Human Auditory and Adjacent Nonauditory Cerebral Cortices Are Hypermetabolic in Tinnitus as Measured by Functional Near-Infrared Spectroscopy (fNIRS).

abstract：:Several studies have associated reduced expression of synaptosomal-associated protein of 25 kDa (SNAP-25) with schizophrenia, yet little is known about its role in the illness. In this paper, a forebrain glutamatergic neuron-specific SNAP-25 knockout mouse model was constructed and studied to explore the possible path...

journal_title：Neural plasticity

authors： Yang H,Zhang M,Shi J,Zhou Y,Wan Z,Wang Y,Wan Y,Li J,Wang Z,Fei J

更新日期：2017-01-01 00:00:00

abstract：:Focal hand dystonia (FHd) is a recalcitrant, disabling movement disorder, characterized by involuntary co-contractions of agonists and antagonists, that can develop in patients who overuse or misuse their hands. The aim of this study was to document clinical neuromusculoskeletal performance and somatosensory responses...

journal_title：Neural plasticity

authors： Byl NN,Nagarajan SS,Merzenich MM,Roberts T,McKenzie A

更新日期：2002-01-01 00:00:00

abstract：:One major goal in Neuroscience is the development of strategies promoting neural plasticity in the adult central nervous system, when functional recovery from brain disease and injury is limited. New evidence has underscored a pivotal role for cortical inhibitory circuitries in regulating plasticity both during develo...

journal_title：Neural plasticity

authors： Baroncelli L,Braschi C,Spolidoro M,Begenisic T,Maffei L,Sale A

更新日期：2011-01-01 00:00:00

abstract：:The plasticity of brain function, especially reorganization after stroke or sensory loss, has been investigated extensively. Based upon its special characteristics, the olfactory system allows the investigation of functional networks in patients with smell loss, as it holds the unique ability to be activated by the se...

journal_title：Neural plasticity

authors： Kollndorfer K,Kowalczyk K,Hoche E,Mueller CA,Pollak M,Trattnig S,Schöpf V

更新日期：2014-01-01 00:00:00

abstract：Objective:To compare the effects of training of jaw and finger movements with and without visual feedback on precision and accuracy. Method:Twenty healthy participants (10 men and 10 women; mean age 24.6 ± 0.8 years) performed two tasks: a jaw open-close movement and a finger lifting task with and without visual feedb...

journal_title：Neural plasticity

authors： Chen Y,Wu S,Tang Z,Zhang J,Wang L,Yu L,Wang K,Svensson P

更新日期：2019-11-18 00:00:00

abstract：:Mastoparan-7 (Mas-7), an analogue of the peptide mastoparan, which is derived from wasp venom, is a direct activator of Pertussis toxin- (PTX-) sensitive G proteins. Mas-7 produces several biological effects in different cell types; however, little is known about how Mas-7 influences mature hippocampal neurons. We exa...

journal_title：Neural plasticity

authors： Ramírez VT,Ramos-Fernández E,Inestrosa NC

更新日期：2016-01-01 00:00:00

abstract：:When activated, metabotropic glutamate receptors (mGlus) exert long-lasting changes within the glutamatergic synapses. One mechanism is a tonic effect of downstream signal transduction pathways via sustained activation of mGlu itself. Like many other G protein-coupled receptors (GPCRs), mGlu can exist in a constitutiv...

journal_title：Neural plasticity

authors： Chung G,Kim SJ

更新日期：2017-01-01 00:00:00

abstract：:Proper density and morphology of dendritic spines are important for higher brain functions such as learning and memory. However, our knowledge about molecular mechanisms that regulate thedevelopment and maintenance of dendritic spines is limited. We recently reported that cyclin-dependent kinase 5 (Cdk5) is required f...

journal_title：Neural plasticity

authors： Jin X,Sasamoto K,Nagai J,Yamazaki Y,Saito K,Goshima Y,Inoue T,Ohshima T

更新日期：2016-01-01 00:00:00

abstract：:Transcranial direct current stimulation (tDCS) can enhance the effect of conventional therapies in post-stroke neurorehabilitation. The ability to predict an individual's potential for tDCS-induced recovery may permit rehabilitation providers to make rational decisions about who will be a good candidate for tDCS thera...

journal_title：Neural plasticity

authors： Baltar A,Piscitelli D,Marques D,Shirahige L,Monte-Silva K

更新日期：2020-11-25 00:00:00

abstract：:The aim of the present study was to assess the role of action observation treatment (AOT) in the rehabilitation of upper limb motor functions in children with cerebral palsy. We carried out a two-group, parallel randomized controlled trial. Eighteen children (aged 5-11 yr) entered the study: 11 were treated children, ...

journal_title：Neural plasticity

authors： Buccino G,Molinaro A,Ambrosi C,Arisi D,Mascaro L,Pinardi C,Rossi A,Gasparotti R,Fazzi E,Galli J

更新日期：2018-07-04 00:00:00

abstract：Objective:To determine whether and how longitudinal acupuncture modulates the impaired default mode network (DMN) in chronic migraine (CM) patients without aura. Methods:Resting-state functional magnetic resonance imaging (fMRI) data from 14 CM patients treated with longitudinal pre- and postacupuncture treatment (PPA...

journal_title：Neural plasticity

authors： Zou Y,Tang W,Li X,Xu M,Li J

更新日期：2019-03-18 00:00:00

abstract：:Ciliary neurotrophic factor (CNTF) promotes survival and enhances long-distance regeneration of injured axons in parts of the adult CNS. Here we tested whether CNTF gene therapy targeting corticospinal neurons (CSN) in motor-related regions of the cerebral cortex promotes plasticity and regrowth of axons projecting in...

journal_title：Neural plasticity

authors： Hodgetts SI,Yoon JH,Fogliani A,Akinpelu EA,Baron-Heeris D,Houwers IGJ,Wheeler LPG,Majda BT,Santhakumar S,Lovett SJ,Duce E,Pollett MA,Wiseman TM,Fehily B,Harvey AR

更新日期：2018-08-06 00:00:00

abstract：:Several research studies point to the fact that sensory and cognitive reductions like cataracts, deafness, macular degeneration, or even lack of activity after job retirement, precede the onset of Alzheimer's disease. To simulate Alzheimer's disease earlier stages, which manifest in sensory cortices, we used a computa...

journal_title：Neural plasticity

authors： Aguiar-Furucho MA,Peláez FJR

更新日期：2020-10-14 00:00:00

abstract：:Noninvasive brain stimulation (NBS), such as repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS), has been used in stroke patients with motor impairment. NBS can help recovery from brain damage by modulating cortical excitability. However, the efficacy of NBS varies am...

journal_title：Neural plasticity

authors： Lee J,Lee A,Kim H,Shin M,Yun SM,Jung Y,Chang WH,Kim YH

更新日期：2019-04-07 00:00:00

abstract：:Previous studies have demonstrated that amnestic mild cognitive impairment (aMCI) has disrupted properties of large-scale cortical networks based on cortical thickness and gray matter volume. However, it is largely unknown whether the topological properties of cortical networks based on geometric measures (i.e., sulca...

journal_title：Neural plasticity

authors： Li Q,Li X,Wang X,Li Y,Li K,Yu Y,Yin C,Li S,Han Y

更新日期：2016-01-01 00:00:00

abstract：:Hyperpolarization-activated, cyclic nucleotide-gated nonselective (HCN) channels modulate both membrane potential and resistance and play a significant role in synaptic plasticity. We compared the influence of HCN channels on long-term depression (LTD) at the medial perforant path-granule cell synapse in early postnat...

journal_title：Neural plasticity

authors： Guli X,Tokay T,Rohde M,Bender RA,Köhling R,Kirschstein T

更新日期：2012-01-01 00:00:00

abstract：:Evidence suggests that inflammation and neurogenesis play an important role in major depressive disorder (MDD). Mahuang-Fuzi-Xixin decoction (MFX), as the traditional Chinese prescription, has been widely applied for asthma, migraine, and MDD in clinics. However, the effects of MFX on the potential mechanism in MDD ar...

journal_title：Neural plasticity

authors： Jing W,Song S,Sun H,Chen Y,Zhao Q,Zhang Y,Dai G,Ju W

更新日期：2019-11-11 00:00:00

abstract：:In this study, we attempted to test whether tyrosine hydroxylase (TH), the first rate-limiting enzyme of catecholamine synthesis, is confined to the perikarya of activated magnocellular vasopressinergic (VPergic) neurons or is also present in their distal axons in the pituitary posterior lobe (PL). In addition, we eva...

journal_title：Neural plasticity

authors： Abramova M,Calas A,Thibault J,Ugrumov M

更新日期：2000-01-01 00:00:00

abstract：:Transcranial Direct Current Stimulation (tDCS) is an emerging tool to improve upper limb motor functions after stroke acquired in adulthood; however, there is a paucity of reports on its efficacy for upper limb motor rehabilitation in congenital or early-acquired stroke. In this pilot study we have explored, for the f...

journal_title：Neural plasticity

authors： Inguaggiato E,Bolognini N,Fiori S,Cioni G

更新日期：2019-01-15 00:00:00

abstract：Background:Previous reviews have generally reported cognitive//behavioral improvements after cognitively oriented treatments (COTs) in persons with MCI. However, comparatively little is known about the neural mechanisms associated with such cognitive improvement. Objective:The primary aim of the current review was to ...

journal_title：Neural plasticity

authors： Miotto EC,Batista AX,Simon SS,Hampstead BM

更新日期：2018-12-02 00:00:00

abstract：:Synaptopathies are diseases with synapse defects as shared pathogenic features, encompassing neurodegenerative disorders such as Parkinson's disease (PD). In sporadic PD, the most common age-related neurodegenerative movement disorder, nigrostriatal dopaminergic deficits are responsible for the onset of motor symptoms...

journal_title：Neural plasticity

authors： Longhena F,Faustini G,Missale C,Pizzi M,Spano P,Bellucci A

更新日期：2017-01-01 00:00:00

abstract：:With the rise in the aging global population, stroke comorbidities have become a serious health threat and a tremendous economic burden on human society. Current therapeutic strategies mainly focus on protecting neurons from cytotoxic damage at the acute phase upon stroke onset, which not only is a difficult way to am...

journal_title：Neural plasticity

authors： Liu W,Wang X,O'Connor M,Wang G,Han F

更新日期：2020-01-27 00:00:00

abstract：:Objective. To explore cortical reorganization of patients recovered from Bell's palsy (BP) by task-state functional magnetic resonance imaging (fMRI) during finger and orofacial movements and provide more evidence for acupuncture clinical treatment of BP. Methods. We collected 17 BP patients with complete clinical rec...

journal_title：Neural plasticity

authors： Lee J,Yang J,Li C,Yuan A,Wu H,Wang A,Xue Q,Wang T,Wang L,Gao T

更新日期：2016-01-01 00:00:00

abstract：:Inbred mouse models are widely used to study age-related hearing loss (AHL). Many genes associated with AHL have been mapped in a variety of strains. However, little is known about gene variants that have the converse function-protective genes that confer strong resistance to hearing loss. Previously, we reported that...

journal_title：Neural plasticity

authors： Zheng QY,Kui L,Xu F,Zheng T,Li B,McCarty M,Sun Z,Zhang A,Liu L,Starlard-Davenport A,Stepanyan R,Hu BH,Lu L

更新日期：2020-06-08 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2017/6724631.]. ...

journal_title：Neural plasticity

authors： Binda P,Lunghi C

更新日期：2017-01-01 00:00:00

abstract：:Sustained activation of NLRP3 inflammasome is closely related to diabetes and stroke. However, it is unknown whether NLRP3 inflammasome plays an essential role in stroke in diabetes. We aim to investigate the effect and the potential mechanism of NLRP3 inflammasome in diabetic mice with cerebral ischemia-reperfusion i...

journal_title：Neural plasticity

authors： Hong P,Li FX,Gu RN,Fang YY,Lai LY,Wang YW,Tao T,Xu SY,You ZJ,Zhang HF

更新日期：2018-04-24 00:00:00

abstract：Background:Despite intensive rehabilitation efforts, most stroke survivors have persistent functional disability of the paretic arm and hand. These motor impairments may be due in part to maladaptive changes in structural and functional connections between brain regions. The following early stage clinical trial study p...

journal_title：Neural plasticity

authors： Borich MR,Wolf SL,Tan AQ,Palmer JA

更新日期：2018-03-12 00:00:00

abstract：:The role of attentional mechanisms in peripheral vision loss remains an outstanding question. Our study was aimed at determining the effect of genetically determined peripheral retinal dystrophy caused by Retinitis Pigmentosa (RP) on visual cortical function and tested the recruitment of attentional mechanisms using f...

journal_title：Neural plasticity

authors： Ferreira S,Pereira AC,Quendera B,Reis A,Silva ED,Castelo-Branco M

更新日期：2019-06-25 00:00:00

abstract：:Ceramides induce important intracellular signaling pathways, modulating proliferation, migration, apoptosis, and inflammation. However, the relevance of the ceramide metabolism in the reconvalescence phase after stroke is unclear. Besides its well-known property as a selective serotonin reuptake inhibitor, fluoxetine ...

journal_title：Neural plasticity

authors： Brunkhorst R,Friedlaender F,Ferreirós N,Schwalm S,Koch A,Grammatikos G,Toennes S,Foerch C,Pfeilschifter J,Pfeilschifter W

更新日期：2015-01-01 00:00:00

abstract：:Histamine H4 receptor has been confirmed to play a role in evoking peripheral pruritus. However, the ionic and intracellular signaling mechanism of activation of H4 receptor on the dorsal root ganglion (DRG) neurons is still unknown. By using cell culture and calcium imaging, we studied the underlying mechanism of act...

journal_title：Neural plasticity

authors： Jian T,Yang N,Yang Y,Zhu C,Yuan X,Yu G,Wang C,Wang Z,Shi H,Tang M,He Q,Lan L,Wu G,Tang Z

更新日期：2016-01-01 00:00:00