Abstract:
:Fatty acid ethyl esters (FAEE) are direct metabolites of ethanol and have been shown to be suitable markers for the evaluation of alcohol consumption. Previous research has suggested that the regular use of alcohol containing cosmetic products can influence the concentration of FAEE detected in hair. In this study we investigated the influence of alcohol containing and alcohol free hair cosmetics (hairspray and waxes) on the FAEE concentrations in hair. The effect of cosmetic treatment was measured against the impact on ethyl palmitate in isolation as compared to the sum of four esters. 10 volunteers treated part of their scalp with cosmetic products every day during a 2 month period (alcohol free hairspray n=2, hairspray containing alcohol (42% by volume) n=3, alcohol free wax n=2, wax containing alcohol (11% by volume) n=3). After the 2 month period of cosmetic application hair samples from volunteers were collected from both sides of the scalp. Hair samples were washed with n-heptane, and then cut finely into small pieces. All samples were subjected to clean-up by HS-SPME and then GC PCI-MS/MS for analysis of FAEEs. Comparison of FAEE concentrations between treated and untreated hair showed in some instances that application of hair spray or wax products caused an increase in FAEE levels. Products containing alcohol caused a more substantial increase in alcohol metabolite concentrations in hair when compared to alcohol free products. Three volunteers using an alcohol based hairspray in the study experienced a significant increase in FAEE levels (+27.4%, +205.5%, and +1287.5%), with one of the volunteers showing levels below the cut off for 'abstinence' in the untreated scalp portion, and levels above the cut off for 'chronic excessive consumption' in the treated scalp portion. Performance evaluation of ethyl palmitate as sole marker, compared to the sum of four esters approach suggested that the two quantification approaches react in a very similar manner to the application of hair sprays and waxes. We would suggest that the interpretative value of FAEE hair measurements from people reporting the use of alcohol based hairsprays are treated with caution.
journal_name
Forensic Sci Intjournal_title
Forensic science internationalauthors
Dumitrascu C,Paul R,Kingston R,Williams Rdoi
10.1016/j.forsciint.2017.12.002subject
Has Abstractpub_date
2018-02-01 00:00:00pages
29-34eissn
0379-0738issn
1872-6283pii
S0379-0738(17)30509-1journal_volume
283pub_type
杂志文章abstract::The judicial system calls upon expert witnesses to testify in court when complex or specialized knowledge, beyond that of the lay person, is needed to interpret the evidence. Previous research has indicated that particular traits of the expert witness can affect their credibility in the eyes of the jury, however most ...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2018.07.030
更新日期:2018-10-01 00:00:00
abstract::In this paper, a high performance liquid chromatographic method with fluorescence detection (HPLC-FL) for the determination of fenfluramine (Fen) and norfenfluramine (Norf) in human hair as biomarker metabolites of N-nitrosofenfluramine (N-Fen) is described. Washed and cut hair segments were extracted by ultrasonicati...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2004.03.018
更新日期:2004-11-10 00:00:00
abstract::Gamma-hydroxybutyric acid's (GHB's) natural presence in the body has made the interpretation of its levels a challenging task for the forensic toxicologist. This study was designed to measure endogenous GHB levels in antemortem urine and blood samples. The range detected in urine was from 34 to 575 microg/dl and in bl...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/s0379-0738(02)00183-4
更新日期:2002-08-28 00:00:00
abstract::We examined the immunohistochemical distributions of ubiquitin (Ub) and myoglobin (Mb) in human kidney tissues to assist the pathological assessment of death due to trauma. Medicolegal autopsy cases at our institute (n=138: 0-96 years of age, 105 males and 33 females) were examined. Causes of death were blunt injury (...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2006.10.016
更新日期:2007-09-13 00:00:00
abstract::This article discusses the immunoassay screening of pain management drugs, and the mass spectrometric confirmation of fentanyl in human hair. Hair specimens were screened for fentanyl, opiates (including oxycodone), tramadol, propoxyphene, carisoprodol, methadone, and benzodiazepines and any positive results were conf...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2007.06.027
更新日期:2008-03-21 00:00:00
abstract::Early in 2009, a state policing agency raided a clandestine drug laboratory in a suburb of a major city in Australia. During the search of the laboratory, a small glass jar labelled "Gamma Source" and containing a green powder was discovered. The powder was radioactive. This paper documents the detailed nuclear forens...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2014.04.004
更新日期:2014-07-01 00:00:00
abstract::Cranial suture closure has been recognized for over a century as a useful trait for age estimation. Although this indicator has become a standard feature of age assessment protocols in skeletal remains, serious questions have been raised about its reliability. This article attempts to provide a comprehensive review of...
journal_title:Forensic science international
pub_type: 历史文章,杂志文章,评审
doi:10.1016/j.forsciint.2019.110111
更新日期:2020-02-01 00:00:00
abstract::In developed countries, sudden infant death syndrome (SIDS) represents the most prevalent cause of death in children between 1 month and 1 year of age. SIDS is a diagnosis of exclusion, a negative autopsy which requires the absence of structural organ disease. Although investigators have confirmed that a significant p...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2012.01.018
更新日期:2012-06-10 00:00:00
abstract::The smuggling of illicit drugs by means of body packing has become a common problem at European airports. Europe is considered to be the fastest growing market for cocaine worldwide, and the air route is the most frequently used method of trafficking cocaine. Smuggling illicit drugs by use of body packing is considere...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/s0379-0738(99)00142-5
更新日期:2000-01-24 00:00:00
abstract::Based on the analysis of shrunken heads referred to our forensic laboratory for anthropological expertise, and data from both anthropological and medical literature, we propose a complete forensic procedure for the analysis of such pieces. A list of 14 original morphological criteria has been developed, based on the g...
journal_title:Forensic science international
pub_type: 历史文章,杂志文章
doi:10.1016/j.forsciint.2012.06.009
更新日期:2012-10-10 00:00:00
abstract::The AmpFlSTR Identifiler kit has recently been accepted for use in DNA databasing of forensic samples in the FBI's National DNA Index System. In the present study, we used this kit to analyze the allele distribution of 15 short tandem repeat markers (STR) in individuals living in Caracas city, Venezuela. The allele fr...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/s0379-0738(03)00259-7
更新日期:2003-09-09 00:00:00
abstract::Allele frequencies for 15 STR loci found in PowerPlex 16 System kit were determined in a sample of 200 unrelated individuals living in Sichuan area in west China. The values of observed heterozygosity (Ho), power of discrimination (PD), probability of paternity exclusion (PE) and polymorphism information content (PIC)...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2006.05.039
更新日期:2007-09-13 00:00:00
abstract::Although most cases involving entomological evidence occur in urban environments and under indoor conditions, there is a lack of studies determining the insect fauna of forensic importance in those environments. In the current paper we provide the first data on the composition of the forensically important insect spec...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2014.12.012
更新日期:2015-03-01 00:00:00
abstract::Obtaining palynological and other botanical evidence from murder victims is becoming part of routine mortuary protocol in the United Kingdom. Forensic pathologists are often keen to cooperate in the collection of classes of material that have, in the past, been considered to be of little importance in criminal investi...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2006.06.070
更新日期:2006-11-22 00:00:00
abstract::A 28-year-old male car driver was reported to suddenly loose the control over his vehicle, to hit the right and middle crash barrier, and to be unconscious as the car came to a halt in a position at right angles to the road. The car was hit in its left side by an automobile with high velocity, and the 28-year-old driv...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2007.02.016
更新日期:2007-12-20 00:00:00
abstract::Postmortem radiographic examinations of animals are often performed in judicial investigation to rule out gunshot and fractures due to cruelty. Literature describing postmortem changes seen on radiographs of animals is rarely available. Serial thoracic radiography of six recently euthanized dogs was performed in an in...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2009.03.031
更新日期:2009-07-01 00:00:00
abstract::Systematic autopsy was performed in 807 medicolegal deaths where the police had not requested autopsy. In all cases both the cause of death and the mode of death had been reported at the medicolegal external examination. The autopsy revealed differences in the mode of death in about 4% of all cases. This was due in pa...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/0379-0738(80)90190-5
更新日期:1980-01-01 00:00:00
abstract::Buprenorphine is available in Singapore as substitution treatment for opioid dependence since 2002. This study surveys buprenorphine related deaths in Singapore between September 2003 and December 2004. The aims are to establish the autopsy prevalence of buprenorphine related deaths and the demographical and toxicolog...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2006.03.037
更新日期:2006-10-16 00:00:00
abstract::Injuries caused by traffic accidents can be complex and extensive. Due to the highly dynamic course of actions, reconstructive questions may be challenging to investigators. Differentiation of a single collision from an overrun is a central question. We hypothesized that the existence of spine fractures such as spinou...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2012.01.013
更新日期:2012-06-10 00:00:00
abstract::We developed a q-PCR technique that simultaneously evaluates the extent of degradation and determines the gender of a human DNA donor. QYDEG HRM is a triplex real-time PCR whose products are analysed by high-resolution melting (HRM). The system produces three amplicons: (1) transducin (beta)-like 1, Y-linked (TBL1Y) (...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2018.11.013
更新日期:2019-02-01 00:00:00
abstract::The cyanide distribution in five fatal cyanide poisonings was analyzed by the pyridine-pyrazolone method using a Conway diffusion cell. In order to study the effect of storage conditions on cyanide concentration in tissue samples, the cyanide concentrations were first measured immediately after collection of the sampl...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/0379-0738(88)90164-8
更新日期:1988-09-01 00:00:00
abstract::The application of europium luminescence to the visualisation of cyanoacrylate developed fingerprints is reported. Extremely fluorescent europium chelates are produced by the reaction of Eu3+ ions with aryl-beta-diketones. Excitation of the organic ligand occurs at 350 nm for europium tris(thenoyltrifluoroacetone) (TE...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/0379-0738(93)90094-q
更新日期:1993-06-01 00:00:00
abstract::Usefulness of portable, handheld breath analysers equipped with electrochemical sensor was assessed. Breath- and blood-alcohol concentrations in drunken drivers were taken from 370 expert opinions elaborated at the Institute of Forensic Research between January 1st 2002 and February 28th 2007. The results of second an...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2008.03.002
更新日期:2008-07-04 00:00:00
abstract:AIMS:The aim of this work is to test the stability of mephedrone added to whole blood collected from alive and dead mephedrone free-users and stored at three different temperatures (-20, +4 and +20°C) with and without preservatives up to 6 months, trying to establish the best storage condition in order to reduce possib...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2015.07.021
更新日期:2015-11-01 00:00:00
abstract::Diastereomeric dipeptides were derived from the amino acid enantiomers in dentin by O-phthalaldehyde-N-acetyl-L-cysteine. The products were separated using high performance liquid chromatography (HPLC) and detected by fluorescence detector. A short analysis time (total analysis time was 15 min, including retention tim...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/0379-0738(95)01709-7
更新日期:1995-05-09 00:00:00
abstract::Genomic DNA samples from 222 individuals from Southern China, 154 individuals from Thailand, 100 individuals from Japan as well as from 124 German individuals were analysed for the short tandem repeat (STR) locus D12S391. Typing was carried out by polymerase chain reaction (PCR) amplification and subsequent polyacryra...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/s0379-0738(98)00035-8
更新日期:1998-06-08 00:00:00
abstract::An investigation was made to determine the effects of age and sex on postmortem concentrations (mumol/l) of inosine, hypoxanthine, xanthine, uric acid, uracil and uridine in the vitreous humor of chickens (Gallus domesticus). Five male and 5 female chickens were sampled each week from 0-10 weeks of age. Samples were c...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/0379-0738(90)90206-e
更新日期:1990-09-01 00:00:00
abstract::The intradural sagittal diameter at the second cervical vertebra (SD/C2) of 62 SIDS cases was measured myelographically. This SD/C2 proved to be dependent on body size, body weight, and age. A clear, age-dependent difference is to be found in the primarily narrow spinal canal. This parameter (SD/C2), which is more pre...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/0379-0738(86)90184-2
更新日期:1986-07-14 00:00:00
abstract::A novel 39-plex typing system for single nucleotide polymorphisms (SNPs) has been developed. This multiplex approach has the advantage of being able to type 38 autosomal SNPs and one sex-discriminating base exchange site on the X and Y chromosomes rapidly and simultaneously. The SNP loci on the autosomes, which we exa...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2004.03.005
更新日期:2004-08-11 00:00:00
abstract::In autopsy files from April 1999 to April 2001, five cases showed macroscopic subendocardial small infarct above 1 cm diameter in the superior ventricular septum (SVS) near the atrioventricular (AV) junction, and all five were finally considered to be sudden cardiac death after full investigation. All these small infa...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2003.08.006
更新日期:2003-12-17 00:00:00