An Age-Related Hearing Protection Locus on Chromosome 16 of BXD Strain Mice.

abstract：:Cerebral palsy (CP) has long been investigated to be associated with a range of motor and cognitive dysfunction. As the two most common CP subtypes, spastic cerebral palsy (SCP) and dyskinetic cerebral palsy (DCP) may share common and distinct elements in their pathophysiology. However, the common and distinct dysfunc...

journal_title：Neural plasticity

authors： Qin Y,Li Y,Sun B,He H,Peng R,Zhang T,Li J,Luo C,Sun C,Yao D

更新日期：2018-08-15 00:00:00

abstract：:Despite the fact that astrocytes are the most abundant glial cells, critical for brain function, few studies have dealt with their possible role in neurodegenerative diseases like Parkinson's disease (PD). This article explores relevant evidence on the involvement of astrocytes in experimental PD neurodegeneration fro...

journal_title：Neural plasticity

authors： Udovin L,Quarracino C,Herrera MI,Capani F,Otero-Losada M,Perez-Lloret S

更新日期：2020-02-07 00:00:00

abstract：:Recently, transcranial alternating current stimulation (tACS) has emerged as a tool to enhance human cognitive processes. Here, we provide a brief summary of the rationale behind tACS-induced effects on task-relevant brain oscillations and associated cognitive functions and review previous studies in young subjects th...

journal_title：Neural plasticity

authors： Antonenko D,Faxel M,Grittner U,Lavidor M,Flöel A

更新日期：2016-01-01 00:00:00

abstract：:Matricellular proteins are secreted, nonstructural proteins that regulate the extracellular matrix (ECM) and interactions between cells through modulation of growth factor signaling, cell adhesion, migration, and proliferation. Despite being well described in the context of nonneuronal tissues, recent studies have rev...

journal_title：Neural plasticity

authors： Jones EV,Bouvier DS

更新日期：2014-01-01 00:00:00

abstract：:The GABA-withdrawal syndrome (GWS) is a model of local status epilepticus following the interruption of a chronic GABA infusion into the rat somatomotor cortex. GWS is characterized by focal epileptic electroencephalographic discharges and associated contralateral myoclonus. In neocortical slices obtained from GWS rat...

journal_title：Neural plasticity

authors： Silva-Barrat C,Champagnat J,Menini C

更新日期：2000-01-01 00:00:00

abstract：:Studies have shown that, depending on its severity and context, stress can affect neural plasticity. Most related studies focused on synaptic plasticity and long-term potentiation (LTP) of principle cells. However, evidence suggests that following high-frequency stimulation, which induces LTP in principal cells, modif...

journal_title：Neural plasticity

authors： Yarom O,Maroun M,Richter-Levin G

更新日期：2008-01-01 00:00:00

abstract：:Glaucoma is an irreversible blinding eye disease which produces progressive retinal ganglion cell (RGC) loss. Intraocular pressure (IOP) is currently the only modifiable risk factor, and lowering IOP results in reduced risk of progression of the disorder. The endocannabinoid system (ECS) has attracted considerable att...

journal_title：Neural plasticity

authors： Cairns EA,Baldridge WH,Kelly ME

更新日期：2016-01-01 00:00:00

abstract：:The entorhinal cortex (EC) is a nodal and independent mnemonic element of the medial temporal lobe memory circuit as it forms a bidirectional interface between the neocortex and hippocampus. Within the EC, intra- and inter-lamellar associational connections occur via horizontal and columnar projections, respectively. ...

journal_title：Neural plasticity

authors： Ma L,Alonso A,Dickson CT

更新日期：2008-01-01 00:00:00

abstract：:Proper density and morphology of dendritic spines are important for higher brain functions such as learning and memory. However, our knowledge about molecular mechanisms that regulate thedevelopment and maintenance of dendritic spines is limited. We recently reported that cyclin-dependent kinase 5 (Cdk5) is required f...

journal_title：Neural plasticity

authors： Jin X,Sasamoto K,Nagai J,Yamazaki Y,Saito K,Goshima Y,Inoue T,Ohshima T

更新日期：2016-01-01 00:00:00

abstract：:There is a general consensus that sleep is strictly linked to memory, learning, and, in general, to the mechanisms of neural plasticity, and that this link may directly affect recovery processes. In fact, a coherent pattern of empirical findings points to beneficial effect of sleep on learning and plastic processes, a...

journal_title：Neural plasticity

authors： Gorgoni M,D'Atri A,Lauri G,Rossini PM,Ferlazzo F,De Gennaro L

更新日期：2013-01-01 00:00:00

abstract：:Aging is a complex process strongly determined by genetics. Previous reports have shown that the genome of neuronal cells displays somatic genomic mosaicism including DNA copy number variations (CNVs). CNVs represent a significant source of genetic variation in the human genome and have been implicated in several diso...

journal_title：Neural plasticity

authors： Villela D,Suemoto CK,Leite R,Pasqualucci CA,Grinberg LT,Pearson P,Rosenberg C

更新日期：2018-06-28 00:00:00

abstract：:Cyclothiazide (CTZ) has been reported to simultaneously enhance glutamate receptor excitation and inhibit GABAA receptor inhibition, and in turn it evokes epileptiform activities in hippocampal neurons. It has also been shown to acutely induce epileptic seizure behavior in freely moving rats. However, whether CTZ indu...

journal_title：Neural plasticity

authors： Kong S,Cheng Z,Liu J,Wang Y

更新日期：2014-01-01 00:00:00

abstract：:Using functional multineuron imaging with single-cell resolution, we examined how hippocampal networks by themselves change the spatiotemporal patterns of spontaneous activity during the course of emitting spontaneous activity. When extracellular ionic concentrations were changed to those that mimicked in vivo conditi...

journal_title：Neural plasticity

authors： Usami A,Matsuki N,Ikegaya Y

更新日期：2008-01-01 00:00:00

abstract：:Brain cancer is a common type of childhood malignancy, and radiotherapy (RT) is a mainstay of treatment. RT is effective for tumor eradication, and survival rates are high. However, RT damages the brain and disrupts ongoing developmental processes, resulting in debilitating cognitive "late" effects that may take years...

journal_title：Neural plasticity

authors： Rodgers SP,Trevino M,Zawaski JA,Gaber MW,Leasure JL

更新日期：2013-01-01 00:00:00

abstract：:The habituation/cross-habituation test (HaXha) is a spontaneous odor discrimination task that has been used for many decades to evaluate olfactory function in animals. Animals are presented repeatedly with the same odorant after which a new odorant is introduced. The time the animal explores the odor object is measure...

journal_title：Neural plasticity

authors： Coronas-Samano G,Ivanova AV,Verhagen JV

更新日期：2016-01-01 00:00:00

abstract：:Ceramides induce important intracellular signaling pathways, modulating proliferation, migration, apoptosis, and inflammation. However, the relevance of the ceramide metabolism in the reconvalescence phase after stroke is unclear. Besides its well-known property as a selective serotonin reuptake inhibitor, fluoxetine ...

journal_title：Neural plasticity

authors： Brunkhorst R,Friedlaender F,Ferreirós N,Schwalm S,Koch A,Grammatikos G,Toennes S,Foerch C,Pfeilschifter J,Pfeilschifter W

更新日期：2015-01-01 00:00:00

abstract：:Background. Clinically, electroacupuncture (EA) is the most common therapy for aging-related cognitive impairment (CI). However, the underlying pathomechanism remains unidentified. The aims of this study were to observe the effect of EA on cognitive function and explore the potential mechanism by which EA acts on the ...

journal_title：Neural plasticity

authors： Hou Z,Qiu R,Wei Q,Liu Y,Wang M,Mei T,Zhang Y,Song L,Shao X,Shang H,Chen J,Sun Z

更新日期：2020-11-04 00:00:00

abstract：:Noninvasive brain stimulation (NBS), such as repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS), has been used in stroke patients with motor impairment. NBS can help recovery from brain damage by modulating cortical excitability. However, the efficacy of NBS varies am...

journal_title：Neural plasticity

authors： Lee J,Lee A,Kim H,Shin M,Yun SM,Jung Y,Chang WH,Kim YH

更新日期：2019-04-07 00:00:00

abstract：:Postural problems play a central role in the motor dysfunction of children with cerebral palsy (CP). Therefore, they spend more time in sitting than in standing to perform vital tasks of daily life. The focus of this article is to describe the pathophysiology of postural control in sitting and outline some implication...

journal_title：Neural plasticity

authors： Carlberg EB,Hadders-Algra M

更新日期：2005-01-01 00:00:00

abstract：:The aim of the present study was to assess the role of action observation treatment (AOT) in the rehabilitation of upper limb motor functions in children with cerebral palsy. We carried out a two-group, parallel randomized controlled trial. Eighteen children (aged 5-11 yr) entered the study: 11 were treated children, ...

journal_title：Neural plasticity

authors： Buccino G,Molinaro A,Ambrosi C,Arisi D,Mascaro L,Pinardi C,Rossi A,Gasparotti R,Fazzi E,Galli J

更新日期：2018-07-04 00:00:00

abstract：:The endocannabinoids N-arachidonoylethanolamide (or anandamide, AEA) and 2-arachidonoylglycerol (2-AG) belong to the larger groups of N-acylethanolamines (NAEs) and monoacylglycerol (MAG) lipid classes, respectively. They are biologically active lipid molecules that activate G-protein-coupled cannabinoid receptors fou...

journal_title：Neural plasticity

authors： Keereetaweep J,Chapman KD

更新日期：2016-01-01 00:00:00

abstract：:Although many studies have investigated the functions of histidine triad nucleotide-binding protein 1 (HINT1), its roles in neurobiological processes remain to be fully elucidated. As a member of the histidine triad (HIT) enzyme superfamily, HINT1 is distributed in almost every organ and has both enzymatic and nonenzy...

journal_title：Neural plasticity

authors： Liu P,Liu Z,Wang J,Ma X,Dang Y

更新日期：2017-01-01 00:00:00

abstract：:In this study, we attempted to test whether tyrosine hydroxylase (TH), the first rate-limiting enzyme of catecholamine synthesis, is confined to the perikarya of activated magnocellular vasopressinergic (VPergic) neurons or is also present in their distal axons in the pituitary posterior lobe (PL). In addition, we eva...

journal_title：Neural plasticity

authors： Abramova M,Calas A,Thibault J,Ugrumov M

更新日期：2000-01-01 00:00:00

abstract：:The stria vascularis (SV) generates the endocochlear potential (EP) in the inner ear and is necessary for proper hair cell (HC) mechanotransduction and hearing. Cell junctions are indispensable for the establishment of compositionally distinct fluid compartments in the inner ear. Ototoxic drug cisplatin can damage SV ...

journal_title：Neural plasticity

authors： Zhang N,Cai J,Xu L,Wang H,Liu W

更新日期：2020-09-22 00:00:00

abstract：:Autosomal dominant nonsyndromic hearing loss (ADNSHL) is extremely heterogeneous. So far the genetic etiological contribution of the gene POU4F3 associated with ADNSHL has been rarely reported. In our previous study, a c.603_604delGG mutation in the hair cell specific gene POU4F3 has been identified as the pathogenic ...

journal_title：Neural plasticity

authors： He L,Pang X,Chen P,Wu H,Yang T

更新日期：2016-01-01 00:00:00

abstract：:One major goal in Neuroscience is the development of strategies promoting neural plasticity in the adult central nervous system, when functional recovery from brain disease and injury is limited. New evidence has underscored a pivotal role for cortical inhibitory circuitries in regulating plasticity both during develo...

journal_title：Neural plasticity

authors： Baroncelli L,Braschi C,Spolidoro M,Begenisic T,Maffei L,Sale A

更新日期：2011-01-01 00:00:00

abstract：:Alzheimer's disease (AD) is the most common form of dementia in elderly people. It is an irreversible and progressive brain disease. In this paper, we utilized diffusion-weighted imaging (DWI) to detect abnormal topological organization of white matter (WM) structural networks. We compared the differences between WM c...

journal_title：Neural plasticity

authors： Wang T,Shi F,Jin Y,Yap PT,Wee CY,Zhang J,Yang C,Li X,Xiao S,Shen D

更新日期：2016-01-01 00:00:00

abstract：:Benzodiazepines are well established as inhibitory modulators of memory processing. This effect is especially prominent when applied before the acquisition phase of a memory task. This minireview concentrates on the putative subtype selectivity of the acquisition-impairing action of benzodiazepines. Namely, recent gen...

journal_title：Neural plasticity

authors： Savić MM,Obradović DI,Ugresić ND,Bokonjić DR

更新日期：2005-01-01 00:00:00

abstract：:Magnetic resonance imaging (MRI) of the human brain has provided converging evidence that visual deprivation induces regional changes in white matter (WM) microstructure. It remains unclear how these changes modify network connections between brain regions. Here we used diffusion-weighted MRI to relate differences in ...

journal_title：Neural plasticity

authors： Reislev NL,Dyrby TB,Siebner HR,Kupers R,Ptito M

更新日期：2016-01-01 00:00:00

abstract：:Stress can cause a variety of central nervous system disorders, which are critically mediated by the γ-aminobutyric acid (GABA) system in various brain structures. GABAergic neurons have different subsets, some of which coexpress certain neuropeptides that can be found in the digestive system. Accumulating evidence de...

journal_title：Neural plasticity

authors： Hou X,Rong C,Wang F,Liu X,Sun Y,Zhang HT

更新日期：2020-08-01 00:00:00