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Impact of Trail Running Races on Blood Viscosity and Its Determinants: Effects of Distance.

Abstract：

:Blood rheology is a key determinant of tissue perfusion at rest and during exercise. The present study investigated the effects of race distance on hematological, blood rheological, and red blood cell (RBC) senescence parameters. Eleven runners participated in the Martigny-Combes à Chamonix 40 km race (MCC, elevation gain: 2300 m) and 12 others in the Ultra-Trail du Mont Blanc (UTMB, 171 km, elevation gain: 10,000 m). Blood samples were collected before and after the races. After the UTMB, the percentage of RBC phosphatidylserine (PS) exposure was not affected while RBC CD235a levels decreased and RBC-derived microparticles increased. In contrast, after the MCC, RBC PS exposure increased, while RBC CD235a and RBC-derived microparticles levels were not affected. The free hemoglobin and hemolysis rate did not change during the races. RBC aggregation and blood viscosity at moderate shear rates increased after the MCC. RBC deformability, blood viscosity at a high shear rate, and hematocrit decreased after the UTMB but not after the MCC. Our results indicate that blood rheology behavior is different between a 40 km and a 171 km mountain race. The low blood viscosity after the ultra-marathon might facilitate blood flow to the muscles and optimize aerobic performance.

journal_name

Int J Mol Sci

journal_title

International journal of molecular sciences

authors

Robert M,Stauffer E,Nader E,Skinner S,Boisson C,Cibiel A,Feasson L,Renoux C,Robach P,Joly P,Millet GY,Connes P

doi

10.3390/ijms21228531

subject

Has Abstract

pub_date

2020-11-12 00:00:00

issue

22

issn

1422-0067

pii

ijms21228531

journal_volume

21

pub_type

杂志文章

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