Alveolar rhabdomyosarcoma presenting as subacute intravascular coagulation.

abstract：:A method for the simultaneous labelling of terminal deoxynucleotidyl transferase (TdT) and membrane antigens is described. TdT is visualised in the cell nucleus with the peroxidase-antiperoxidase (PAP) method, and the immunogold method is used in combination with monoclonal antibodies against membrane antigens. The mo...

journal_title：Journal of clinical pathology

authors： Tavares de Castro J,San Miguel JF,Soler J,Catovsky D

更新日期：1984-06-01 00:00:00

abstract：AIMS:Heightened B-cell receptor (BCR) activity in diffuse large B-cell lymphoma (DLBCL) is well established, and a subset of patients with relapsed DLBCL can benefit from BCR-targeted therapies. Universal outreach of such emerging therapies mandates forming a global landscape of BCR molecular signalling in DLBCL, inclu...

journal_title：Journal of clinical pathology

authors： Masir N,Akhter A,Roshan TM,Florence CS,Abdul-Rahman F,Tumian NR,Kean-Chang P,Elyamany G,Shabani-Rad MT,Mansoor A

更新日期：2019-09-01 00:00:00

abstract：:Agar gel, cellulose acetate, and starch gel electrophoresis are all capable of diagnosing sickle-cell anaemia, sickle-cell haemoglobin C disease, and haemoglobin C disease in cord blood samples. Of these three electrophoretic techniques, agar gel is the easiest to interpret.Paper electrophoresis can reliably and rapid...

journal_title：Journal of clinical pathology

authors： Yaswon GI,Huntsman RG,Metters JS

更新日期：1970-09-01 00:00:00

abstract：:This report describes a case of refractory enteropathy with circulating intestinal goblet cell autoantibodies (IGA). A 19 year old man with hyperthyroidism had suffered from protracted diarrhoea for nearly 10 years. Histological examination showed evidence of collagenous enterocolitis. The diarrhoea did not improve de...

journal_title：Journal of clinical pathology

authors： Hori K,Fukuda Y,Tomita T,Kosaka T,Tamura K,Nishigami T,Kubota A,Shimoyama T

更新日期：2003-08-01 00:00:00

abstract：:A simple laboratory method for culture of continuous ambulatory peritoneal dialysis (CAPD) fluids is described. Guidelines for antimicrobial therapy are discussed based on results from 18 patients studied over an 11-week period. Cephalosporins appeared to be a rational choice for therapy while awaiting laboratory resu...

journal_title：Journal of clinical pathology

authors： Fenton P

更新日期：1982-11-01 00:00:00

abstract：BACKGROUND:Serine peptidase inhibitor Kazal type-1 (SPINK1), a trypsin kinase inhibitor, has well established associations with inflammation, cancer cell proliferation and carcinogenesis. However, the role of SPINK1 has not been investigated in stage IV colorectal cancer (CRC) patients receiving cetuximab based targete...

journal_title：Journal of clinical pathology

authors： Chen YT,Tsao SC,Tsai HP,Wang JY,Chai CY

更新日期：2016-04-22 00:00:00

abstract：:The degree of inflammation in the trachea, bronchi, and lungs of 139 cot deaths has been analysed and each case allocated to one of four groups. In group I the changes were considered to be serious enough to have caused death, while group II cases showed similar abnormalities but of a less severe nature, and in this g...

journal_title：Journal of clinical pathology

authors： Tapp E,Jones DM,Tobin JO

更新日期：1975-11-01 00:00:00

abstract：BACKGROUND/AIMS:Mast cells, when activated, secrete a large number of fibrogenic factors and have been implicated in the development of fibrotic conditions of the liver, lung, and skin. There is evidence that renal fibrosis is closely linked with a chronic inflammatory cell infiltrate within the interstitium, but a pot...

journal_title：Journal of clinical pathology

authors： Roberts IS,Brenchley PE

更新日期：2000-11-01 00:00:00

abstract：:Tumour associated antigens recognised by cellular or humoral effectors of the immune system are potential targets for antigen specific cancer immunotherapy. Different categories of cancer antigens have been identified that induce cytotoxic T lymphocyte (CTL) responses in vitro and in vivo, namely: (1) "cancer testis" ...

journal_title：Journal of clinical pathology

authors： Jäger D,Jäger E,Knuth A

更新日期：2001-09-01 00:00:00

abstract：:Factor VII levels have been measured in 100 patients with liver disease following parenteral vitamin K1 therapy. There was good agreement between specific factor VII measurements and the one-stage prothrombin time apart from six patients with compensated cirrhosis in whom the prothrombin time was prolonged despite the...

journal_title：Journal of clinical pathology

authors： Green G,Poller L,Thomson JM,Dymock IW

更新日期：1976-11-01 00:00:00

abstract：:Three cases of islet cell necrosis in neonates are reported. The association of this rare condition with antepartum haemorrhage, anoxia, shock and intravascular coagulation are discussed. The clinical and morphological appearances were compared with previous descriptions of this condition and an association with neona...

journal_title：Journal of clinical pathology

authors： Roberts PF

更新日期：1987-10-01 00:00:00

abstract：BACKGROUND/AIMS:A twofold increased risk for breast cancer has been reported recently for women with late onset diabetes. Most studies showed that there were differences in serum concentrations of insulin-like growth factors and related proteins between women with and without diabetes who have breast cancer. This study...

journal_title：Journal of clinical pathology

authors： Nardon E,Buda I,Stanta G,Buratti E,Fonda M,Cattin L

更新日期：2003-08-01 00:00:00

abstract：:Adenocarcinoma of the anal glands is very rare but it is an important lesion to recognise as with early diagnosis, it has an excellent prognosis. Because it involves the submucosa widely and penetrates the mucosa late, it can be mistaken for metastatic gastrointestinal carcinoma, or tumour arising in sinuses and fistu...

journal_title：Journal of clinical pathology

authors： Behan WM,Burnett RA

更新日期：1996-12-01 00:00:00

abstract：:Most patients with gonadoblastoma have dysgenetic gonads. This rare tumour has been described in three pregnant women. A fourth case in a 26 year old pregnant woman who presented with gonadoblastoma and dysgerminoma, is reported. She had a normal term pregnancy, 46XX chromosomes, normal genitalia, no history of menstr...

journal_title：Journal of clinical pathology

authors： Erhan Y,Toprak AS,Ozdemir N,Tiras B

更新日期：1992-09-01 00:00:00

abstract：:A method is described for the quantitative separation of radioactive bile acids and neutral sterols in human faeces on a potassium hydroxide-treated silicic acid column. Results obtained with faecal extracts containing metabolites derived from radioactive cholesterol, cholic acid, and chenodeoxycholic acid show that t...

journal_title：Journal of clinical pathology

authors： LEWIS B,MYANT NB

更新日期：1965-01-01 00:00:00

abstract：AIM:The evaluation of allelic losses at the FHIT and the BRCA1 genes and at three other loci at the 17q region in a series of 34 sporadic breast cancer cases from Southern Brazil. METHODS:The samples were evaluated for loss of heterozygosity (LOH) at the FHIT and the BRCA1 genes and at three other microsatellite marke...

journal_title：Journal of clinical pathology

authors： Santos SC,Cavalli LR,Cavalli IJ,Lima RS,Haddad BR,Ribeiro EM

更新日期：2004-04-01 00:00:00

abstract：:Fourteen formalin fixed and paraffin wax embedded biopsy specimens from 10 women (age range 34-68) presenting with pseudomembranous trigonitis were studied using a combination of anti-oestrogen receptor monoclonal antibodies in an avidin-biotin immunoperoxidase technique. All epithelial areas showing vaginal metaplasi...

journal_title：Journal of clinical pathology

authors： Stephenson TJ,Henry L,Harris SC,Giri DD,Fox M,Underwood JC

更新日期：1989-09-01 00:00:00

abstract：AIMS:To investigate staining patterns for mannan binding protein (MBP) by immunocytochemistry in liver biopsy specimens from patients with various hepatic disorders; to measure the serum MBP concentration in the patients at the time of biopsy; and to compare these to define further the role of MBP in disease. METHODS:...

journal_title：Journal of clinical pathology

authors： Ryley NG,Heryet AR,Lu J,Reid KB,Fleming KA

更新日期：1993-03-01 00:00:00

abstract：AIMS:To investigate the physical status of human papillomavirus 16 (HPV-16) in low grade squamous intraepithelial lesions (LSILs) as a means of determining the percentage of viral integration. METHODS:Ninety two LSIL/HPV positive Thin Prep(TM) samples were initially tested for the E6 gene by the polymerase chain react...

journal_title：Journal of clinical pathology

authors： Gallo G,Bibbo M,Bagella L,Zamparelli A,Sanseverino F,Giovagnoli MR,Vecchione A,Giordano A

更新日期：2003-07-01 00:00:00

abstract：:Isolates of Campylobacter jejuni, C coli, C fetus and C laridis were tested for agglutination reactions with a panel of five lectins: Arachis hypogaea, Bauhinia purpurea, Solanum tuberosum, Triticum vulgaris and Wisteria floribunda. Twenty three patterns of agglutination (lectin types) were recorded among 376 isolates...

journal_title：Journal of clinical pathology

authors： O'Sullivan N,Benjamin J,Skirrow MB

更新日期：1990-11-01 00:00:00

abstract：AIM:Recent events surrounding postmortem practices have necessitated several changes in the way necropsies are conducted both within the medicolegal and hospital settings. These changes have resulted in a striking reduction in the frequency of brain retention for neuropathological examination. Aberdeen Royal Infirmary,...

journal_title：Journal of clinical pathology

authors： Sharma M,Grieve JH

更新日期：2006-04-01 00:00:00

abstract：:A new rapid automated method for the identification and classification of microorganisms is described. It is based on the incorporation of 35S-methionine into cellular proteins and subsequent separation of the radiolabelled proteins by sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE). The protein ...

journal_title：Journal of clinical pathology

authors： Tabaqchali S,Silman R,Holland D

更新日期：1987-09-01 00:00:00

abstract：AIMS:To describe characteristics of a series of people accidentally and deliberately killed by air powered weapons. METHODS:Five cases of fatal airgun injury were identified by forensic pathologists and histopathologists. The circumstances surrounding the case, radiological examination, and pathological findings are d...

journal_title：Journal of clinical pathology

authors： Milroy CM,Clark JC,Carter N,Rutty G,Rooney N

更新日期：1998-07-01 00:00:00

abstract：:The need for separate swab transport methods for aerobes and anaerobes may result in inadequate transport of specimens for anaerobic bacteriology. Most microbiology laboratories in Australia rely on Stuart's transport medium to protect anaerobic bacteria. This paper presents a new, simple transport medium (Transport D...

journal_title：Journal of clinical pathology

authors： Alfa M,Lee A

更新日期：1982-05-01 00:00:00

abstract：:A modified nitroblue tetrazolium test (NBT) is described which is suitable for routine application in the haematology or bacteriology laboratory and which provides a rapid aid to the diagnosis of bacterial infection. Hitherto published methods have recommended the use of heparinized whole blood samples for the perform...

journal_title：Journal of clinical pathology

authors： Gordon AM,Rowan RM,Brown T,Carson HG

更新日期：1973-01-01 00:00:00

abstract：BACKGROUND/AIMS:In the natural history of gastric cancer, non-invasive neoplasia (NiN) precedes invasive carcinoma. A histological classification of gastric NiN has recently been proposed by a World Health Organisation international panel of experts. Genetic instability is known to be among the molecular pathways invol...

journal_title：Journal of clinical pathology

authors： Rugge M,Bersani G,Bertorelle R,Pennelli G,Russo VM,Farinati F,Bartolini D,Cassaro M,Alvisi V

更新日期：2005-08-01 00:00:00

abstract：:A post-mortem examination, in the case of a 34-year-old man dying suddenly from head injuries sustained in a road accident, showed early cirrhosis of the liver and associated splenomegaly 17 years after an attack of infective hepatitis. The histology of the thymus showed abnormal changes in the medulla, consisting of ...

journal_title：Journal of clinical pathology

authors： CORRIDAN M

更新日期：1963-09-01 00:00:00

abstract：BACKGROUND:Malignant deciduoid mesothelioma is a rare variant of epithelioid mesothelioma. This tumour generally has poor prognosis, and can be asbestos related. AIM:To identify peculiar genetic changes responsible for critical phases in pathogenesis of malignant deciduoid mesothelioma and their prognostic relevance. ...

journal_title：Journal of clinical pathology

authors： Scattone A,Pennella A,Gentile M,Musti M,Nazzaro P,Buonadonna AL,Marzullo A,Cavone D,Pollice L,Serio G

更新日期：2006-07-01 00:00:00

abstract：:A clinical study of 401 cases of tumour of salivary tissue has been made and the results reported, together with a review of the literature. The histological variations of such tumours are classified and discussed. ...

journal_title：Journal of clinical pathology

authors： CAMERON JM

更新日期：1961-05-01 00:00:00

abstract：BACKGROUND:Periostin is a secreted adhesion protein, normally expressed in mesenchime-derived cells. Aberrant expression of the periostin gene in epithelial tumours seems to play a role in angiogenesis and metastases. AIMS:To investigate periostin expression in a consecutive series of breast carcinomas and correlate i...

journal_title：Journal of clinical pathology

authors： Puglisi F,Puppin C,Pegolo E,Andreetta C,Pascoletti G,D'Aurizio F,Pandolfi M,Fasola G,Piga A,Damante G,Di Loreto C

更新日期：2008-04-01 00:00:00