Population history and ecology, in addition to climate, influence human stature and body proportions.

abstract：:In using nanostructures to design solar thermal absorbers, computational methods, such as rigorous coupled-wave analysis and the finite-difference time-domain method, are often employed to simulate light-structure interactions in the solar spectrum. However, those methods require heavy computational resources and CPU ...

journal_title：Scientific reports

authors： Seo J,Jung PH,Kim M,Yang S,Lee I,Lee J,Lee H,Lee BJ

更新日期：2019-10-21 00:00:00

abstract：:The renin-angiotensin system is known to regulate blood pressure as well as water- and electrolyte balance. An activated RAS is involved in the development of hypertension and hypertension-related organ damage. Thus, inhibitors of the RAS are protective and markedly increasing the life span of patients. In contrast, r...

journal_title：Scientific reports

authors： Wanka H,Lutze P,Staar D,Bracke K,Golchert J,Peters J

更新日期：2020-11-12 00:00:00

abstract：:Thirty-nine UK adapted wheat cultivars dating from between 1790 and 2012 were grown in replicated randomised field trials for three years, milled, and white flour analysed for the contents of dietary fibre components (arabinoxylan and β-glucan) and polar metabolites (sugars, amino acids, organic acids, choline and bet...

journal_title：Scientific reports

authors： Lovegrove A,Pellny TK,Hassall KL,Plummer A,Wood A,Bellisai A,Przewieslik-Allen A,Burridge AJ,Ward JL,Shewry PR

更新日期：2020-04-03 00:00:00

abstract：:Diagnosis and treatment of vocal fold lesions has been a long-evolving science for the otolaryngologist. Contemporary practice requires biopsy of a glottal lesion in the operating room under general anesthesia for diagnosis. Current in-office technology is limited to visualizing the surface of the vocal folds with fib...

journal_title：Scientific reports

authors： Coughlan CA,Chou LD,Jing JC,Chen JJ,Rangarajan S,Chang TH,Sharma GK,Cho K,Lee D,Goddard JA,Chen Z,Wong BJ

更新日期：2016-03-10 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is an increasing health problem worldwide, with genetic, epigenetic, and environmental components. Here, we describe the first example of NAFLD caused by genetic disruption of a mammalian potassium channel subunit. Mice with germline deletion of the KCNE2 potassium channel β su...

journal_title：Scientific reports

authors： Lee SM,Nguyen D,Anand M,Kant R,Köhncke C,Lisewski U,Roepke TK,Hu Z,Abbott GW

更新日期：2016-03-17 00:00:00

abstract：:Looking for single molecule electronic devices, we have investigated the charge transport properties of individual tetra-phenylporphyrin molecules on different substrates by ultrahigh-vacuum scanning tunneling microscopy and spectroscopy and by first-principles calculations. The tetra-phenylporphyrins with a Co atom (...

journal_title：Scientific reports

authors： Zoldan VC,Faccio R,Pasa AA

更新日期：2015-02-10 00:00:00

abstract：:The adsorption of glycine, glutamic acid, histidine and phenylalanine on single-layer graphdiyne/graphene is investigated by ab initio calculations. The results show that for each amino acid molecule, the adsorption energy on graphdiyne is larger than the adsorption energy on graphene and dispersion interactions predo...

journal_title：Scientific reports

authors： Chen X,Gao P,Guo L,Zhang S

更新日期：2015-11-16 00:00:00

abstract：:A new energy dispersive X-ray absorption spectroscopy (EDXAS) method is presented for simultaneous wide-field imaging and transmission X-ray absorption spectroscopy (XAS) to enable rapid imaging and speciation of elements. Based on spectral K-Edge Subtraction imaging (sKES), a bent Laue imaging system diffracting in t...

journal_title：Scientific reports

authors： Qi P,Samadi N,Martinson M,Ponomarenko O,Bassey B,Gomez A,George GN,Pickering IJ,Chapman LD

更新日期：2019-11-27 00:00:00

abstract：:Conventional disease animal models have limitations on the conformity to the actual clinical situation. Disease-syndrome combination (DS) modeling may provide a more efficient strategy for biomedicine research. Disease model and DS model of renal fibrosis in chronic kidney disease were established by ligating the left...

journal_title：Scientific reports

authors： Li S,Xu P,Han L,Mao W,Wang Y,Luo G,Yang N

更新日期：2017-08-18 00:00:00

abstract：:Production of lactic acid from glycerol is a cascade catalytic procedure using multifunctional catalysts combined with oxidative and acidic catalytic sites. Therefore, a series of silver-exchanged phosphomolybdic acid catalysts (AgxH3-xPMo12O40, x = 1 ~ 3, abbreviated as AgxPMo) was designed and applied in glycerol ox...

journal_title：Scientific reports

authors： Tao M,Dan Zhang,Guan H,Huang G,Wang X

更新日期：2016-07-19 00:00:00

abstract：:The spontaneous activity of sinoatrial node (SAN) pacemaker cells is generated by a functional interplay between the activity of ionic currents of the plasma membrane and intracellular Ca2+ dynamics. The molecular correlate of a dihydropyridine (DHP)-sensitive sustained inward Na+ current (I st), a key player in SAN a...

journal_title：Scientific reports

authors： Toyoda F,Mesirca P,Dubel S,Ding WG,Striessnig J,Mangoni ME,Matsuura H

更新日期：2017-08-11 00:00:00

abstract：:Episodic ataxia is an autosomal dominant ion channel disorder characterized by episodes of imbalance and incoordination. The disease is genetically heterogeneous and is classified as episodic ataxia type 2 (EA2) when it is caused by a mutation in the CACNA1A gene, encoding the α1A subunit of the P/Q-type voltage-gated...

journal_title：Scientific reports

authors： Sintas C,Carreño O,Fernàndez-Castillo N,Corominas R,Vila-Pueyo M,Toma C,Cuenca-León E,Barroeta I,Roig C,Volpini V,Macaya A,Cormand B

更新日期：2017-05-31 00:00:00

abstract：:Recent studies demonstrate the functions of long non-coding RNAs (lncRNAs) in mediating gene expression at the transcriptional or translational level. Our previous study identified a Sirt1 antisense (AS) lncRNA transcribed from the Sirt1 AS strand. However, its role and regulatory mechanism is still unknown in myogene...

journal_title：Scientific reports

authors： Wang GQ,Wang Y,Xiong Y,Chen XC,Ma ML,Cai R,Gao Y,Sun YM,Yang GS,Pang WJ

更新日期：2016-02-23 00:00:00

abstract：:Ballooning degeneration (BD) of hepatocytes is a distinguishing histological feature associated with the progression of nonalcoholic fatty liver disease (NAFLD). Under the assumption that NAFLD severity is associated with metabolic-stress we explored the hypothesis that heat shock 27 kDa protein 1 (HSP27), a protein c...

journal_title：Scientific reports

authors： Sookoian S,Castaño GO,Scian R,San Martino J,Pirola CJ

更新日期：2016-03-03 00:00:00

abstract：:Three H10 subtype avian influenza viruses were isolated from domestic ducks in China, designated as SH602/H10N8, FJ1761/H10N3 and SX3180/H10N7, with an intravenous pathogenicity index (IVPI) of 0.39, 1.60, and 1.27, respectively. These H10 viruses showed a complex pathology pattern in different species, although full ...

journal_title：Scientific reports

authors： Zhang M,Zhang X,Xu K,Teng Q,Liu Q,Li X,Yang J,Xu J,Chen H,Zhang X,Li Z

更新日期：2016-09-28 00:00:00

abstract：:In a standard semiconductor laser, electrons and holes recombine via stimulated emission to emit coherent light, in a process that is far from thermal equilibrium. Exciton-polariton condensates-sharing the same basic device structure as a semiconductor laser, consisting of quantum wells coupled to a microcavity-have b...

journal_title：Scientific reports

authors： Horikiri T,Yamaguchi M,Kamide K,Matsuo Y,Byrnes T,Ishida N,Löffler A,Höfling S,Shikano Y,Ogawa T,Forchel A,Yamamoto Y

更新日期：2016-05-19 00:00:00

abstract：:Chronic lymphocytic leukaemia (CLL) is characterised by a heterogeneous clinical course. Such heterogeneity is associated with a number of markers, including TP53 gene inactivation. While TP53 gene alterations determine resistance to chemotherapy, it is not clear whether they can influence early disease progression. T...

journal_title：Scientific reports

authors： Monti P,Lionetti M,De Luca G,Menichini P,Recchia AG,Matis S,Colombo M,Fabris S,Speciale A,Barbieri M,Gentile M,Zupo S,Dono M,Ibatici A,Neri A,Ferrarini M,Fais F,Fronza G,Cutrona G,Morabito F

更新日期：2020-10-28 00:00:00

abstract：:Recently, electromagnetic (EM) waves carrying orbital angular momentum (OAM) has received considerable attention in increasingly many different realms, such as communication systems, super-resolution imaging, optical communications and quantum state manipulation. In this paper, two different kinds of two dimensional (...

journal_title：Scientific reports

authors： Oraizi H,Emamian H

更新日期：2020-04-30 00:00:00

abstract：:Pituitary adenylate cyclase activating polypeptide (PACAP) is a regulatory and cytoprotective neuropeptide, its deficiency implies accelerated aging in mice. It is present in the auditory system having antiapoptotic effects. Expression of Ca2+-binding proteins and its PAC1 receptor differs in the inner ear of PACAP-de...

journal_title：Scientific reports

authors： Fulop DB,Humli V,Szepesy J,Ott V,Reglodi D,Gaszner B,Nemeth A,Szirmai A,Tamas L,Hashimoto H,Zelles T,Tamas A

更新日期：2019-10-10 00:00:00

abstract：:Despite increasing work detailing the presence of foraging specializations across a range of taxa, limited attention so far has been given to the role of spatiotemporal variation in food predictability in shaping individual resource selection. Here, we studied the exploitation of human-provided carrion resources diffe...

journal_title：Scientific reports

authors： van Overveld T,García-Alfonso M,Dingemanse NJ,Bouten W,Gangoso L,de la Riva M,Serrano D,Donázar JA

更新日期：2018-10-11 00:00:00

abstract：:Cardiorenal syndrome, de novo renal pathology arising secondary to cardiac insufficiency, is clinically recognised but poorly characterised. This study establishes and characterises a valid model representative of Type 2 cardiorenal syndrome. Extensive permanent left ventricular infarction, induced by ligation of the ...

journal_title：Scientific reports

authors： Harrison JC,Smart SDG,Besley EMH,Kelly JR,Read MI,Yao Y,Sammut IA

更新日期：2020-01-27 00:00:00

abstract：:Myeloid-derived suppressor cells (MDSCs) are immune cells that exert immunosuppression within the tumor, protecting cancer cells from the host's immune system and/or exogenous immunotherapies. While current research has been mostly focused in countering MDSC-driven immunosuppression, little is known about the mechanis...

journal_title：Scientific reports

authors： Duarte-Sanmiguel S,Shukla V,Benner B,Moore J,Lemmerman L,Lawrence W,Panic A,Wang S,Idzkowski N,Guio-Vega G,Higuita-Castro N,Ghadiali S,Carson WE,Gallego-Perez D

更新日期：2020-01-27 00:00:00

abstract：:The liver has a variety of functions for maintaining homeostasis, and hepatocytes play a major role. In contrast with the high regenerative capacity of mature hepatocytes (MHs) in vivo, they have not been successfully expanded ex vivo. Here we demonstrate that CD44-positive cells sorted from small hepatocyte (SH) colo...

journal_title：Scientific reports

authors： Ishii M,Kino J,Ichinohe N,Tanimizu N,Ninomiya T,Suzuki H,Mizuguchi T,Hirata K,Mitaka T

更新日期：2017-04-11 00:00:00

abstract：:Nitric oxide (NO) produced by endothelial cells in response to cytokines displays anti-inflammatory activity by preventing the adherence, migration and activation of neutrophils. The molecular mechanism by which NO operates at the blood-endothelium interface to exert anti-inflammatory properties is largely unknown. He...

journal_title：Scientific reports

authors： Lai TS,Lindberg RA,Zhou HL,Haroon ZA,Dewhirst MW,Hausladen A,Juang YL,Stamler JS,Greenberg CS

更新日期：2017-11-23 00:00:00

abstract：:The ability to respond appropriately to challenges is an important contributor to fitness. Variation in the regulation of glucocorticoid hormones, which mediate the phenotypic response to challenges, can therefore influence the ability to persist in a given environment. We compared stress responsiveness in four popula...

journal_title：Scientific reports

authors： Zimmer C,Taff CC,Ardia DR,Rose AP,Aborn DA,Johnson LS,Vitousek MN

更新日期：2020-08-13 00:00:00

abstract：:Due to distinct biological behavior of mucinous adenocarcinoma (MAC) and signet ring cell cancer (SRC), the efficacy of radiotherapy on long-term outcome for rectal cancer (RC) patients with mucinous tumors is still unclear. Here, we identified 1808 RC patients with MAC/SRC from Surveillance, Epidemiology, and End-Res...

journal_title：Scientific reports

authors： Guan X,Jia S,Chen W,Jiang Z,Liu Z,Chen Y,Wang G,Wang X

更新日期：2017-03-08 00:00:00

abstract：:This study demonstrated the usefulness of radiomic features based on the Hessian index of differential topology for the prediction of prognosis prior to treatment in head-and-neck (HN) cancer patients. The Hessian index, which can indicate tumor heterogeneity with convex, concave, and other points (saddle points), was...

journal_title：Scientific reports

authors： Le QC,Arimura H,Ninomiya K,Kabata Y

更新日期：2020-12-04 00:00:00

abstract：:In this study, we developed a novel poly (lactic-co-glycolic acid)-dextran (PLD)-based nanodelivery system to enhance the anticancer potential of cisplatin (CDDP) in osteosarcoma cells. A nanosized CDDP-loaded PLGA-DX nanoparticle (PLD/CDDP) controlled the release rate of CDDP up to 48 h. In vitro cytotoxicity assay s...

journal_title：Scientific reports

authors： Liu P,Sun L,Zhou DS,Zhang P,Wang YH,Li D,Li QH,Feng RJ

更新日期：2015-12-01 00:00:00

abstract：:The present research relates to a fusion protein comprising a chromogenic blue ultramarine protein (UM) bound to a keratin-based peptide (KP). The KP-UM fusion protein explores UM chromogenic nature together with KP affinity towards hair. For the first time a fusion protein with a chromogenic nature is explored as a h...

journal_title：Scientific reports

authors： Tinoco A,Antunes E,Martins M,Gonçalves F,Gomes AC,Silva C,Cavaco-Paulo A,Ribeiro A

更新日期：2019-10-01 00:00:00

abstract：:Short flashes of blue light (bioluminescence) from dinoflagellates can reduce copepod grazing of light-emitting cells. Other protective strategies against grazing are toxicity, reduced cell chain length and altered swimming patterns in different phytoplankton. Both toxicity and bioluminescence capacity in dinoflagella...

journal_title：Scientific reports

authors： Lindström J,Grebner W,Rigby K,Selander E

更新日期：2017-10-12 00:00:00