Multilevel Deficiency of White Matter Connectivity Networks in Alzheimer's Disease: A Diffusion MRI Study with DTI and HARDI Models.

abstract：:Following central motor lesions, two forms of adaptation can be observed which lead to improved mobility: (1) the development of spastic muscle tone, and (2) the activation of spinal locomotor centers induced by specific treadmill training. Tension development during spastic gait is different from that during normal g...

journal_title：Neural plasticity

authors： Dietz V

更新日期：2001-01-01 00:00:00

abstract：:The plasticity of brain function, especially reorganization after stroke or sensory loss, has been investigated extensively. Based upon its special characteristics, the olfactory system allows the investigation of functional networks in patients with smell loss, as it holds the unique ability to be activated by the se...

journal_title：Neural plasticity

authors： Kollndorfer K,Kowalczyk K,Hoche E,Mueller CA,Pollak M,Trattnig S,Schöpf V

更新日期：2014-01-01 00:00:00

abstract：:Glaucoma is an irreversible blinding eye disease which produces progressive retinal ganglion cell (RGC) loss. Intraocular pressure (IOP) is currently the only modifiable risk factor, and lowering IOP results in reduced risk of progression of the disorder. The endocannabinoid system (ECS) has attracted considerable att...

journal_title：Neural plasticity

authors： Cairns EA,Baldridge WH,Kelly ME

更新日期：2016-01-01 00:00:00

abstract：:Alzheimer's disease (AD) is one of the most serious public health concerns facing the world. Its characteristic feature is neuroinflammation due to microglial activation. Electroacupuncture is one of the therapies employed to improve the condition of patients with AD, although its mechanism of action is still to be de...

journal_title：Neural plasticity

authors： Li Y,Jiang J,Tang Q,Tian H,Wang S,Wang Z,Liu H,Yang J,Ren J

更新日期：2020-09-04 00:00:00

abstract：:The development of new strategies to renew and repair neuronal networks using neural plasticity induced by stem cell graft could enable new therapies to cure diseases that were considered lethal until now. In adequate microenvironment a neuronal progenitor must receive molecular signal of a specific cellular context t...

journal_title：Neural plasticity

authors： Ramírez-Barrantes R,Cordova C,Poblete H,Muñoz P,Marchant I,Wianny F,Olivero P

更新日期：2016-01-01 00:00:00

abstract：:Stimulating regeneration in the brain has the potential to rescue neuronal networks and counteract progressive pathological changes in Alzheimer's disease (AD). This study investigated whether drugs with different mechanisms of action could enhance neurogenesis and improve cognition in mice receiving human neural stem...

journal_title：Neural plasticity

authors： Lilja AM,Malmsten L,Röjdner J,Voytenko L,Verkhratsky A,Ögren SO,Nordberg A,Marutle A

更新日期：2015-01-01 00:00:00

abstract：:Synaptopathies are diseases with synapse defects as shared pathogenic features, encompassing neurodegenerative disorders such as Parkinson's disease (PD). In sporadic PD, the most common age-related neurodegenerative movement disorder, nigrostriatal dopaminergic deficits are responsible for the onset of motor symptoms...

journal_title：Neural plasticity

authors： Longhena F,Faustini G,Missale C,Pizzi M,Spano P,Bellucci A

更新日期：2017-01-01 00:00:00

abstract：:Dopamine (DA) modulates glutamatergic synaptic transmission and its plasticity in the striatum; however it is not well known how DA modulates long-term plasticity of striatal GABAergic inhibitory synapses. This work focused on the analysis of both dopaminergic modulation of inhibitory synapses and the synaptic plastic...

journal_title：Neural plasticity

authors： Nieto Mendoza E,Hernández Echeagaray E

更新日期：2015-01-01 00:00:00

abstract：:We analyzed operant discrimination in detelencephalated pigeons and neuroanatomical substrates after long-term detelencephalation. In Experiment I, experimental pigeons with massive telencephalic ablation and control pigeons were conditioned to key peck for food. Successive discrimination was made under alternating re...

journal_title：Neural plasticity

authors： Cerutti SM,Diaz-Cintra S,Cintra L,Ferrari EA

更新日期：2003-01-01 00:00:00

abstract：:The objective of this study was to assess the evolution of diffusion-weighted imaging (DWI) and diffusion-tensor imaging (DTI) over the first month of life in asphyxiated newborns treated with hypothermia and to compare it with that of healthy newborns. Asphyxiated newborns treated with hypothermia were enrolled prosp...

journal_title：Neural plasticity

authors： Kwan S,Boudes E,Benseler A,Gilbert G,Saint-Martin C,Shevell M,Wintermark P

更新日期：2015-01-01 00:00:00

abstract：:High-frequency synchronization has been found in many real neural systems and is confirmed by excitatory/inhibitory (E/I) network models. However, the functional role played by it remains elusive. In this paper, it is found that high-frequency synchronization in E/I neuronal networks could improve the firing rate cont...

journal_title：Neural plasticity

authors： Han F,Wang Z,Fan H,Zhang Y

更新日期：2020-11-09 00:00:00

abstract：Background:Previous reviews have generally reported cognitive//behavioral improvements after cognitively oriented treatments (COTs) in persons with MCI. However, comparatively little is known about the neural mechanisms associated with such cognitive improvement. Objective:The primary aim of the current review was to ...

journal_title：Neural plasticity

authors： Miotto EC,Batista AX,Simon SS,Hampstead BM

更新日期：2018-12-02 00:00:00

abstract：:Traumatic brain injury (TBI) is a serious medical and social problem worldwide. Because of the complex pathophysiological mechanisms of TBI, effective pharmacotherapy is still lacking. The microglial cells are resident tissue macrophages located in the brain and have two major polarization states, M1 phenotype and M2 ...

journal_title：Neural plasticity

authors： Xu H,Wang Z,Li J,Wu H,Peng Y,Fan L,Chen J,Gu C,Yan F,Wang L,Chen G

更新日期：2017-01-01 00:00:00

abstract：:The entorhinal cortex (EC) is a nodal and independent mnemonic element of the medial temporal lobe memory circuit as it forms a bidirectional interface between the neocortex and hippocampus. Within the EC, intra- and inter-lamellar associational connections occur via horizontal and columnar projections, respectively. ...

journal_title：Neural plasticity

authors： Ma L,Alonso A,Dickson CT

更新日期：2008-01-01 00:00:00

abstract：:Neuropathies are characterized by a complex response of the central nervous system to injuries. Glial cells are recruited to maintain neuronal homeostasis but dysregulated activation leads to pain signaling amplification and reduces the glial neuroprotective power. Recently, we highlighted the property of α7 nicotinic...

journal_title：Neural plasticity

authors： Di Cesare Mannelli L,Tenci B,Zanardelli M,Failli P,Ghelardini C

更新日期：2015-01-01 00:00:00

abstract：:Prenatal stress (PS) has long-term sequelae for the morphological and functional status of the central nervous system of the progeny. A PS-induced proinflammatory status of the organism may result in an impairment of both hippocampal synaptic plasticity and hippocampus-dependent memory formation in adults. We addresse...

journal_title：Neural plasticity

authors： Grigoryan G,Lonnemann N,Korte M

更新日期：2019-01-21 00:00:00

abstract：:Neurophysiological and neuroimaging data suggest that the brains of not only children but also adults are reorganized based on sensory inputs and behaviors. Plastic changes in the brain are generally beneficial; however, maladaptive cortical reorganization in the auditory cortex may lead to hearing disorders such as t...

journal_title：Neural plasticity

authors： Okamoto H

更新日期：2018-05-20 00:00:00

abstract：:Motoneurons develop extensive dendritic trees for receiving excitatory and inhibitory synaptic inputs to perform a variety of complex motor tasks. At birth, the somatodendritic domains of mouse hypoglossal and lumbar motoneurons have dense filopodia and spines. Consistent with Vaughn's synaptotropic hypothesis, we pro...

journal_title：Neural plasticity

authors： Kanjhan R,Noakes PG,Bellingham MC

更新日期：2016-01-01 00:00:00

abstract：:Most citizen people are exposed daily to environmental noise at moderate levels with a short duration. The aim of the present study was to determine the effects of daily short-term exposure to moderate noise on sound level processing in the auditory midbrain. Sound processing properties of auditory midbrain neurons we...

journal_title：Neural plasticity

authors： Cheng L,Wang SH,Peng K,Liao XM

更新日期：2017-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2017/6724631.]. ...

journal_title：Neural plasticity

authors： Binda P,Lunghi C

更新日期：2017-01-01 00:00:00

abstract：:Embryonic neuroepithelia and adult subventricular zone (SVZ) stem and progenitor cells express nestin. We characterized a transgenic line that expresses enhanced green fluorescent protein (eGFP) specified to neural tissue by the second intronic enhancer of the nestin promoter that had several novel features. During em...

journal_title：Neural plasticity

authors： Walker AS,Goings GE,Kim Y,Miller RJ,Chenn A,Szele FG

更新日期：2010-01-01 00:00:00

abstract：:Although quantitative analysis of the sleep electroencephalogram (EEG) has uncovered important aspects of brain activity during sleep in adolescents and adults, similar findings from preschool-age children remain scarce. This study utilized our time-frequency method to examine sleep oscillations as characteristic feat...

journal_title：Neural plasticity

authors： Olbrich E,Rusterholz T,LeBourgeois MK,Achermann P

更新日期：2017-01-01 00:00:00

abstract：:Homeostatic synaptic plasticity is a negative-feedback response employed to compensate for functional disturbances in the nervous system. Typically, synaptic activity is strengthened when neuronal firing is chronically suppressed or weakened when neuronal activity is chronically elevated. At both the whole cell and en...

journal_title：Neural plasticity

authors： Wang G,Gilbert J,Man HY

更新日期：2012-01-01 00:00:00

abstract：:Recently several lines of evidence demonstrated that methylcobalamin (MeCbl) might have potential analgesic effect in experimental and clinical studies. However, it was reported that MeCbl had no effect on treating lumbar spinal stenosis induced pain. Thus, the effects of short-term and long-term administration of MeC...

journal_title：Neural plasticity

authors： Zhang M,Han W,Zheng J,Meng F,Jiao X,Hu S,Xu H

更新日期：2015-01-01 00:00:00

abstract：:Success in locomotor rehabilitation programs can be improved with the use of brain-computer interfaces (BCIs). Although a wealth of research has demonstrated that locomotion is largely controlled by spinal mechanisms, the brain is of utmost importance in monitoring locomotor patterns and therefore contains information...

journal_title：Neural plasticity

authors： Cheron G,Duvinage M,De Saedeleer C,Castermans T,Bengoetxea A,Petieau M,Seetharaman K,Hoellinger T,Dan B,Dutoit T,Sylos Labini F,Lacquaniti F,Ivanenko Y

更新日期：2012-01-01 00:00:00

abstract：:We have previously shown that spontaneous release of glutamate in the entorhinal cortex (EC) is tonically facilitated via activation of presynaptic NMDA receptors (NMDAr) containing the NR2B subunit. Here we show that the same receptors mediate short-term plasticity manifested by frequency-dependent facilitation of ev...

journal_title：Neural plasticity

authors： Chamberlain SE,Yang J,Jones RS

更新日期：2008-01-01 00:00:00

abstract：:Adult hippocampal neurogenesis is a process involving the continuous generation of newborn neurons in the hippocampus of adult animals. Mounting evidence has suggested that hippocampal neurogenesis contributes to some forms of hippocampus-dependent learning and memory; however, the detailed mechanism concerning how th...

journal_title：Neural plasticity

authors： Yau SY,Li A,So KF

更新日期：2015-01-01 00:00:00

abstract：:Rapidly emerging evidence implicates perineuronal nets (PNNs) and extracellular matrix (ECM) molecules that compose or interact with PNNs, in the pathophysiology of several psychiatric disorders. Studies on schizophrenia, autism spectrum disorders, mood disorders, Alzheimer's disease, and epilepsy point to the involve...

journal_title：Neural plasticity

authors： Pantazopoulos H,Berretta S

更新日期：2016-01-01 00:00:00

abstract：:With the rise in the aging global population, stroke comorbidities have become a serious health threat and a tremendous economic burden on human society. Current therapeutic strategies mainly focus on protecting neurons from cytotoxic damage at the acute phase upon stroke onset, which not only is a difficult way to am...

journal_title：Neural plasticity

authors： Liu W,Wang X,O'Connor M,Wang G,Han F

更新日期：2020-01-27 00:00:00

abstract：:Several studies have associated reduced expression of synaptosomal-associated protein of 25 kDa (SNAP-25) with schizophrenia, yet little is known about its role in the illness. In this paper, a forebrain glutamatergic neuron-specific SNAP-25 knockout mouse model was constructed and studied to explore the possible path...

journal_title：Neural plasticity

authors： Yang H,Zhang M,Shi J,Zhou Y,Wan Z,Wang Y,Wan Y,Li J,Wang Z,Fei J

更新日期：2017-01-01 00:00:00