An approach to quality and performance control in a computer-assisted clinical chemistry laboratory.

abstract：BACKGROUND:The terminology applied to vascular anomalies has been variable in previously published literature making interpretation suboptimal. The International Society for the Study of Vascular Anomalies (ISSVA) has proposed a revised classification based on clinical features and histopathological findings. This clas...

journal_title：Journal of clinical pathology

authors： Al-Adnani M,Williams S,Rampling D,Ashworth M,Malone M,Sebire NJ

更新日期：2006-12-01 00:00:00

abstract：:Improvements in the Zimmermann reaction are effected by using methanol as a solvent for the reagents employed in the reaction in place of ethanol or aqueous ethanol. The advantages are as follows. Considerably lower blanks are obtained; extraneous chromogens are negligible at the wavelength of measurement, so that no ...

journal_title：Journal of clinical pathology

authors： BEALE RN,BOSTROM JO,CROFT D

更新日期：1962-11-01 00:00:00

abstract：:Members of a newly recognized group of hospital staphylococci, which are believed to have arisen from 83A staphylococci by lysogenization, differ from them in several cultural characters. Some but not all of these characters appear to be determined by the carriage of phage. ...

journal_title：Journal of clinical pathology

authors： Jevons MP,John M,Parker MT

更新日期：1966-07-01 00:00:00

abstract：OBJECTIVES:To evaluate the protein expression of connexin 43 (Cx43) in primary urothelial bladder cancer and test its association with the histopathological characteristics and clinical outcome. METHODS:A tissue microarray containing 348 tissue samples from 174 patients with primary urothelial carcinomas of the bladde...

journal_title：Journal of clinical pathology

authors： Poyet C,Buser L,Roudnicky F,Detmar M,Hermanns T,Mannhard D,Höhn A,Rüschoff J,Zhong Q,Sulser T,Moch H,Wild PJ

更新日期：2015-10-01 00:00:00

abstract：:Sclerochoroidal calcification is an uncommon condition. Metabolic evaluation and clinical examination are important to exclude associated systemic conditions such as the Bartter and Gitelman syndromes. It has been suggested that the lesions seen in sclerochoroidal calcification are calcium pyrophosphate dihydrate crys...

journal_title：Journal of clinical pathology

authors： Gupta R,Hu V,Reynolds T,Harrison R

更新日期：2005-12-01 00:00:00

abstract：:Thirty-seven percutaneous renal biopsies showing no significant abnormalities on light microscopy were studied electron optically and by immunofluorescence when available. Assessment of the pathological material was followed by analysis of the patients' clinical notes, and a clinicopathological correlation was carried...

journal_title：Journal of clinical pathology

authors： Lawler W,Tarpey P,Williams G,Acheson EJ,Mallick NP

更新日期：1976-05-01 00:00:00

abstract：:A case of abnormal chromatin clumping (ACC) which arose during the course of a myelodysplastic/myeloproliferative syndrome is described in a 61 year old woman who died of haemorrhage 43 months after diagnosis. Mature granulocytes exhibited the same nuclear abnormality described in other patients reported. Unusually, s...

journal_title：Journal of clinical pathology

authors： Gardais J

更新日期：1993-02-01 00:00:00

abstract：:The aim of this article is to provide knowledge of the origin of catecholamines and metabolites so that there can be an informed approach to the methods for biochemical screening for a possible phaeochromocytoma; The article includes a review of catecholamine and metadrenaline metabolism, with methods used in biochemi...

journal_title：Journal of clinical pathology

authors： Barron J

更新日期：2010-08-01 00:00:00

abstract：:Serum total calcium was measured in 1693 patients during a four-month period. We examined the effects of adjustment for albumin concentration on the interpretation of single measurements of serum total calcium and on the variation of series of measurements in individual patients. Markedly abnormal total calcium concen...

journal_title：Journal of clinical pathology

authors： Payne RB,Carver ME,Morgan DB

更新日期：1979-01-01 00:00:00

abstract：:Synovial sarcoma is a distinctive soft tissue neoplasm with monophasic and biphasic forms. It is typically a deep-seated soft tissue tumour of the extremities of young adults and occasional cases have been described in large peripheral nerves. A rare example has a predominance of the glandular component and may mimic ...

journal_title：Journal of clinical pathology

authors： Weinreb I,Perez-Ordoñez B,Guha A,Kiehl TR

更新日期：2008-05-01 00:00:00

abstract：AIM:To assess the reliability of local international normalised ratios (INR) using a set of three international reference preparation (IRP) certified freeze dried plasmas. METHODS:55 centres in the United Kingdom and the Republic of Ireland participated; 36 centres employed coagulometers and 19 a manual prothrombin ti...

journal_title：Journal of clinical pathology

authors： Poller L

更新日期：1998-05-01 00:00:00

abstract：:A sensitive gas chromatography-mass spectrometric method was used to measure the generation in whole blood of leukotriene B4 (LTB4), a potent stimulator of neutrophil chemotaxis, in eight patients with chronic granulocytic leukaemia (CGL) and 12 healthy controls. LTB4 was detectable in unstimulated samples from all th...

journal_title：Journal of clinical pathology

authors： Reilly IA,Knapp HR,Fitzgerald GA

更新日期：1988-11-01 00:00:00

abstract：AIMS:The aim of the present study was to immunohistochemically investigate the expression and prognostic significance of putative cancer stem cell markers CD117 (c-kit), CD34, CD20 and CD15 in a cohort of patients with primary choroidal and ciliary body melanoma. METHODS:The immunohistochemical expression of these mar...

journal_title：Journal of clinical pathology

authors： Lukenda A,Dotlic S,Vukojevic N,Saric B,Vranic S,Zarkovic K

更新日期：2016-03-01 00:00:00

abstract：AIM:Ultraviolet light (UV) is known to cause DNA damage in the epidermis. The damaged DNA is repaired or deleted by apoptosis to prevent the generation of cancer. It has been suggested that a deficient apoptotic mechanism may predispose individuals to skin cancer. Therefore, the response of normal controls and patients...

journal_title：Journal of clinical pathology

authors： Murphy M,Mabruk MJ,Lenane P,Liew A,McCann P,Buckley A,O Flatharta C,Hevey D,Billet P,Robertson W,Javed S,Leader M,Kay E,Murphy GM

更新日期：2002-11-01 00:00:00

abstract：AIMS:To assess the accuracy of the Mast-ID 15 system compared with API 20 E for the identification of stock and fresh clinical strains of Enterobacteriaceae and Acinetobacter spp; to compare the accuracy of 19 pin and 36 pin multipoint inoculator heads. METHODS:One hundred frozen stock cultures of Enterobacteriaceae a...

journal_title：Journal of clinical pathology

authors： Shakespeare AP,Megson GM,Jones PA,Drucker DB,Keaney MG,Ganguli LA

更新日期：1992-02-01 00:00:00

abstract：:A patient with rhabdomyosarcoma is described in whom the presenting clinical and laboratory features were those of disseminated intravascular coagulation. The patient's rapid downhill course was primarily expressed by haemorrhagic tendency. An alveolar rhabdomyosarcoma, affecting many organs, including vascular and ca...

journal_title：Journal of clinical pathology

authors： Eldor A,Naparstek E,Boss JH,Biran S

更新日期：1977-07-01 00:00:00

abstract：:A commercial latex slide test (Oxoid DR 620) for the identification of Escherichia coli O157 was compared with a standard tube agglutination method using E coli O157 antiserum (Difco). Thirty isolates previously confirmed as E coli O157 were positive by both methods: 30 isolates of E coli of serogroups other than O157...

journal_title：Journal of clinical pathology

authors： Chapman PA

更新日期：1989-10-01 00:00:00

abstract：:In this necropsy review of 37 cases of acute pancreatitis, evidence is presented that there are at least two different initiating mechanisms in acute necrotising pancreatitis in man. Firstly, there is primary duct inflammation, with subsequent inflammation and necrosis of the pancreatic parenchyma surrounding the excr...

journal_title：Journal of clinical pathology

authors： Foulis AK

更新日期：1980-12-01 00:00:00

abstract：AIMS:Myospherulosis is a rare condition characterised by sac-like structures containing spheroid bodies in cysts or cystic spaces in the tissue. This condition has not previously been reported in the liver. The association with previous portal vein embolisation using a mixture of butyl 2-cyanoacrylate and ethiodised oi...

journal_title：Journal of clinical pathology

authors： Lui PC,Luk IS,Lee CK,Lui YH,Leung CY,Choi CH

更新日期：2004-02-01 00:00:00

abstract：AIMS:To assess the clinical efficacy of diagnostic procedures for breast cancer at a teaching hospital using internal auditing tools and quality control measures. METHODS:A retrospective assessment of 500 patients who underwent core needle biopsy (wide-bore needle biopsy; WBN) of palpable or non-palpable breast nodes ...

journal_title：Journal of clinical pathology

authors： Verenhitach BD,Elias S,Patrocínio AC,Nazário AC,Waizberg A

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Cytokeratin immunohistochemistry (IHC) reveals a higher rate of occult lymph node metastases among lobular carcinomas than among ductal breast cancers. IHC is widely used but is seldom recommended for the evaluation of sentinel lymph nodes in breast cancer patients. OBJECTIVE:To assess the value of cytokera...

journal_title：Journal of clinical pathology

authors： Cserni G,Bianchi S,Vezzosi V,Peterse H,Sapino A,Arisio R,Reiner-Concin A,Regitnig P,Bellocq JP,Marin C,Bori R,Penuela JM,Iturriagagoitia AC

更新日期：2006-05-01 00:00:00

abstract：AIMS:Mitochondrial diseases form one of the largest groups of inborn errors of metabolism. The birth prevalence is approximately 1/5000 in well-studied populations, but little has been reported from Sub-Saharan Africa. The aim of this study was to describe the genetics underlying mitochondrial disease in South Africa. ...

journal_title：Journal of clinical pathology

authors： Meldau S,Owen EP,Khan K,Riordan GT

更新日期：2020-10-28 00:00:00

abstract：AIM:Nowadays, extracellular vesicles are of great interest in prostate cancer (PCa) research. Asparagine (N)-linked glycosylation could play a significant role in the pathological mechanism of these vesicles. We investigated if prostatic protein N-glycosylation profiles were related to urinary vesicle-associated prosta...

journal_title：Journal of clinical pathology

authors： Vermassen T,D'Herde K,Jacobus D,Van Praet C,Poelaert F,Lumen N,Callewaert N,Decaestecker K,Villeirs G,Hoebeke P,Van Belle S,Rottey S,Delanghe J

更新日期：2017-10-01 00:00:00

abstract：AIMS:The aims of the study were to compare bacterial recovery following storage of sputum samples at 20 degrees C room temperature and 4 degrees C (refrigerated) for 24 h, and to determine the effect of postage on viable bacterial numbers. METHODS:A total of 38 individual sputum samples from clinically stable patients...

journal_title：Journal of clinical pathology

authors： Pye A,Hill SL,Bharadwa P,Stockley RA

更新日期：2008-03-01 00:00:00

abstract：INTRODUCTION:Whole slide images (WSI) have been used in many pathology applications such as teleconsultation, teaching and research, but not in primary diagnostics. The aim of this study was to test the feasibility of using WSI in primary diagnostics of paediatric pathology specimens and placental tissue. MATERIALS AN...

journal_title：Journal of clinical pathology

authors： Al-Janabi S,Huisman A,Nikkels PG,ten Kate FJ,van Diest PJ

更新日期：2013-03-01 00:00:00

abstract：AIMS:Computational pathology platforms incorporate digital microscopy with sophisticated image analysis to permit rapid, continuous measurement of protein expression. We compared two computational pathology platforms on their measurement of breast tumour oestrogen receptor (ER) and progesterone receptor (PR) expression...

journal_title：Journal of clinical pathology

authors： Ahern TP,Beck AH,Rosner BA,Glass B,Frieling G,Collins LC,Tamimi RM

更新日期：2017-05-01 00:00:00

abstract：:A case of coexistent acute myeloid leukaemia and sarcoidosis is reported. This was complicated by recurrent pulmonary haemorrhage during reinduction and consolidation chemotherapy. A review of published papers on malignancy and sarcoidosis, in particular acute leukaemia is given. The outcome of most cases of acute leu...

journal_title：Journal of clinical pathology

authors： Williams B,Francis A,Durrant S

更新日期：1994-07-01 00:00:00

abstract：:A case of extramedullary myeloblastic transformation of chronic myeloid leukaemia is reported. This was characterised by an unusual clinical and haematological course and showed a unique cytogenetic pattern. ...

journal_title：Journal of clinical pathology

authors： Flanagan NG,Harrison CJ,Harry DS,Ridway JC

更新日期：1985-07-01 00:00:00

abstract：:Four cases of human infection with Achromobacter anitratus, one of which was fatal, are described. They all occurred at one hospital within a period of two months. The bacteriology, antibiotic sensitivity, and pathogenicity of the organisms are discussed. One of the strains was found to differ from the other three. ...

journal_title：Journal of clinical pathology

authors： ASHLEY DJ,KWANTES W

更新日期：1961-11-01 00:00:00

abstract：:Tests of iron and folate nutrition have been carried out in early pregnancy and at delivery in 63 Bantu females. Accepted normal values for serum iron, and percentage saturation of transferrin, but not for unsaturated iron-binding capacity, for non-pregnant subjects were found to apply equally well in pregnancy. Conco...

journal_title：Journal of clinical pathology

authors： Metz J,Turchetti L,Combrink B,Krawitz S

更新日期：1966-03-01 00:00:00