Platelet aggregation studies during transient hypoglycaemia: a potential method for evaluating platelet function.

abstract：AIM:Primary biliary cirrhosis (PBC) is characterised by antimitochondrial antibody against the pyruvate dehydrogenase complex (PDC) and chronic non-suppurative destructive cholangitis (CNSDC). Pyruvate oxidation to acetyl-CoA by PDC is a key step in the glycolytic system. Oestrogen-related receptor-α (ERRα) is function...

journal_title：Journal of clinical pathology

authors： Harada K,Kakuda Y,Sato Y,Ikeda H,Shimoda S,Yamamoto Y,Inoue H,Ohta H,Kasashima S,Kawashima A,Nakanuma Y

更新日期：2014-05-01 00:00:00

abstract：AIMS:Evidence suggests that the presence of tumour necrosis is an adverse prognostic factor in renal cell carcinoma (RCC). However, it has also been shown that tumour regression, a microscopic feature associated with necrosis, may be a favourable short term prognostic factor in RCC. METHODS:Pathology reports of 253 RC...

journal_title：Journal of clinical pathology

authors： Foria V,Surendra T,Poller DN

更新日期：2005-01-01 00:00:00

abstract：:In an investigation of the in vitro phagocytic and microbicidal function of granulocytes collected by filtration leucapheresis (FL) from 18 donors and by discontinuous flow centrifugation leucapheresis (DFC) from six donors, comparison was made with the function of granulocytes obtained from the same donors by venepun...

journal_title：Journal of clinical pathology

authors： Martin S,Ghoneim AT,Robinson EA,Child JA

更新日期：1983-05-01 00:00:00

abstract：:Mallory bodies were isolated from necropsy livers from patients with alcoholic hepatitis with and without cirrhosis with a Ficoll viscosity barrier. The purity of Mallory bodies in the isolate varied between 70 and 90%, estimated by counting Mallory bodies and non-Mallory body structures in haematoxylin-eosin stained ...

journal_title：Journal of clinical pathology

authors： Gluud C,Hardt F,Aldershvile J,Christoffersen P,Lyon H,Nielsen J

更新日期：1981-09-01 00:00:00

abstract：:A rapid and reproducible technique for in situ hybridisation, using biotin labelled probes for the Y chromosome, human DNA, hepatitis B virus DNA and cytomegalovirus DNA on formalin fixed, paraffin embedded liver tissue, was developed. The degree of proteolytic digestion of tissue specimens is critical to ensure adequ...

journal_title：Journal of clinical pathology

authors： Naoumov NV,Alexander GJ,Eddleston AL,Williams R

更新日期：1988-07-01 00:00:00

abstract：AIMS:The aim of this study was to assess the prevalence and drug resistance of Ureaplasma species and Mycoplasma hominis in outpatients with genital manifestation from 2005 to 2013 in Hangzhou, China. METHODS:A total of 2689 female and 2336 male patients with various genital symptoms were included in this study. Speci...

journal_title：Journal of clinical pathology

authors： Song T,Ye A,Xie X,Huang J,Ruan Z,Kong Y,Song J,Wang Y,Chen J,Zhang J

更新日期：2014-09-01 00:00:00

abstract：:The use of liquid media to detect the production of beta-lactamase by beta-lactamase producing organisms has been compared with the conventional method of inoculation on to agar media. Pharyngeal cultures were obtained from 162 children treated with penicillin for acute tonsillitis. beta-lactamase producing organisms ...

journal_title：Journal of clinical pathology

authors： Brook I,Gober AE

更新日期：1984-12-01 00:00:00

abstract：AIMS:To assess the effect of cellulosic dialysis membranes on the production of complement degradation products to determine to the role of the classical pathway. METHOD:Complement activation was studied in 33 patients during a single haemodialysis session using cellulosic membranes. Pre- and post-dialysis plasma EDTA...

journal_title：Journal of clinical pathology

authors： Innes A,Farrell AM,Burden RP,Morgan AG,Powell RJ

更新日期：1994-02-01 00:00:00

abstract：INTRODUCTION:Bone marrow aspiration and biopsy is an invasive procedure associated with morbidity and mortality risk. We compared a powered bone marrow aspiration and biopsy device to the traditional method by relatively assessing pain scores, procedure times, biopsy capture rates, quality of material retrieved, and sa...

journal_title：Journal of clinical pathology

authors： Swords RT,Anguita J,Higgins RA,Yunes AC,Naski M,Padmanabhan S,Kelly KR,Mahalingam D,Philbeck T,Miller L,Puga TA,Giles FJ,Kinney MC,Brenner AJ

更新日期：2011-09-01 00:00:00

abstract：AIMS:The purpose of this study was to compare the DNA-methylation signature in classic chronic Philadelphia negative myeloproliferative neoplasms (MPN), polycythaemia vera (PV) and essential thrombocythaemia (ET), in order to obtain a global insight into DNA-methylation changes associated with these malignancies. METH...

journal_title：Journal of clinical pathology

authors： Barrio S,Gallardo M,Albizua E,Jimenez A,Rapado I,Ayala R,Gilsanz F,Martin-Subero JI,Martinez-Lopez J

更新日期：2011-11-01 00:00:00

abstract：:Aneuploidy is frequently noted in malignant tumours. There is much controversy about its cause and effect in relation to malignant tumours. Failure of the spindle checkpoint caused by mutation of the responsible genes may be one of the important factors for the development of aneuploidy. Telomere dysfunction may also ...

journal_title：Journal of clinical pathology

authors： Dey P

更新日期：2004-12-01 00:00:00

abstract：:Serum total calcium was measured in 1693 patients during a four-month period. We examined the effects of adjustment for albumin concentration on the interpretation of single measurements of serum total calcium and on the variation of series of measurements in individual patients. Markedly abnormal total calcium concen...

journal_title：Journal of clinical pathology

authors： Payne RB,Carver ME,Morgan DB

更新日期：1979-01-01 00:00:00

abstract：:Experience after 18 months' work with the SMA-4 system of multiple analysis for routine haematology is described, as well as the modifications to the machine which have been made for smoother operation. ...

journal_title：Journal of clinical pathology

authors： Green AE,Middleton VL,Prentis KG,Signy AG

更新日期：1969-01-01 00:00:00

abstract：AIMS:To determine whether myelodysplastic syndromes (MDS) are associated with sea blue histiocytosis in the bone marrow. METHODS:A retrospective review of bone marrow aspirates from 35 patients presenting consecutively with MDS and from 20 patients with each of the following: normal marrow appearance (routine staging ...

journal_title：Journal of clinical pathology

authors： Howard MR,Kesteven PJ

更新日期：1993-11-01 00:00:00

abstract：:Platelet adhesiveness was measured in patients undergoing operation. With the rotating bulb technique adhesiveness increased steadily to the sixth and ninth days following surgery. The glass bead filter technique demonstrated a marked increase in platelet adhesiveness on the day following operation. ...

journal_title：Journal of clinical pathology

authors： Bennett PN

更新日期：1967-09-01 00:00:00

abstract：AIMS:Congenital neutropenia (CN) is a rare inherited disease that results in recurrent, life-threatening bacterial infections due to a deficiency of mature neutrophils. They are usually caused by heterozygous ELANE mutations although mutations in other genes like HAX-1, G6PC3 and GFI1 have also been reported. Identifyi...

journal_title：Journal of clinical pathology

authors： Arunachalam AK,Suresh H,Edison ES,Korula A,Aboobacker FN,George B,Shaji RV,Mathews V,Balasubramanian P

更新日期：2020-06-01 00:00:00

abstract：:An enzyme immunoassay technique based on the direct detection of Chlamydia trachomatis antigen in urethral or cervical swabs was used for the rapid diagnosis of chlamydial genital infection. Urethral and cervical samples from 140 patients were tested in parallel by enzyme immunoassay and cell culture using iodine stai...

journal_title：Journal of clinical pathology

authors： Mumtaz G,Mellars BJ,Ridgway GL,Oriel JD

更新日期：1985-07-01 00:00:00

abstract：:Of the 123 patients with acute mesenteric infarction treated over the past 12 years, 16 (13%) had mesenteric venous thrombosis. Eight of the patients with mesenteric venous thrombosis survived the initial episode; two have since died. The remaining six patients were studied for evidence of haemostatic deficiencies or ...

journal_title：Journal of clinical pathology

authors： Wilson C,Walker ID,Davidson JF,Imrie CW

更新日期：1987-08-01 00:00:00

abstract：:A prospective study of bone marrow fibrosis was made in a group of 40 children with acute lymphoblastic leukaemia to see whether it affected the prognosis or course of the disease. Secondary myelofibrosis (SMF) was present at diagnosis in 57% of the cases. It was not statistically significantly related to the prognosi...

journal_title：Journal of clinical pathology

authors： Hann IM,Evans DI,Marsden HB,Jones PM,Palmer MK

更新日期：1978-04-01 00:00:00

abstract：:A full surface marker study of the splenic storage cells in a case of Gaucher's disease largely substantiates the monocyte/histiocyte nature of Gaucher's cells. In addition, an apparent T-lymphocyte deficiency is demonstrated in the spleen and peripheral blood, and the possible significance of this finding is discusse...

journal_title：Journal of clinical pathology

authors： Burns GF,Cawley JC,Flemans RJ,Higgy KE,Worman CP,Barker CR,Roberts BE,Hayhoe FG

更新日期：1977-10-01 00:00:00

abstract：AIMS:The aim of the present study was to immunohistochemically investigate the expression and prognostic significance of putative cancer stem cell markers CD117 (c-kit), CD34, CD20 and CD15 in a cohort of patients with primary choroidal and ciliary body melanoma. METHODS:The immunohistochemical expression of these mar...

journal_title：Journal of clinical pathology

authors： Lukenda A,Dotlic S,Vukojevic N,Saric B,Vranic S,Zarkovic K

更新日期：2016-03-01 00:00:00

abstract：:Serum glutamic oxalacetic transaminase (G-OT), glutamic-pyruvic transaminase (G-PT), and isocitric dehydrogenase (ICD) have been estimated in six groups of subjects, namely, normal British adults, normal Nigerian adults, undernourished Nigerian adults and children, Nigerian children with florid protein malnutrition (k...

journal_title：Journal of clinical pathology

authors： BARON DN

更新日期：1960-05-01 00:00:00

abstract：AIMS:To determine the prognostic usefulness of the Nottingham histological grade (NHG) and its components in a series of 270 patients with stage pT1N0M0 breast cancer with a median follow up of 12.5 years. METHODS:Microscopic slides were re-examined and the degree of tubule formation, nuclear pleomorphism, and mitotic...

journal_title：Journal of clinical pathology

authors： Frkovic-Grazio S,Bracko M

更新日期：2002-02-01 00:00:00

abstract：:Staphylococcus aureus isolated between 1967 and 1975 from the nose and skin lesions of patients in dermatology wards and from the burns of patients in a burns unit in Birmingham showed a high incidence of multiple antibiotic-resistant strains in both environments. Over 20% of the strains isolated from patients on admi...

journal_title：Journal of clinical pathology

authors： Ayliffe GA,Green W,Livingston R,Lowbury EJ

更新日期：1977-01-01 00:00:00

abstract：AIMS:The Royal College of Pathologists recommend that a median of at least 12 lymph nodes should be harvested during pathological staging of colorectal cancer. It is not always easy to harvest the required number, especially in patients with rectal cancer receiving neoadjuvant therapy. Lymph node revealing solutions, f...

journal_title：Journal of clinical pathology

authors： Horne J,Carr NJ,Bateman AC,Kandala N 2nd,Adams J,Silva S,Ryder I

更新日期：2016-06-01 00:00:00

abstract：:Hereditary breast cancer accounts for up to 5-10% of all breast carcinomas. Recent studies have demonstrated that mutations in two high-penetrance genes, namely BRCA1 and BRCA2, are responsible for about 16% of the familial risk of breast cancer. Even though subsequent studies have failed to find another high-penetran...

journal_title：Journal of clinical pathology

authors： Tan DS,Marchiò C,Reis-Filho JS

更新日期：2008-10-01 00:00:00

abstract：:Serum C reactive protein concentrations measured by a laboratory based assay were compared with the semiquantitative results obtained with a visual agglutination method (Well-cotest, CRP kit). Using this agglutination kit, diluting serum 1/10 and 1/20 gave C reactive protein results which could be of more clinical val...

journal_title：Journal of clinical pathology

authors： Richards NP,Elliott TS,Powell RJ,O'Callaghan C,Franklin P

更新日期：1985-04-01 00:00:00

abstract：:A patient with rhabdomyosarcoma is described in whom the presenting clinical and laboratory features were those of disseminated intravascular coagulation. The patient's rapid downhill course was primarily expressed by haemorrhagic tendency. An alveolar rhabdomyosarcoma, affecting many organs, including vascular and ca...

journal_title：Journal of clinical pathology

authors： Eldor A,Naparstek E,Boss JH,Biran S

更新日期：1977-07-01 00:00:00

abstract：:A case of acute myelomonocytic leukaemia (AMMOL) is reported in which skin infiltration with xanthomatous nodules was the presenting feature. The histological, including ultrastructural, appearances are described. ...

journal_title：Journal of clinical pathology

authors： O'Donnell JR,Tansey P,Chung P,Burnett AK,Thomson J,McDonald GA

更新日期：1982-11-01 00:00:00

abstract：AIMS:The aims of this study were (1) to determine the measurement accuracy of a widely used guaiac faecal occult blood test (gFOBT) compared with an immunochemical faecal occult blood test (iFOBT) during in vitro studies, including their analytical stability over time at ambient temperature and at 4°C; and (2) to compa...

journal_title：Journal of clinical pathology

authors： Lee CS,O'Gorman P,Walsh P,Qasim A,McNamara D,O'Morain CA,Boran GP

更新日期：2011-06-01 00:00:00