Adenocarcinoma of the anal glands.

abstract：OBJECTIVES:As the best characterised cancer/testis antigen family members, melanoma-associated antigens (MAGE) have been reported to be expressed in various malignant tumours. However, the expression pattern of MAGE-A family in lung adenocarcinoma (LAC) specimens and their prognostic and therapeutic significance for pa...

journal_title：Journal of clinical pathology

authors： Sang M,Gu L,Yin D,Liu F,Lian Y,Zhang X,Liu S,Huang W,Wu Y,Shan B

更新日期：2017-06-01 00:00:00

abstract：:Serum haptoglobin levels have been studied in patients with a number of haemolytic disorders. In general, serum haptoglobins were low in patients with increased haemolysis. Values were reduced irrespective of whether haemolysis occurred intravascularly or extravascularly. The reduction was related to the amount of hae...

journal_title：Journal of clinical pathology

authors： Owen JA,de Gruchy GC,Smith H

更新日期：1960-11-01 00:00:00

abstract：:Meningitis due to Gemella haemolysans developed in a 73 year old woman after thermolysis of the Gasserian ganglion for trigeminal neuralgia. The taxonomy of this organism is discussed, and previous cases of infection are reviewed. ...

journal_title：Journal of clinical pathology

authors： Mitchell RG,Teddy PJ

更新日期：1985-05-01 00:00:00

abstract：:Two aspects of handwashing in hospital were considered. A study was carried out to examine the contamination of bar soap and containers, and the use of antiseptic soaps in reducing the resident flora of the skin. Swabs were collected from soap dishes on six wards and from a bacteriology laboratory on four consecutive ...

journal_title：Journal of clinical pathology

authors： Jarvis JD,Wynne CD,Enwright L,Williams JD

更新日期：1979-07-01 00:00:00

abstract：:Numerous clinical pathology departments are deploying or planning to deploy digital pathology systems for all or part of their diagnostic output. Digital pathology is an evolving technology, and it is important that departments uphold or improve on current standards. Leeds Teaching Hospitals NHS Trust has been scannin...

journal_title：Journal of clinical pathology

authors： Williams BJ,Treanor D

更新日期：2020-07-01 00:00:00

abstract：:Experiments were performed to evaluate five commercial kit assays used for the detection of antibodies to dsDNA. The kits were compared using a performance index score as recommended by the guidelines of the European Committee for Clinical Laboratory Standards. The highest performance score was obtained using the radi...

journal_title：Journal of clinical pathology

authors： McMillan SA,Fay AC

更新日期：1988-11-01 00:00:00

abstract：:Cell surface proteolysis is an important mechanism for generating biologically active proteins that mediate a range of cellular functions and contribute to biological processes such as angiogenesis. Although most studies have focused on the plasminogen system and matrix metalloproteinases (MMPs), recently there has be...

journal_title：Journal of clinical pathology

authors： Noel A,Maillard C,Rocks N,Jost M,Chabottaux V,Sounni NE,Maquoi E,Cataldo D,Foidart JM

更新日期：2004-06-01 00:00:00

abstract：:A young woman presented with bilateral ovarian tumours. Multiple sections of each tumour were shown to many pathologists for consultation; some considered the tumours to be borderline, whereas others thought that one or both of them was malignant. Morphometry showed that the numerical classification probabilities for ...

journal_title：Journal of clinical pathology

authors： Baak JP,Van der Ley G

更新日期：1984-10-01 00:00:00

abstract：:The results of an investigation show that there is no statistically significant excess of blood group A in cases of carcinoma of the oesophagus or in cases of benign prostatic hyperplasia. ...

journal_title：Journal of clinical pathology

authors： BEASLEY WH

更新日期：1964-01-01 00:00:00

abstract：:Malignant extrarenal rhabdoid tumour (MERT) of the gastrointestinal tract is rarely reported in the literature. This report describes the clinical and pathological features of a malignant rhabdoid tumour of the oesophagus in a Chinese man. Ivor-Lewis oesophagectomy had been performed. The tumour behaved aggressively a...

journal_title：Journal of clinical pathology

authors： Ng WC,Leong HT,Ma KF,Yip WL,Suen WM

更新日期：2003-09-01 00:00:00

abstract：:The ultrastructure of the osteocytes, osteoblasts, osteoclasts, haemopoietic and other connective tissue cells was examined in 27 biopsies from 22 patients with Paget's disease of bone. Electron microscopy showed characteristic nuclear and cytoplasmic inclusions in the osteoclasts of all of the 25 biopsies exhibiting ...

journal_title：Journal of clinical pathology

authors： Harvey L,Gray T,Beneton MN,Douglas DL,Kanis JA,Russell RG

更新日期：1982-07-01 00:00:00

abstract：:The Human Leukocyte Antigen (HLA) system plays a critical role in regulating the immune response. As a consequence of its role in immune regulation and exquisite polymorphism, the HLA system also constitutes an immunological barrier which must be avoided or otherwise overcome in clinical transplantation. This introduc...

journal_title：Journal of clinical pathology

authors： Howell WM,Carter V,Clark B

更新日期：2010-05-01 00:00:00

abstract：:Clinical trials have shown that many patients with breast cancer with limited sentinel lymph node (SLN) metastatic disease can safely avoid axillary lymph node dissection. Ultra-staging of initially negative SLNs may not confer additional clinical benefit. Despite this, protocols of 'enhanced pathological examination'...

journal_title：Journal of clinical pathology

authors： Murray C,Al Shehhi A,Ó'Riain C,Dunne B,Maguire A

更新日期：2020-10-22 00:00:00

abstract：AIMS:The assessment of lymphatic vessel density (LVD) has been suggested as a tool to determine the metastatic risk of neoplasias. On this premise, the authors aimed to verify whether progression risk of stage I colorectal cancer may be related to LVD. The authors also evaluated and correlated vascular endothelial grow...

journal_title：Journal of clinical pathology

authors： Barresi V,Reggiani-Bonetti L,Di Gregorio C,De Leon MP,Barresi G

更新日期：2011-01-01 00:00:00

abstract：AIMS:To investigate the physical status of human papillomavirus 16 (HPV-16) in low grade squamous intraepithelial lesions (LSILs) as a means of determining the percentage of viral integration. METHODS:Ninety two LSIL/HPV positive Thin Prep(TM) samples were initially tested for the E6 gene by the polymerase chain react...

journal_title：Journal of clinical pathology

authors： Gallo G,Bibbo M,Bagella L,Zamparelli A,Sanseverino F,Giovagnoli MR,Vecchione A,Giordano A

更新日期：2003-07-01 00:00:00

abstract：:Common acute lymphoblastic leukaemia antigen (CALLA) was first characterised in lymphoid leukaemic cells. The antigen is present in different stages of lymphoid cell differentiation as well as in subsets of myeloid cells, and further studies have also shown its presence in non-lymphoid tissues. The recent cloning and ...

journal_title：Journal of clinical pathology

authors： Loke SL,Leung CY,Chiu KY,Yau WL,Cheung KN,Ma L

更新日期：1990-08-01 00:00:00

abstract：:The changes occurring at the periphery of invasive cervical carcinomas have been studied in detail, with particular reference to the incidence of preinvasive carcinoma. The various criteria used in the cytological diagnosis of malignancy have been evaluated, and the implications of large cytological screening programm...

journal_title：Journal of clinical pathology

authors： MEYER PC

更新日期：1965-07-01 00:00:00

abstract：:A method for the simultaneous labelling of terminal deoxynucleotidyl transferase (TdT) and membrane antigens is described. TdT is visualised in the cell nucleus with the peroxidase-antiperoxidase (PAP) method, and the immunogold method is used in combination with monoclonal antibodies against membrane antigens. The mo...

journal_title：Journal of clinical pathology

authors： Tavares de Castro J,San Miguel JF,Soler J,Catovsky D

更新日期：1984-06-01 00:00:00

abstract：INTRODUCTION:Modification of the spiral arteries with loss of the muscular vascular wall, invaded by the trophoblasts, represents the goal of the physiological vascular adaptation during human implantation. When physiological vascular changes do not occur, an unfavourable evolution of gestation may develop as suggested...

journal_title：Journal of clinical pathology

authors： Avagliano L,Bulfamante GP,Morabito A,Marconi AM

更新日期：2011-12-01 00:00:00

abstract：AIMS:To evaluate the prognostic impact of the width of negative surgical margins (NSM) and associated and preinvasive lesions at the NSM in patients with penile squamous cell cancer (PSC). METHODS:Enrolling 87 patients with NSM who underwent surgery for PSC, the archived margin slides and entirely wax-embedded surgica...

journal_title：Journal of clinical pathology

authors： Gunia S,Koch S,Jain A,May M

更新日期：2014-03-01 00:00:00

abstract：:A biological method for detecting streptococcal nicotinamide adenine dinucleotide glycohydrolase (NADG) is presented, based on its ability to inhibit the growth of Haemophilus parainfluenzae. Three hundred clinical isolates of beta-haemolytic streptococci were tested. All isolates producing NADG belonged to Lancefield...

journal_title：Journal of clinical pathology

authors： Green NE

更新日期：1979-06-01 00:00:00

abstract：AIMS:To evaluate the role of hepatocyte expression of leucocyte adhesion molecules and major histocompatibility complex (MHC) antigens in the pathogenesis of chronic viral hepatitis. METHODS:The expression of intercellular adhesion molecule 1 (ICAM-1), lymphocyte function associated antigen 3 (LFA-3), and MHC class I ...

journal_title：Journal of clinical pathology

authors： Chu CM,Liaw YF

更新日期：1993-11-01 00:00:00

abstract：:Three cases of fungal endocarditis are described, each following a homograft valve replacement for aortic stenosis. The causative organism was C. albicans. The characteristic findings included soft, easily detached vegetations consisting of fungal colonies, aneurysms, embolization of large vessels, and lack of respons...

journal_title：Journal of clinical pathology

authors： McConnell EM,Roberts C

更新日期：1967-07-01 00:00:00

abstract：:An immunological method for detecting fibrin degradation products by tanned cells agglutination has been standardized. The effects of different variables, such as cell concentration, pH, and length of incubation, and the specificity of the reaction, are described. The method is compared with other immunological techni...

journal_title：Journal of clinical pathology

authors： Das PC

更新日期：1970-05-01 00:00:00

abstract：:The amyloid deposits in 21 renal biopsy specimens were subjected to a detailed immunohistochemical analysis using a panel of antibodies against recognised constituents of tissue amyloid. This was a retrospective study of material originally submitted during the investigation of various renal abnormalities and studied ...

journal_title：Journal of clinical pathology

authors： Fitzmaurice RJ,Bartley C,McClure J,Ackrill P

更新日期：1991-03-01 00:00:00

abstract：:The simultaneous estimation of steroids in plasma was carried out by the assay of cortisol, corticosterone, and testosterone. The method entails separation by means of thin layer chromatography, followed by conversion to a fluorophore and fluorimetric measurement. Its major advantages are its high specificity, its abi...

journal_title：Journal of clinical pathology

authors： Mattingly D,Martin H,Tyler C

更新日期：1989-06-01 00:00:00

abstract：:A study has been made by clinical methods and by bio-assay of the effectiveness of a régime for prophylaxis against tetanus. The two principal objects of the method were to ensure that active immunization was offered to all patients who had received antitoxin and to measure the effect of the combined administration of...

journal_title：Journal of clinical pathology

authors： LAURENCE M,HOLT LB,GRAHAM CE,BONNEY GL

更新日期：1965-01-01 00:00:00

abstract：:Monoclonal antibodies to factor VIII antigen (VIII:Ag) and von Willebrand factor (vWf:Ag) were immobilised on Sephacryl S-1000 and tested for their ability to deplete normal human citrated plasma of factor VIII. A combination of two antibodies to VIII:Ag and one antibody to vWf:Ag was required to produce plasma contai...

journal_title：Journal of clinical pathology

authors： Hornsey VS,Waterston YG,Prowse CV

更新日期：1988-05-01 00:00:00

abstract：:A locally developed, computer-based clinical chemistry laboratory system has been in operation since 1970. This utilises a Digital Equipment Co Ltd PDP 12 and an interconnected PDP 8/F computer. Details are presented of the performance and quality control techniques incorporated into the system. Laboratory performance...

journal_title：Journal of clinical pathology

authors： Undrill PE,Frazer SC

更新日期：1979-02-01 00:00:00

abstract：:The proportion of fimbriate strains amongst Escherichia coli freshly isolated from infected urines did not differ significantly from the proportion amongst commensal Esch. coli isolated from the bowel and from non-infected urines. It is concluded that fimbriae play no major role in the pathogenesis of Esch. coli urina...

journal_title：Journal of clinical pathology

authors： Buck AC

更新日期：1967-01-01 00:00:00