Corrigendum: Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis.

abstract：:It has been contended that any observed difference of the corpus callosum (CC) size between men and women is not sex-related but brain-size-related. A recent report, however, showed that the midsagittal CC area was significantly larger in women in 37 brain-size-matched pairs of normal young adults. Since this constitu...

journal_title：Scientific reports

authors： Shiino A,Chen YW,Tanigaki K,Yamada A,Vigers P,Watanabe T,Tooyama I,Akiguchi I

更新日期：2017-01-03 00:00:00

abstract：:Microbial metabolites, produced in the intestine, have significant effects on inflammatory diseases throughout the body. Short-chain fatty acids (SCFAs) have protective effects on experimental autoimmune encephalitis (EAE) responses but the detailed roles of SCFAs and their receptors in regulating autoimmune CNS infla...

journal_title：Scientific reports

authors： Park J,Wang Q,Wu Q,Mao-Draayer Y,Kim CH

更新日期：2019-06-20 00:00:00

abstract：:Using a free boundary approach based on an analogy with ice melting models, we propose a deterministic PDE framework to describe the dynamics of fitness distributions in the presence of beneficial mutations with non-epistatic effects on fitness. Contrarily to most approaches based on deterministic models, our framewor...

journal_title：Scientific reports

authors： Roques L,Garnier J,Martin G

更新日期：2017-12-19 00:00:00

abstract：:Recent successes in malaria control have been largely attributable to the deployment of insecticide-based vector control tools such as bed nets and indoor residual spraying. Pyrethroid-treated bed nets are acutely neurotoxic to mosquitoes, inducing symptoms such as loss of coordination, paralysis, and violent spasms. ...

journal_title：Scientific reports

authors： Isaacs AT,Lynd A,Donnelly MJ

更新日期：2017-04-25 00:00:00

abstract：:Marine biofouling remains an unsolved problem with a serious economic impact on several marine associated industries and constitutes a major vector for the spread of non-indigenous species (NIS). The implementation of biofouling monitoring programs allows for better fouling management and also for the early identifica...

journal_title：Scientific reports

authors： Azevedo J,Antunes JT,Machado AM,Vasconcelos V,Leão PN,Froufe E

更新日期：2020-08-10 00:00:00

abstract：:During chronic cerebral hypoperfusion (CCH), the cerebral blood flow gradually decreases, leading to cognitive impairments and neurodegenerative disorders, such as vascular dementia. The reduced oxygenation, energy supply induced metabolic changes, and insufficient neuroplasticity could be reflected in the synaptic pr...

journal_title：Scientific reports

authors： Tukacs V,Mittli D,Györffy BA,Hunyady-Gulyás É,Hlatky D,Tóth V,Ravasz L,Medzihradszky FK,Nyitrai G,Czurkó A,Juhász G,Kardos J,Kékesi KA

更新日期：2020-09-29 00:00:00

abstract：:Inhibition of DYRK1A kinase, produced by chromosome 21 and consequently overproduced in trisomy 21 subjects, has been suggested as a therapeutic approach to treating the cognitive deficiencies observed in Down syndrome (DS). We now report the synthesis and potent DYRK1A inhibitory activities of fluoro derivatives of 3...

journal_title：Scientific reports

authors： Neumann F,Gourdain S,Albac C,Dekker AD,Bui LC,Dairou J,Schmitz-Afonso I,Hue N,Rodrigues-Lima F,Delabar JM,Potier MC,Le Caër JP,Touboul D,Delatour B,Cariou K,Dodd RH

更新日期：2018-02-12 00:00:00

abstract：:Traditional risk assessment and source apportionment of sediments based on bulk polycyclic aromatic hydrocarbons (PAHs) can introduce biases due to unknown aging effects in various sediments. We used a mild solvent (hydroxypropyl-β-cyclodextrin) to extract the bioavailable fraction of PAHs (a-PAHs) from sediment sampl...

journal_title：Scientific reports

authors： Yang X,Yu L,Chen Z,Xu M

更新日期：2016-03-15 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Farmery JHR,Smith ML,NIHR BioResource - Rare Diseases.,Lynch AG

更新日期：2018-09-03 00:00:00

abstract：:Self-healing is a capacity observed in most biological systems in which the healing processes are autonomously triggered after the damage. Inspired by this natural behavior, researchers believed that a synthetic material possessing similar self-recovery capability could also be developed. Albeit various intrinsic self...

journal_title：Scientific reports

authors： Chen J,Dong Q,Ma X,Fan TH,Lei Y

更新日期：2016-08-22 00:00:00

abstract：:There is a lack of evidence that either conventional observational rating scale or biomechanical system is a better tremor assessment tool. This work focuses on comparing a biomechanical system and the Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale in terms of test-retest ...

journal_title：Scientific reports

authors： Chan PY,Mohd Ripin Z,Abdul Halim S,Kamarudin MI,Ng KS,Eow GB,Tan K,Cheah CF,Then L,Soong N,Hor JY,Yahya AS,Arifin WN,Tharakan J,Mustapha M

更新日期：2019-05-31 00:00:00

abstract：:Chemokines promote leukocyte recruitment during inflammation. The oxidative burst is an important effector mechanism, this leads to the generation of reactive nitrogen species (RNS), including peroxynitrite (ONOO). The current study was performed to determine the potential for nitration to alter the chemical and biolo...

journal_title：Scientific reports

authors： Barker CE,Thompson S,O'Boyle G,Lortat-Jacob H,Sheerin NS,Ali S,Kirby JA

更新日期：2017-03-14 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Cabrera-Cruz SA,Smolinsky JA,Buler JJ

更新日期：2018-03-14 00:00:00

abstract：:Hot-iron disbudding, a routine procedure that prevents horn bud growth through cauterization, is painful for calves. The resulting burns remain sensitive to touch for weeks, but it is unknown whether calves experience ongoing, non-evoked pain. We evaluated conditioned place preference for analgesia in 44 calves disbud...

journal_title：Scientific reports

authors： Adcock SJJ,Tucker CB

更新日期：2020-03-02 00:00:00

abstract：:Brain imaging genetics intends to uncover associations between genetic markers and neuroimaging quantitative traits. Sparse canonical correlation analysis (SCCA) can discover bi-multivariate associations and select relevant features, and is becoming popular in imaging genetic studies. The L1-norm function is not only ...

journal_title：Scientific reports

authors： Du L,Liu K,Yao X,Yan J,Risacher SL,Han J,Guo L,Saykin AJ,Shen L,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2017-10-25 00:00:00

abstract：:Worldwide variation in human stature and limb proportions is widely accepted to reflect thermal adaptation, but the contribution of population history to this variation is unknown. Furthermore, stature and relative lower limb length (LLL) show substantial plastic responses to environmental stressors, e.g., nutrition, ...

journal_title：Scientific reports

authors： Pomeroy E,Stock JT,Wells JCK

更新日期：2021-01-11 00:00:00

abstract：:The global problem of unowned domestic cats, driven by their phenomenal reproductive success, carries significant economic, animal welfare and biodiversity costs. Desexing owned cats prior to puberty prevents unwanted litters that contribute to unowned cat populations. The prevalence and predictors of desexing, and th...

journal_title：Scientific reports

authors： Mazeau L,Wylie C,Boland L,Beatty JA

更新日期：2021-01-18 00:00:00

abstract：:Long noncoding RNAs (lncRNAs) represent a vast unexplored genetic space that may hold missing drivers of tumourigenesis, but few such "driver lncRNAs" are known. Until now, they have been discovered through changes in expression, leading to problems in distinguishing between causative roles and passenger effects. We h...

journal_title：Scientific reports

authors： Lanzós A,Carlevaro-Fita J,Mularoni L,Reverter F,Palumbo E,Guigó R,Johnson R

更新日期：2017-01-27 00:00:00

abstract：:Plasma free amino acid (PFAA) profile is highlighted in its association with visceral obesity and hyperinsulinemia, and future diabetes. Indeed PFAA profiling potentially can evaluate individuals' future risks of developing lifestyle-related diseases, in addition to diabetes. However, few studies have been performed e...

journal_title：Scientific reports

authors： Yamakado M,Nagao K,Imaizumi A,Tani M,Toda A,Tanaka T,Jinzu H,Miyano H,Yamamoto H,Daimon T,Horimoto K,Ishizaka Y

更新日期：2015-07-09 00:00:00

abstract：:How exponentially growing cells maintain size homeostasis is an important fundamental problem. Recent single-cell studies in prokaryotes have uncovered the adder principle, where cells add a fixed size (volume) from birth to division, irrespective of their size at birth. To mechanistically explain the adder principle,...

journal_title：Scientific reports

authors： Ghusinga KR,Vargas-Garcia CA,Singh A

更新日期：2016-07-26 00:00:00

abstract：:Knowledge of brain correlates of postural control is limited by the technical difficulties in performing controlled experiments with currently available neuroimaging methods. Here we present a system that allows the measurement of anticipatory postural adjustment of human legs to be synchronized with the acquisition o...

journal_title：Scientific reports

authors： de Lima-Pardini AC,de Azevedo Neto RM,Coelho DB,Boffino CC,Shergill SS,de Oliveira Souza C,Brant R,Barbosa ER,Cardoso EF,Teixeira LA,Cohen RG,Horak FB,Amaro E Jr

更新日期：2017-02-23 00:00:00

abstract：:Although the association between social support and postpartum depression has been previously investigated, its causal relationship remains unclear. Therefore, we examined prospectively whether social support during pregnancy affected postpartum depression. Social support and depressive symptoms were assessed by Japan...

journal_title：Scientific reports

authors： Morikawa M,Okada T,Ando M,Aleksic B,Kunimoto S,Nakamura Y,Kubota C,Uno Y,Tamaji A,Hayakawa N,Furumura K,Shiino T,Morita T,Ishikawa N,Ohoka H,Usui H,Banno N,Murase S,Goto S,Kanai A,Masuda T,Ozaki N

更新日期：2015-05-29 00:00:00

abstract：:Electrochemical nanosensors based on nanoporous gold leaf (NPGL) and molecularly imprinted polymer (MIP) are developed for pharmaceutical analysis by using metronidazole (MNZ) as a model analyte. NPGL, serving as the loading platform for MIP immobilization, possesses large accessible surface area with superb electric ...

journal_title：Scientific reports

authors： Li Y,Liu Y,Liu J,Liu J,Tang H,Cao C,Zhao D,Ding Y

更新日期：2015-01-09 00:00:00

abstract：:Excessive tillage and soil compaction threaten the sustainable farmlands in the Huang-Huai-Hai Plains of China. Our study explores tillage practices to improve soil and root ecology and promote productivity in the winter wheat fields. We tested the impact of plowing, rotary, strip rotary tillage and strip rotary tilla...

journal_title：Scientific reports

authors： He J,Shi Y,Zhao J,Yu Z

更新日期：2019-08-12 00:00:00

abstract：:Peripheral neural signals have the potential to provide the necessary motor, sensory or autonomic information for robust control in many neuroprosthetic and neuromodulation applications. However, developing methods to recover information encoded in these signals is a significant challenge. We introduce the idea of usi...

journal_title：Scientific reports

authors： Koh RGL,Nachman AI,Zariffa J

更新日期：2019-07-31 00:00:00

abstract：:Two types of periodic and transient motions of large woodpeckers are considered. A drumming woodpecker may be modeled as a harmonic oscillator with a periodic forcing function. The transient behavior that occurs after the forcing is turned off suggests that the double knocks of Campephilus woodpeckers may be modeled i...

journal_title：Scientific reports

authors： Collins MD

更新日期：2017-10-02 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease for which the pathophysiological mechanisms of motor neuron loss are not precisely clarified. Environmental and epigenetic mechanisms such as microRNAs (miRNAs) could have a role in disease progression. We studied the expression pattern of miRNAs in AL...

journal_title：Scientific reports

authors： De Luna N,Turon-Sans J,Cortes-Vicente E,Carrasco-Rozas A,Illán-Gala I,Dols-Icardo O,Clarimón J,Lleó A,Gallardo E,Illa I,Rojas-García R

更新日期：2020-03-09 00:00:00

abstract：:Surgery and anesthesia induce inflammatory changes in the central nervous system, which ultimately lead to neuronal damage concomitant with an increase in the level of neurodegeneration markers. Despite some experimental data showing prolonged activation of the immune system post-surgery, no study has determined the e...

journal_title：Scientific reports

authors： DiMeglio M,Furey W,Hajj J,Lindekens J,Patel S,Acker M,Bavaria J,Szeto WY,Atluri P,Haber M,Diaz-Arrastia R,Laudanski K

更新日期：2019-05-09 00:00:00

abstract：:Among atrial fibrillation (AF) patients, Danish nationwide registries (2011-2015) were used to examine temporal trends of initiation patterns of oral anticoagulation (OAC) treatment according to age. Overall, 43,299 AF patients initiating vitamin K antagonists (VKA) (42%), dabigatran (29%), rivaroxaban (13%), or apixa...

journal_title：Scientific reports

authors： Staerk L,Fosbøl EL,Gadsbøll K,Sindet-Pedersen C,Pallisgaard JL,Lamberts M,Lip GY,Torp-Pedersen C,Gislason GH,Olesen JB

更新日期：2016-08-11 00:00:00

abstract：:Pinellia (Pinellia ternata (Thunb.) Breit.), as important medicinal plant, has been used to treat various ailments for a long time. The sixteen ploid plant (2n = 16 * 13 = 208) Pinellia T2Plus line was obtained from an octoploid (2n = 8 * 13 = 104) T2 line by chromosome-doubling technique. Compared with T2 line, the c...

journal_title：Scientific reports

authors： Lu J,Liu JN,Sarsaiya S,Duns GJ,Han J,Jin L,Chen J

更新日期：2020-03-12 00:00:00