Brain-Specific SNAP-25 Deletion Leads to Elevated Extracellular Glutamate Level and Schizophrenia-Like Behavior in Mice.

abstract：:Increasing research has evidenced that our brain retains a capacity to change in response to experience until late adulthood. This implies that cognitive training can possibly ameliorate age-associated cognitive decline by inducing training-specific neural plastic changes at both neural and behavioral levels. This lon...

journal_title：Neural plasticity

authors： Leung NT,Tam HM,Chu LW,Kwok TC,Chan F,Lam LC,Woo J,Lee TM

更新日期：2015-01-01 00:00:00

abstract：:Elevated brain activation, or hyperexcitability, induces cognitive impairment and confers an increased risk of Alzheimer's disease (AD). Blocking the overexcitation of the neural network may be a promising new strategy to prevent, halt, and even reverse this condition. Physical exercise has been shown to be an effecti...

journal_title：Neural plasticity

authors： Tan YX,Liu GC,Chen HL,Lu MN,Chen B,Hu T,Zhang L,Mao R,Li S,Mei R,Wang XY,Xiyang YB

更新日期：2020-03-18 00:00:00

abstract：:Following central motor lesions, two forms of adaptation can be observed which lead to improved mobility: (1) the development of spastic muscle tone, and (2) the activation of spinal locomotor centers induced by specific treadmill training. Tension development during spastic gait is different from that during normal g...

journal_title：Neural plasticity

authors： Dietz V

更新日期：2001-01-01 00:00:00

abstract：Objective:To determine whether and how longitudinal acupuncture modulates the impaired default mode network (DMN) in chronic migraine (CM) patients without aura. Methods:Resting-state functional magnetic resonance imaging (fMRI) data from 14 CM patients treated with longitudinal pre- and postacupuncture treatment (PPA...

journal_title：Neural plasticity

authors： Zou Y,Tang W,Li X,Xu M,Li J

更新日期：2019-03-18 00:00:00

abstract：:Emotionally arousing events are typically better remembered than mundane ones, in part because emotionally relevant aspects of our environment are prioritized in attention. Such biased attentional tuning is itself the result of associative processes through which we learn affective and motivational relevance of cues. ...

journal_title：Neural plasticity

authors： Ehlers MR,Todd RM

更新日期：2017-01-01 00:00:00

abstract：Background:Surround inhibition is a system that sharpens sensation by creating an inhibitory zone around the central core of activation. In the motor system, this mechanism probably contributes to the selection of voluntary movements, and it seems to be lost in dystonia. Objectives. To explore if sensory information is...

journal_title：Neural plasticity

authors： Terranova C,Rizzo V,Morgante F,Maggio R,Calamuneri A,Chillemi G,Girlanda P,Quartarone A

更新日期：2018-10-10 00:00:00

abstract：:Accumulating evidence implicates a role for brain structures outside the ascending auditory pathway in tinnitus, the phantom perception of sound. In addition to other factors such as age-dependent hearing loss, high-level sound exposure is a prominent cause of tinnitus. Here, we examined how noise exposure altered the...

journal_title：Neural plasticity

authors： Zhang L,Wu C,Martel DT,West M,Sutton MA,Shore SE

更新日期：2021-01-14 00:00:00

abstract：:Adult hippocampal neurogenesis is a process involving the continuous generation of newborn neurons in the hippocampus of adult animals. Mounting evidence has suggested that hippocampal neurogenesis contributes to some forms of hippocampus-dependent learning and memory; however, the detailed mechanism concerning how th...

journal_title：Neural plasticity

authors： Yau SY,Li A,So KF

更新日期：2015-01-01 00:00:00

abstract：:Sustained activation of NLRP3 inflammasome is closely related to diabetes and stroke. However, it is unknown whether NLRP3 inflammasome plays an essential role in stroke in diabetes. We aim to investigate the effect and the potential mechanism of NLRP3 inflammasome in diabetic mice with cerebral ischemia-reperfusion i...

journal_title：Neural plasticity

authors： Hong P,Li FX,Gu RN,Fang YY,Lai LY,Wang YW,Tao T,Xu SY,You ZJ,Zhang HF

更新日期：2018-04-24 00:00:00

abstract：:Embryonic neuroepithelia and adult subventricular zone (SVZ) stem and progenitor cells express nestin. We characterized a transgenic line that expresses enhanced green fluorescent protein (eGFP) specified to neural tissue by the second intronic enhancer of the nestin promoter that had several novel features. During em...

journal_title：Neural plasticity

authors： Walker AS,Goings GE,Kim Y,Miller RJ,Chenn A,Szele FG

更新日期：2010-01-01 00:00:00

abstract：:Traumatic brain injury (TBI) is a worldwide endemic that results in unacceptably high morbidity and mortality. Secondary injury processes following primary injury are composed of intricate interactions between assorted molecules that ultimately dictate the degree of longer-term neurological deficits. One comparatively...

journal_title：Neural plasticity

authors： Budinich CS,Chen H,Lowe D,Rosenberger JG,Bernstock JD,McCabe JT

更新日期：2012-01-01 00:00:00

abstract：:Motoneurons develop extensive dendritic trees for receiving excitatory and inhibitory synaptic inputs to perform a variety of complex motor tasks. At birth, the somatodendritic domains of mouse hypoglossal and lumbar motoneurons have dense filopodia and spines. Consistent with Vaughn's synaptotropic hypothesis, we pro...

journal_title：Neural plasticity

authors： Kanjhan R,Noakes PG,Bellingham MC

更新日期：2016-01-01 00:00:00

abstract：:Several research studies point to the fact that sensory and cognitive reductions like cataracts, deafness, macular degeneration, or even lack of activity after job retirement, precede the onset of Alzheimer's disease. To simulate Alzheimer's disease earlier stages, which manifest in sensory cortices, we used a computa...

journal_title：Neural plasticity

authors： Aguiar-Furucho MA,Peláez FJR

更新日期：2020-10-14 00:00:00

abstract：:Transcranial direct current stimulation (tDCS) can enhance the effect of conventional therapies in post-stroke neurorehabilitation. The ability to predict an individual's potential for tDCS-induced recovery may permit rehabilitation providers to make rational decisions about who will be a good candidate for tDCS thera...

journal_title：Neural plasticity

authors： Baltar A,Piscitelli D,Marques D,Shirahige L,Monte-Silva K

更新日期：2020-11-25 00:00:00

abstract：Background:Despite intensive rehabilitation efforts, most stroke survivors have persistent functional disability of the paretic arm and hand. These motor impairments may be due in part to maladaptive changes in structural and functional connections between brain regions. The following early stage clinical trial study p...

journal_title：Neural plasticity

authors： Borich MR,Wolf SL,Tan AQ,Palmer JA

更新日期：2018-03-12 00:00:00

abstract：:Objective. To explore cortical reorganization of patients recovered from Bell's palsy (BP) by task-state functional magnetic resonance imaging (fMRI) during finger and orofacial movements and provide more evidence for acupuncture clinical treatment of BP. Methods. We collected 17 BP patients with complete clinical rec...

journal_title：Neural plasticity

authors： Lee J,Yang J,Li C,Yuan A,Wu H,Wang A,Xue Q,Wang T,Wang L,Gao T

更新日期：2016-01-01 00:00:00

abstract：:Tinnitus is the phantom perception of sound in the absence of an acoustic stimulus. To date, the purported neural correlates of tinnitus from animal models have not been adequately characterized with translational technology in the human brain. The aim of the present study was to measure changes in oxy-hemoglobin conc...

journal_title：Neural plasticity

authors： Issa M,Bisconti S,Kovelman I,Kileny P,Basura GJ

更新日期：2016-01-01 00:00:00

abstract：:In this study, we attempted to test whether tyrosine hydroxylase (TH), the first rate-limiting enzyme of catecholamine synthesis, is confined to the perikarya of activated magnocellular vasopressinergic (VPergic) neurons or is also present in their distal axons in the pituitary posterior lobe (PL). In addition, we eva...

journal_title：Neural plasticity

authors： Abramova M,Calas A,Thibault J,Ugrumov M

更新日期：2000-01-01 00:00:00

abstract：:We have previously reported the crossed-withdrawal reflex in which the rats with nerve injury developed behavioral pain responses of the injured paw to stimuli applied to the contralateral uninjured paw. This reflex indicates that contralateral plastic changes may occur in the spinal cord after unilateral nerve injury...

journal_title：Neural plasticity

authors： Won R,Lee BH

更新日期：2015-01-01 00:00:00

abstract：:We analyzed operant discrimination in detelencephalated pigeons and neuroanatomical substrates after long-term detelencephalation. In Experiment I, experimental pigeons with massive telencephalic ablation and control pigeons were conditioned to key peck for food. Successive discrimination was made under alternating re...

journal_title：Neural plasticity

authors： Cerutti SM,Diaz-Cintra S,Cintra L,Ferrari EA

更新日期：2003-01-01 00:00:00

abstract：:Success in locomotor rehabilitation programs can be improved with the use of brain-computer interfaces (BCIs). Although a wealth of research has demonstrated that locomotion is largely controlled by spinal mechanisms, the brain is of utmost importance in monitoring locomotor patterns and therefore contains information...

journal_title：Neural plasticity

authors： Cheron G,Duvinage M,De Saedeleer C,Castermans T,Bengoetxea A,Petieau M,Seetharaman K,Hoellinger T,Dan B,Dutoit T,Sylos Labini F,Lacquaniti F,Ivanenko Y

更新日期：2012-01-01 00:00:00

abstract：Background:Bilateral arm training (BAT) has shown promise in expediting progress toward upper limb recovery in chronic stroke patients, but its neural correlates are poorly understood. Objective:To evaluate changes in upper limb function and EEG power after a robot-assisted BAT in chronic stroke patients. Methods:In ...

journal_title：Neural plasticity

authors： Gandolfi M,Formaggio E,Geroin C,Storti SF,Boscolo Galazzo I,Bortolami M,Saltuari L,Picelli A,Waldner A,Manganotti P,Smania N

更新日期：2018-03-26 00:00:00

abstract：:Previous studies have shown that a particular site in the periaqueductal gray (PAG), the rostrolateral PAG, influences the motivation drive to forage or hunt. To have a deeper understanding on the putative paths involved in the decision-making process between foraging, hunting, and other behavioral responses, in the p...

journal_title：Neural plasticity

authors： Mota-Ortiz SR,Sukikara MH,Felicio LF,Canteras NS

更新日期：2009-01-01 00:00:00

abstract：:Inbred mouse models are widely used to study age-related hearing loss (AHL). Many genes associated with AHL have been mapped in a variety of strains. However, little is known about gene variants that have the converse function-protective genes that confer strong resistance to hearing loss. Previously, we reported that...

journal_title：Neural plasticity

authors： Zheng QY,Kui L,Xu F,Zheng T,Li B,McCarty M,Sun Z,Zhang A,Liu L,Starlard-Davenport A,Stepanyan R,Hu BH,Lu L

更新日期：2020-06-08 00:00:00

abstract：:Dichoptic movie viewing has been shown to significantly improve visual acuity in amblyopia in children. Moreover, short-term occlusion of the amblyopic eye can transiently increase its contribution to binocular fusion in adults. In this study, we first asked whether dichoptic movie viewing could improve the visual fun...

journal_title：Neural plasticity

authors： Sauvan L,Stolowy N,Denis D,Matonti F,Chavane F,Hess RF,Reynaud A

更新日期：2019-08-28 00:00:00

abstract：:Histamine H4 receptor has been confirmed to play a role in evoking peripheral pruritus. However, the ionic and intracellular signaling mechanism of activation of H4 receptor on the dorsal root ganglion (DRG) neurons is still unknown. By using cell culture and calcium imaging, we studied the underlying mechanism of act...

journal_title：Neural plasticity

authors： Jian T,Yang N,Yang Y,Zhu C,Yuan X,Yu G,Wang C,Wang Z,Shi H,Tang M,He Q,Lan L,Wu G,Tang Z

更新日期：2016-01-01 00:00:00

abstract：:Freezing of gait (FoG) is among the most disabling symptoms of Parkinson's disease (PD) patients. Recent studies showed that action observation training (AOT) with repetitive practice of the observed actions represents a strategy to induce longer-lasting effects compared with standard physiotherapy. We investigated wh...

journal_title：Neural plasticity

authors： Pelosin E,Barella R,Bet C,Magioncalda E,Putzolu M,Di Biasio F,Cerulli C,Casaleggio M,Abbruzzese G,Avanzino L

更新日期：2018-05-27 00:00:00

abstract：Background and Purpose:Cancer-related fatigue (CRF) is widely recognized as one of the most common symptoms and side effects of cancer and/or its treatment. However, neuropathological mechanisms contributing to CRF are largely unknown, and the lack of knowledge makes CRF difficult to treat. Recent research has shown di...

journal_title：Neural plasticity

authors： Jiang C,Yang Q,Chen T,Siemionow V,Ranganathan VK,Yan AF,Yue GH

更新日期：2019-06-26 00:00:00

abstract：:The motor and nonmotor symptoms of PD involve several brain regions. However, whether α-syn pathology originating from the SNc can directly lead to the pathological changes in distant cerebral regions and induce PD-related symptoms remains unclear. Here, AAV9-synapsin-mCherry-human SNCA (A53T) was injected into the un...

journal_title：Neural plasticity

authors： Wang QJ,Chen AD,Chen HC,Wang DX,Cai YT,Yin J,Jing YH,Gao LP

更新日期：2020-03-21 00:00:00

abstract：:The development of new strategies to renew and repair neuronal networks using neural plasticity induced by stem cell graft could enable new therapies to cure diseases that were considered lethal until now. In adequate microenvironment a neuronal progenitor must receive molecular signal of a specific cellular context t...

journal_title：Neural plasticity

authors： Ramírez-Barrantes R,Cordova C,Poblete H,Muñoz P,Marchant I,Wianny F,Olivero P

更新日期：2016-01-01 00:00:00