Fatal head injury in children.

abstract：AIM:To investigate the association between the quantity of gastric chemokine mRNA expression, severity of gastritis, and cagA positivity in Helicobacter pylori associated gastritis. METHODS:In 83 dyspeptic patients, antral and corpus biopsies were taken for semiquantitative reverse transcription polymerase chain react...

journal_title：Journal of clinical pathology

authors： Shimoyama T,Everett SM,Dixon MF,Axon AT,Crabtree JE

更新日期：1998-10-01 00:00:00

abstract：:It was shown that, on average, the titres of the sera obtained by both the anti-complement immunofluorescence (ACIF) and indirect immunofluorescence for viral late antigens (IFA-LA) procedures were approximately eight times higher than those obtained by complement fixation. There was no significant difference between ...

journal_title：Journal of clinical pathology

authors： Griffiths PD,Buie KJ,Heath RB

更新日期：1978-09-01 00:00:00

abstract：:Microsatellite instability (MSI) testing is tricky in gynaecological cancers (GC). Thus, we aimed to describe the instability patterns to improve MSI test interpretation in sporadic and hereditary GCs. Ninety-five cases, including uterine and ovarian cancers, with known genetic and immunohistochemical (IHC) features, ...

journal_title：Journal of clinical pathology

authors： Libera L,Sahnane N,Carnevali IW,Cimetti L,Cerutti R,Chiaravalli AM,Riva C,Tibiletti MG,Sessa F,Furlan D

更新日期：2017-09-01 00:00:00

abstract：AIMS:The miR-9 family microRNAs (miRNAs) are tumour suppressor miRNAs implicated in carcinogenesis. We postulated that miR-9-1, miR-9-2 and miR-9-3 may be inactivated by aberrant promoter methylation in multiple myeloma (MM). METHODS:Methylation of miR-9-1, miR-9-2 and miR-9-3 was studied by methylation-specific PCR (...

journal_title：Journal of clinical pathology

authors： Zhang Q,Wang LQ,Wong KY,Li ZY,Chim CS

更新日期：2015-07-01 00:00:00

abstract：:A case of IgD myeloma accompanied by diffuse osteosclerosis is reported. A trephine biopsy specimen showed only reticulin fibrosis, but histomorphometric analysis of a full thickness transiliac bone biopsy specimen showed increased trabecular bone mass, with no local deposit of tumour. An excess of bone surfaces were ...

journal_title：Journal of clinical pathology

authors： MacCallum PK,Freemont AJ,Geary CG,Liu Yin JA

更新日期：1988-05-01 00:00:00

abstract：:A severe non-dose related skin eruption attributable to treatment with captopril was recently reported: this is distinct from the dose related rashes that have been widely described. Ultrastructural and immunohistochemical studies were carried out to determine in detail the histological features of this eruption: the ...

journal_title：Journal of clinical pathology

authors： Furness PN,Goodfield MJ,MacLennan KA,Stevens A,Millard LG

更新日期：1986-08-01 00:00:00

abstract：:In colonic biopsies of 33 patients with acute colitis caused by campylobacter, salmonella, or shigella immunoglobulin containing cells were determined quantitatively using an indirect immunoperoxidase technique and morphometry with a graphic tablet. The findings were compared with those of 10 patients without histolog...

journal_title：Journal of clinical pathology

authors： van Spreeuwel JP,Lindeman J,Meijer CJ

更新日期：1985-07-01 00:00:00

abstract：AIM:To compare the sensitivity and staining pattern of the new immunohistochemical antibody to tyrosinase (T311) with S-100, HMB45, and the recently evaluated antibody to melan-A (A103) in a range of melanocytic lesions. METHOD:Archival, formalin fixed, paraffin wax embedded sections from 50 benign and malignant melan...

journal_title：Journal of clinical pathology

authors： Clarkson KS,Sturdgess IC,Molyneux AJ

更新日期：2001-03-01 00:00:00

abstract：AIMS:The macroH2A histone variants are epigenetic marks for inactivated chromatin. In this study, we examined the expression of macroH2A2 in anal neoplasm from anal intraepithelial neoplasia (AIN) to anal squamous cell carcinoma (SCC). METHODS:AIN and anal SCC samples were analysed for macroH2A2 expression, HIV and hu...

journal_title：Journal of clinical pathology

authors： Hu WH,Miyai K,Sporn JC,Luo L,Wang JY,Cosman B,Ramamoorthy S

更新日期：2016-07-01 00:00:00

abstract：:The effect of acute hypoglycaemia on platelet function was examined in patients undergoing an insulin stress test. Enhanced platelet aggregation was observed in all cases but platelet count, platelet adenine nucleotides, and the plasma level of von Willebrand factor were unchanged overall. The onset of the hypoglycaem...

journal_title：Journal of clinical pathology

authors： Hutton RA,Mikhailidis D,Dormandy KM,Ginsburg J

更新日期：1979-05-01 00:00:00

abstract：:In patients with chronic renal failure, blood samples for laboratory analysis are often taken via dialysis catheters. This report describes a case of gross spurious hypernatraemia in a blood sample collected from a patient undergoing haemodialysis. After centrifugation of the blood sample in question, the separator ge...

journal_title：Journal of clinical pathology

authors： Srivastava R,Murphy MJ,Card J,Severn A,Fraser CG

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Prostate cancer diagnosis is routinely made by the histopathological examination of formalin fixed needle biopsy specimens. Frequently this is the only cancer tissue available from the patient for the analysis of diagnostic and prognostic biomarkers. There is, therefore, an urgent need for methods that allow...

journal_title：Journal of clinical pathology

authors： McCarthy F,Fletcher A,Dennis N,Cummings C,O'Donnell H,Clark J,Flohr P,Vergis R,Jhavar S,Parker C,Cooper CS

更新日期：2009-08-01 00:00:00

abstract：:A patient with rhabdomyosarcoma is described in whom the presenting clinical and laboratory features were those of disseminated intravascular coagulation. The patient's rapid downhill course was primarily expressed by haemorrhagic tendency. An alveolar rhabdomyosarcoma, affecting many organs, including vascular and ca...

journal_title：Journal of clinical pathology

authors： Eldor A,Naparstek E,Boss JH,Biran S

更新日期：1977-07-01 00:00:00

abstract：:The clinical and pathological findings in 23 patients with ischaemic lesions of the alimentary tract (ischaemic enterocolitis) are described. These are compared with findings in 13 patients with occlusive thrombosis of the superior mesenteric artery. The pathological features distinguishing the two conditions are disc...

journal_title：Journal of clinical pathology

authors： McDonald GS,Hourihane DO

更新日期：1972-02-01 00:00:00

abstract：AIM:Lymphocytic infiltration in the portal triads usually conceals the detection--in haematoxylin and eosin (H&E) stained sections--of bile ducts in two liver diseases: chronic hepatitis and primary biliary cirrhosis. The aim was to assess the number and the characteristics of the bile ducts in those diseases with the ...

journal_title：Journal of clinical pathology

authors： Rubio CA

更新日期：2000-10-01 00:00:00

abstract：:The results of a histological study of normal osteoid tissue in man, the monkey, the dog, and the rat, using thin microtome sections of plastic-embedded undecalcified bone, are described. Osteoid tissue covers the entire bone surface, except for areas of active resorption, although the thickness of the layer of osteoi...

journal_title：Journal of clinical pathology

authors： Raina V

更新日期：1972-03-01 00:00:00

abstract：AIMS:To develop a quantitative reverse transcriptase polymerase chain reaction (Q-RT-PCR) for severe acute respiratory syndrome coronavirus (SARS-CoV) detection and explore the potential of using glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA as an internal control to exclude false negative results. METHODS:SAR...

journal_title：Journal of clinical pathology

authors： Wong SC,Chan JK,Lee KC,Lo ES,Tsang DN

更新日期：2005-03-01 00:00:00

abstract：:This review of the histomorphometry of bone outlines methods of biopsy and processing of specimens in the laboratory, the basic principles of morphometry, and the measurements made in order to obtain estimates of the proportional volumes and surfaces occupied by different components of bone. Variability such as that b...

journal_title：Journal of clinical pathology

authors： Revell PA

更新日期：1983-12-01 00:00:00

abstract：AIM:To evaluate the use of multimedia enhancements, using a computerised microscope, in the training of microscope skills. METHODS:The HOME microscope provides facilities to highlight features of interest in conjunction with either text display or aural presentation. A pilot study was carried out with 10 individuals, ...

journal_title：Journal of clinical pathology

authors： Gray E,Duvall E,Sprey J,Bird CC

更新日期：1998-04-01 00:00:00

abstract：AIMS:Guaiac faecal occult blood tests are being replaced by faecal immunochemical tests (FIT). We investigated whether faecal haemoglobin concentration (f-Hb) was related to stage in progression of colorectal neoplasia, studying cancer and adenoma characteristics in an evaluation of quantitative FIT as a first-line scr...

journal_title：Journal of clinical pathology

authors： Digby J,Fraser CG,Carey FA,McDonald PJ,Strachan JA,Diament RH,Balsitis M,Steele RJ

更新日期：2013-05-01 00:00:00

abstract：:Twelve methods for the demonstration of bacterial penicillinase production by strains of Haemophilus influenzae and Staphylococcus aureus are compared, and their suitability for routine clinical laboratory use is evaluated. The acidometric agar plate method is recommended. ...

journal_title：Journal of clinical pathology

authors： Lucas TJ

更新日期：1979-10-01 00:00:00

abstract：AIMS:To examine neuroendocrine differentiation, as shown by chromogranin A (CGA) expression, in cervical carcinomas. METHODS:Sixty seven cervical carcinomas were studied and were classified as adenocarcinomas, adenosquamous carcinomas or squamous cell carcinomas based on the assessment of haematoxylin and eosin staini...

journal_title：Journal of clinical pathology

authors： Savargaonkar PR,Hale RJ,Mutton A,Manning V,Buckley CH

更新日期：1996-02-01 00:00:00

abstract：:Chromosome studies were attempted on 97% of necropsies carried out in the Department of Histopathology of the Adelaide Children's Hospital over the four-year period ending May 1981. Results were obtained from 89% of necropsies of which 7.5% had major chromosome abnormalities. The chromosome results are analysed accord...

journal_title：Journal of clinical pathology

authors： Sutherland GR,Carter RF

更新日期：1983-02-01 00:00:00

abstract：:Experiments are described with glass fibre filter paper and complete glass filters as fitted to high pre-vacuum autoclaves to determine whether organisms can grow or penetrate through the filters. A filter consisting of four layers of glass fibre paper fitted inside a sterilizer chamber for a year and used for 96 ster...

journal_title：Journal of clinical pathology

authors： Fallon RJ

更新日期：1963-05-01 00:00:00

abstract：AIM:To examine tumour samples immunohistochemically for MUC1 (episialin), epidermal growth factor receptor (EGFR), and c-erbB-2, since the disruption of the cell-cell adhesion system by MUC1 and the c-erbB oncoprotein family is known to be important in the development of metastasis in human cancers. METHODS:93 tumour ...

journal_title：Journal of clinical pathology

authors： Guddo F,Giatromanolaki A,Koukourakis MI,Reina C,Vignola AM,Chlouverakis G,Hilkens J,Gatter KC,Harris AL,Bonsignore G

更新日期：1998-09-01 00:00:00

abstract：:A method for identifying Helicobacter pylori using a non-isotopic in situ hybridisation technique is described. A probe generated by polymerase chain reaction (PCR) with primers directed against parts of the Helicobacter pylori 16SrRNA sequence was used. Paraffin wax embedded gastric biopsy specimens from patients wit...

journal_title：Journal of clinical pathology

authors： Bashir MS,Lewis FA,Quirke P,Lee A,Dixon MF

更新日期：1994-09-01 00:00:00

abstract：AIM:To develop a simple but reliable polymerase chain reaction (PCR) method to determine the HIV-1 status of patients on formalin fixed, paraffin wax embedded lymph node tissue. METHODS:Fifty lymph node specimens, 20 from HIV-1 seropositive and 30 from HIV-1 seronegative patients, were analysed. Lymph nodes with a var...

journal_title：Journal of clinical pathology

authors： Slavik T,Wolfaardt M,van Zyl H,Simson IW

更新日期：1995-08-01 00:00:00

abstract：:Antigenic extracts were prepared from Aspergillus fumigatus, A niger, A flavus and A terreus for use in enzyme linked immunosorbent assay (ELISA) and immunodiffusion (ID) tests for Aspergillus antibodies to determine whether the use of antigenic extracts from species other than A fumigatus increased the sensitivity of...

journal_title：Journal of clinical pathology

authors： Froudist JH,Harnett GB,McAleer R

更新日期：1989-11-01 00:00:00

abstract：:As part of a wider survey of infections and defence mechanisms, concentrations of serum immunoglobulins IgG, IgA, and IgM were measured regularly by single radial immunodiffusion in a group of children receiving treatment for acute lymphoblastic leukaemia while in their first remission. IgM concentrations were often m...

journal_title：Journal of clinical pathology

authors： Reid MM,Craft AW,Cox JR

更新日期：1981-05-01 00:00:00

abstract：:The activities of phosphohexose isomerase and 6-phosphogluconate dehydrogenase have been studied in the vaginal fluid of women from the gynaecological departments. Women from these departments gave a very high false positive rate, though no cases of carcinoma in situ were not detected by estimating phosphohexose isome...

journal_title：Journal of clinical pathology

authors： Muir GG

更新日期：1966-07-01 00:00:00