Visual deprivation decreases somatic GAD65 puncta number on layer 2/3 pyramidal neurons in mouse visual cortex.

abstract：:Ciliary neurotrophic factor (CNTF) promotes survival and enhances long-distance regeneration of injured axons in parts of the adult CNS. Here we tested whether CNTF gene therapy targeting corticospinal neurons (CSN) in motor-related regions of the cerebral cortex promotes plasticity and regrowth of axons projecting in...

journal_title：Neural plasticity

authors： Hodgetts SI,Yoon JH,Fogliani A,Akinpelu EA,Baron-Heeris D,Houwers IGJ,Wheeler LPG,Majda BT,Santhakumar S,Lovett SJ,Duce E,Pollett MA,Wiseman TM,Fehily B,Harvey AR

更新日期：2018-08-06 00:00:00

abstract：:Brain cancer is a common type of childhood malignancy, and radiotherapy (RT) is a mainstay of treatment. RT is effective for tumor eradication, and survival rates are high. However, RT damages the brain and disrupts ongoing developmental processes, resulting in debilitating cognitive "late" effects that may take years...

journal_title：Neural plasticity

authors： Rodgers SP,Trevino M,Zawaski JA,Gaber MW,Leasure JL

更新日期：2013-01-01 00:00:00

abstract：:We have previously shown that spontaneous release of glutamate in the entorhinal cortex (EC) is tonically facilitated via activation of presynaptic NMDA receptors (NMDAr) containing the NR2B subunit. Here we show that the same receptors mediate short-term plasticity manifested by frequency-dependent facilitation of ev...

journal_title：Neural plasticity

authors： Chamberlain SE,Yang J,Jones RS

更新日期：2008-01-01 00:00:00

abstract：:The stria vascularis (SV) generates the endocochlear potential (EP) in the inner ear and is necessary for proper hair cell (HC) mechanotransduction and hearing. Cell junctions are indispensable for the establishment of compositionally distinct fluid compartments in the inner ear. Ototoxic drug cisplatin can damage SV ...

journal_title：Neural plasticity

authors： Zhang N,Cai J,Xu L,Wang H,Liu W

更新日期：2020-09-22 00:00:00

abstract：:Introduction. Bipolar disorder (BD) implies risk of suicide. The age at onset (AAO) of BD carries prognostic significance. Substance abuse may precede the onset of BD and cannabis is the most common illicit drug used. The main goal of this study is to review the association of cannabis use as a risk factor for early o...

journal_title：Neural plasticity

authors： Leite RT,Nogueira Sde O,do Nascimento JP,de Lima LS,da Nóbrega TB,Virgínio Mda S,Moreno LM,Sampaio BH,de Matos E Souza FG

更新日期：2015-01-01 00:00:00

abstract：:Ceramides induce important intracellular signaling pathways, modulating proliferation, migration, apoptosis, and inflammation. However, the relevance of the ceramide metabolism in the reconvalescence phase after stroke is unclear. Besides its well-known property as a selective serotonin reuptake inhibitor, fluoxetine ...

journal_title：Neural plasticity

authors： Brunkhorst R,Friedlaender F,Ferreirós N,Schwalm S,Koch A,Grammatikos G,Toennes S,Foerch C,Pfeilschifter J,Pfeilschifter W

更新日期：2015-01-01 00:00:00

abstract：:The motor and nonmotor symptoms of PD involve several brain regions. However, whether α-syn pathology originating from the SNc can directly lead to the pathological changes in distant cerebral regions and induce PD-related symptoms remains unclear. Here, AAV9-synapsin-mCherry-human SNCA (A53T) was injected into the un...

journal_title：Neural plasticity

authors： Wang QJ,Chen AD,Chen HC,Wang DX,Cai YT,Yin J,Jing YH,Gao LP

更新日期：2020-03-21 00:00:00

abstract：:Despite the fact that astrocytes are the most abundant glial cells, critical for brain function, few studies have dealt with their possible role in neurodegenerative diseases like Parkinson's disease (PD). This article explores relevant evidence on the involvement of astrocytes in experimental PD neurodegeneration fro...

journal_title：Neural plasticity

authors： Udovin L,Quarracino C,Herrera MI,Capani F,Otero-Losada M,Perez-Lloret S

更新日期：2020-02-07 00:00:00

abstract：:The endocannabinoids N-arachidonoylethanolamide (or anandamide, AEA) and 2-arachidonoylglycerol (2-AG) belong to the larger groups of N-acylethanolamines (NAEs) and monoacylglycerol (MAG) lipid classes, respectively. They are biologically active lipid molecules that activate G-protein-coupled cannabinoid receptors fou...

journal_title：Neural plasticity

authors： Keereetaweep J,Chapman KD

更新日期：2016-01-01 00:00:00

abstract：Background:Sudden sensorineural hearing loss (SSNHL) is an otologic emergency and could lead to social difficulties and mental disorders in some patients. Although many studies have analyzed altered brain function in populations with hearing loss, little information is available about patients with idiopathic SSNHL. Th...

journal_title：Neural plasticity

authors： Chen J,Hu B,Qin P,Gao W,Liu C,Zi D,Ding X,Yu Y,Cui G,Lu L

更新日期：2020-09-22 00:00:00

abstract：:Histamine H4 receptor has been confirmed to play a role in evoking peripheral pruritus. However, the ionic and intracellular signaling mechanism of activation of H4 receptor on the dorsal root ganglion (DRG) neurons is still unknown. By using cell culture and calcium imaging, we studied the underlying mechanism of act...

journal_title：Neural plasticity

authors： Jian T,Yang N,Yang Y,Zhu C,Yuan X,Yu G,Wang C,Wang Z,Shi H,Tang M,He Q,Lan L,Wu G,Tang Z

更新日期：2016-01-01 00:00:00

abstract：:The development of new strategies to renew and repair neuronal networks using neural plasticity induced by stem cell graft could enable new therapies to cure diseases that were considered lethal until now. In adequate microenvironment a neuronal progenitor must receive molecular signal of a specific cellular context t...

journal_title：Neural plasticity

authors： Ramírez-Barrantes R,Cordova C,Poblete H,Muñoz P,Marchant I,Wianny F,Olivero P

更新日期：2016-01-01 00:00:00

abstract：Background:Previous reviews have generally reported cognitive//behavioral improvements after cognitively oriented treatments (COTs) in persons with MCI. However, comparatively little is known about the neural mechanisms associated with such cognitive improvement. Objective:The primary aim of the current review was to ...

journal_title：Neural plasticity

authors： Miotto EC,Batista AX,Simon SS,Hampstead BM

更新日期：2018-12-02 00:00:00

abstract：Background and Purpose:Cancer-related fatigue (CRF) is widely recognized as one of the most common symptoms and side effects of cancer and/or its treatment. However, neuropathological mechanisms contributing to CRF are largely unknown, and the lack of knowledge makes CRF difficult to treat. Recent research has shown di...

journal_title：Neural plasticity

authors： Jiang C,Yang Q,Chen T,Siemionow V,Ranganathan VK,Yan AF,Yue GH

更新日期：2019-06-26 00:00:00

abstract：Objective:To compare the effects of training of jaw and finger movements with and without visual feedback on precision and accuracy. Method:Twenty healthy participants (10 men and 10 women; mean age 24.6 ± 0.8 years) performed two tasks: a jaw open-close movement and a finger lifting task with and without visual feedb...

journal_title：Neural plasticity

authors： Chen Y,Wu S,Tang Z,Zhang J,Wang L,Yu L,Wang K,Svensson P

更新日期：2019-11-18 00:00:00

abstract：:Matricellular proteins are secreted, nonstructural proteins that regulate the extracellular matrix (ECM) and interactions between cells through modulation of growth factor signaling, cell adhesion, migration, and proliferation. Despite being well described in the context of nonneuronal tissues, recent studies have rev...

journal_title：Neural plasticity

authors： Jones EV,Bouvier DS

更新日期：2014-01-01 00:00:00

abstract：:Chronic stress can impair hippocampal neurogenesis, increase neuronal apoptosis, and cause depressive-like behaviors. Our previous studies found that Radix Scutellariae (RS) can rescue the stress-induced neuronal injury, but the mechanism is not clear. Here, we continued to investigate the underlying antidepressant me...

journal_title：Neural plasticity

authors： Zhao F,Zhang C,Xiao D,Zhang W,Zhou L,Gu S,Qu R

更新日期：2020-11-13 00:00:00

abstract：:Anxiety is most common among Alzheimer's disease (AD) patients with an age at onset under age 65. Apolipoprotein E4 (apoE4) is a risk factor for developing AD at an earlier age and might contribute to this effect. In mice, apoE plays a role in the regulation of anxiety, which might involve histamine receptor-mediated ...

journal_title：Neural plasticity

authors： Raber J

更新日期：2007-01-01 00:00:00

abstract：:Emotionally arousing events are typically better remembered than mundane ones, in part because emotionally relevant aspects of our environment are prioritized in attention. Such biased attentional tuning is itself the result of associative processes through which we learn affective and motivational relevance of cues. ...

journal_title：Neural plasticity

authors： Ehlers MR,Todd RM

更新日期：2017-01-01 00:00:00

abstract：:The current study is aimed at establishing links between brain network examination and neural plasticity studies measured by optical neuroimaging. Sixteen healthy subjects were recruited from the University of Macau to test the Granger Prediction Estimation (GPE) method to investigate brain network connectivity during...

journal_title：Neural plasticity

authors： Couto TA,Xu S,da Silva PA,Wu C,Neergaard K,Wang MY,Zhang J,Xiang Y,Yuan Z

更新日期：2020-10-06 00:00:00

abstract：Background:Parkinson's disease (PD) patients experience cognitive impairment which has been related to reduced quality of life and functional disability. These symptoms usually progress until dementia occurs. Some studies have been published assessing the efficacy of cognitive treatments on improving cognition, functio...

journal_title：Neural plasticity

authors： Díez-Cirarda M,Ibarretxe-Bilbao N,Peña J,Ojeda N

更新日期：2018-05-06 00:00:00

abstract：Background:One in three survivors of stroke experience poststroke depression (PSD). PSD has been linked with poorer recovery of function and cognition, yet our understanding of potential mechanisms is currently limited. Alterations in resting-state functional MRI have been investigated to a limited extent. Fluctuations...

journal_title：Neural plasticity

authors： Goodin P,Lamp G,Vidyasagar R,Connelly A,Rose S,Campbell BCV,Tse T,Ma H,Howells D,Hankey GJ,Davis S,Donnan G,Carey LM

更新日期：2019-07-28 00:00:00

abstract：:Studies on visually deprived individuals provide one of the most striking demonstrations that the brain is highly plastic and is able to rewire as a function of the sensory input it receives from the environment. In the current paper, we focus on spatial abilities that are typically related to the dorsal visual pathwa...

journal_title：Neural plasticity

authors： Dormal G,Lepore F,Collignon O

更新日期：2012-01-01 00:00:00

abstract：Background:Surround inhibition is a system that sharpens sensation by creating an inhibitory zone around the central core of activation. In the motor system, this mechanism probably contributes to the selection of voluntary movements, and it seems to be lost in dystonia. Objectives. To explore if sensory information is...

journal_title：Neural plasticity

authors： Terranova C,Rizzo V,Morgante F,Maggio R,Calamuneri A,Chillemi G,Girlanda P,Quartarone A

更新日期：2018-10-10 00:00:00

abstract：:Evidence suggests that inflammation and neurogenesis play an important role in major depressive disorder (MDD). Mahuang-Fuzi-Xixin decoction (MFX), as the traditional Chinese prescription, has been widely applied for asthma, migraine, and MDD in clinics. However, the effects of MFX on the potential mechanism in MDD ar...

journal_title：Neural plasticity

authors： Jing W,Song S,Sun H,Chen Y,Zhao Q,Zhang Y,Dai G,Ju W

更新日期：2019-11-11 00:00:00

abstract：:Autosomal dominant nonsyndromic hearing loss (ADNSHL) is extremely heterogeneous. So far the genetic etiological contribution of the gene POU4F3 associated with ADNSHL has been rarely reported. In our previous study, a c.603_604delGG mutation in the hair cell specific gene POU4F3 has been identified as the pathogenic ...

journal_title：Neural plasticity

authors： He L,Pang X,Chen P,Wu H,Yang T

更新日期：2016-01-01 00:00:00

abstract：:Success in locomotor rehabilitation programs can be improved with the use of brain-computer interfaces (BCIs). Although a wealth of research has demonstrated that locomotion is largely controlled by spinal mechanisms, the brain is of utmost importance in monitoring locomotor patterns and therefore contains information...

journal_title：Neural plasticity

authors： Cheron G,Duvinage M,De Saedeleer C,Castermans T,Bengoetxea A,Petieau M,Seetharaman K,Hoellinger T,Dan B,Dutoit T,Sylos Labini F,Lacquaniti F,Ivanenko Y

更新日期：2012-01-01 00:00:00

abstract：:Embryonic neuroepithelia and adult subventricular zone (SVZ) stem and progenitor cells express nestin. We characterized a transgenic line that expresses enhanced green fluorescent protein (eGFP) specified to neural tissue by the second intronic enhancer of the nestin promoter that had several novel features. During em...

journal_title：Neural plasticity

authors： Walker AS,Goings GE,Kim Y,Miller RJ,Chenn A,Szele FG

更新日期：2010-01-01 00:00:00

abstract：:Following central motor lesions, two forms of adaptation can be observed which lead to improved mobility: (1) the development of spastic muscle tone, and (2) the activation of spinal locomotor centers induced by specific treadmill training. Tension development during spastic gait is different from that during normal g...

journal_title：Neural plasticity

authors： Dietz V

更新日期：2001-01-01 00:00:00

abstract：:Transcranial direct current stimulation (tDCS) can enhance the effect of conventional therapies in post-stroke neurorehabilitation. The ability to predict an individual's potential for tDCS-induced recovery may permit rehabilitation providers to make rational decisions about who will be a good candidate for tDCS thera...

journal_title：Neural plasticity

authors： Baltar A,Piscitelli D,Marques D,Shirahige L,Monte-Silva K

更新日期：2020-11-25 00:00:00