Involvement of Adult Hippocampal Neurogenesis in Learning and Forgetting.

abstract：:Evidence from neuropathological, genetic, animal model, and biochemical studies has indicated that the accumulation of amyloid-beta (Aβ) is associated with, and probably induces, profound neuronal changes in brain regions critical for memory and cognition in the development of Alzheimer's disease (AD). There is consid...

journal_title：Neural plasticity

authors： Guntupalli S,Widagdo J,Anggono V

更新日期：2016-01-01 00:00:00

abstract：:Ceramides induce important intracellular signaling pathways, modulating proliferation, migration, apoptosis, and inflammation. However, the relevance of the ceramide metabolism in the reconvalescence phase after stroke is unclear. Besides its well-known property as a selective serotonin reuptake inhibitor, fluoxetine ...

journal_title：Neural plasticity

authors： Brunkhorst R,Friedlaender F,Ferreirós N,Schwalm S,Koch A,Grammatikos G,Toennes S,Foerch C,Pfeilschifter J,Pfeilschifter W

更新日期：2015-01-01 00:00:00

abstract：:Despite the fact that astrocytes are the most abundant glial cells, critical for brain function, few studies have dealt with their possible role in neurodegenerative diseases like Parkinson's disease (PD). This article explores relevant evidence on the involvement of astrocytes in experimental PD neurodegeneration fro...

journal_title：Neural plasticity

authors： Udovin L,Quarracino C,Herrera MI,Capani F,Otero-Losada M,Perez-Lloret S

更新日期：2020-02-07 00:00:00

abstract：:When activated, metabotropic glutamate receptors (mGlus) exert long-lasting changes within the glutamatergic synapses. One mechanism is a tonic effect of downstream signal transduction pathways via sustained activation of mGlu itself. Like many other G protein-coupled receptors (GPCRs), mGlu can exist in a constitutiv...

journal_title：Neural plasticity

authors： Chung G,Kim SJ

更新日期：2017-01-01 00:00:00

abstract：Background:Feedback postural control depends upon information from somatosensation, vision, and the vestibular system that are weighted depending on their relative importance within the central nervous system. Following loss of any sensory component, the weighting changes, e.g., when suffering a vestibular loss, the mo...

journal_title：Neural plasticity

authors： Tjernström F,Fransson PA,Kahlon B,Karlberg M,Lindberg S,Siesjö P,Magnusson M

更新日期：2019-02-18 00:00:00

abstract：:Memory is our ability to store and remember past experiences; it is the result of changes in neuronal circuits of specific brain areas as the hippocampus. During memory formation, neurons integrate their functions and increase the strength of their connections, so that synaptic plasticity is improved and consolidated....

journal_title：Neural plasticity

authors： Colciago A,Magnaghi V

更新日期：2016-01-01 00:00:00

abstract：:Transcranial direct current stimulation (tDCS) can enhance the effect of conventional therapies in post-stroke neurorehabilitation. The ability to predict an individual's potential for tDCS-induced recovery may permit rehabilitation providers to make rational decisions about who will be a good candidate for tDCS thera...

journal_title：Neural plasticity

authors： Baltar A,Piscitelli D,Marques D,Shirahige L,Monte-Silva K

更新日期：2020-11-25 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2017/6724631.]. ...

journal_title：Neural plasticity

authors： Binda P,Lunghi C

更新日期：2017-01-01 00:00:00

abstract：:Proper functioning of the visual system depends on maturation of both excitatory and inhibitory synapses within the visual cortex. Considering that perisomatic inhibition is one of the key factors that control the critical period in visual cortex, it is pertinent to understand its regulation by visual experience. To d...

journal_title：Neural plasticity

authors： Kreczko A,Goel A,Song L,Lee HK

更新日期：2009-01-01 00:00:00

abstract：:Damage to the visual system can result in (a partial) loss of vision, in response to which the visual system may functionally reorganize. Yet the timing, extent, and conditions under which this occurs are not well understood. Hence, studies in individuals with diverse congenital and acquired conditions and using vario...

journal_title：Neural plasticity

authors： Halbertsma HN,Haak KV,Cornelissen FW

更新日期：2019-09-03 00:00:00

abstract：:Functional and morphological studies in children affected by Attention Deficit Hyperactivity Disorder (ADHD) suggest a prefrontal cortex (PFc) dysfunction. This cortical region is regulated by subcortical systems including noradrenergic (NEergic), dopaminergic (DAergic), cholinergic, serotonergic, and histaminergic pa...

journal_title：Neural plasticity

authors： Viggiano D,Ruocco LA,Arcieri S,Sadile AG

更新日期：2004-01-01 00:00:00

abstract：Background:Despite intensive rehabilitation efforts, most stroke survivors have persistent functional disability of the paretic arm and hand. These motor impairments may be due in part to maladaptive changes in structural and functional connections between brain regions. The following early stage clinical trial study p...

journal_title：Neural plasticity

authors： Borich MR,Wolf SL,Tan AQ,Palmer JA

更新日期：2018-03-12 00:00:00

abstract：:Synaptopathies are diseases with synapse defects as shared pathogenic features, encompassing neurodegenerative disorders such as Parkinson's disease (PD). In sporadic PD, the most common age-related neurodegenerative movement disorder, nigrostriatal dopaminergic deficits are responsible for the onset of motor symptoms...

journal_title：Neural plasticity

authors： Longhena F,Faustini G,Missale C,Pizzi M,Spano P,Bellucci A

更新日期：2017-01-01 00:00:00

abstract：:Transcranial Direct Current Stimulation (tDCS) is an emerging tool to improve upper limb motor functions after stroke acquired in adulthood; however, there is a paucity of reports on its efficacy for upper limb motor rehabilitation in congenital or early-acquired stroke. In this pilot study we have explored, for the f...

journal_title：Neural plasticity

authors： Inguaggiato E,Bolognini N,Fiori S,Cioni G

更新日期：2019-01-15 00:00:00

abstract：:Success in locomotor rehabilitation programs can be improved with the use of brain-computer interfaces (BCIs). Although a wealth of research has demonstrated that locomotion is largely controlled by spinal mechanisms, the brain is of utmost importance in monitoring locomotor patterns and therefore contains information...

journal_title：Neural plasticity

authors： Cheron G,Duvinage M,De Saedeleer C,Castermans T,Bengoetxea A,Petieau M,Seetharaman K,Hoellinger T,Dan B,Dutoit T,Sylos Labini F,Lacquaniti F,Ivanenko Y

更新日期：2012-01-01 00:00:00

abstract：:Neuropathic pain increases the risk of cardiovascular diseases including hypertension with the characteristic of sympathetic overactivity. The enhanced tonically active glutamatergic input to the rostral ventrolateral medulla (RVLM) contributes to sympathetic overactivity and blood pressure (BP) in cardiovascular dise...

journal_title：Neural plasticity

authors： Wang W,Zou Z,Tan X,Zhang RW,Ren CZ,Yao XY,Li CB,Wang WZ,Shi XY

更新日期：2017-01-01 00:00:00

abstract：:The GABA-withdrawal syndrome (GWS) is a model of local status epilepticus following the interruption of a chronic GABA infusion into the rat somatomotor cortex. GWS is characterized by focal epileptic electroencephalographic discharges and associated contralateral myoclonus. In neocortical slices obtained from GWS rat...

journal_title：Neural plasticity

authors： Silva-Barrat C,Champagnat J,Menini C

更新日期：2000-01-01 00:00:00

abstract：:Neurogenesis in the hippocampus is influenced by several factors including external stimuli. In addition to their involvement in learning and memory processes, newborn neurons of the dentate gyrus (DG) buffer against the effects of stress. Although the response of these cells to environmental stimuli has been shown, t...

journal_title：Neural plasticity

authors： Ramírez-Rodríguez GB,Ocaña-Fernández MDÁ,Ortiz-López L

更新日期：2018-05-22 00:00:00

abstract：:The endocannabinoids N-arachidonoylethanolamide (or anandamide, AEA) and 2-arachidonoylglycerol (2-AG) belong to the larger groups of N-acylethanolamines (NAEs) and monoacylglycerol (MAG) lipid classes, respectively. They are biologically active lipid molecules that activate G-protein-coupled cannabinoid receptors fou...

journal_title：Neural plasticity

authors： Keereetaweep J,Chapman KD

更新日期：2016-01-01 00:00:00

abstract：:Dichoptic movie viewing has been shown to significantly improve visual acuity in amblyopia in children. Moreover, short-term occlusion of the amblyopic eye can transiently increase its contribution to binocular fusion in adults. In this study, we first asked whether dichoptic movie viewing could improve the visual fun...

journal_title：Neural plasticity

authors： Sauvan L,Stolowy N,Denis D,Matonti F,Chavane F,Hess RF,Reynaud A

更新日期：2019-08-28 00:00:00

abstract：:The formation of the complex cerebellar cortical circuits follows different phases, with initial synaptogenesis and subsequent processes of refinement guided by a variety of mechanisms. The regularity of the cellular and synaptic organization of the cerebellar cortex allowed detailed studies of the structural plastici...

journal_title：Neural plasticity

authors： Hoxha E,Lippiello P,Scelfo B,Tempia F,Ghirardi M,Miniaci MC

更新日期：2017-01-01 00:00:00

abstract：:High-frequency synchronization has been found in many real neural systems and is confirmed by excitatory/inhibitory (E/I) network models. However, the functional role played by it remains elusive. In this paper, it is found that high-frequency synchronization in E/I neuronal networks could improve the firing rate cont...

journal_title：Neural plasticity

authors： Han F,Wang Z,Fan H,Zhang Y

更新日期：2020-11-09 00:00:00

abstract：:Inhibitors of HMG-CoA reductase (statins), widely used to lower cholesterol in coronary heart and vascular disease, are effective drugs in reducing the risk of stroke and improving its outcome in the long term. After ischemic stroke, cardiac autonomic dysfunction and psychological problems are common complications rel...

journal_title：Neural plasticity

authors： Cho KJ,Cheon SY,Kim GW

更新日期：2015-01-01 00:00:00

abstract：:Background. Clinically, electroacupuncture (EA) is the most common therapy for aging-related cognitive impairment (CI). However, the underlying pathomechanism remains unidentified. The aims of this study were to observe the effect of EA on cognitive function and explore the potential mechanism by which EA acts on the ...

journal_title：Neural plasticity

authors： Hou Z,Qiu R,Wei Q,Liu Y,Wang M,Mei T,Zhang Y,Song L,Shao X,Shang H,Chen J,Sun Z

更新日期：2020-11-04 00:00:00

abstract：:Temporary functional deafferentation (TFD) by an anesthetic cream on the stroke-affected forearm was shown to improve sensorimotor abilities of stroke patients. The present study investigated different predictors for sensorimotor improvements during TFD and indicated outcome differences between patients grouped in sub...

journal_title：Neural plasticity

authors： Sens E,Franz M,Preul C,Meissner W,Witte OW,Miltner WHR,Weiss T

更新日期：2018-07-29 00:00:00

abstract：:Traumatic brain injury (TBI) is a serious medical and social problem worldwide. Because of the complex pathophysiological mechanisms of TBI, effective pharmacotherapy is still lacking. The microglial cells are resident tissue macrophages located in the brain and have two major polarization states, M1 phenotype and M2 ...

journal_title：Neural plasticity

authors： Xu H,Wang Z,Li J,Wu H,Peng Y,Fan L,Chen J,Gu C,Yan F,Wang L,Chen G

更新日期：2017-01-01 00:00:00

abstract：:The role of the right hemisphere (RH) in recovery from aphasia is incompletely understood. The present study quantified RH grey matter (GM) volume in individuals with chronic stroke-induced aphasia and cognitively healthy people using voxel-based morphometry. We compared group differences in GM volume in the entire RH...

journal_title：Neural plasticity

authors： Lukic S,Barbieri E,Wang X,Caplan D,Kiran S,Rapp B,Parrish TB,Thompson CK

更新日期：2017-01-01 00:00:00

abstract：:Tinnitus is the phantom perception of sound in the absence of an acoustic stimulus. To date, the purported neural correlates of tinnitus from animal models have not been adequately characterized with translational technology in the human brain. The aim of the present study was to measure changes in oxy-hemoglobin conc...

journal_title：Neural plasticity

authors： Issa M,Bisconti S,Kovelman I,Kileny P,Basura GJ

更新日期：2016-01-01 00:00:00

abstract：:Alzheimer's disease (AD) is the most common form of dementia in the elderly; important risk factors are old age and inheritance of the apolipoprotein E4 (APOE4) allele. Changes in amyloid precursor protein (APP) binding, trafficking, and sorting may be important AD causative factors. Secretase-mediated APP cleavage pr...

journal_title：Neural plasticity

authors： Zollo A,Allen Z,Rasmussen HF,Iannuzzi F,Shi Y,Larsen A,Maier TJ,Matrone C

更新日期：2017-01-01 00:00:00

abstract：:Neuropathies are characterized by a complex response of the central nervous system to injuries. Glial cells are recruited to maintain neuronal homeostasis but dysregulated activation leads to pain signaling amplification and reduces the glial neuroprotective power. Recently, we highlighted the property of α7 nicotinic...

journal_title：Neural plasticity

authors： Di Cesare Mannelli L,Tenci B,Zanardelli M,Failli P,Ghelardini C

更新日期：2015-01-01 00:00:00