Extramedullary transformation of chronic myeloid leukaemia with a unique chromosome pattern.

abstract：AIMS:To investigate proliferative activity in leukaemic and lymphomatous bone marrow infiltrates and to assess the feasibility of transport of specimens among institutions. METHODS:Proliferative activity in bone marrow trephine cryosections from 99 patients with non-Hodgkin's lymphoma (NHL), 23 patients with acute mye...

journal_title：Journal of clinical pathology

authors： White DM,Smith AG,Smith JL

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:Venous invasion (VI) is an important prognosis predictor after colorectal carcinoma (CRC) resection, enabling more accurate staging and influencing postoperative management. AIMS:To assess/compare various tissue block types (perpendicular, tangential, across mesentery (AM), from major vessels or lymph nodes...

journal_title：Journal of clinical pathology

authors： Sternberg A,Mizrahi A,Amar M,Groisman G

更新日期：2006-02-01 00:00:00

abstract：AIMS:Determine whether a simple prewash step will provide adequate amounts of high-quality DNA from core needle biopsies for molecular sequencing studies. METHODS:The quantitative and qualitative metrics of DNA recovered from core needle biopsies processed either by 1) formalin fixation and paraffin embedding (FFPE), ...

journal_title：Journal of clinical pathology

authors： Mojica WD,Hou T,Sykes D,Dey-Rao R

更新日期：2017-06-01 00:00:00

abstract：:The incidence of jaundice and of abnormal liver function tests has been assessed in 91 multitransfused patients with severe haemophilia A and B. Tests of hepatocyte function were within the normal range in the majority of patients. On the contrary, tests of biliary cell function, liver cell damage, and bromsulphthalei...

journal_title：Journal of clinical pathology

authors： Mannucci PM,Capitanio A,Del Ninno E,Colombo M,Pareti F,Ruggeri ZM

更新日期：1975-08-01 00:00:00

abstract：:Digital pathology (DP) and whole-slide imaging (WSI) technology have matured substantially over the last few years and there is growing evidence from validation studies that WSI is comparable to glass slides for histopathology diagnosis, although with some limitations, which can be appropriately minimised. Whether the...

journal_title：Journal of clinical pathology

authors： Cheng CL,Tan PH

更新日期：2017-05-01 00:00:00

abstract：:Two isolates of Proteus mirabilis and four of Esch. coli which would not grow on commonly used commercial sensitivity test media are reported. These organisms appear to be resistant to co-trimoxazole, are exacting towards thymidine, and five of six were isolated from patients who had been treated with co-trimoxazole. ...

journal_title：Journal of clinical pathology

authors： Barker J,Healing D,Hutchison JG

更新日期：1972-12-01 00:00:00

abstract：:It was postulated that the short chain fatty acids (SCFA) produced by anaerobic bacteria might serve as microbial markers in purulent material. Eighteen pus specimens from various sources were analysed by gas-liquid chromatography (GLC), and the SCFA detected were compared with the microorganisms isolated by conventio...

journal_title：Journal of clinical pathology

authors： Ladas S,Arapakis G,Malamou-Ladas H,Palikaris G,Arseni A

更新日期：1979-11-01 00:00:00

abstract：:Two cancer-associated proteins, carcinoembryonic antigen (CEA) and pregnancy-associated alpha2 glycoprotein (PAG), together with 13 normal serum proteins were measured in the serum and effusion fluid of patients with ascites and pleural effusions. The results indicate that CEA measurement in effusion fluid is more eff...

journal_title：Journal of clinical pathology

authors： Booth SN,Lakin G,Dykes PW,Burnett D,Bradwell AR

更新日期：1977-06-01 00:00:00

abstract：:A polyclonal antiserum, produced in sheep and reactive against purified human leucocyte elastase, has been applied to paraffin sections from a range of human tissues by means of the indirect immunoperoxidase method. Striking and consistent results have been obtained. Normal or inflammatory granulocytes were intensely ...

journal_title：Journal of clinical pathology

authors： Crocker J,Jenkins R,Burnett D

更新日期：1984-10-01 00:00:00

abstract：:Microsatellite instability (MSI) testing is tricky in gynaecological cancers (GC). Thus, we aimed to describe the instability patterns to improve MSI test interpretation in sporadic and hereditary GCs. Ninety-five cases, including uterine and ovarian cancers, with known genetic and immunohistochemical (IHC) features, ...

journal_title：Journal of clinical pathology

authors： Libera L,Sahnane N,Carnevali IW,Cimetti L,Cerutti R,Chiaravalli AM,Riva C,Tibiletti MG,Sessa F,Furlan D

更新日期：2017-09-01 00:00:00

abstract：:Superficial inflammatory dermatoses are very common and comprise a wide, complex variety of clinical conditions. Accurate histological diagnosis, although it can sometimes be difficult to establish, is essential for clinical management. Knowledge of the microanatomy of the skin is important to recognise the variable h...

journal_title：Journal of clinical pathology

authors： Alsaad KO,Ghazarian D

更新日期：2005-12-01 00:00:00

abstract：:Members of a newly recognized group of hospital staphylococci, which are believed to have arisen from 83A staphylococci by lysogenization, differ from them in several cultural characters. Some but not all of these characters appear to be determined by the carriage of phage. ...

journal_title：Journal of clinical pathology

authors： Jevons MP,John M,Parker MT

更新日期：1966-07-01 00:00:00

abstract：:Only four cases of tracheopathia osteoplastica have been reported in Britain in the past 110 years. Ten further cases are now reported; in two the diagnosis was made at bronchoscopy. It is suggested that the reputed rarity of the condition in Britain is not the whole picture. ...

journal_title：Journal of clinical pathology

authors： Way SP

更新日期：1967-11-01 00:00:00

abstract：:When the posture was changed from horizontal to vertical, or the reverse, the alteration in plasma volume and in the levels of haematocrit, haemoglobin, and plasma protein was much greater in patients with oedema or low plasma protein or albumin concentrations ("the pathological group") than in patients without these ...

journal_title：Journal of clinical pathology

authors： FAWCETT JK,WYNN V

更新日期：1960-07-01 00:00:00

abstract：AIMS:The localisation of the translocation breakpoint of the Ewing sarcoma family of tumours shows significant variability on relatively large regions of fusion partner genes. As a consequence, many alternative forms of EWSR1-ETS translocation exist which make the RNA-based molecular diagnostics of Ewing sarcoma family...

journal_title：Journal of clinical pathology

authors： Patócs B,Németh K,Garami M,Arató G,Kovalszky I,Szendroi M,Fekete G

更新日期：2012-12-01 00:00:00

abstract：AIM:To determine whether the pattern of involvement of the gastric mucosa in lymphocytic gastritis is predictive of the presence or absence of duodenal pathology. METHODS:50 cases (M:F, 26:24; median age 57 years) diagnosed as lymphocytic gastritis between 1986 and 1998 with concurrent duodenal (D2) biopsies were iden...

journal_title：Journal of clinical pathology

authors： Hayat M,Arora DS,Wyatt JI,O'Mahony S,Dixon MF

更新日期：1999-11-01 00:00:00

abstract：AIM:Recent events surrounding postmortem practices have necessitated several changes in the way necropsies are conducted both within the medicolegal and hospital settings. These changes have resulted in a striking reduction in the frequency of brain retention for neuropathological examination. Aberdeen Royal Infirmary,...

journal_title：Journal of clinical pathology

authors： Sharma M,Grieve JH

更新日期：2006-04-01 00:00:00

abstract：:Methods of speciating Candida isolates from clinical specimens are described and the necessity of speciation is emphasized. Differences in susceptibility of C. albicans and C. tropicalis to amphotericin B were observed and the implications of this in relation to treatment with amphotericin B and the development of res...

journal_title：Journal of clinical pathology

authors： Stieritz DD,Law EJ,Holder IA

更新日期：1973-06-01 00:00:00

abstract：:A locally developed, computer-based clinical chemistry laboratory system has been in operation since 1970. This utilises a Digital Equipment Co Ltd PDP 12 and an interconnected PDP 8/F computer. Details are presented of the performance and quality control techniques incorporated into the system. Laboratory performance...

journal_title：Journal of clinical pathology

authors： Undrill PE,Frazer SC

更新日期：1979-02-01 00:00:00

abstract：:The nitroblue tetrazolium (NBT) test has been evaluated as a means of differentiating episodes of infection and rejection in 10 cadaver kidney transplant recipients. Normal NBT values were observed during all 11 episodes of acute rejection. A significant elevation of the NBT score was encountered in six of eight episo...

journal_title：Journal of clinical pathology

authors： Gordon AM,Briggs JD,Bell PR

更新日期：1974-09-01 00:00:00

abstract：:Four cases of human infection with Achromobacter anitratus, one of which was fatal, are described. They all occurred at one hospital within a period of two months. The bacteriology, antibiotic sensitivity, and pathogenicity of the organisms are discussed. One of the strains was found to differ from the other three. ...

journal_title：Journal of clinical pathology

authors： ASHLEY DJ,KWANTES W

更新日期：1961-11-01 00:00:00

abstract：BACKGROUND:Hsulf-1 is a newly identified enzyme with arylsulphatase activity that can regulate the sulphation state of cell-surface heparan sulphate proteoglycans (HSPGs). In vitro overexpression of this enzyme in pancreatic cancer cells decreases responsiveness to fibroblastic growth factor-2, as Hsulf-1 is up regulat...

journal_title：Journal of clinical pathology

authors： Abiatari I,Kleeff J,Li J,Felix K,Büchler MW,Friess H

更新日期：2006-10-01 00:00:00

abstract：:Rosetting and non-rosetting lymphocytes collected from normal individuals were stained for the presence of beta-glucuronidase, periodic-acid Schiff activity, gamma glutamyl transpeptidase, acid phosphatase, and alpha-naphthyl butyrate esterase. Lymphocytes which formed rosettes with sheep erythrocytes and non-rosette ...

journal_title：Journal of clinical pathology

authors： Davey FR,Huntington SJ,Maccallum J,Macmath JM

更新日期：1977-07-01 00:00:00

abstract：:This paper illustrates a simple method of necropsy dissection of the abdominal organs after abdominal surgery. The organs are removed in one block as per the method described by Letulle. A retroperitoneal approach is then used. Structures are dissected away in a series of layers using the vasculature for guidance. Thi...

journal_title：Journal of clinical pathology

authors： Culora GA,Roche WR

更新日期：1996-09-01 00:00:00

abstract：:A post-mortem examination, in the case of a 34-year-old man dying suddenly from head injuries sustained in a road accident, showed early cirrhosis of the liver and associated splenomegaly 17 years after an attack of infective hepatitis. The histology of the thymus showed abnormal changes in the medulla, consisting of ...

journal_title：Journal of clinical pathology

authors： CORRIDAN M

更新日期：1963-09-01 00:00:00

abstract：:Human papillomavirus antigen was found in 39 (16%) of 253 colposcopic biopsies from a group of women at high risk for cervical cancer who had been examined in the early 1970s. Immunohistochemical evidence of papillomavirus infection was found in 20 (30%) of 67 cervical intraepithelial neoplasia lesions infected with w...

journal_title：Journal of clinical pathology

authors： Singer A,Wilters J,Walker P,Jenkins D,Slavin G,Cowdell H,To A,Husain O

更新日期：1985-08-01 00:00:00

abstract：:This study describes a simple whole cell agglutination test for tuberculosis in which phenol-killed Mycobacterium tuberculosis H37Ra is used as the antigen. The test gave positive results in 59 of 63 culture-positive cases of tuberculosis due to M. tuberculosis, and in 4 of 11 culture-positive cases due to other mycob...

journal_title：Journal of clinical pathology

authors： Nicholls AC

更新日期：1975-11-01 00:00:00

abstract：:Temporal changes in gastric antibody response were investigated in 113 (51 men, 62 women) patients with confirmed pernicious anaemia. Their ages ranged from 31-92 years (mean (SD 13.2) 66). At diagnosis, parietal cell antibody and intrinsic factor antibody were detected in 90.9% and 39.1% of all patients, respectively...

journal_title：Journal of clinical pathology

authors： Davidson RJ,Atrah HI,Sewell HF

更新日期：1989-10-01 00:00:00

abstract：:A case of coexistent acute myeloid leukaemia and sarcoidosis is reported. This was complicated by recurrent pulmonary haemorrhage during reinduction and consolidation chemotherapy. A review of published papers on malignancy and sarcoidosis, in particular acute leukaemia is given. The outcome of most cases of acute leu...

journal_title：Journal of clinical pathology

authors： Williams B,Francis A,Durrant S

更新日期：1994-07-01 00:00:00

abstract：:Specimens of muscle were obtained from non-suppurating lesions of nine patients with tropical myositis. When examined in an electron microscope, these revealed patchy myocytolysis with loss of band structure. Perimysial cells were also degenerate. Sections from two out of nine patients revealed intracellular vesicles,...

journal_title：Journal of clinical pathology

authors： Taylor JF,Fluck D,Fluck D

更新日期：1976-12-01 00:00:00