ZD7288 enhances long-term depression at early postnatal medial perforant path-granule cell synapses.

abstract：:Perceptual learning can be specific to a trained stimulus or optimally generalized to novel stimuli with the breadth of generalization being imperative for how we structure perceptual training programs. Adapting an established auditory interval discrimination paradigm to utilise complex signals, we trained human adult...

journal_title：Neural plasticity

authors： Brown DJ,Proulx MJ

更新日期：2013-01-01 00:00:00

abstract：:Although quantitative analysis of the sleep electroencephalogram (EEG) has uncovered important aspects of brain activity during sleep in adolescents and adults, similar findings from preschool-age children remain scarce. This study utilized our time-frequency method to examine sleep oscillations as characteristic feat...

journal_title：Neural plasticity

authors： Olbrich E,Rusterholz T,LeBourgeois MK,Achermann P

更新日期：2017-01-01 00:00:00

abstract：:Associative fear learning, in which stimulation of whiskers is paired with mild electric shock to the tail, modifies the barrel cortex, the functional representation of sensory receptors involved in the conditioning, by inducing formation of new inhibitory synapses on single-synapse spines of the cognate barrel hollow...

journal_title：Neural plasticity

authors： Jasinska M,Siucinska E,Jasek E,Litwin JA,Pyza E,Kossut M

更新日期：2016-01-01 00:00:00

abstract：:Brain cancer is a common type of childhood malignancy, and radiotherapy (RT) is a mainstay of treatment. RT is effective for tumor eradication, and survival rates are high. However, RT damages the brain and disrupts ongoing developmental processes, resulting in debilitating cognitive "late" effects that may take years...

journal_title：Neural plasticity

authors： Rodgers SP,Trevino M,Zawaski JA,Gaber MW,Leasure JL

更新日期：2013-01-01 00:00:00

abstract：:Previous studies have demonstrated that amnestic mild cognitive impairment (aMCI) has disrupted properties of large-scale cortical networks based on cortical thickness and gray matter volume. However, it is largely unknown whether the topological properties of cortical networks based on geometric measures (i.e., sulca...

journal_title：Neural plasticity

authors： Li Q,Li X,Wang X,Li Y,Li K,Yu Y,Yin C,Li S,Han Y

更新日期：2016-01-01 00:00:00

abstract：:The formation of fear memories is a powerful and highly evolutionary conserved mechanism that serves the behavioral adaptation to environmental threats. Accordingly, classical fear conditioning paradigms have been employed to investigate fundamental molecular processes of memory formation. Evidence suggests that a cir...

journal_title：Neural plasticity

authors： Albrecht A,Stork O

更新日期：2017-01-01 00:00:00

abstract：:Cerebral palsy (CP) has long been investigated to be associated with a range of motor and cognitive dysfunction. As the two most common CP subtypes, spastic cerebral palsy (SCP) and dyskinetic cerebral palsy (DCP) may share common and distinct elements in their pathophysiology. However, the common and distinct dysfunc...

journal_title：Neural plasticity

authors： Qin Y,Li Y,Sun B,He H,Peng R,Zhang T,Li J,Luo C,Sun C,Yao D

更新日期：2018-08-15 00:00:00

abstract：:The habituation/cross-habituation test (HaXha) is a spontaneous odor discrimination task that has been used for many decades to evaluate olfactory function in animals. Animals are presented repeatedly with the same odorant after which a new odorant is introduced. The time the animal explores the odor object is measure...

journal_title：Neural plasticity

authors： Coronas-Samano G,Ivanova AV,Verhagen JV

更新日期：2016-01-01 00:00:00

abstract：:Cholinergic mechanism is involved in motor behavior. In songbirds, the robust nucleus of the arcopallium (RA) is a song premotor nucleus in the pallium and receives cholinergic inputs from the basal forebrain. The activity of projection neurons in RA determines song motor behavior. Although many evidences suggest that...

journal_title：Neural plasticity

authors： Meng W,Wang SH,Li DF

更新日期：2016-01-01 00:00:00

abstract：:Ionizing radiation is omnipresent. We are continuously exposed to natural (e.g., radon and cosmic) and man-made radiation sources, including those from industry but especially from the medical sector. The increasing use of medical radiation modalities, in particular those employing low-dose radiation such as CT scans,...

journal_title：Neural plasticity

authors： Verreet T,Verslegers M,Quintens R,Baatout S,Benotmane MA

更新日期：2016-01-01 00:00:00

abstract：:Mirror visual feedback (MVF) therapy has been applied to improve upper limb function in stroke. When combined with motor training, MVF improves the performance of the trained and untrained hand by enhancing the excitability of both primary motor cortices (M1s). Bradykinesia is a typical feature of Parkinson's disease ...

journal_title：Neural plasticity

authors： Bonassi G,Pelosin E,Ogliastro C,Cerulli C,Abbruzzese G,Avanzino L

更新日期：2016-01-01 00:00:00

abstract：:Increasing research has evidenced that our brain retains a capacity to change in response to experience until late adulthood. This implies that cognitive training can possibly ameliorate age-associated cognitive decline by inducing training-specific neural plastic changes at both neural and behavioral levels. This lon...

journal_title：Neural plasticity

authors： Leung NT,Tam HM,Chu LW,Kwok TC,Chan F,Lam LC,Woo J,Lee TM

更新日期：2015-01-01 00:00:00

abstract：:Although many studies have investigated the functions of histidine triad nucleotide-binding protein 1 (HINT1), its roles in neurobiological processes remain to be fully elucidated. As a member of the histidine triad (HIT) enzyme superfamily, HINT1 is distributed in almost every organ and has both enzymatic and nonenzy...

journal_title：Neural plasticity

authors： Liu P,Liu Z,Wang J,Ma X,Dang Y

更新日期：2017-01-01 00:00:00

abstract：:Neurophysiological and neuroimaging data suggest that the brains of not only children but also adults are reorganized based on sensory inputs and behaviors. Plastic changes in the brain are generally beneficial; however, maladaptive cortical reorganization in the auditory cortex may lead to hearing disorders such as t...

journal_title：Neural plasticity

authors： Okamoto H

更新日期：2018-05-20 00:00:00

abstract：:Studies on visually deprived individuals provide one of the most striking demonstrations that the brain is highly plastic and is able to rewire as a function of the sensory input it receives from the environment. In the current paper, we focus on spatial abilities that are typically related to the dorsal visual pathwa...

journal_title：Neural plasticity

authors： Dormal G,Lepore F,Collignon O

更新日期：2012-01-01 00:00:00

abstract：:Functional and effective connectivity of cortical areas are essential for normal brain function under different behavioral states. Appropriate cortical activity during sleep and wakefulness is ensured by the balanced activity of excitatory and inhibitory circuits. Ultimately, fast, millisecond cortical rhythmic oscill...

journal_title：Neural plasticity

authors： Vanvinckenroye A,Vandewalle G,Phillips C,Chellappa SL

更新日期：2016-01-01 00:00:00

abstract：Background:Sudden sensorineural hearing loss (SSNHL) is an otologic emergency and could lead to social difficulties and mental disorders in some patients. Although many studies have analyzed altered brain function in populations with hearing loss, little information is available about patients with idiopathic SSNHL. Th...

journal_title：Neural plasticity

authors： Chen J,Hu B,Qin P,Gao W,Liu C,Zi D,Ding X,Yu Y,Cui G,Lu L

更新日期：2020-09-22 00:00:00

abstract：:Ample evidence suggests that estrogens have strong influences on the occurrence of stress-related mood disorders, but the underlying mechanisms remain poorly understood. Through multiple approaches, we demonstrate that the G protein-coupled estrogen receptor (GPER) is widely distributed along the HPA axis and in brain...

journal_title：Neural plasticity

authors： Zheng Y,Wu M,Gao T,Meng L,Ding X,Meng Y,Jiao Y,Luo P,He Z,Sun T,Zhang G,Shi X,Rong W

更新日期：2020-08-28 00:00:00

abstract：Background and Purpose:Cancer-related fatigue (CRF) is widely recognized as one of the most common symptoms and side effects of cancer and/or its treatment. However, neuropathological mechanisms contributing to CRF are largely unknown, and the lack of knowledge makes CRF difficult to treat. Recent research has shown di...

journal_title：Neural plasticity

authors： Jiang C,Yang Q,Chen T,Siemionow V,Ranganathan VK,Yan AF,Yue GH

更新日期：2019-06-26 00:00:00

abstract：:We do not all grow older in the same way. Some individuals have a cognitive decline earlier and faster than others who are older in years but cerebrally younger. This is particularly easy to verify in people who have maintained regular physical activity and healthy and cognitively stimulating lifestyle and even in the...

journal_title：Neural plasticity

authors： Mandolesi L,Gelfo F,Serra L,Montuori S,Polverino A,Curcio G,Sorrentino G

更新日期：2017-01-01 00:00:00

abstract：:Matricellular proteins are secreted, nonstructural proteins that regulate the extracellular matrix (ECM) and interactions between cells through modulation of growth factor signaling, cell adhesion, migration, and proliferation. Despite being well described in the context of nonneuronal tissues, recent studies have rev...

journal_title：Neural plasticity

authors： Jones EV,Bouvier DS

更新日期：2014-01-01 00:00:00

abstract：Background:Previous reviews have generally reported cognitive//behavioral improvements after cognitively oriented treatments (COTs) in persons with MCI. However, comparatively little is known about the neural mechanisms associated with such cognitive improvement. Objective:The primary aim of the current review was to ...

journal_title：Neural plasticity

authors： Miotto EC,Batista AX,Simon SS,Hampstead BM

更新日期：2018-12-02 00:00:00

abstract：:Adverse early life experiences can negatively affect behaviors later in life. Maternal separation (MS) has been extensively investigated in animal models in the adult phase of MS. The study aimed to explore the mechanism by which MS negatively affects C57BL/6N mice, especially the effects caused by MS in the early pha...

journal_title：Neural plasticity

authors： Bian Y,Yang L,Wang Z,Wang Q,Zeng L,Xu G

更新日期：2015-01-01 00:00:00

abstract：:Glaucoma is an irreversible blinding eye disease which produces progressive retinal ganglion cell (RGC) loss. Intraocular pressure (IOP) is currently the only modifiable risk factor, and lowering IOP results in reduced risk of progression of the disorder. The endocannabinoid system (ECS) has attracted considerable att...

journal_title：Neural plasticity

authors： Cairns EA,Baldridge WH,Kelly ME

更新日期：2016-01-01 00:00:00

abstract：:When activated, metabotropic glutamate receptors (mGlus) exert long-lasting changes within the glutamatergic synapses. One mechanism is a tonic effect of downstream signal transduction pathways via sustained activation of mGlu itself. Like many other G protein-coupled receptors (GPCRs), mGlu can exist in a constitutiv...

journal_title：Neural plasticity

authors： Chung G,Kim SJ

更新日期：2017-01-01 00:00:00

abstract：:Elevated brain activation, or hyperexcitability, induces cognitive impairment and confers an increased risk of Alzheimer's disease (AD). Blocking the overexcitation of the neural network may be a promising new strategy to prevent, halt, and even reverse this condition. Physical exercise has been shown to be an effecti...

journal_title：Neural plasticity

authors： Tan YX,Liu GC,Chen HL,Lu MN,Chen B,Hu T,Zhang L,Mao R,Li S,Mei R,Wang XY,Xiyang YB

更新日期：2020-03-18 00:00:00

abstract：:Occurrence of language impairment in mesial temporal lobe epilepsy (mTLE) patients is common and left mTLE patients always exhibit a primary problem with access to names. To explore different neuropsychological profiles between left and right mTLE patients, the study investigated both structural and effective function...

journal_title：Neural plasticity

authors： Fan X,Yan H,Shan Y,Shang K,Wang X,Wang P,Shan Y,Lu J,Zhao G

更新日期：2016-01-01 00:00:00

abstract：:With the rise in the aging global population, stroke comorbidities have become a serious health threat and a tremendous economic burden on human society. Current therapeutic strategies mainly focus on protecting neurons from cytotoxic damage at the acute phase upon stroke onset, which not only is a difficult way to am...

journal_title：Neural plasticity

authors： Liu W,Wang X,O'Connor M,Wang G,Han F

更新日期：2020-01-27 00:00:00

abstract：:Perinatal stroke is a leading cause of congenital hemiparesis and neurocognitive deficits in children. Dysfunctions in the large-scale resting-state functional networks may underlie cognitive and behavioral disability in these children. We studied resting-state functional connectivity in patients with perinatal stroke...

journal_title：Neural plasticity

authors： Ilves N,Ilves P,Laugesaar R,Juurmaa J,Männamaa M,Lõo S,Loorits D,Tomberg T,Kolk A,Talvik I,Talvik T

更新日期：2016-01-01 00:00:00

abstract：:Magnetic resonance imaging (MRI) of the human brain has provided converging evidence that visual deprivation induces regional changes in white matter (WM) microstructure. It remains unclear how these changes modify network connections between brain regions. Here we used diffusion-weighted MRI to relate differences in ...

journal_title：Neural plasticity

authors： Reislev NL,Dyrby TB,Siebner HR,Kupers R,Ptito M

更新日期：2016-01-01 00:00:00