico M,Grillo B,Rusconi F,Battaglioli E,Venturin M

    更新日期：2018-07-11 00:00:00

  • Quercetin improves postischemic recovery of heart function in doxorubicin-treated rats and prevents doxorubicin-induced matrix metalloproteinase-2 activation and apoptosis induction.

    abstract：:Quercetin (QCT) is flavonoid that possesses various biological functions including anti-oxidative and radical-scavenging activities. Moreover, QCT exerts some preventive actions in treatment of cardiovascular diseases. The aim of present study was to explore effects of prolonged administration of QCT on changes induce...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms16048168

    authors： Barteková M,Šimončíková P,Fogarassyová M,Ivanová M,Okruhlicová Ľ,Tribulová N,Dovinová I,Barančík M

    更新日期：2015-04-13 00:00:00

  • Antidiabetic Effects of Bisamide Derivative of Dicarboxylic Acid in Metabolic Disorders.

    abstract：:In clinical practice, the metabolic syndrome can lead to multiple complications, including diabetes. It remains unclear which component of the metabolic syndrome (obesity, inflammation, hyperglycemia, or insulin resistance) has the strongest inhibitory effect on stem cells involved in beta cell regeneration. This make...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms21030991

    authors： Vladimirovna Pakhomova A,Nebolsin VE,Victorovna Pershina O,Andreevich Krupin V,Alexandrovna Sandrikina L,Sergeevich Pan E,Nicolaevna Ermakova N,Evgenevna Vaizova O,Widera D,Grimm WD,Yur'evich Kravtsov V,Alexandrovich Afanasiev S,

    更新日期：2020-02-03 00:00:00

  • Resveratrol induces the expression of interleukin-10 and brain-derived neurotrophic factor in BV2 microglia under hypoxia.

    abstract：:Microglia are the resident macrophages of the central nervous system (CNS) and play an important role in neuronal recovery by scavenging damaged neurons. However, overactivation of microglia leads to neuronal death that is associated with CNS disorders. Therefore, regulation of microglial activation has been suggested...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms150915512

    authors： Song J,Cheon SY,Jung W,Lee WT,Lee JE

    更新日期：2014-09-02 00:00:00

  • Experimental construction of BMP2 and VEGF gene modified tissue engineering bone in vitro.

    abstract：:The purpose of this study was to investigate the feasibility and advantages of constructing a novel tissue engineering bone, using β-tricalcium phosphate (β-TCP) and rat bone marrow mesenchymal stem cells (MSCs), modified with human bone morphogenetic protein 2 gene (hBMP2) and human vascular endothelial growth factor...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms12031744

    authors： Jiang J,Fan CY,Zeng BF

    更新日期：2011-01-01 00:00:00

  • 8q24.21 Locus: A Paradigm to Link Non-Coding RNAs, Genome Polymorphisms and Cancer.

    abstract：:The majority of the human genome is comprised of non-protein-coding genes, but the relevance of non-coding RNAs in complex diseases has yet to be fully elucidated. One class of non-coding RNAs is long non-coding RNAs or lncRNAs, many of which have been identified to play a range of roles in transcription and translati...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章,评审

    doi：10.3390/ijms22031094

    authors： Wilson C,Kanhere A

    更新日期：2021-01-22 00:00:00

  • Downregulation of FOXP1 Inhibits Cell Proliferation in Hepatocellular Carcinoma by Inducing G1/S Phase Cell Cycle Arrest.

    abstract：:Forkhead box P1 (FOXP1) belongs to a family of winged-helix transcription factors that are involved in the processes of cellular proliferation, differentiation, metabolism, and longevity. FOXP1 can affect cell proliferation and migratory ability in hepatocellular carcinoma (HCC) in vitro. However, little is known abou...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms17091501

    authors： Wang X,Sun J,Cui M,Zhao F,Ge C,Chen T,Yao M,Li J

    更新日期：2016-09-08 00:00:00

  • Late-Onset N-Acetylglutamate Synthase Deficiency: Report of a Paradigmatic Adult Case Presenting with Headaches and Review of the Literature.

    abstract：:N-acetylglutamate synthase deficiency (NAGSD) is an extremely rare urea cycle disorder (UCD) with few adult cases so far described. Diagnosis of late-onset presentations is difficult and delayed treatment may increase the risk of severe hyperammonemia. We describe a 52-year-old woman with recurrent headaches who exper...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章,评审

    doi：10.3390/ijms19020345

    authors： Cavicchi C,Chilleri C,Fioravanti A,Ferri L,Ripandelli F,Costa C,Calabresi P,Prontera P,Pochiero F,Pasquini E,Funghini S,la Marca G,Donati MA,Morrone A

    更新日期：2018-01-24 00:00:00

  • Tumour-Derived Extracellular Vesicles (EVs): A Dangerous "Message in A Bottle" for Bone.

    abstract：:Several studies have shown the importance of Extracellular Vesicles (EVs) in the intercellular communication between tumour and resident cells. Through EVs, tumour cells can trigger cell-signalling molecules and shuttle exogenous information to target cells, thus promoting spread of the disease. In fact, many processe...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章,评审

    doi：10.3390/ijms20194805

    authors： Cappariello A,Rucci N

    更新日期：2019-09-27 00:00:00

  • Deregulation of Frizzled Receptors in Hepatocellular Carcinoma.

    abstract：:G protein-coupled receptors (GPCRs) have a substantial role in tumorigenesis and are described as a "cancer driver". Aberrant expression or activation of GPCRs leads to the deregulation of downstream signaling pathways, thereby promoting cancer progression. In hepatocellular carcinoma (HCC), the Wnt signaling pathway ...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章,评审

    doi：10.3390/ijms19010313

    authors： Chan KK,Lo RC

    更新日期：2018-01-21 00:00:00

  • Seed Germination in Oil Palm (Elaeis guineensis Jacq.): A Review of Metabolic Pathways and Control Mechanisms.

    abstract：:Oil palm is an oil-producing crop of major importance at the global scale. Oil palm mesocarp lipids are used for myriads industrial applications, and market demand has been growing for decades. In addition, oil palm seeds are oleaginous, and the oil extracted therefrom can be used for several purposes, from food to co...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章,评审

    doi：10.3390/ijms21124227

    authors： Cui J,Lamade E,Tcherkez G

    更新日期：2020-06-13 00:00:00

  • Isolation of a pluripotent neural stem cell from the embryonic bovine brain.

    abstract：:We recently isolated stem cells derived from the brain of a bovine fetus, utilizing a particular mechanical separation method. After improving our experimental conditions, we obtained neural stem cells using an optimized culture medium system. The cells were expanded, established in continuous cell culture and used fo...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms16035990

    authors： Gao Y,Li X,Zheng D,Guan W,Ma Y

    更新日期：2015-03-13 00:00:00

  • Identification and Characterization of Approved Drugs and Drug-Like Compounds as Covalent Escherichia coli ClpP Inhibitors.

    abstract：:The serine protease Caseinolytic protease subunit P (ClpP) plays an important role for protein homeostasis in bacteria and contributes to various developmental processes, as well as virulence. Therefore, ClpP is considered as a potential drug target in Gram-positive and Gram-negative bacteria. In this study, we utiliz...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms20112686

    authors： Sassetti E,Durante Cruz C,Tammela P,Winterhalter M,Augustyns K,Gribbon P,Windshügel B

    更新日期：2019-05-31 00:00:00

  • Remodeler Catalyzed Nucleosome Repositioning: Influence of Structure and Stability.

    abstract：:The packaging of the eukaryotic genome into chromatin regulates the storage of genetic information, including the access of the cell's DNA metabolism machinery. Indeed, since the processes of DNA replication, translation, and repair require access to the underlying DNA, several mechanisms, both active and passive, hav...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章,评审

    doi：10.3390/ijms22010076

    authors： Morgan A,LeGresley S,Fischer C

    更新日期：2020-12-23 00:00:00

  • Anti-c-fms Antibody Prevents Osteoclast Formation and Bone Resorption in Co-Culture of Osteoblasts and Osteoclast Precursors In Vitro and in Ovariectomized Mice.

    abstract：:Osteoporosis morphology is characterized by bone resorption and decreases in micro-architecture parameters. Anti-osteoporosis therapy targets osteoclasts because bone resorption is a unique function of osteoclasts. Anti-c-fms antibodies against the receptor for macrophage colony-stimulating factor (M-CSF) inhibit oste...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms21176120

    authors： Nara Y,Kitaura H,Ogawa S,Shen WR,Qi J,Ohori F,Noguchi T,Marahleh A,Pramusita A,Kinjo R,Mizoguchi I

    更新日期：2020-08-25 00:00:00

  • Possible Immune Regulation of Natural Killer T Cells in a Murine Model of Metal Ion-Induced Allergic Contact Dermatitis.

    abstract：:Metal often causes delayed-type hypersensitivity reactions, which are possibly mediated by accumulating T cells in the inflamed skin, called irritant or allergic contact dermatitis. However, accumulating T cells during development of a metal allergy are poorly characterized because a suitable animal model is unavailab...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章,评审

    doi：10.3390/ijms17010087

    authors： Kumagai K,Horikawa T,Shigematsu H,Matsubara R,Kitaura K,Eguchi T,Kobayashi H,Nakasone Y,Sato K,Yamada H,Suzuki S,Hamada Y,Suzuki R

    更新日期：2016-01-12 00:00:00

  • LGM2605 Reduces Space Radiation-Induced NLRP3 Inflammasome Activation and Damage in In Vitro Lung Vascular Networks.

    abstract：:Updated measurements of charged particle fluxes during the transit from Earth to Mars as well as on site measurements by Curiosity of Martian surface radiation fluxes identified potential health hazards associated with radiation exposure for human space missions. Designing mitigation strategies of radiation risks to a...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms20010176

    authors： Chatterjee S,Pietrofesa RA,Park K,Tao JQ,Carabe-Fernandez A,Berman AT,Koumenis C,Sielecki T,Christofidou-Solomidou M

    更新日期：2019-01-05 00:00:00

  • Clinical Considerations for a Family with Dilated Cardiomyopathy, Sudden Cardiac Death, and a Novel TTN Frameshift Mutation.

    abstract：:Dilated cardiomyopathy (DCM) is the leading indication for heart transplantation. TTN gene truncating mutations account for about 25% of familial DCM cases and for 18% of sporadic DCM cases. The clinical relevance of specific variants in TTN has been difficult to determine because of the sheer size of the protein for ...

    journal_title：International journal of molecular sciences

    pub_type：

    doi：10.3390/ijms22020670

    authors： Micaglio E,Monasky MM,Bernardini A,Mecarocci V,Borrelli V,Ciconte G,Locati ET,Piccoli M,Ghiroldi A,Anastasia L,Pappone C

    更新日期：2021-01-12 00:00:00

  • New Hope for Pancreatic Ductal Adenocarcinoma Treatment Targeting Endoplasmic Reticulum Stress Response: A Systematic Review.

    abstract：:Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal types of tumours, and its incidence is rising worldwide. Although survival can be improved by surgical resection when these tumours are detected at an early stage, this cancer is usually asymptomatic, and disease only becomes apparent after metastasis. ...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章,评审

    doi：10.3390/ijms19092468

    authors： Garcia-Carbonero N,Li W,Cabeza-Morales M,Martinez-Useros J,Garcia-Foncillas J

    更新日期：2018-08-21 00:00:00

  • Interleukin-10 Protection against Lipopolysaccharide-Induced Neuro-Inflammation and Neurotoxicity in Ventral Mesencephalic Cultures.

    abstract：:Interleukin (IL)-10, an anti-inflammatory cytokine, is expressed in the brain and can inhibit microglial activation. Herein, we utilized lipopolysaccharide (LPS)-induced inflammatory Parkinson's disease (PD) cell model to determine whether microglia and astrocytes are necessary targets for IL-10 neuroprotection. Prima...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms17010025

    authors： Zhu Y,Chen X,Liu Z,Peng YP,Qiu YH

    更新日期：2015-12-28 00:00:00

  • PPARβ/δ: A Key Therapeutic Target in Metabolic Disorders.

    abstract：:Research in recent years on peroxisome proliferator-activated receptor (PPAR)β/δ indicates that it plays a key role in the maintenance of energy homeostasis, both at the cellular level and within the organism as a whole. PPARβ/δ activation might help prevent the development of metabolic disorders, including obesity, d...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章,评审

    doi：10.3390/ijms19030913

    authors： Palomer X,Barroso E,Pizarro-Delgado J,Peña L,Botteri G,Zarei M,Aguilar D,Montori-Grau M,Vázquez-Carrera M

    更新日期：2018-03-20 00:00:00

  • Expression and Localization of BDNF/TrkB System in the Zebrafish Inner Ear.

    abstract：:Brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family, is involved in multiple and fundamental functions of the central and peripheral nervous systems including sensory organs. Despite recent advances in knowledge on the functional significance of BDNF and TrkB in the regulation of the acoustic...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms21165787

    authors： Germanà A,Guerrera MC,Laurà R,Levanti M,Aragona M,Mhalhel K,Germanà G,Montalbano G,Abbate F

    更新日期：2020-08-12 00:00:00

  • Role of Inflammation in Diabetic Retinopathy.

    abstract：:Diabetic retinopathy is a common complication of diabetes and remains the leading cause of blindness among the working-age population. For decades, diabetic retinopathy was considered only a microvascular complication, but the retinal microvasculature is intimately associated with and governed by neurons and glia, whi...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章,评审

    doi：10.3390/ijms19040942

    authors： Rübsam A,Parikh S,Fort PE

    更新日期：2018-03-22 00:00:00

  • Needle in a Haystack: The Naïve Repertoire as a Source of T Cell Receptors for Adoptive Therapy with Engineered T Cells.

    abstract：:T cell engineering with antigen-specific T cell receptors (TCRs) has allowed the generation of increasingly specific, reliable, and versatile T cell products with near-physiological features. However, a broad applicability of TCR-based therapies in cancer is still limited by the restricted number of TCRs, often also o...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章,评审

    doi：10.3390/ijms21218324

    authors： D'Ippolito E,Wagner KI,Busch DH

    更新日期：2020-11-06 00:00:00

  • Impact of Trail Running Races on Blood Viscosity and Its Determinants: Effects of Distance.

    abstract：:Blood rheology is a key determinant of tissue perfusion at rest and during exercise. The present study investigated the effects of race distance on hematological, blood rheological, and red blood cell (RBC) senescence parameters. Eleven runners participated in the Martigny-Combes à Chamonix 40 km race (MCC, elevation ...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms21228531

    authors： Robert M,Stauffer E,Nader E,Skinner S,Boisson C,Cibiel A,Feasson L,Renoux C,Robach P,Joly P,Millet GY,Connes P

    更新日期：2020-11-12 00:00:00

  • N-Caffeoyltryptamine, a Potent Anti-Inflammatory Phenolic Amide, Suppressed MCP-1 Expression in LPS-stimulated THP-1 Cells and Rats Fed a High-Fat Diet.

    abstract：:Monocyte chemoattractant protein-1 (MCP-1) is a well-known chemokine critically involved in the pathophysiological progression of several inflammatory diseases including arthrosclerosis. N-caffeoyltryptamine is a phenolic amide with strong anti-inflammatory effects. Therefore, in this paper, the potential effect of N-...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms18061148

    authors： Park JB

    更新日期：2017-05-27 00:00:00

  • Leucine-Rich Repeat Kinase 2 Controls Inflammatory Cytokines Production through NF-κB Phosphorylation and Antigen Presentation in Bone Marrow-Derived Dendritic Cells.

    abstract：:Leucine-rich repeat kinase 2 (LRRK2) is the causal molecule of familial Parkinson's disease. Although the characteristics of LRRK2 have gradually been revealed, its true physiological functions remain unknown. LRRK2 is highly expressed in immune cells such as B2 cells and macrophages, suggesting that it plays importan...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms21051890

    authors： Kubo M,Nagashima R,Kurihara M,Kawakami F,Maekawa T,Eshima K,Ohta E,Kato H,Obata F

    更新日期：2020-03-10 00:00:00

  • Let-7 in cardiovascular diseases, heart development and cardiovascular differentiation from stem cells.

    abstract：:The let-7 family is the second microRNA found in C. elegans. Recent researches have found it is highly expressed in the cardiovascular system. Studies have revealed the aberrant expression of let-7 members in cardiovascular diseases, such as heart hypertrophy, cardiac fibrosis, dilated cardiomyopathy (DCM), myocardial...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章,评审

    doi：10.3390/ijms141123086

    authors： Bao MH,Feng X,Zhang YW,Lou XY,Cheng Y,Zhou HH

    更新日期：2013-11-21 00:00:00

  • Hypoxia Inducible Factor 1 (HIF-1) Recruits Macrophage to Activate Pancreatic Stellate Cells in Pancreatic Ductal Adenocarcinoma.

    abstract：:Hypoxia inducible factor 1 (HIF-1) is a transcription factor composed of two subunits, namely, HIF-1α and HIF-1β, in which HIF-1β is constitutively expressed. HIF-1 upregulates several hypoxia-responsive proteins, including angiogenesis factors, glycolysis solution enzymes, and cell survival proteins. HIF-1 is also as...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms17060799

    authors： Li N,Li Y,Li Z,Huang C,Yang Y,Lang M,Cao J,Jiang W,Xu Y,Dong J,Ren H

    更新日期：2016-06-03 00:00:00

  • Irradiation-Induced Upregulation of miR-711 Inhibits DNA Repair and Promotes Neurodegeneration Pathways.

    abstract：:Radiotherapy for brain tumors induces neuronal DNA damage and may lead to neurodegeneration and cognitive deficits. We investigated the mechanisms of radiation-induced neuronal cell death and the role of miR-711 in the regulation of these pathways. We used in vitro and in vivo models of radiation-induced neuronal cell...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms21155239

    authors： Sabirzhanov B,Makarevich O,Barrett JP,Jackson IL,Glaser EP,Faden AI,Stoica BA

    更新日期：2020-07-23 00:00:00